The α1 adrenoceptor antagonist prazosin enhances sleep continuity in fear-conditioned Wistar-Kyoto rats

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 49, Issue , 2014, Pages 7-15

  Laitman, Benjamin M ^a   Gajewski, Nicholas D ^a   Mann, Graziella L ^a   Kubin, Leszek ^a   Morrison, Adrian R ^a   Ross, Richard J ^a,b,c  

^a UNIVERSITY OF PENNSYLVANIA SCHOOL OF VETERINARY MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Fear conditioning; Norepinephrine; Posttraumatic stress disorder; REM sleep; Wistar Kyoto rats

Indexed keywords

PRAZOSIN; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; AROUSAL; ARTICLE; CONDITIONING; CONTROLLED STUDY; DRUG MEGADOSE; ELECTRIC FOOT SHOCK; ELECTRIC SHOCK; ELECTROENCEPHALOGRAPHY; FEAR; FEAR CONDITIONING; FRAGMENTATION REACTION; FREEZING; LATENT PERIOD; MALE; NONHUMAN; NONREM SLEEP; PAIRING TONE; POSTTRAUMATIC STRESS DISORDER; RAT; REM SLEEP; RODENT; SLEEP; SLEEP PARAMETERS; SLEEP WAKING CYCLE; WISTAR KYOTO RAT; ANIMAL; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; ELECTROENCEPHALOGRAM; PHYSIOLOGY; PSYCHOLOGY; SLEEP STAGE; SLEEP WAKE DISORDERS; STRESS DISORDERS, POST-TRAUMATIC; TONIC IMMOBILITY;

ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS; ANIMALS; BRAIN WAVES; CONDITIONING (PSYCHOLOGY); DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; ELECTROSHOCK; FEAR; IMMOBILITY RESPONSE, TONIC; MALE; PRAZOSIN; RATS; RATS, INBRED WKY; SLEEP; SLEEP STAGES; SLEEP WAKE DISORDERS; STRESS DISORDERS, POST-TRAUMATIC;

EID: 84888791426     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2013.11.004     Document Type: Article

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