The causal role of IL-4 and IL-13 in schistosoma mansoni pulmonary hypertension

American Journal of Respiratory and Critical Care Medicine

Volumn 192, Issue 8, 2015, Pages 998-1008

  Kumar, Rahul ^a   Mickael, Claudia ^a   Chabon, Jacob ^a   Gebreab, Liya ^a   Rutebemberwa, Alleluiah ^a   Garcia, Alexandra Rodriguez ^a   Koyanagi, Daniel E ^a   Sanders, Linda ^a   Gandjeva, Aneta ^a   Kearns, Mark T ^b   Barthel, Lea ^b   Janssen, William J ^b   Mauad, Thais ^c   Bandeira, Angela ^d   Schmidt, Eric ^a   Tuder, Rubin M ^a   Graham, Brian B ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b DEPARTMENT OF MEDICINE   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

Pulmonary hypertension; Schistosomiasis; Th2 cells; Transforming growth factor

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 4; PROTEIN INHIBITOR OF ACTIVATED STAT; SMAD2 PROTEIN; SMAD3 PROTEIN; STAT6 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; CELL ADHESION MOLECULE; IL4R PROTEIN, HUMAN; INTERLEUKIN 4 RECEPTOR ALPHA; POSTN PROTEIN, HUMAN; RETNLB PROTEIN, HUMAN; SIGNAL PEPTIDE; SMAD2 PROTEIN, MOUSE; SMAD3 PROTEIN, MOUSE; STAT6 PROTEIN, HUMAN; STAT6 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CONNECTIVE TISSUE DISEASE; CONTACT SENSITIZATION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; EVIDENCE BASED PRACTICE; FLOW CYTOMETRY; HEART CATHETERIZATION; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE PRESSURE; HUMAN; HUMAN TISSUE; IN VIVO STUDY; LIVER DISEASE; LUNG PARENCHYMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; PULMONARY VASCULAR DISEASE; QUANTITATIVE ANALYSIS; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; VASCULAR REMODELING; WILD TYPE MOUSE; ANIMAL; C57BL MOUSE; COMPLICATION; GENETICS; HYPERTENSION, PULMONARY; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; PHOSPHORYLATION; SCHISTOSOMIASIS MANSONI; TH1 CELL; TH17 CELL;

ANIMALS; BONE MARROW TRANSPLANTATION; CELL ADHESION MOLECULES; HUMANS; HYPERTENSION, PULMONARY; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-13; INTERLEUKIN-4; INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SMAD2 PROTEIN; SMAD3 PROTEIN; STAT6 TRANSCRIPTION FACTOR; TH1 CELLS; TH17 CELLS; TRANSFORMING GROWTH FACTOR BETA; VASCULAR REMODELING;

EID: 84945533803     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201410-1820OC     Document Type: Article

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