AT1 receptor antagonism before ischemia prevents the transition of acute kidney injury to chronic kidney disease

Kidney International

Volumn 89, Issue 2, 2016, Pages 363-373

  Rodríguez Romo, Roxana ^a,b   Benítez, Kenia ^a,b   Barrera Chimal, Jonatan ^a,b   Pérez Villalva, Rosalba ^a,b   Gómez, Arturo ^a,b   Aguilar León, Diana ^b   Rangel Santiago, Jesús F ^c   Huerta, Sara ^c   Gamba, Gerardo ^a,b   Uribe, Norma ^b   Bobadilla, Norma A ^a,b  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^c HOSPITAL INFANTIL DE MÉXICO FEDERICO GÓMEZ   (Mexico)

Author keywords

glomerular hypertrophy; HIF 1 ; inflammation; proximal tubule; renal fibrosis; renal hypoperfusion; VEGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BIOLOGICAL MARKER; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LOSARTAN; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; EPITHELIUM CELL; INFLAMMATION; ISCHEMIA; KIDNEY BLOOD FLOW; KIDNEY INJURY; KIDNEY PERFUSION; KIDNEY TUBULE DAMAGE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ACUTE KIDNEY INJURY; ANIMAL; COMPLICATION; DRUG EFFECTS; KIDNEY; PRECLINICAL STUDY; RENAL INSUFFICIENCY, CHRONIC; REPERFUSION INJURY; VASCULARIZATION; WISTAR RAT;

ACUTE KIDNEY INJURY; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; DRUG EVALUATION, PRECLINICAL; KIDNEY; LOSARTAN; MALE; RATS, WISTAR; RENAL INSUFFICIENCY, CHRONIC; REPERFUSION INJURY;

EID: 84945561517     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2015.320     Document Type: Article

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