Bryostatin improves survival and reduces ischemic brain injury in aged rats after acute ischemic stroke

Stroke

Volumn 44, Issue 12, 2013, Pages 3490-3497

  Tan, Zhenjun ^a   Turner, Ryan C ^a   Leon, Rachel L ^a   Li, Xinlan ^a   Hongpaisan, Jarin ^a   Zheng, Wen ^a   Logsdon, Aric F ^b   Naser, Zachary J ^a   Alkon, Daniel L ^a   Rosen, Charles L ^a   Huber, Jason D ^b  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Aging; Blood brain barrier; Infarction; Protein kinase C; Tissue plasminogen activator

Indexed keywords

BRYOSTATIN; CD31 ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; PROTEIN KINASE C ALPHA; PROTEIN KINASE C EPSILON; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ATROPHY; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; FUNCTIONAL ASSESSMENT; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAZE TEST; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SURVIVAL;

AGING; BLOOD-BRAIN BARRIER; INFARCTION; PROTEIN KINASE C; TISSUE PLASMINOGEN ACTIVATOR;

ANIMALS; APOPTOSIS; ASTROCYTES; BRAIN; BRAIN ISCHEMIA; BRYOSTATINS; DISEASE MODELS, ANIMAL; FEMALE; GLIOSIS; NEURONS; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; STROKE; SURVIVAL RATE;

EID: 84889247700     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.002411     Document Type: Article

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