White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke

Experimental Neurology

Volumn 272, Issue , 2015, Pages 109-119

  Suenaga, Jun ^a   Hu, Xiaoming ^a,b,d   Pu, Hongjian ^a,b   Shi, Yejie ^a,d   Hassan, Sulaiman Habib ^a   Xu, Mingyue ^b   Leak, Rehana K ^c   Stetler, R Anne ^a,d   Gao, Yanqin ^b   Chen, Jun ^a,b,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b FUDAN UNIVERSITY   (China)

^c DUQUESNE UNIVERSITY   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Aging; Cerebral blood perfusion; Distal middle cerebral artery occlusion (dMCAO); Microglia

Indexed keywords

CD16 ANTIGEN; CD32 ANTIGEN; MYELIN BASIC PROTEIN; LEUKOCYTE ANTIGEN;

ADULT; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION SIZE; CAROTID ARTERY OBSTRUCTION; CELL MEMBRANE DEPOLARIZATION; CEREBROVASCULAR ACCIDENT; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; MACROPHAGE; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MORRIS WATER MAZE TEST; MORTALITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ROTAROD TEST; SENSORIMOTOR CORTEX; WHITE MATTER INJURY; YOUNG ADULT; ANIMAL; BRAIN CIRCULATION; BRAIN INFARCTION; C57BL MOUSE; CELL COUNT; CELL POLARITY; COMPLICATION; DISEASE MODEL; LEUKOENCEPHALOPATHIES; MAZE TEST; METABOLISM; MOTOR ACTIVITY; MUSCLE STRENGTH; NERVOUS SYSTEM DISEASES; PHYSIOLOGY; TIME FACTOR;

AGING; ANIMALS; ANTIGENS, CD; BRAIN INFARCTION; CELL COUNT; CELL POLARITY; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; LEUKOENCEPHALOPATHIES; MACROPHAGES; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICROGLIA; MOTOR ACTIVITY; MUSCLE STRENGTH; NERVOUS SYSTEM DISEASES; STROKE; TIME FACTORS;

EID: 84945479010     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2015.03.021     Document Type: Article

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