Erchen Decoction Prevents High-Fat Diet Induced Metabolic Disorders in C57BL/6 Mice

Evidence-based Complementary and Alternative Medicine

Volumn 2015, Issue , 2015, Pages

  Gao, Bi Zhen ^a   Chen, Ji Cheng ^b   Liao, Ling Hong ^a   Xu, Jia Qi ^a   Lin, Xiao Feng ^a   Ding, Shan Shan ^a  

^a FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Department of Endocrinology   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CDKAL1 PROTEIN; ERCHEN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PLANT MEDICINAL PRODUCT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ABDOMINAL CIRCUMFERENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; C57BL 6 MOUSE; CHINESE MEDICINE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; GLUCOSE TOLERANCE; INSULIN RELEASE; LIPID BLOOD LEVEL; LIPID DIET; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; TAIL VEIN; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84945551290     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2015/501272     Document Type: Article

References (36)

1. Q. Fu, "Clinical research on senile hypertension combined treatment of traditional Chinese and western medicine," China Journal of Traditional Chinese Medicine and Pharmacy, vol. 28, no. 9, pp. 2802-2803, 2013.
2. H. Z. Chen, G. M. Wei, Y. H. Dong et al., "Effects of Shenlin Baizu San and Erchen decoction and acupuncture on insulin resistance in type 2 diabetesmellitus," Clinical Journal of Chinese Medicine, vol. 6, no. 19, pp. 1-3, 2014.
3. F. T. Gao and S. S. Liu, "Clinical observation on Erchen decoction for the treatment of hyperlipidemia," Guide of China Medicine, vol. 11, no. 5, pp. 287-288, 2013.
4. T. Y. Luo, "Experience of Huangqi Jianzhong decoction and Erchen decoction in treating hyperlipidaemia," Journal of Practical Traditional Chinese Internal Medicine, vol. 28, no. 5, pp. 128-129, 2014.
5. H. P. Xiong, C. D. Li, B. Z. Gao, and H. Gan, "Study on relationship of pathology of phlegm syndrome of TCMwith blood sugar, insulin and insulin resistance in metabolic syndrome," China Journal of Traditional Chinese Medicine and Pharmacy, vol. 25, no. 5, pp. 763-765, 2010.
6. H. P. Xiong, C. D. Li, B. Z. Gao et al., "TCM risk factors of metabolic syndrome," China Journal of Traditional Chinese Medicine and Pharmacy, vol. 25, no. 11, pp. 1858-1859, 2010.
7. F.M. Pan and Z. Gui, "Clinical observation of Erchen decoction on treatment of 42 cases in nonalcoholic fatty liver disease," Journal of Yangtze University (Natural Science Edition)Medicine V, vol. 7, no. 4, pp. 13-14, 2010.
8. X. P. Hong, "Clinical observation of Erchen decoction on treatment of 60 cases in metabolic syndrome," Zhejiang Journal of Traditional Chinese Medicine, vol. 46, no. 5, article 343, 2011.
9. S. S. Ding, J. Kang, L. Y. Zhang et al., "Effect of Erchen decoction on blood fat and insulin resistance in rats fed a high-fat diet," Medical Innovation of China, vol. 11, no. 15, pp. 22-24, 2014.
10. X. J. Xie, J. Xu, Y. M. Li et al., "Effects of the Chinese medicine, modified Erchen decoction, on the lipid metabolism and hepatocyte morphology in ApoE-/- mice," Chinese Journal of Comparative Medicine, vol. 25, no. 4, pp. 44-47, 2015.
11. Z. H. Wang, X.M. Ji, Z. C. Wu et al., "Therapeutic effect ofCangbai Erchen decoction on aorta ICAM1 in metabolic syndrome rats," Chinese Archives of Traditional Chinese Medicine, vol. 31, no. 6, pp. 1243-1245, 2013.
12. S. Arragain, S. K. Handelman, F. Forouhar et al., "Identification of eukaryotic and prokaryotic methylthiotransferase for biosynthesis of 2-methylthio-N6-threonylcarbamoyladenosine in tRNA, "The Journal of Biological Chemistry, vol. 285, no. 37, pp. 28425-28433, 2010.
13. F.-Y. Wei, T. Suzuki, S. Watanabe et al., "Deficit of tRNALys modification by Cdkal1 causes the development of type 2 diabetes in mice," The Journal of Clinical Investigation, vol. 121, no. 9, pp. 3598-3608, 2011.
14. C. X. Chen, Pharmacology of Traditional Chinese Medicine, Shanghai Scientific and Technical Publishers, Shanghai, China, 2006.
15. K. J. Livak and T. D. Schmittgen, "Analysis of relative gene expression data using real-time quantitative PCRand the 2 -δδCT method," Methods, vol. 25, no. 4, pp. 402-408, 2001.
16. T. Y. Wu, B. Z. Gao, S. Lin et al., "Impacts of different herbal formulas on blood lipid in insulin resistance model rats," World Journal of Integrated Traditional and Western Medicine, vol. 4, no. 7, pp. 470-472, 2009.
17. S. Ding, J. Kang, L. Y. Zhang et al., "Effect of Erchen decoction on insulin resistance and related gene expression in rats fed a high-fat diet," Guangming Journal of Chinese Medicine, vol. 29, no. 9, pp. 1833-1836, 1833.
18. S. S. Ding, L. Y. Zhang, J. Kang et al., "Effect of Erchen decoction on lipid metabolism and Caveolin-1 expression in rats fed a high-fat diet," LishizhenMedicine and MateriaMedica Research, vol. 25, no. 9, pp. 2060-2062, 2014.
19. Z. H. Wang and Z. C. Wu, "Effect of Cangbai Erchen decoction on the expression of NF-κb in metabolic syndrome rats," Shandong Journal of Traditional Chinese Medicine, vol. 31, no. 8, pp. 594-596, 2012.
20. H. Y. Wang, Q. Yang, C. J. Liao et al., "Effect of Erchen decoction and Taohong Siwu decoction on nonalcoholic fatty liver disease rats," Journal of Guangzhou University of Traditional Chinese Medicine, vol. 30, no. 5, pp. 713-717, 2013.
21. E. Kim, "Insulin resistance at the crossroads of metabolic syndrome: systemic analysis using microarrays," Biotechnology Journal, vol. 5, no. 9, pp. 919-929, 2010.
22. S. Mottillo, K. B. Filion, J. Genest et al., "The metabolic syndrome and cardiovascular risk: a systematic review and meta-analysis," Journal of the American College of Cardiology, vol. 56, no. 14, pp. 1113-1132, 2010.
23. F.-Y. Wei and K. Tomizawa, "Functional loss of Cdkal1, a novel tRNA modification enzyme, causes the development of type 2 diabetes," Endocrine Journal, vol. 58, no. 10, pp. 819-825, 2011.
24. A. S. Dimas, V. Lagou, A. Barker et al., "Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity," Diabetes, vol. 63, no. 6, pp. 2158-2171, 2014.
25. M. Ohara-Imaizumi, M. Yoshida, K. Aoyagi et al., "Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis," PLoS ONE, vol. 5, no. 12, Article IDe15553, 2010.
26. L.M. 'THart, A. M. Simonis-Bik, G. Nijpels et al., "Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps," Diabetes, vol. 59, no. 1, pp. 287-292, 2010.
27. T. Okamura, R. Yanobu-Takanashi, F. Takeuchi et al., "Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetes," PLoS ONE, vol. 7, no. 11, Article ID e49055, 2012.
28. H. Ryoo, J. Woo, Y. Kim, and C. Lee, "Heterogeneity of genetic associations of CDKAL1 and HHEX with susceptibility of type 2 diabetes mellitus by gender," European Journal of Human Genetics, vol. 19, no. 6, pp. 672-675, 2011.
29. F. Peng, D. Hu, C. Gu et al., "The relationship between five widely-evaluated variants in CDKN2A/B and CDKAL1 genes and the risk of type 2 diabetes: a meta-analysis," Gene, vol. 531, no. 2, pp. 435-443, 2013.
30. Y. Mansoori, A. Daraei, M. Naghizadeh, and R. Salehi, "Significance of a common variant in the CDKAL1 gene with susceptibility to type 2 diabetes mellitus in Iranian population," Advanced Biomedical Research, vol. 4, no. 1, pp. 45-51, 2015.
31. K. U. Jyothi and B. M. Reddy, "Gene-gene and geneenvironment interactions in the etiology of type 2 diabetes mellitus in the population ofHyderabad, India," Meta Gene, vol. 5, pp. 9-20, 2015.
32. S. Al-Sinani, N. Woodhouse, A. Al-Mamari et al., "Association of gene variants with susceptibility to type 2 diabetes among Omanis," World Journal of Diabetes, vol. 6, no. 2, pp. 358-366, 2015.
33. M. J. Groenewoud, J. M. Dekker, A. Fritsche et al., "Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps," Diabetologia, vol. 51, no. 9, pp. 1659-1663, 2008.
34. A. Stančáková, T. Kuulasmaa, J. Paananen et al., "Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5, 327 nondiabetic Finnish men," Diabetes, vol. 58, no. 9, pp. 2129-2136, 2009.
35. S.-M. Ruchat, C. E. Elks, R. J. F. Loos et al., "Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies," Acta Diabetologica, vol. 46, no. 3, pp. 217-226, 2009.
36. J. Mei, S. Liao, Y. Liu et al., "Association of variants in CDKN2A/2B and CDKAL1 genes with gestational insulin sensitivity and disposition in pregnant Han Chinese women," Journal of Diabetes Investigation, vol. 6, no. 3, pp. 295-301, 2015.