A fragment of the Escherichia coli ClpB heat-shock protein is a micromolar melanocortin 1 receptor agonist

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 22, 2015, Pages 5306-5308

  Ericson, Mark D ^a   Schnell, Sathya M ^a   Freeman, Katie T ^a   Haskell Luevano, Carrie ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 1 RECEPTOR AGONIST; MELANOCORTIN RECEPTOR AGONIST; PROTEIN CLPB; UNCLASSIFIED DRUG; CLPB PROTEIN, E COLI; CLPB(535-548); ESCHERICHIA COLI PROTEIN; HEAT SHOCK PROTEIN; LIGAND; PEPTIDE FRAGMENT;

ARTICLE; BINDING AFFINITY; CAMP ASSAY; CLINICAL ASSESSMENT; CONCENTRATION RESPONSE; EATING DISORDER; ENZYME MECHANISM; ESCHERICHIA COLI; FOOD INTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NONHUMAN; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; AGONISTS; AMINO ACID SEQUENCE; ANIMAL; HEK293 CELL LINE; MOUSE; SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HEAT-SHOCK PROTEINS; HEK293 CELLS; HUMANS; LIGANDS; MICE; PEPTIDE FRAGMENTS; RECEPTOR, MELANOCORTIN, TYPE 1;

EID: 84945898229     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.09.046     Document Type: Article

References (38)

1. R.C. Haynes Jr. J. Biol. Chem. 233 1958 1220
2. V. Chhajlani, and J.E. Wikberg FEBS Lett. 309 1992 417
3. K.G. Mountjoy, L.S. Robbins, M.T. Mortrud, and R.D. Cone Science 257 1992 1248
4. A.A. Butler, R.A. Kesterson, K. Khong, M.J. Cullen, M.A. Pelleymounter, J. Dekoning, M. Baetscher, and R.D. Cone Endocrinology 141 2000 3518
5. A.S. Chen, D.J. Marsh, M.E. Trumbauer, E.G. Frazier, X.M. Guan, H. Yu, C.I. Rosenblum, A. Vongs, Y. Feng, L.H. Cao, J.M. Metzger, A.M. Strack, R.E. Camacho, T.N. Mellin, C.N. Nunes, W. Min, J. Fisher, S. Gopal-Truter, D.E. MacIntyre, H.Y. Chen, and L.H.T. Van der Ploeg Nat. Genet. 26 2000 97
6. W. Fan, B.A. Boston, R.A. Kesterson, V.J. Hruby, and R.D. Cone Nature 385 1997 165
7. I. Gantz, Y. Konda, T. Tashiro, Y. Shimoto, H. Miwa, G. Munzert, S.J. Watson, J. DelValle, and T. Yamada J. Biol. Chem. 268 1993 8246
8. I. Gantz, H. Miwa, Y. Konda, Y. Shimoto, T. Tashiro, S.J. Watson, J. DelValle, and T. Yamada J. Biol. Chem. 268 1993 15174
9. D. Huszar, C.A. Lynch, V. Fairchild-Huntress, J.H. Dunmore, Q. Fang, L.R. Berkemeier, W. Gu, R.A. Kesterson, B.A. Boston, R.D. Cone, F.J. Smith, L.A. Campfield, P. Burn, and F. Lee Cell 88 1997 131
10. L. Roselli-Rehfuss, K.G. Mountjoy, L.S. Robbins, M.T. Mortrud, M.J. Low, J.B. Tatro, M.L. Entwistle, R.B. Simerly, and R.D. Cone Proc. Natl. Acad. Sci. U.S.A. 90 1993 8856
11. I. Gantz, Y. Shimoto, Y. Konda, H. Miwa, C.J. Dickinson, and T. Yamada Biochem. Biophys. Res. Commun. 200 1994 1214
12. N. Griffon, V. Mignon, P. Facchinetti, J. Diaz, J.C. Schwartz, and P. Sokoloff Biochem. Biophys. Res. Commun. 200 1994 1007
13. W. Chen, M.A. Kelly, X. Opitz-Araya, R.E. Thomas, M.J. Low, and R.D. Cone Cell 91 1997 789
14. S. Nakanishi, A. Inoue, T. Kita, M. Nakamura, A.C. Chang, S.N. Cohen, and S. Numa Nature 278 1979 423
15. S.G. Blanchard, C.O. Harris, O.R. Ittoop, J.S. Nichols, D.J. Parks, A.T. Truesdale, and W.O. Wilkison Biochemistry 34 1995 10406
16. T.M. Fong, C. Mao, T. MacNeil, R. Kalyani, T. Smith, D. Weinberg, M.R. Tota, and L.H.T. VanderPloeg Biochem. Biophys. Res. Commun. 237 1997 629
17. M.M. Ollmann, B.D. Wilson, Y.K. Yang, J.A. Kerns, Y.R. Chen, I. Gantz, and G.S. Barsh Science 278 1997 135
18. S.I. Candille, C.B. Kaelin, B.M. Cattanach, Y. Bin, D.A. Thompson, M.A. Nix, J.A. Kerns, S.M. Schmutz, G.L. Millhauser, and G.S. Barsh Science 318 2007 1418
19. V.B. Swope, J.A. Jameson, K.L. McFarland, D.M. Supp, W.E. Miller, D.W. McGraw, M.A. Patel, M.A. Nix, G.L. Millhauser, G.F. Babcock, and Z.A. Abdel-Malek J. Invest. Dermatol. 132 2012 2255
20. K.A. Beaumont, D.J. Smit, Y.Y. Liu, E. Chai, M.P. Patel, G.L. Millhauser, J.J. Smith, P.F. Alewood, and R.A. Sturm Pigment Cell Melanoma Res. 25 2012 370
21. M.A. Nix, C.B. Kaelin, T. Ta, A. Weis, G.J. Morton, G.S. Barsh, and G.L. Millhauser Chem. Biol. 20 2013 784
22. B.G. Irani, Z.M. Xiang, H.N. Yarandi, J.R. Holder, M.C. Moore, R.M. Bauzo, B. Proneth, A.M. Shaw, W.J. Millard, J.B. Chambers, S.C. Benoit, D.J. Clegg, and C. Haskell-Luevano Eur. J. Pharmacol. 660 2011 80
23. J.R. Greenfield, J.W. Miller, J.M. Keogh, E. Henning, J.H. Satterwhite, G.S. Cameron, B. Astruc, J.P. Mayer, S. Brage, T.C. See, D.J. Lomas, S. O'Rahilly, and I.S.N. Farooqi Engl. J. Med. 360 2009 44
24. R. Poggioli, A.V. Vergoni, and A. Bertolini Peptides 7 1986 843
25. S.O. Fetissov, J. Hallman, L. Oreland, B. Af Klinteberg, E. Grenback, A.L. Hulting, and T. Hokfelt Proc. Natl. Acad. Sci. U.S.A. 99 2002 17155
26. S.O. Fetissov, J. Harro, M. Jaanisk, A. Jarv, I. Podar, J. Allik, I. Nilsson, P. Sakthivel, A.K. Lefvert, and T. Hokfelt Proc. Natl. Acad. Sci. U.S.A. 102 2005 14865
27. S.O. Fetissov S.H. Fatemi, Neuropsychiatric Disorders and Infection 2005 Taylor and Francis Oxfordshire 253 262
28. N. Tennoune, P. Chan, J. Breton, R. Legrand, Y.N. Chabane, K. Akkermann, A. Jarv, W. Ouelaa, K. Takagi, I. Ghouzali, M. Francois, N. Lucas, C. Bole-Feysot, M. Pestel-Caron, J.C. do Rego, D. Vaudry, J. Harro, E. De, P. Dechelotte, and S.O. Fetissov Transl. Psychiatry 4 2014 e458
29. V.J. Hruby, B.C. Wilkes, M.E. Hadley, F. Alobeidi, T.K. Sawyer, D.J. Staples, A.E. Devaux, O. Dym, A.M.D. Castrucci, M.F. Hintz, J.P. Riehm, and K.R. Rao J. Med. Chem. 30 1987 2126
30. K.M. Woo, K.I. Kim, A.L. Goldberg, D.B. Ha, and C.H. Chung J. Biol. Chem. 267 1992 20429
31. L.A. Carpino, and G.Y. Han J. Am. Chem. Soc. 92 1970 5748
32. A. Singh, S. Tala, V. Flores, K. Freeman, and C. Haskell-Luevano ACS Med. Chem. Lett. 6 2015 568
33. L. Elster, C. Elling, and A. Heding J. Biomol. Screen. 12 2007 41
34. H.O. Schild Br. J. Pharmacol. Chemother. 2 1947 189
35. A.M.L. Castrucci, M.E. Hadley, T.K. Sawyer, B.C. Wilkes, F. Alobeidi, D.J. Staples, A.E. Devaux, O. Dym, M.F. Hintz, J.P. Riehm, K.R. Rao, and V.J. Hruby Gen. Comp. Endocrinol. 73 1989 157
36. C. Haskell-Luevano, J.R. Holder, E.K. Monck, and R.M. Bauzo J. Med. Chem. 44 2001 2247
37. C. Haskell-Luevano, T.K. Sawyer, S. Hendrata, C. North, L. Panahinia, M. Stum, D.J. Staples, A.M.D. Castrucci, M.E. Hadley, and V.J. Hruby Peptides 17 1996 995
38. U.G. Sahm, G.W.J. Olivier, S.K. Branch, S.H. Moss, and C.W. Pouton Peptides 15 1994 1297