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Volumn 119-120, Issue , 2014, Pages 60-84

Neurobiology of microglial action in CNS injuries: Receptor-mediated signaling mechanisms and functional roles

Author keywords

Central nervous system injuries; Microglia; Receptor

Indexed keywords

ADENOSINE A2A RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR; ADVANCED GLYCATION END PRODUCT RECEPTOR; CD200 RECEPTOR; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CX3CR1; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR4; FC RECEPTOR; FRACTALKINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN SUPERFAMILY; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PATTERN RECOGNITION RECEPTOR; PHOSPHATIDYLSERINE; PURINERGIC P2 RECEPTOR; PURINERGIC P2X RECEPTOR; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y2 RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 3; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; CHEMOKINE RECEPTOR; PHOSPHATIDYLSERINE RECEPTOR; PURINERGIC RECEPTOR;

EID: 84905373642     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2014.06.002     Document Type: Review
Times cited : (120)

References (353)
  • 2
    • 10044230497 scopus 로고    scopus 로고
    • S100B-stimulated NO production by BV-2 microglia is independent of RAGE transducing activity but dependent on RAGE extracellular domain
    • Adami C., Bianchi R., Pula G., Donato R. S100B-stimulated NO production by BV-2 microglia is independent of RAGE transducing activity but dependent on RAGE extracellular domain. Biochim. Biophys. Acta 2004, 1742:169-177.
    • (2004) Biochim. Biophys. Acta , vol.1742 , pp. 169-177
    • Adami, C.1    Bianchi, R.2    Pula, G.3    Donato, R.4
  • 3
    • 3543053363 scopus 로고    scopus 로고
    • Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
    • Albert M.L., Pearce S.F., Francisco L.M., Sauter B., Roy P., Silverstein R.L., Bhardwaj N. Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes. J. Exp. Med. 1998, 188:1359-1368.
    • (1998) J. Exp. Med. , vol.188 , pp. 1359-1368
    • Albert, M.L.1    Pearce, S.F.2    Francisco, L.M.3    Sauter, B.4    Roy, P.5    Silverstein, R.L.6    Bhardwaj, N.7
  • 4
    • 0242416171 scopus 로고    scopus 로고
    • A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation
    • Angulo E., Casado V., Mallol J., Canela E.I., Vinals F., Ferrer I., Lluis C., Franco R. A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation. Brain Pathol. 2003, 13:440-451.
    • (2003) Brain Pathol. , vol.13 , pp. 440-451
    • Angulo, E.1    Casado, V.2    Mallol, J.3    Canela, E.I.4    Vinals, F.5    Ferrer, I.6    Lluis, C.7    Franco, R.8
  • 5
    • 0029838164 scopus 로고    scopus 로고
    • Differential regulation of G-protein-mediated signaling by chemokine receptors
    • Arai H., Charo I.F. Differential regulation of G-protein-mediated signaling by chemokine receptors. J. Biol. Chem. 1996, 271:21814-21819.
    • (1996) J. Biol. Chem. , vol.271 , pp. 21814-21819
    • Arai, H.1    Charo, I.F.2
  • 7
    • 0033231896 scopus 로고    scopus 로고
    • Chemokines in the CNS: plurifunctional mediators in diverse states
    • Asensio V.C., Campbell I.L. Chemokines in the CNS: plurifunctional mediators in diverse states. Trends Neurosci. 1999, 22:504-512.
    • (1999) Trends Neurosci. , vol.22 , pp. 504-512
    • Asensio, V.C.1    Campbell, I.L.2
  • 8
    • 0041319041 scopus 로고    scopus 로고
    • Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS
    • Babcock A.A., Kuziel W.A., Rivest S., Owens T. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J. Neurosci. 2003, 23:7922-7930.
    • (2003) J. Neurosci. , vol.23 , pp. 7922-7930
    • Babcock, A.A.1    Kuziel, W.A.2    Rivest, S.3    Owens, T.4
  • 9
    • 0037387147 scopus 로고    scopus 로고
    • A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation
    • Bamberger M.E., Harris M.E., McDonald D.R., Husemann J., Landreth G.E. A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation. J. Neurosci. 2003, 23:2665-2674.
    • (2003) J. Neurosci. , vol.23 , pp. 2665-2674
    • Bamberger, M.E.1    Harris, M.E.2    McDonald, D.R.3    Husemann, J.4    Landreth, G.E.5
  • 10
    • 0036435123 scopus 로고    scopus 로고
    • Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons
    • Banisadr G., Fontanges P., Haour F., Kitabgi P., Rostene W., Melik Parsadaniantz S. Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons. Eur. J. Neurosci. 2002, 16:1661-1671.
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 1661-1671
    • Banisadr, G.1    Fontanges, P.2    Haour, F.3    Kitabgi, P.4    Rostene, W.5    Melik Parsadaniantz, S.6
  • 12
    • 78650058880 scopus 로고    scopus 로고
    • A role for spleen monocytes in post-ischemic brain inflammation and injury
    • Bao Y., Kim E., Bhosle S., Mehta H., Cho S. A role for spleen monocytes in post-ischemic brain inflammation and injury. J. Neuroinflammation 2010, 7:92.
    • (2010) J. Neuroinflammation , vol.7 , pp. 92
    • Bao, Y.1    Kim, E.2    Bhosle, S.3    Mehta, H.4    Cho, S.5
  • 14
    • 0033512004 scopus 로고    scopus 로고
    • Inflammatory mediators and stroke: new opportunities for novel therapeutics
    • Barone F.C., Feuerstein G.Z. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J. Cereb. Blood Flow Metab. 1999, 19:819-834.
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , pp. 819-834
    • Barone, F.C.1    Feuerstein, G.Z.2
  • 15
    • 33746256913 scopus 로고    scopus 로고
    • You say ITAM and I say ITIM, let's call the whole thing off: the ambiguity of immunoreceptor signalling
    • Barrow A.D., Trowsdale J. You say ITAM and I say ITIM, let's call the whole thing off: the ambiguity of immunoreceptor signalling. Eur. J. Immunol. 2006, 36:1646-1653.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 1646-1653
    • Barrow, A.D.1    Trowsdale, J.2
  • 16
    • 80054016170 scopus 로고    scopus 로고
    • Association of clinical and aetiologic subtype of acute ischaemic stroke with inflammation, oxidative stress and vascular function: a cross-sectional observational study
    • Beer C., Blacker D., Hankey G.J., Puddey I.B. Association of clinical and aetiologic subtype of acute ischaemic stroke with inflammation, oxidative stress and vascular function: a cross-sectional observational study. Med. Sci. Monit. 2011, 17:CR467-CR473.
    • (2011) Med. Sci. Monit. , vol.17
    • Beer, C.1    Blacker, D.2    Hankey, G.J.3    Puddey, I.B.4
  • 17
    • 84864487226 scopus 로고    scopus 로고
    • P2X4R+ microglia drive neuropathic pain
    • Beggs S., Trang T., Salter M.W. P2X4R+ microglia drive neuropathic pain. Nat. Neurosci. 2012, 15:1068-1073.
    • (2012) Nat. Neurosci. , vol.15 , pp. 1068-1073
    • Beggs, S.1    Trang, T.2    Salter, M.W.3
  • 20
    • 33845885123 scopus 로고    scopus 로고
    • S100B binding to RAGE in microglia stimulates COX-2 expression
    • Bianchi R., Adami C., Giambanco I., Donato R. S100B binding to RAGE in microglia stimulates COX-2 expression. J. Leukoc. Biol. 2007, 81:108-118.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 108-118
    • Bianchi, R.1    Adami, C.2    Giambanco, I.3    Donato, R.4
  • 21
    • 77049088494 scopus 로고    scopus 로고
    • S100B/RAGE-dependent activation of microglia via NF-kappaB and AP-1 co-regulation of COX-2 expression by S100B, IL-1beta and TNF-alpha
    • Bianchi R., Giambanco I., Donato R. S100B/RAGE-dependent activation of microglia via NF-kappaB and AP-1 co-regulation of COX-2 expression by S100B, IL-1beta and TNF-alpha. Neurobiol. Aging 2010, 31:665-677.
    • (2010) Neurobiol. Aging , vol.31 , pp. 665-677
    • Bianchi, R.1    Giambanco, I.2    Donato, R.3
  • 22
    • 79953214581 scopus 로고    scopus 로고
    • S100B protein stimulates microglia migration via RAGE-dependent up-regulation of chemokine expression and release
    • Bianchi R., Kastrisianaki E., Giambanco I., Donato R. S100B protein stimulates microglia migration via RAGE-dependent up-regulation of chemokine expression and release. J. Biol. Chem. 2011, 286:7214-7226.
    • (2011) J. Biol. Chem. , vol.286 , pp. 7214-7226
    • Bianchi, R.1    Kastrisianaki, E.2    Giambanco, I.3    Donato, R.4
  • 27
    • 0035870604 scopus 로고    scopus 로고
    • Ischemia-induced neuronal expression of the microglia attracting chemokine Secondary Lymphoid-tissue Chemokine (SLC)
    • Biber K., Sauter A., Brouwer N., Copray S.C., Boddeke H.W. Ischemia-induced neuronal expression of the microglia attracting chemokine Secondary Lymphoid-tissue Chemokine (SLC). Glia 2001, 34:121-133.
    • (2001) Glia , vol.34 , pp. 121-133
    • Biber, K.1    Sauter, A.2    Brouwer, N.3    Copray, S.C.4    Boddeke, H.W.5
  • 30
    • 79952506823 scopus 로고    scopus 로고
    • Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination
    • Binder M.D., Xiao J., Kemper D., Ma G.Z., Murray S.S., Kilpatrick T.J. Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination. PLoS ONE 2011, 6:e17727.
    • (2011) PLoS ONE , vol.6
    • Binder, M.D.1    Xiao, J.2    Kemper, D.3    Ma, G.Z.4    Murray, S.S.5    Kilpatrick, T.J.6
  • 31
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
    • Block M.L., Zecca L., Hong J.S. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat. Rev. Neurosci. 2007, 8:57-69.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.S.3
  • 33
  • 34
    • 0037404152 scopus 로고    scopus 로고
    • Macrophage recognition of externalized phosphatidylserine and phagocytosis of apoptotic Jurkat cells - existence of a threshold
    • Borisenko G.G., Matsura T., Liu S.X., Tyurin V.A., Jianfei J., Serinkan F.B., Kagan V.E. Macrophage recognition of externalized phosphatidylserine and phagocytosis of apoptotic Jurkat cells - existence of a threshold. Arch. Biochem. Biophys. 2003, 413:41-52.
    • (2003) Arch. Biochem. Biophys. , vol.413 , pp. 41-52
    • Borisenko, G.G.1    Matsura, T.2    Liu, S.X.3    Tyurin, V.A.4    Jianfei, J.5    Serinkan, F.B.6    Kagan, V.E.7
  • 35
    • 0034657890 scopus 로고    scopus 로고
    • Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes
    • Bouchon A., Dietrich J., Colonna M. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J. Immunol. 2000, 164:4991-4995.
    • (2000) J. Immunol. , vol.164 , pp. 4991-4995
    • Bouchon, A.1    Dietrich, J.2    Colonna, M.3
  • 37
    • 0036841178 scopus 로고    scopus 로고
    • Broad expression of Toll-like receptors in the human central nervous system
    • Bsibsi M., Ravid R., Gveric D., van Noort J.M. Broad expression of Toll-like receptors in the human central nervous system. J. Neuropathol. Exp. Neurol. 2002, 61:1013-1021.
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 1013-1021
    • Bsibsi, M.1    Ravid, R.2    Gveric, D.3    van Noort, J.M.4
  • 38
    • 0029671045 scopus 로고    scopus 로고
    • An antagonist-insensitive P2X receptor expressed in epithelia and brain
    • Buell G., Lewis C., Collo G., North R.A., Surprenant A. An antagonist-insensitive P2X receptor expressed in epithelia and brain. EMBO J. 1996, 15:55-62.
    • (1996) EMBO J. , vol.15 , pp. 55-62
    • Buell, G.1    Lewis, C.2    Collo, G.3    North, R.A.4    Surprenant, A.5
  • 40
    • 77950896927 scopus 로고    scopus 로고
    • Interactions between TLR7 and TLR9 agonists and receptors regulate innate immune responses by astrocytes and microglia
    • Butchi N.B., Du M., Peterson K.E. Interactions between TLR7 and TLR9 agonists and receptors regulate innate immune responses by astrocytes and microglia. Glia 2010, 58:650-664.
    • (2010) Glia , vol.58 , pp. 650-664
    • Butchi, N.B.1    Du, M.2    Peterson, K.E.3
  • 41
    • 79953205512 scopus 로고    scopus 로고
    • ATP: a ubiquitous gliotransmitter integrating neuron-glial networks
    • Butt A.M. ATP: a ubiquitous gliotransmitter integrating neuron-glial networks. Semin. Cell Dev. Biol. 2011, 22:205-213.
    • (2011) Semin. Cell Dev. Biol. , vol.22 , pp. 205-213
    • Butt, A.M.1
  • 43
    • 23044447142 scopus 로고    scopus 로고
    • Migration of perilesional microglia after focal brain injury and modulation by CC chemokine receptor 5: an in situ time-lapse confocal imaging study
    • Carbonell W.S., Murase S., Horwitz A.F., Mandell J.W. Migration of perilesional microglia after focal brain injury and modulation by CC chemokine receptor 5: an in situ time-lapse confocal imaging study. J. Neurosci. 2005, 25:7040-7047.
    • (2005) J. Neurosci. , vol.25 , pp. 7040-7047
    • Carbonell, W.S.1    Murase, S.2    Horwitz, A.F.3    Mandell, J.W.4
  • 46
    • 34247545017 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke
    • Caso J.R., Pradillo J.M., Hurtado O., Lorenzo P., Moro M.A., Lizasoain I. Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation 2007, 115:1599-1608.
    • (2007) Circulation , vol.115 , pp. 1599-1608
    • Caso, J.R.1    Pradillo, J.M.2    Hurtado, O.3    Lorenzo, P.4    Moro, M.A.5    Lizasoain, I.6
  • 48
    • 0028316908 scopus 로고
    • Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails
    • Charo I.F., Myers S.J., Herman A., Franci C., Connolly A.J., Coughlin S.R. Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:2752-2756.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 2752-2756
    • Charo, I.F.1    Myers, S.J.2    Herman, A.3    Franci, C.4    Connolly, A.J.5    Coughlin, S.R.6
  • 49
    • 0035887925 scopus 로고    scopus 로고
    • Lack of CCR2 results in increased mortality and impaired leukocyte activation and trafficking following infection of the central nervous system with a neurotropic coronavirus
    • Chen B.P., Kuziel W.A., Lane T.E. Lack of CCR2 results in increased mortality and impaired leukocyte activation and trafficking following infection of the central nervous system with a neurotropic coronavirus. J. Immunol. 2001, 167:4585-4592.
    • (2001) J. Immunol. , vol.167 , pp. 4585-4592
    • Chen, B.P.1    Kuziel, W.A.2    Lane, T.E.3
  • 50
    • 34948895675 scopus 로고    scopus 로고
    • Overstaying their welcome: defective CX3CR1 microglia eyed in macular degeneration
    • Chen J., Connor K.M., Smith L.E. Overstaying their welcome: defective CX3CR1 microglia eyed in macular degeneration. J. Clin. Invest. 2007, 117:2758-2762.
    • (2007) J. Clin. Invest. , vol.117 , pp. 2758-2762
    • Chen, J.1    Connor, K.M.2    Smith, L.E.3
  • 52
    • 80052714655 scopus 로고    scopus 로고
    • CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease
    • Cho S.H., Sun B., Zhou Y., Kauppinen T.M., Halabisky B., Wes P., Ransohoff R.M., Gan L. CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. J. Biol. Chem. 2011, 286:32713-32722.
    • (2011) J. Biol. Chem. , vol.286 , pp. 32713-32722
    • Cho, S.H.1    Sun, B.2    Zhou, Y.3    Kauppinen, T.M.4    Halabisky, B.5    Wes, P.6    Ransohoff, R.M.7    Gan, L.8
  • 53
    • 80053271201 scopus 로고    scopus 로고
    • A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats
    • Choi I.Y., Lee J.C., Ju C., Hwang S., Cho G.S., Lee H.W., Choi W.J., Jeong L.S., Kim W.K. A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats. Am. J. Pathol. 2011, 179:2042-2052.
    • (2011) Am. J. Pathol. , vol.179 , pp. 2042-2052
    • Choi, I.Y.1    Lee, J.C.2    Ju, C.3    Hwang, S.4    Cho, G.S.5    Lee, H.W.6    Choi, W.J.7    Jeong, L.S.8    Kim, W.K.9
  • 54
    • 84859791412 scopus 로고    scopus 로고
    • Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus
    • Chu K., Yin B., Wang J., Peng G., Liang H., Xu Z., Du Y., Fang M., Xia Q., Luo B. Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus. J. Neuroinflammation 2012, 9:69.
    • (2012) J. Neuroinflammation , vol.9 , pp. 69
    • Chu, K.1    Yin, B.2    Wang, J.3    Peng, G.4    Liang, H.5    Xu, Z.6    Du, Y.7    Fang, M.8    Xia, Q.9    Luo, B.10
  • 55
    • 84864491878 scopus 로고    scopus 로고
    • Galectin-1 promotes lung cancer progression and chemoresistance by upregulating p38 MAPK, ERK, and cyclooxygenase-2
    • Chung L.Y., Tang S.J., Sun G.H., Chou T.Y., Yeh T.S., Yu S.L., Sun K.H. Galectin-1 promotes lung cancer progression and chemoresistance by upregulating p38 MAPK, ERK, and cyclooxygenase-2. Clin. Cancer Res. 2012, 18:4037-4047.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 4037-4047
    • Chung, L.Y.1    Tang, S.J.2    Sun, G.H.3    Chou, T.Y.4    Yeh, T.S.5    Yu, S.L.6    Sun, K.H.7
  • 56
    • 0346667110 scopus 로고    scopus 로고
    • Structure-function relationship between the human chemokine receptor CXCR3 and its ligands
    • Clark-Lewis I., Mattioli I., Gong J.H., Loetscher P. Structure-function relationship between the human chemokine receptor CXCR3 and its ligands. J. Biol. Chem. 2003, 278:289-295.
    • (2003) J. Biol. Chem. , vol.278 , pp. 289-295
    • Clark-Lewis, I.1    Mattioli, I.2    Gong, J.H.3    Loetscher, P.4
  • 58
    • 66149186748 scopus 로고    scopus 로고
    • The liberation of fractalkine in the dorsal horn requires microglial cathepsin S
    • Clark A.K., Yip P.K., Malcangio M. The liberation of fractalkine in the dorsal horn requires microglial cathepsin S. J. Neurosci. 2009, 29:6945-6954.
    • (2009) J. Neurosci. , vol.29 , pp. 6945-6954
    • Clark, A.K.1    Yip, P.K.2    Malcangio, M.3
  • 60
    • 0036141148 scopus 로고    scopus 로고
    • CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils
    • Coraci I.S., Husemann J., Berman J.W., Hulette C., Dufour J.H., Campanella G.K., Luster A.D., Silverstein S.C., El-Khoury J.B. CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils. Am. J. Pathol. 2002, 160:101-112.
    • (2002) Am. J. Pathol. , vol.160 , pp. 101-112
    • Coraci, I.S.1    Husemann, J.2    Berman, J.W.3    Hulette, C.4    Dufour, J.H.5    Campanella, G.K.6    Luster, A.D.7    Silverstein, S.C.8    El-Khoury, J.B.9
  • 63
    • 33645032431 scopus 로고    scopus 로고
    • Microglial expression of chemokine receptor CCR5 during rat forebrain development and after perinatal hypoxia-ischemia
    • Cowell R.M., Xu H., Parent J.M., Silverstein F.S. Microglial expression of chemokine receptor CCR5 during rat forebrain development and after perinatal hypoxia-ischemia. J. Neuroimmunol. 2006, 173:155-165.
    • (2006) J. Neuroimmunol. , vol.173 , pp. 155-165
    • Cowell, R.M.1    Xu, H.2    Parent, J.M.3    Silverstein, F.S.4
  • 64
    • 71049175666 scopus 로고    scopus 로고
    • Expression of P2 nucleotide receptors varies with age and sex in murine brain microglia
    • Crain J.M., Nikodemova M., Watters J.J. Expression of P2 nucleotide receptors varies with age and sex in murine brain microglia. J. Neuroinflammation 2009, 6:24.
    • (2009) J. Neuroinflammation , vol.6 , pp. 24
    • Crain, J.M.1    Nikodemova, M.2    Watters, J.J.3
  • 66
    • 0012296395 scopus 로고    scopus 로고
    • Selective gene expression in brain microglia mediated via adeno-associated virus type 2 and type 5 vectors
    • Cucchiarini M., Ren X.L., Perides G., Terwilliger E.F. Selective gene expression in brain microglia mediated via adeno-associated virus type 2 and type 5 vectors. Gene Ther. 2003, 10:657-667.
    • (2003) Gene Ther. , vol.10 , pp. 657-667
    • Cucchiarini, M.1    Ren, X.L.2    Perides, G.3    Terwilliger, E.F.4
  • 67
    • 60849135712 scopus 로고    scopus 로고
    • Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factoralpha signaling during peripheral organ inflammation
    • D'Mello C., Le T., Swain M.G. Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factoralpha signaling during peripheral organ inflammation. J. Neurosci. 2009, 29:2089-2102.
    • (2009) J. Neurosci. , vol.29 , pp. 2089-2102
    • D'Mello, C.1    Le, T.2    Swain, M.G.3
  • 68
    • 77953099826 scopus 로고    scopus 로고
    • Adenosine A2A receptors in both bone marrow cells and non-bone marrow cells contribute to traumatic brain injury
    • Dai S.S., Li W., An J.H., Wang H., Yang N., Chen X.Y., Zhao Y., Li P., Liu P., Chen J.F., Zhou Y.G. Adenosine A2A receptors in both bone marrow cells and non-bone marrow cells contribute to traumatic brain injury. J. Neurochem. 2010, 113:1536-1544.
    • (2010) J. Neurochem. , vol.113 , pp. 1536-1544
    • Dai, S.S.1    Li, W.2    An, J.H.3    Wang, H.4    Yang, N.5    Chen, X.Y.6    Zhao, Y.7    Li, P.8    Liu, P.9    Chen, J.F.10    Zhou, Y.G.11
  • 69
    • 0035511611 scopus 로고    scopus 로고
    • Ion-channel regulation by G proteins
    • Dascal N. Ion-channel regulation by G proteins. Trends Endocrinol. Metab. 2001, 12:391-398.
    • (2001) Trends Endocrinol. Metab. , vol.12 , pp. 391-398
    • Dascal, N.1
  • 71
    • 23844452985 scopus 로고    scopus 로고
    • Vesicle-mediated transport and release of CCL21 in endangered neurons: a possible explanation for microglia activation remote from a primary lesion
    • de Jong E.K., Dijkstra I.M., Hensens M., Brouwer N., van Amerongen M., Liem R.S., Boddeke H.W., Biber K. Vesicle-mediated transport and release of CCL21 in endangered neurons: a possible explanation for microglia activation remote from a primary lesion. J. Neurosci. 2005, 25:7548-7557.
    • (2005) J. Neurosci. , vol.25 , pp. 7548-7557
    • de Jong, E.K.1    Dijkstra, I.M.2    Hensens, M.3    Brouwer, N.4    van Amerongen, M.5    Liem, R.S.6    Boddeke, H.W.7    Biber, K.8
  • 72
    • 0036194904 scopus 로고    scopus 로고
    • Expression of phosphatidylserine receptor and down-regulation of pro-inflammatory molecule production by its natural ligand in rat microglial cultures
    • De S.R., Ajmone-Cat M.A., Nicolini A., Minghetti L. Expression of phosphatidylserine receptor and down-regulation of pro-inflammatory molecule production by its natural ligand in rat microglial cultures. J. Neuropathol. Exp. Neurol. 2002, 61:237-244.
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 237-244
    • De, S.R.1    Ajmone-Cat, M.A.2    Nicolini, A.3    Minghetti, L.4
  • 73
    • 52549109505 scopus 로고    scopus 로고
    • Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse
    • Denes A., Ferenczi S., Halasz J., Kornyei Z., Kovacs K.J. Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse. J. Cereb. Blood Flow Metab. 2008, 28:1707-1721.
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1707-1721
    • Denes, A.1    Ferenczi, S.2    Halasz, J.3    Kornyei, Z.4    Kovacs, K.J.5
  • 74
    • 65449143227 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 (MCP-1) produced via NF-kappaB signaling pathway mediates migration of amoeboid microglia in the periventricular white matter in hypoxic neonatal rats
    • Deng Y.Y., Lu J., Ling E.A., Kaur C. Monocyte chemoattractant protein-1 (MCP-1) produced via NF-kappaB signaling pathway mediates migration of amoeboid microglia in the periventricular white matter in hypoxic neonatal rats. Glia 2009, 57:604-621.
    • (2009) Glia , vol.57 , pp. 604-621
    • Deng, Y.Y.1    Lu, J.2    Ling, E.A.3    Kaur, C.4
  • 75
    • 84866252499 scopus 로고    scopus 로고
    • Fractalkine mediates communication between pathogenic proteins and microglia: implications of anti-inflammatory treatments in different stages of neurodegenerative diseases
    • Desforges N.M., Hebron M.L., Algarzae N.K., Lonskaya I., Moussa C.E. Fractalkine mediates communication between pathogenic proteins and microglia: implications of anti-inflammatory treatments in different stages of neurodegenerative diseases. Int. J. Alzheimers Dis. 2012, 2012:345472.
    • (2012) Int. J. Alzheimers Dis. , vol.2012 , pp. 345472
    • Desforges, N.M.1    Hebron, M.L.2    Algarzae, N.K.3    Lonskaya, I.4    Moussa, C.E.5
  • 76
    • 1342303483 scopus 로고    scopus 로고
    • Cutting edge: activity of human adult microglia in response to CC chemokine ligand 21
    • Dijkstra I.M., Hulshof S., van der Valk P., Boddeke H.W., Biber K. Cutting edge: activity of human adult microglia in response to CC chemokine ligand 21. J. Immunol. 2004, 172:2744-2747.
    • (2004) J. Immunol. , vol.172 , pp. 2744-2747
    • Dijkstra, I.M.1    Hulshof, S.2    van der Valk, P.3    Boddeke, H.W.4    Biber, K.5
  • 77
    • 34247874753 scopus 로고    scopus 로고
    • Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice
    • Dimitrijevic O.B., Stamatovic S.M., Keep R.F., Andjelkovic A.V. Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice. Stroke 2007, 38:1345-1353.
    • (2007) Stroke , vol.38 , pp. 1345-1353
    • Dimitrijevic, O.B.1    Stamatovic, S.M.2    Keep, R.F.3    Andjelkovic, A.V.4
  • 78
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: an integrated view
    • Dirnagl U., Iadecola C., Moskowitz M.A. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 1999, 22:391-397.
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 79
    • 79960122953 scopus 로고    scopus 로고
    • Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages
    • Donnelly D.J., Longbrake E.E., Shawler T.M., Kigerl K.A., Lai W., Tovar C.A., Ransohoff R.M., Popovich P.G. Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages. J. Neurosci. 2011, 31:9910-9922.
    • (2011) J. Neurosci. , vol.31 , pp. 9910-9922
    • Donnelly, D.J.1    Longbrake, E.E.2    Shawler, T.M.3    Kigerl, K.A.4    Lai, W.5    Tovar, C.A.6    Ransohoff, R.M.7    Popovich, P.G.8
  • 80
    • 0141755110 scopus 로고    scopus 로고
    • Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs)
    • Dukic-Stefanovic S., Gasic-Milenkovic J., Deuther-Conrad W., Munch G. Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs). J. Neurochem. 2003, 87:44-55.
    • (2003) J. Neurochem. , vol.87 , pp. 44-55
    • Dukic-Stefanovic, S.1    Gasic-Milenkovic, J.2    Deuther-Conrad, W.3    Munch, G.4
  • 83
    • 32544437823 scopus 로고    scopus 로고
    • CCL2/monocyte chemoattractant protein-1 mediates enhanced transmigration of human immunodeficiency virus (HIV)-infected leukocytes across the blood-brain barrier: a potential mechanism of HIV-CNS invasion and NeuroAIDS
    • Eugenin E.A., Osiecki K., Lopez L., Goldstein H., Calderon T.M., Berman J.W. CCL2/monocyte chemoattractant protein-1 mediates enhanced transmigration of human immunodeficiency virus (HIV)-infected leukocytes across the blood-brain barrier: a potential mechanism of HIV-CNS invasion and NeuroAIDS. J. Neurosci. 2006, 26:1098-1106.
    • (2006) J. Neurosci. , vol.26 , pp. 1098-1106
    • Eugenin, E.A.1    Osiecki, K.2    Lopez, L.3    Goldstein, H.4    Calderon, T.M.5    Berman, J.W.6
  • 86
    • 77951647591 scopus 로고    scopus 로고
    • RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
    • Fang F., Lue L.F., Yan S., Xu H., Luddy J.S., Chen D., Walker D.G., Stern D.M., Schmidt A.M., Chen J.X., Yan S.S. RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease. FASEB J. 2010, 24:1043-1055.
    • (2010) FASEB J. , vol.24 , pp. 1043-1055
    • Fang, F.1    Lue, L.F.2    Yan, S.3    Xu, H.4    Luddy, J.S.5    Chen, D.6    Walker, D.G.7    Stern, D.M.8    Schmidt, A.M.9    Chen, J.X.10    Yan, S.S.11
  • 90
    • 0031054641 scopus 로고    scopus 로고
    • Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin
    • Ferrari D., Chiozzi P., Falzoni S., Hanau S., Di Virgilio F. Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin. J. Exp. Med. 1997, 185:579-582.
    • (1997) J. Exp. Med. , vol.185 , pp. 579-582
    • Ferrari, D.1    Chiozzi, P.2    Falzoni, S.3    Hanau, S.4    Di Virgilio, F.5
  • 91
    • 0033051323 scopus 로고    scopus 로고
    • P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death
    • Ferrari D., Los M., Bauer M.K., Vandenabeele P., Wesselborg S., Schulze-Osthoff K. P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death. FEBS Lett. 1999, 447:71-75.
    • (1999) FEBS Lett. , vol.447 , pp. 71-75
    • Ferrari, D.1    Los, M.2    Bauer, M.K.3    Vandenabeele, P.4    Wesselborg, S.5    Schulze-Osthoff, K.6
  • 93
    • 0031425953 scopus 로고    scopus 로고
    • Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65
    • Ferrari D., Wesselborg S., Bauer M.K., Schulze-Osthoff K. Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65. J. Cell Biol. 1997, 139:1635-1643.
    • (1997) J. Cell Biol. , vol.139 , pp. 1635-1643
    • Ferrari, D.1    Wesselborg, S.2    Bauer, M.K.3    Schulze-Osthoff, K.4
  • 95
    • 0026748591 scopus 로고
    • A soluble form of Fc gamma RIII is present in human serum and other body fluids and is elevated at sites of inflammation
    • Fleit H.B., Kobasiuk C.D., Daly C., Furie R., Levy P.C., Webster R.O. A soluble form of Fc gamma RIII is present in human serum and other body fluids and is elevated at sites of inflammation. Blood 1992, 79:2721-2728.
    • (1992) Blood , vol.79 , pp. 2721-2728
    • Fleit, H.B.1    Kobasiuk, C.D.2    Daly, C.3    Furie, R.4    Levy, P.C.5    Webster, R.O.6
  • 96
    • 0037334295 scopus 로고    scopus 로고
    • Regulation of chemokine receptor expression in human microglia and astrocytes
    • Flynn G., Maru S., Loughlin J., Romero I.A., Male D. Regulation of chemokine receptor expression in human microglia and astrocytes. J. Neuroimmunol. 2003, 136:84-93.
    • (2003) J. Neuroimmunol. , vol.136 , pp. 84-93
    • Flynn, G.1    Maru, S.2    Loughlin, J.3    Romero, I.A.4    Male, D.5
  • 97
    • 0029005967 scopus 로고
    • Monocyte chemoattractant protein-3, but not monocyte chemoattractant protein-2, is a functional ligand of the human monocyte chemoattractant protein-1 receptor
    • Franci C., Wong L.M., Van Damme J., Proost P., Charo I.F. Monocyte chemoattractant protein-3, but not monocyte chemoattractant protein-2, is a functional ligand of the human monocyte chemoattractant protein-1 receptor. J. Immunol. 1995, 154:6511-6517.
    • (1995) J. Immunol. , vol.154 , pp. 6511-6517
    • Franci, C.1    Wong, L.M.2    Van Damme, J.3    Proost, P.4    Charo, I.F.5
  • 98
    • 51349085578 scopus 로고    scopus 로고
    • TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice
    • Frank S., Burbach G.J., Bonin M., Walter M., Streit W., Bechmann I., Deller T. TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice. Glia 2008, 56:1438-1447.
    • (2008) Glia , vol.56 , pp. 1438-1447
    • Frank, S.1    Burbach, G.J.2    Bonin, M.3    Walter, M.4    Streit, W.5    Bechmann, I.6    Deller, T.7
  • 100
    • 55849085357 scopus 로고    scopus 로고
    • MFG-E8 regulates microglial phagocytosis of apoptotic neurons
    • Fuller A.D., Van Eldik L.J. MFG-E8 regulates microglial phagocytosis of apoptotic neurons. J. Neuroimmune Pharmacol. 2008, 3:246-256.
    • (2008) J. Neuroimmune Pharmacol. , vol.3 , pp. 246-256
    • Fuller, A.D.1    Van Eldik, L.J.2
  • 101
    • 0031765770 scopus 로고    scopus 로고
    • Excitotoxic brain injury stimulates expression of the chemokine receptor CCR5 in neonatal rats
    • Galasso J.M., Harrison J.K., Silverstein F.S. Excitotoxic brain injury stimulates expression of the chemokine receptor CCR5 in neonatal rats. Am. J. Pathol. 1998, 153:1631-1640.
    • (1998) Am. J. Pathol. , vol.153 , pp. 1631-1640
    • Galasso, J.M.1    Harrison, J.K.2    Silverstein, F.S.3
  • 103
    • 58149345561 scopus 로고    scopus 로고
    • G-protein-coupled receptor screen reveals a role for chemokine receptor CCR5 in suppressing microglial neurotoxicity
    • Gamo K., Kiryu-Seo S., Konishi H., Aoki S., Matsushima K., Wada K., Kiyama H. G-protein-coupled receptor screen reveals a role for chemokine receptor CCR5 in suppressing microglial neurotoxicity. J. Neurosci. 2008, 28:11980-11988.
    • (2008) J. Neurosci. , vol.28 , pp. 11980-11988
    • Gamo, K.1    Kiryu-Seo, S.2    Konishi, H.3    Aoki, S.4    Matsushima, K.5    Wada, K.6    Kiyama, H.7
  • 105
    • 0030589313 scopus 로고    scopus 로고
    • Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3
    • Garcia-Zepeda E.A., Combadiere C., Rothenberg M.E., Sarafi M.N., Lavigne F., Hamid Q., Murphy P.M., Luster A.D. Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3. J. Immunol. 1996, 157:5613-5626.
    • (1996) J. Immunol. , vol.157 , pp. 5613-5626
    • Garcia-Zepeda, E.A.1    Combadiere, C.2    Rothenberg, M.E.3    Sarafi, M.N.4    Lavigne, F.5    Hamid, Q.6    Murphy, P.M.7    Luster, A.D.8
  • 107
    • 0035851124 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)
    • Garton K.J., Gough P.J., Blobel C.P., Murphy G., Greaves D.R., Dempsey P.J., Raines E.W. Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1). J. Biol. Chem. 2001, 276:37993-38001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 37993-38001
    • Garton, K.J.1    Gough, P.J.2    Blobel, C.P.3    Murphy, G.4    Greaves, D.R.5    Dempsey, P.J.6    Raines, E.W.7
  • 109
    • 0141884377 scopus 로고    scopus 로고
    • P2X7 nucleotide receptor activation enhances IFN gamma-induced type II nitric oxide synthase activity in BV-2 microglial cells
    • Gendron F.P., Chalimoniuk M., Strosznajder J., Shen S., Gonzalez F.A., Weisman G.A., Sun G.Y. P2X7 nucleotide receptor activation enhances IFN gamma-induced type II nitric oxide synthase activity in BV-2 microglial cells. J. Neurochem. 2003, 87:344-352.
    • (2003) J. Neurochem. , vol.87 , pp. 344-352
    • Gendron, F.P.1    Chalimoniuk, M.2    Strosznajder, J.3    Shen, S.4    Gonzalez, F.A.5    Weisman, G.A.6    Sun, G.Y.7
  • 110
    • 73849141097 scopus 로고    scopus 로고
    • The selective adenosine A2A receptor agonist CGS 21680 reduces JNK MAPK activation in oligodendrocytes in injured spinal cord
    • Genovese T., Melani A., Esposito E., Mazzon E., Di Paola R., Bramanti P., Pedata F., Cuzzocrea S. The selective adenosine A2A receptor agonist CGS 21680 reduces JNK MAPK activation in oligodendrocytes in injured spinal cord. Shock 2009, 32:578-585.
    • (2009) Shock , vol.32 , pp. 578-585
    • Genovese, T.1    Melani, A.2    Esposito, E.3    Mazzon, E.4    Di Paola, R.5    Bramanti, P.6    Pedata, F.7    Cuzzocrea, S.8
  • 112
    • 10644237032 scopus 로고    scopus 로고
    • A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis
    • Gibot S., Kolopp-Sarda M.N., Bene M.C., Bollaert P.E., Lozniewski A., Mory F., Levy B., Faure G.C. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J. Exp. Med. 2004, 200:1419-1426.
    • (2004) J. Exp. Med. , vol.200 , pp. 1419-1426
    • Gibot, S.1    Kolopp-Sarda, M.N.2    Bene, M.C.3    Bollaert, P.E.4    Lozniewski, A.5    Mory, F.6    Levy, B.7    Faure, G.C.8
  • 114
    • 65549155435 scopus 로고    scopus 로고
    • ATP induces long-term potentiation of C-fiber-evoked field potentials in spinal dorsal horn: the roles of P2X4 receptors and p38 MAPK in microglia
    • Gong Q.J., Li Y.Y., Xin W.J., Zang Y., Ren W.J., Wei X.H., Zhang T., Liu X.G. ATP induces long-term potentiation of C-fiber-evoked field potentials in spinal dorsal horn: the roles of P2X4 receptors and p38 MAPK in microglia. Glia 2009, 57:583-591.
    • (2009) Glia , vol.57 , pp. 583-591
    • Gong, Q.J.1    Li, Y.Y.2    Xin, W.J.3    Zang, Y.4    Ren, W.J.5    Wei, X.H.6    Zhang, T.7    Liu, X.G.8
  • 118
    • 0042242912 scopus 로고    scopus 로고
    • Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells
    • Gudipaty L., Munetz J., Verhoef P.A., Dubyak G.R. Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells. Am. J. Physiol. Cell Physiol. 2003, 285:C286-C299.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.285
    • Gudipaty, L.1    Munetz, J.2    Verhoef, P.A.3    Dubyak, G.R.4
  • 119
    • 0344687251 scopus 로고    scopus 로고
    • Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-3'-kinase
    • Hammarberg C., Fredholm B.B., Schulte G. Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-3'-kinase. Biochem. Pharmacol. 2004, 67:129-134.
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 129-134
    • Hammarberg, C.1    Fredholm, B.B.2    Schulte, G.3
  • 120
    • 0042731679 scopus 로고    scopus 로고
    • Evidence for functional adenosine A3 receptors in microglia cells
    • Hammarberg C., Schulte G., Fredholm B.B. Evidence for functional adenosine A3 receptors in microglia cells. J. Neurochem. 2003, 86:1051-1054.
    • (2003) J. Neurochem. , vol.86 , pp. 1051-1054
    • Hammarberg, C.1    Schulte, G.2    Fredholm, B.B.3
  • 121
  • 122
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch U.K., Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat. Neurosci. 2007, 10:1387-1394.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 123
    • 80052315340 scopus 로고    scopus 로고
    • Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential
    • Hanke M.L., Kielian T. Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential. Clin. Sci. (Lond.) 2011, 121:367-387.
    • (2011) Clin. Sci. (Lond.) , vol.121 , pp. 367-387
    • Hanke, M.L.1    Kielian, T.2
  • 125
  • 126
  • 127
    • 3242658383 scopus 로고    scopus 로고
    • The CD200 and CD200 receptor cell surface proteins interact through their N-terminal immunoglobulin-like domains
    • Hatherley D., Barclay A.N. The CD200 and CD200 receptor cell surface proteins interact through their N-terminal immunoglobulin-like domains. Eur. J. Immunol. 2004, 34:1688-1694.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 1688-1694
    • Hatherley, D.1    Barclay, A.N.2
  • 130
    • 80053341816 scopus 로고    scopus 로고
    • Spinal P2X(7) receptor mediates microglia activation-induced neuropathic pain in the sciatic nerve injury rat model
    • He W.J., Cui J., Du L., Zhao Y.D., Burnstock G., Zhou H.D., Ruan H.Z. Spinal P2X(7) receptor mediates microglia activation-induced neuropathic pain in the sciatic nerve injury rat model. Behav. Brain Res. 2012, 226:163-170.
    • (2012) Behav. Brain Res. , vol.226 , pp. 163-170
    • He, W.J.1    Cui, J.2    Du, L.3    Zhao, Y.D.4    Burnstock, G.5    Zhou, H.D.6    Ruan, H.Z.7
  • 131
    • 0027935497 scopus 로고
    • Dissociation of adenosine levels from bioenergetic state in experimental brain trauma: potential role in secondary injury
    • Headrick J.P., Bendall M.R., Faden A.I., Vink R. Dissociation of adenosine levels from bioenergetic state in experimental brain trauma: potential role in secondary injury. J. Cereb. Blood Flow Metab. 1994, 14:853-861.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 853-861
    • Headrick, J.P.1    Bendall, M.R.2    Faden, A.I.3    Vink, R.4
  • 132
    • 79956152659 scopus 로고    scopus 로고
    • Selective depletion of Mac-1-expressing microglia in rat subventricular zone does not alter neurogenic response early after stroke
    • Heldmann U., Mine Y., Kokaia Z., Ekdahl C.T., Lindvall O. Selective depletion of Mac-1-expressing microglia in rat subventricular zone does not alter neurogenic response early after stroke. Exp. Neurol. 2011, 229:391-398.
    • (2011) Exp. Neurol. , vol.229 , pp. 391-398
    • Heldmann, U.1    Mine, Y.2    Kokaia, Z.3    Ekdahl, C.T.4    Lindvall, O.5
  • 133
    • 0034046181 scopus 로고    scopus 로고
    • Regulation of antibody responses via antibodies, complement, and Fc receptors
    • Heyman B. Regulation of antibody responses via antibodies, complement, and Fc receptors. Annu. Rev. Immunol. 2000, 18:709-737.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 709-737
    • Heyman, B.1
  • 136
    • 0141893347 scopus 로고    scopus 로고
    • Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells
    • Hirt U.A., Leist M. Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells. Cell Death Differ. 2003, 10:1156-1164.
    • (2003) Cell Death Differ. , vol.10 , pp. 1156-1164
    • Hirt, U.A.1    Leist, M.2
  • 138
    • 0028851635 scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
    • Hori O., Brett J., Slattery T., Cao R., Zhang J., Chen J.X., Nagashima M., Lundh E.R., Vijay S., Nitecki D., et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J. Biol. Chem. 1995, 270:25752-25761.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3    Cao, R.4    Zhang, J.5    Chen, J.X.6    Nagashima, M.7    Lundh, E.R.8    Vijay, S.9    Nitecki, D.10
  • 139
    • 59649089153 scopus 로고    scopus 로고
    • Morphine enhances microglial migration through modulation of P2X4 receptor signaling
    • Horvath R.J., DeLeo J.A. Morphine enhances microglial migration through modulation of P2X4 receptor signaling. J. Neurosci. 2009, 29:998-1005.
    • (2009) J. Neurosci. , vol.29 , pp. 998-1005
    • Horvath, R.J.1    DeLeo, J.A.2
  • 141
    • 84862855771 scopus 로고    scopus 로고
    • Involvement of CX3CR1 in bone cancer pain through the activation of microglia p38 MAPK pathway in the spinal cord
    • Hu J.H., Yang J.P., Liu L., Li C.F., Wang L.N., Ji F.H., Cheng H. Involvement of CX3CR1 in bone cancer pain through the activation of microglia p38 MAPK pathway in the spinal cord. Brain Res. 2012, 1465:1-9.
    • (2012) Brain Res. , vol.1465 , pp. 1-9
    • Hu, J.H.1    Yang, J.P.2    Liu, L.3    Li, C.F.4    Wang, L.N.5    Ji, F.H.6    Cheng, H.7
  • 143
    • 0037666197 scopus 로고    scopus 로고
    • The effect of phosphatases SHP-1 and SHIP-1 on signaling by the ITIM- and ITAM-containing Fcgamma receptors FcgammaRIIB and FcgammaRIIA
    • Huang Z.Y., Hunter S., Kim M.K., Indik Z.K., Schreiber A.D. The effect of phosphatases SHP-1 and SHIP-1 on signaling by the ITIM- and ITAM-containing Fcgamma receptors FcgammaRIIB and FcgammaRIIA. J. Leukoc. Biol. 2003, 73:823-829.
    • (2003) J. Leukoc. Biol. , vol.73 , pp. 823-829
    • Huang, Z.Y.1    Hunter, S.2    Kim, M.K.3    Indik, Z.K.4    Schreiber, A.D.5
  • 148
    • 0036847848 scopus 로고    scopus 로고
    • Scavenger receptors in neurobiology and neuropathology: their role on microglia and other cells of the nervous system
    • Husemann J., Loike J.D., Anankov R., Febbraio M., Silverstein S.C. Scavenger receptors in neurobiology and neuropathology: their role on microglia and other cells of the nervous system. Glia 2002, 40:195-205.
    • (2002) Glia , vol.40 , pp. 195-205
    • Husemann, J.1    Loike, J.D.2    Anankov, R.3    Febbraio, M.4    Silverstein, S.C.5
  • 151
    • 43149123118 scopus 로고    scopus 로고
    • Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia
    • Irino Y., Nakamura Y., Inoue K., Kohsaka S., Ohsawa K. Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia. J. Neurosci. Res. 2008, 86:1511-1519.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 1511-1519
    • Irino, Y.1    Nakamura, Y.2    Inoue, K.3    Kohsaka, S.4    Ohsawa, K.5
  • 152
    • 62849123774 scopus 로고    scopus 로고
    • Cross-regulation of signaling by ITAM-associated receptors
    • Ivashkiv L.B. Cross-regulation of signaling by ITAM-associated receptors. Nat. Immunol. 2009, 10:340-347.
    • (2009) Nat. Immunol. , vol.10 , pp. 340-347
    • Ivashkiv, L.B.1
  • 153
    • 63449112694 scopus 로고    scopus 로고
    • Critical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis
    • Jakus Z., Simon E., Frommhold D., Sperandio M., Mocsai A. Critical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis. J. Exp. Med. 2009, 206:577-593.
    • (2009) J. Exp. Med. , vol.206 , pp. 577-593
    • Jakus, Z.1    Simon, E.2    Frommhold, D.3    Sperandio, M.4    Mocsai, A.5
  • 154
    • 0037025261 scopus 로고    scopus 로고
    • P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system
    • James G., Butt A.M. P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system. Eur. J. Pharmacol. 2002, 447:247-260.
    • (2002) Eur. J. Pharmacol. , vol.447 , pp. 247-260
    • James, G.1    Butt, A.M.2
  • 156
    • 71949094540 scopus 로고    scopus 로고
    • Sulfatide, a major lipid component of myelin sheath, activates inflammatory responses as an endogenous stimulator in brain-resident immune cells
    • Jeon S.B., Yoon H.J., Park S.H., Kim I.H., Park E.J. Sulfatide, a major lipid component of myelin sheath, activates inflammatory responses as an endogenous stimulator in brain-resident immune cells. J. Immunol. 2008, 181:8077-8087.
    • (2008) J. Immunol. , vol.181 , pp. 8077-8087
    • Jeon, S.B.1    Yoon, H.J.2    Park, S.H.3    Kim, I.H.4    Park, E.J.5
  • 157
    • 0033608548 scopus 로고    scopus 로고
    • Involvement of P2 purinoceptors and the nitric oxide pathway in [3H]purine outflow evoked by short-term hypoxia and hypoglycemia in rat hippocampal slices
    • Juranyi Z., Sperlagh B., Vizi E.S. Involvement of P2 purinoceptors and the nitric oxide pathway in [3H]purine outflow evoked by short-term hypoxia and hypoglycemia in rat hippocampal slices. Brain Res. 1999, 823:183-190.
    • (1999) Brain Res. , vol.823 , pp. 183-190
    • Juranyi, Z.1    Sperlagh, B.2    Vizi, E.S.3
  • 158
    • 1942422683 scopus 로고    scopus 로고
    • Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release
    • Kahlenberg J.M., Dubyak G.R. Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. Am. J. Physiol. Cell Physiol. 2004, 286:C1100-C1108.
    • (2004) Am. J. Physiol. Cell Physiol. , vol.286
    • Kahlenberg, J.M.1    Dubyak, G.R.2
  • 159
    • 57249111810 scopus 로고    scopus 로고
    • Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT
    • Kataoka A., Tozaki-Saitoh H., Koga Y., Tsuda M., Inoue K. Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT. J. Neurochem. 2009, 108:115-125.
    • (2009) J. Neurochem. , vol.108 , pp. 115-125
    • Kataoka, A.1    Tozaki-Saitoh, H.2    Koga, Y.3    Tsuda, M.4    Inoue, K.5
  • 162
    • 15944383043 scopus 로고    scopus 로고
    • Dap12 and Trem2, molecules involved in innate immunity and neurodegeneration, are co-expressed in the CNS
    • Kiialainen A., Hovanes K., Paloneva J., Kopra O., Peltonen L. Dap12 and Trem2, molecules involved in innate immunity and neurodegeneration, are co-expressed in the CNS. Neurobiol. Dis. 2005, 18:314-322.
    • (2005) Neurobiol. Dis. , vol.18 , pp. 314-322
    • Kiialainen, A.1    Hovanes, K.2    Paloneva, J.3    Kopra, O.4    Peltonen, L.5
  • 163
    • 45049087782 scopus 로고    scopus 로고
    • TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration
    • Kilic U., Kilic E., Matter C.M., Bassetti C.L., Hermann D.M. TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration. Neurobiol. Dis. 2008, 31:33-40.
    • (2008) Neurobiol. Dis. , vol.31 , pp. 33-40
    • Kilic, U.1    Kilic, E.2    Matter, C.M.3    Bassetti, C.L.4    Hermann, D.M.5
  • 164
    • 79953164964 scopus 로고    scopus 로고
    • Uridine 5'-diphosphate induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor
    • Kim B., Jeong H.K., Kim J.H., Lee S.Y., Jou I., Joe E.H. Uridine 5'-diphosphate induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor. J. Immunol. 2011, 186:3701-3709.
    • (2011) J. Immunol. , vol.186 , pp. 3701-3709
    • Kim, B.1    Jeong, H.K.2    Kim, J.H.3    Lee, S.Y.4    Jou, I.5    Joe, E.H.6
  • 166
  • 168
    • 41849097003 scopus 로고    scopus 로고
    • CD7 expression and galectin-1-induced apoptosis of immature thymocytes are directly regulated by NF-kappaB upon T-cell activation
    • Koh H.S., Lee C., Lee K.S., Ham C.S., Seong R.H., Kim S.S., Jeon S.H. CD7 expression and galectin-1-induced apoptosis of immature thymocytes are directly regulated by NF-kappaB upon T-cell activation. Biochem. Biophys. Res. Commun. 2008, 370:149-153.
    • (2008) Biochem. Biophys. Res. Commun. , vol.370 , pp. 149-153
    • Koh, H.S.1    Lee, C.2    Lee, K.S.3    Ham, C.S.4    Seong, R.H.5    Kim, S.S.6    Jeon, S.H.7
  • 170
  • 171
    • 0031578865 scopus 로고    scopus 로고
    • Source of extracellular brain adenosine during hypoxia in fetal sheep
    • Koos B.J., Kruger L., Murray T.F. Source of extracellular brain adenosine during hypoxia in fetal sheep. Brain Res. 1997, 778:439-442.
    • (1997) Brain Res. , vol.778 , pp. 439-442
    • Koos, B.J.1    Kruger, L.2    Murray, T.F.3
  • 172
    • 0032881850 scopus 로고    scopus 로고
    • Charting the fate of the good cholesterol: identification and characterization of the high-density lipoprotein receptor SR-BI
    • Krieger M. Charting the fate of the good cholesterol: identification and characterization of the high-density lipoprotein receptor SR-BI. Annu. Rev. Biochem. 1999, 68:523-558.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 523-558
    • Krieger, M.1
  • 173
    • 84884182262 scopus 로고    scopus 로고
    • Contribution of macrophages to enhanced regenerative capacity of dorsal root ganglia sensory neurons by conditioning injury
    • Kwon M.J., Kim J., Shin H., Jeong S.R., Kang Y.M., Choi J.Y., Hwang D.H., Kim B.G. Contribution of macrophages to enhanced regenerative capacity of dorsal root ganglia sensory neurons by conditioning injury. J. Neurosci. 2013, 33:15095-15108.
    • (2013) J. Neurosci. , vol.33 , pp. 15095-15108
    • Kwon, M.J.1    Kim, J.2    Shin, H.3    Jeong, S.R.4    Kang, Y.M.5    Choi, J.Y.6    Hwang, D.H.7    Kim, B.G.8
  • 174
    • 33847785649 scopus 로고    scopus 로고
    • Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain
    • Lalancette-Hebert M., Gowing G., Simard A., Weng Y.C., Kriz J. Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain. J. Neurosci. 2007, 27:2596-2605.
    • (2007) J. Neurosci. , vol.27 , pp. 2596-2605
    • Lalancette-Hebert, M.1    Gowing, G.2    Simard, A.3    Weng, Y.C.4    Kriz, J.5
  • 176
    • 0029656266 scopus 로고    scopus 로고
    • The source of brain adenosine outflow during ischemia and electrical stimulation
    • Latini S., Corsi C., Pedata F., Pepeu G. The source of brain adenosine outflow during ischemia and electrical stimulation. Neurochem. Int. 1996, 28:113-118.
    • (1996) Neurochem. Int. , vol.28 , pp. 113-118
    • Latini, S.1    Corsi, C.2    Pedata, F.3    Pepeu, G.4
  • 177
    • 0034765853 scopus 로고    scopus 로고
    • Adenosine in the central nervous system: release mechanisms and extracellular concentrations
    • Latini S., Pedata F. Adenosine in the central nervous system: release mechanisms and extracellular concentrations. J. Neurochem. 2001, 79:463-484.
    • (2001) J. Neurochem. , vol.79 , pp. 463-484
    • Latini, S.1    Pedata, F.2
  • 178
    • 0035503074 scopus 로고    scopus 로고
    • Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease
    • Le W., Rowe D., Xie W., Ortiz I., He Y., Appel S.H. Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease. J. Neurosci. 2001, 21:8447-8455.
    • (2001) J. Neurosci. , vol.21 , pp. 8447-8455
    • Le, W.1    Rowe, D.2    Xie, W.3    Ortiz, I.4    He, Y.5    Appel, S.H.6
  • 179
    • 77956103055 scopus 로고    scopus 로고
    • Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice
    • Lech M., Avila-Ferrufino A., Skuginna V., Susanti H.E., Anders H.J. Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice. Int. Immunol. 2010, 22:717-728.
    • (2010) Int. Immunol. , vol.22 , pp. 717-728
    • Lech, M.1    Avila-Ferrufino, A.2    Skuginna, V.3    Susanti, H.E.4    Anders, H.J.5
  • 180
    • 32544439901 scopus 로고    scopus 로고
    • Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells
    • Lee J.Y., Jhun B.S., Oh Y.T., Lee J.H., Choe W., Baik H.H., Ha J., Yoon K.S., Kim S.S., Kang I. Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells. Neurosci. Lett. 2006, 396:1-6.
    • (2006) Neurosci. Lett. , vol.396 , pp. 1-6
    • Lee, J.Y.1    Jhun, B.S.2    Oh, Y.T.3    Lee, J.H.4    Choe, W.5    Baik, H.H.6    Ha, J.7    Yoon, K.S.8    Kim, S.S.9    Kang, I.10
  • 181
    • 77957316313 scopus 로고    scopus 로고
    • CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models
    • Lee S., Varvel N.H., Konerth M.E., Xu G., Cardona A.E., Ransohoff R.M., Lamb B.T. CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models. Am. J. Pathol. 2010, 177:2549-2562.
    • (2010) Am. J. Pathol. , vol.177 , pp. 2549-2562
    • Lee, S.1    Varvel, N.H.2    Konerth, M.E.3    Xu, G.4    Cardona, A.E.5    Ransohoff, R.M.6    Lamb, B.T.7
  • 182
    • 0142155221 scopus 로고    scopus 로고
    • Toll-like receptors and inflammation in the CNS
    • Lee S.J., Lee S. Toll-like receptors and inflammation in the CNS. Curr. Drug Targets Inflamm. Allergy 2002, 1:181-191.
    • (2002) Curr. Drug Targets Inflamm. Allergy , vol.1 , pp. 181-191
    • Lee, S.J.1    Lee, S.2
  • 184
    • 0034655219 scopus 로고    scopus 로고
    • Mechanism for the isotype dependence of antibody-mediated toxicity in Cryptococcus neoformans-infected mice
    • Lendvai N., Qu X.W., Hsueh W., Casadevall A. Mechanism for the isotype dependence of antibody-mediated toxicity in Cryptococcus neoformans-infected mice. J. Immunol. 2000, 164:4367-4374.
    • (2000) J. Immunol. , vol.164 , pp. 4367-4374
    • Lendvai, N.1    Qu, X.W.2    Hsueh, W.3    Casadevall, A.4
  • 187
    • 80155123520 scopus 로고    scopus 로고
    • Hypoxia induced amoeboid microglial cell activation in postnatal rat brain is mediated by ATP receptor P2X4
    • Li F., Wang L., Li J.W., Gong M., He L., Feng R., Dai Z., Li S.Q. Hypoxia induced amoeboid microglial cell activation in postnatal rat brain is mediated by ATP receptor P2X4. BMC Neurosci. 2011, 12:111.
    • (2011) BMC Neurosci. , vol.12 , pp. 111
    • Li, F.1    Wang, L.2    Li, J.W.3    Gong, M.4    He, L.5    Feng, R.6    Dai, Z.7    Li, S.Q.8
  • 190
    • 84869170399 scopus 로고    scopus 로고
    • Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx
    • Linnartz B., Neumann H. Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx. Glia 2013, 61:37-46.
    • (2013) Glia , vol.61 , pp. 37-46
    • Linnartz, B.1    Neumann, H.2
  • 191
    • 0036045364 scopus 로고    scopus 로고
    • Galectins: novel anti-inflammatory drug targets
    • Liu F.T. Galectins: novel anti-inflammatory drug targets. Expert Opin. Ther. Targets 2002, 6:461-468.
    • (2002) Expert Opin. Ther. Targets , vol.6 , pp. 461-468
    • Liu, F.T.1
  • 192
    • 78650338241 scopus 로고    scopus 로고
    • CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-beta phagocytosis
    • Liu Z., Condello C., Schain A., Harb R., Grutzendler J. CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-beta phagocytosis. J. Neurosci. 2010, 30:17091-17101.
    • (2010) J. Neurosci. , vol.30 , pp. 17091-17101
    • Liu, Z.1    Condello, C.2    Schain, A.3    Harb, R.4    Grutzendler, J.5
  • 193
    • 33845938979 scopus 로고    scopus 로고
    • Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia
    • Liu Z., Fan Y., Won S.J., Neumann M., Hu D., Zhou L., Weinstein P.R., Liu J. Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia. Stroke 2007, 38:146-152.
    • (2007) Stroke , vol.38 , pp. 146-152
    • Liu, Z.1    Fan, Y.2    Won, S.J.3    Neumann, M.4    Hu, D.5    Zhou, L.6    Weinstein, P.R.7    Liu, J.8
  • 195
    • 0037110640 scopus 로고    scopus 로고
    • Modeling Alzheimer's disease immune therapy mechanisms: interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide
    • Lue L.F., Walker D.G. Modeling Alzheimer's disease immune therapy mechanisms: interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide. J. Neurosci. Res. 2002, 70:599-610.
    • (2002) J. Neurosci. Res. , vol.70 , pp. 599-610
    • Lue, L.F.1    Walker, D.G.2
  • 196
    • 0034840664 scopus 로고    scopus 로고
    • Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism
    • Lue L.F., Walker D.G., Brachova L., Beach T.G., Rogers J., Schmidt A.M., Stern D.M., Yan S.D. Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism. Exp. Neurol. 2001, 171:29-45.
    • (2001) Exp. Neurol. , vol.171 , pp. 29-45
    • Lue, L.F.1    Walker, D.G.2    Brachova, L.3    Beach, T.G.4    Rogers, J.5    Schmidt, A.M.6    Stern, D.M.7    Yan, S.D.8
  • 197
    • 34547680192 scopus 로고    scopus 로고
    • CD200 ligand receptor interaction modulates microglial activation in vivo and in vitro: a role for IL-4
    • Lyons A., Downer E.J., Crotty S., Nolan Y.M., Mills K.H., Lynch M.A. CD200 ligand receptor interaction modulates microglial activation in vivo and in vitro: a role for IL-4. J. Neurosci. 2007, 27:8309-8313.
    • (2007) J. Neurosci. , vol.27 , pp. 8309-8313
    • Lyons, A.1    Downer, E.J.2    Crotty, S.3    Nolan, Y.M.4    Mills, K.H.5    Lynch, M.A.6
  • 198
    • 68949200462 scopus 로고    scopus 로고
    • Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attenuates microglial activation in vivo and in vitro
    • Lyons A., Lynch A.M., Downer E.J., Hanley R., O'Sullivan J.B., Smith A., Lynch M.A. Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attenuates microglial activation in vivo and in vitro. J. Neurochem. 2009, 110:1547-1556.
    • (2009) J. Neurochem. , vol.110 , pp. 1547-1556
    • Lyons, A.1    Lynch, A.M.2    Downer, E.J.3    Hanley, R.4    O'Sullivan, J.B.5    Smith, A.6    Lynch, M.A.7
  • 200
    • 0842284040 scopus 로고    scopus 로고
    • Neurons and astrocytes respond to prion infection by inducing microglia recruitment
    • Marella M., Chabry J. Neurons and astrocytes respond to prion infection by inducing microglia recruitment. J. Neurosci. 2004, 24:620-627.
    • (2004) J. Neurosci. , vol.24 , pp. 620-627
    • Marella, M.1    Chabry, J.2
  • 201
    • 34247166592 scopus 로고    scopus 로고
    • Expression of CD200 by macrophage-like cells in ischemic core of rat brain after transient middle cerebral artery occlusion
    • Matsumoto H., Kumon Y., Watanabe H., Ohnishi T., Takahashi H., Imai Y., Tanaka J. Expression of CD200 by macrophage-like cells in ischemic core of rat brain after transient middle cerebral artery occlusion. Neurosci. Lett. 2007, 418:44-48.
    • (2007) Neurosci. Lett. , vol.418 , pp. 44-48
    • Matsumoto, H.1    Kumon, Y.2    Watanabe, H.3    Ohnishi, T.4    Takahashi, H.5    Imai, Y.6    Tanaka, J.7
  • 204
    • 77954127754 scopus 로고    scopus 로고
    • Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells
    • Mihrshahi R., Barclay A.N., Brown M.H. Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells. J. Immunol. 2009, 183:4879-4886.
    • (2009) J. Immunol. , vol.183 , pp. 4879-4886
    • Mihrshahi, R.1    Barclay, A.N.2    Brown, M.H.3
  • 205
    • 78650640168 scopus 로고    scopus 로고
    • Downstream of tyrosine kinase 1 and 2 play opposing roles in CD200 receptor signaling
    • Mihrshahi R., Brown M.H. Downstream of tyrosine kinase 1 and 2 play opposing roles in CD200 receptor signaling. J. Immunol. 2010, 185:7216-7222.
    • (2010) J. Immunol. , vol.185 , pp. 7216-7222
    • Mihrshahi, R.1    Brown, M.H.2
  • 212
    • 64849087753 scopus 로고    scopus 로고
    • The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore
    • Monif M., Reid C.A., Powell K.L., Smart M.L., Williams D.A. The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore. J. Neurosci. 2009, 29:3781-3791.
    • (2009) J. Neurosci. , vol.29 , pp. 3781-3791
    • Monif, M.1    Reid, C.A.2    Powell, K.L.3    Smart, M.L.4    Williams, D.A.5
  • 214
    • 0037198975 scopus 로고    scopus 로고
    • Ablation of the chemokine monocyte chemoattractant protein-1 delays retrograde neuronal degeneration, attenuates microglial activation, and alters expression of cell death molecules
    • Muessel M.J., Klein R.M., Wilson A.M., Berman N.E. Ablation of the chemokine monocyte chemoattractant protein-1 delays retrograde neuronal degeneration, attenuates microglial activation, and alters expression of cell death molecules. Brain Res. Mol. Brain Res. 2002, 103:12-27.
    • (2002) Brain Res. Mol. Brain Res. , vol.103 , pp. 12-27
    • Muessel, M.J.1    Klein, R.M.2    Wilson, A.M.3    Berman, N.E.4
  • 216
    • 0028970253 scopus 로고
    • Signal transduction and ligand specificity of the human monocyte chemoattractant protein-1 receptor in transfected embryonic kidney cells
    • Myers S.J., Wong L.M., Charo I.F. Signal transduction and ligand specificity of the human monocyte chemoattractant protein-1 receptor in transfected embryonic kidney cells. J. Biol. Chem. 1995, 270:5786-5792.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5786-5792
    • Myers, S.J.1    Wong, L.M.2    Charo, I.F.3
  • 218
    • 84860876124 scopus 로고    scopus 로고
    • Hematopoietic CC-chemokine receptor 2 (CCR2) competent cells are protective for the cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease
    • Naert G., Rivest S. Hematopoietic CC-chemokine receptor 2 (CCR2) competent cells are protective for the cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease. Mol. Med. 2012, 18:297-313.
    • (2012) Mol. Med. , vol.18 , pp. 297-313
    • Naert, G.1    Rivest, S.2
  • 219
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • Nimmerjahn F., Ravetch J.V. Fcgamma receptors as regulators of immune responses. Nat. Rev. Immunol. 2008, 8:34-47.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 220
    • 0032510831 scopus 로고    scopus 로고
    • Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia?
    • Nishiyori A., Minami M., Ohtani Y., Takami S., Yamamoto J., Kawaguchi N., Kume T., Akaike A., Satoh M. Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia?. FEBS Lett. 1998, 429:167-172.
    • (1998) FEBS Lett. , vol.429 , pp. 167-172
    • Nishiyori, A.1    Minami, M.2    Ohtani, Y.3    Takami, S.4    Yamamoto, J.5    Kawaguchi, N.6    Kume, T.7    Akaike, A.8    Satoh, M.9
  • 221
    • 78751561861 scopus 로고    scopus 로고
    • Fractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression
    • Noda M., Doi Y., Liang J., Kawanokuchi J., Sonobe Y., Takeuchi H., Mizuno T., Suzumura A. Fractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression. J. Biol. Chem. 2011, 286:2308-2319.
    • (2011) J. Biol. Chem. , vol.286 , pp. 2308-2319
    • Noda, M.1    Doi, Y.2    Liang, J.3    Kawanokuchi, J.4    Sonobe, Y.5    Takeuchi, H.6    Mizuno, T.7    Suzumura, A.8
  • 222
    • 0035317489 scopus 로고    scopus 로고
    • Organization of the chemokine genes in the human and mouse major clusters of CC and CXC chemokines: diversification between the two species
    • Nomiyama H., Mera A., Ohneda O., Miura R., Suda T., Yoshie O. Organization of the chemokine genes in the human and mouse major clusters of CC and CXC chemokines: diversification between the two species. Genes Immunol. 2001, 2:110-113.
    • (2001) Genes Immunol. , vol.2 , pp. 110-113
    • Nomiyama, H.1    Mera, A.2    Ohneda, O.3    Miura, R.4    Suda, T.5    Yoshie, O.6
  • 223
    • 33947540584 scopus 로고    scopus 로고
    • Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis
    • Ohsawa K., Irino Y., Nakamura Y., Akazawa C., Inoue K., Kohsaka S. Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis. Glia 2007, 55:604-616.
    • (2007) Glia , vol.55 , pp. 604-616
    • Ohsawa, K.1    Irino, Y.2    Nakamura, Y.3    Akazawa, C.4    Inoue, K.5    Kohsaka, S.6
  • 224
    • 77952573195 scopus 로고    scopus 로고
    • P2Y12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP
    • Ohsawa K., Irino Y., Sanagi T., Nakamura Y., Suzuki E., Inoue K., Kohsaka S. P2Y12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP. Glia 2010, 58:790-801.
    • (2010) Glia , vol.58 , pp. 790-801
    • Ohsawa, K.1    Irino, Y.2    Sanagi, T.3    Nakamura, Y.4    Suzuki, E.5    Inoue, K.6    Kohsaka, S.7
  • 225
    • 84859635614 scopus 로고    scopus 로고
    • Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration
    • Ohsawa K., Sanagi T., Nakamura Y., Suzuki E., Inoue K., Kohsaka S. Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration. J. Neurochem. 2012, 121:217-227.
    • (2012) J. Neurochem. , vol.121 , pp. 217-227
    • Ohsawa, K.1    Sanagi, T.2    Nakamura, Y.3    Suzuki, E.4    Inoue, K.5    Kohsaka, S.6
  • 226
    • 0032547038 scopus 로고    scopus 로고
    • Expression of stromal cell-derived factor-1 and CXCR4 chemokine receptor mRNAs in cultured rat glial and neuronal cells
    • Ohtani Y., Minami M., Kawaguchi N., Nishiyori A., Yamamoto J., Takami S., Satoh M. Expression of stromal cell-derived factor-1 and CXCR4 chemokine receptor mRNAs in cultured rat glial and neuronal cells. Neurosci. Lett. 1998, 249:163-166.
    • (1998) Neurosci. Lett. , vol.249 , pp. 163-166
    • Ohtani, Y.1    Minami, M.2    Kawaguchi, N.3    Nishiyori, A.4    Yamamoto, J.5    Takami, S.6    Satoh, M.7
  • 227
    • 0035794312 scopus 로고    scopus 로고
    • CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis
    • Oldenborg P.A., Gresham H.D., Lindberg F.P. CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis. J. Exp. Med. 2001, 193:855-862.
    • (2001) J. Exp. Med. , vol.193 , pp. 855-862
    • Oldenborg, P.A.1    Gresham, H.D.2    Lindberg, F.P.3
  • 228
    • 4644232615 scopus 로고    scopus 로고
    • Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
    • Olson J.K., Miller S.D. Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J. Immunol. 2004, 173:3916-3924.
    • (2004) J. Immunol. , vol.173 , pp. 3916-3924
    • Olson, J.K.1    Miller, S.D.2
  • 229
    • 77956104594 scopus 로고    scopus 로고
    • Microglial receptor for advanced glycation end product-dependent signal pathway drives beta-amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex
    • Origlia N., Bonadonna C., Rosellini A., Leznik E., Arancio O., Yan S.S., Domenici L. Microglial receptor for advanced glycation end product-dependent signal pathway drives beta-amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex. J. Neurosci. 2010, 30:11414-11425.
    • (2010) J. Neurosci. , vol.30 , pp. 11414-11425
    • Origlia, N.1    Bonadonna, C.2    Rosellini, A.3    Leznik, E.4    Arancio, O.5    Yan, S.S.6    Domenici, L.7
  • 230
  • 231
    • 0346995361 scopus 로고    scopus 로고
    • Cross-talk between Fc receptors and integrins
    • Ortiz-Stern A., Rosales C. Cross-talk between Fc receptors and integrins. Immunol. Lett. 2003, 90:137-143.
    • (2003) Immunol. Lett. , vol.90 , pp. 137-143
    • Ortiz-Stern, A.1    Rosales, C.2
  • 235
    • 0029114537 scopus 로고
    • Determinants of the phagocytic signal mediated by the type IIIA Fc gamma receptor, Fc gamma RIIIA: sequence requirements and interaction with protein-tyrosine kinases
    • Park J.G., Schreiber A.D. Determinants of the phagocytic signal mediated by the type IIIA Fc gamma receptor, Fc gamma RIIIA: sequence requirements and interaction with protein-tyrosine kinases. Proc. Natl. Acad. Sci. U. S. A. 1995, 92:7381-7385.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 7381-7385
    • Park, J.G.1    Schreiber, A.D.2
  • 237
    • 0038143359 scopus 로고    scopus 로고
    • P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease
    • Parvathenani L.K., Tertyshnikova S., Greco C.R., Roberts S.B., Robertson B., Posmantur R. P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease. J. Biol. Chem. 2003, 278:13309-13317.
    • (2003) J. Biol. Chem. , vol.278 , pp. 13309-13317
    • Parvathenani, L.K.1    Tertyshnikova, S.2    Greco, C.R.3    Roberts, S.B.4    Robertson, B.5    Posmantur, R.6
  • 238
  • 240
    • 65449146377 scopus 로고    scopus 로고
    • Emerging strategies for exploiting cannabinoid receptor agonists as medicines
    • Pertwee R.G. Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br. J. Pharmacol. 2009, 156:397-411.
    • (2009) Br. J. Pharmacol. , vol.156 , pp. 397-411
    • Pertwee, R.G.1
  • 242
    • 84856697436 scopus 로고    scopus 로고
    • Tissue plasminogen activator induces microglial inflammation via a noncatalytic molecular mechanism involving activation of mitogen-activated protein kinases and Akt signaling pathways and AnnexinA2 and Galectin-1 receptors
    • Pineda D., Ampurdanes C., Medina M.G., Serratosa J., Tusell J.M., Saura J., Planas A.M., Navarro P. Tissue plasminogen activator induces microglial inflammation via a noncatalytic molecular mechanism involving activation of mitogen-activated protein kinases and Akt signaling pathways and AnnexinA2 and Galectin-1 receptors. Glia 2012, 60:526-540.
    • (2012) Glia , vol.60 , pp. 526-540
    • Pineda, D.1    Ampurdanes, C.2    Medina, M.G.3    Serratosa, J.4    Tusell, J.M.5    Saura, J.6    Planas, A.M.7    Navarro, P.8
  • 243
    • 33745266414 scopus 로고    scopus 로고
    • Triggering receptor expressed in myeloid cells 2 (TREM2) trafficking in microglial cells: continuous shuttling to and from the plasma membrane regulated by cell stimulation
    • Prada I., Ongania G.N., Buonsanti C., Panina-Bordignon P., Meldolesi J. Triggering receptor expressed in myeloid cells 2 (TREM2) trafficking in microglial cells: continuous shuttling to and from the plasma membrane regulated by cell stimulation. Neuroscience 2006, 140:1139-1148.
    • (2006) Neuroscience , vol.140 , pp. 1139-1148
    • Prada, I.1    Ongania, G.N.2    Buonsanti, C.3    Panina-Bordignon, P.4    Meldolesi, J.5
  • 245
    • 0030744254 scopus 로고    scopus 로고
    • The leukocyte/neuron cell surface antigen OX2 binds to a ligand on macrophages
    • Preston S., Wright G.J., Starr K., Barclay A.N., Brown M.H. The leukocyte/neuron cell surface antigen OX2 binds to a ligand on macrophages. Eur. J. Immunol. 1997, 27:1911-1918.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1911-1918
    • Preston, S.1    Wright, G.J.2    Starr, K.3    Barclay, A.N.4    Brown, M.H.5
  • 246
    • 0010875433 scopus 로고    scopus 로고
    • Identification on human CD36 of a domain (155-183) implicated in binding oxidized low-density lipoproteins (Ox-LDL)
    • Puente Navazo M.D., Daviet L., Ninio E., McGregor J.L. Identification on human CD36 of a domain (155-183) implicated in binding oxidized low-density lipoproteins (Ox-LDL). Arterioscler. Thromb. Vasc. Biol. 1996, 16:1033-1039.
    • (1996) Arterioscler. Thromb. Vasc. Biol. , vol.16 , pp. 1033-1039
    • Puente Navazo, M.D.1    Daviet, L.2    Ninio, E.3    McGregor, J.L.4
  • 247
    • 78449279872 scopus 로고    scopus 로고
    • Galectin-1 enhances astrocytic BDNF production and improves functional outcome in rats following ischemia
    • Qu W.S., Wang Y.H., Wang J.P., Tang Y.X., Zhang Q., Tian D.S., Yu Z.Y., Xie M.J., Wang W. Galectin-1 enhances astrocytic BDNF production and improves functional outcome in rats following ischemia. Neurochem. Res. 2010, 35:1716-1724.
    • (2010) Neurochem. Res. , vol.35 , pp. 1716-1724
    • Qu, W.S.1    Wang, Y.H.2    Wang, J.P.3    Tang, Y.X.4    Zhang, Q.5    Tian, D.S.6    Yu, Z.Y.7    Xie, M.J.8    Wang, W.9
  • 248
    • 67349258025 scopus 로고    scopus 로고
    • Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation
    • Rabinovich G.A., Toscano M.A. Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation. Nat. Rev. Immunol. 2009, 9:338-352.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 338-352
    • Rabinovich, G.A.1    Toscano, M.A.2
  • 249
    • 34548022378 scopus 로고    scopus 로고
    • Differential regulation of microglial P2X4 and P2X7 ATP receptors following LPS-induced activation
    • Raouf R., Chabot-Dore A.J., Ase A.R., Blais D., Seguela P. Differential regulation of microglial P2X4 and P2X7 ATP receptors following LPS-induced activation. Neuropharmacology 2007, 53:496-504.
    • (2007) Neuropharmacology , vol.53 , pp. 496-504
    • Raouf, R.1    Chabot-Dore, A.J.2    Ase, A.R.3    Blais, D.4    Seguela, P.5
  • 252
    • 80755180853 scopus 로고    scopus 로고
    • Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways
    • Ravichandran K.S. Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways. Immunity 2011, 35:445-455.
    • (2011) Immunity , vol.35 , pp. 445-455
    • Ravichandran, K.S.1
  • 253
    • 70349323417 scopus 로고    scopus 로고
    • CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation
    • Reed-Geaghan E.G., Savage J.C., Hise A.G., Landreth G.E. CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation. J. Neurosci. 2009, 29:11982-11992.
    • (2009) J. Neurosci. , vol.29 , pp. 11982-11992
    • Reed-Geaghan, E.G.1    Savage, J.C.2    Hise, A.G.3    Landreth, G.E.4
  • 254
    • 0028947880 scopus 로고
    • Proinflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis
    • Ren Y., Savill J. Proinflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis. J. Immunol. 1995, 154:2366-2374.
    • (1995) J. Immunol. , vol.154 , pp. 2366-2374
    • Ren, Y.1    Savill, J.2
  • 257
    • 0141450468 scopus 로고    scopus 로고
    • Microglia and macrophage activation and the regulation of complement-receptor-3 (CR3/MAC-1)-mediated myelin phagocytosis in injury and disease
    • Rotshenker S. Microglia and macrophage activation and the regulation of complement-receptor-3 (CR3/MAC-1)-mediated myelin phagocytosis in injury and disease. J. Mol. Neurosci. 2003, 21:65-72.
    • (2003) J. Mol. Neurosci. , vol.21 , pp. 65-72
    • Rotshenker, S.1
  • 258
    • 0030698047 scopus 로고    scopus 로고
    • Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection
    • Rottman J.B., Ganley K.P., Williams K., Wu L., Mackay C.R., Ringler D.J. Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection. Am. J. Pathol. 1997, 151:1341-1351.
    • (1997) Am. J. Pathol. , vol.151 , pp. 1341-1351
    • Rottman, J.B.1    Ganley, K.P.2    Williams, K.3    Wu, L.4    Mackay, C.R.5    Ringler, D.J.6
  • 259
    • 77952014394 scopus 로고    scopus 로고
    • CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin
    • Saini V., Marchese A., Majetschak M. CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin. J. Biol. Chem. 2010, 285:15566-15576.
    • (2010) J. Biol. Chem. , vol.285 , pp. 15566-15576
    • Saini, V.1    Marchese, A.2    Majetschak, M.3
  • 262
    • 0034192082 scopus 로고    scopus 로고
    • Kinetics and mechanism of ATP-dependent IL-1 beta release from microglial cells
    • Sanz J.M., Di Virgilio F. Kinetics and mechanism of ATP-dependent IL-1 beta release from microglial cells. J. Immunol. 2000, 164:4893-4898.
    • (2000) J. Immunol. , vol.164 , pp. 4893-4898
    • Sanz, J.M.1    Di Virgilio, F.2
  • 263
    • 0344013132 scopus 로고    scopus 로고
    • Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain
    • Sasaki Y., Hoshi M., Akazawa C., Nakamura Y., Tsuzuki H., Inoue K., Kohsaka S. Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain. Glia 2003, 44:242-250.
    • (2003) Glia , vol.44 , pp. 242-250
    • Sasaki, Y.1    Hoshi, M.2    Akazawa, C.3    Nakamura, Y.4    Tsuzuki, H.5    Inoue, K.6    Kohsaka, S.7
  • 264
    • 79952535866 scopus 로고    scopus 로고
    • Galectin-3 expression in delayed neuronal death of hippocampal CA1 following transient forebrain ischemia, and its inhibition by hypothermia
    • Satoh K., Niwa M., Goda W., Binh N.H., Nakashima M., Takamatsu M., Hara A. Galectin-3 expression in delayed neuronal death of hippocampal CA1 following transient forebrain ischemia, and its inhibition by hypothermia. Brain Res. 2011, 1382:266-274.
    • (2011) Brain Res. , vol.1382 , pp. 266-274
    • Satoh, K.1    Niwa, M.2    Goda, W.3    Binh, N.H.4    Nakashima, M.5    Takamatsu, M.6    Hara, A.7
  • 266
    • 34848825439 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors in neurological disease: raise, retain, or reduce?
    • Savarin-Vuaillat C., Ransohoff R.M. Chemokines and chemokine receptors in neurological disease: raise, retain, or reduce?. Neurotherapeutics 2007, 4:590-601.
    • (2007) Neurotherapeutics , vol.4 , pp. 590-601
    • Savarin-Vuaillat, C.1    Ransohoff, R.M.2
  • 267
    • 0026453281 scopus 로고
    • Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis
    • Savill J., Hogg N., Ren Y., Haslett C. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J. Clin. Invest. 1992, 90:1513-1522.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1513-1522
    • Savill, J.1    Hogg, N.2    Ren, Y.3    Haslett, C.4
  • 268
    • 68649107955 scopus 로고    scopus 로고
    • The role of CC chemokine receptor 2 on microglia activation and blood-borne cell recruitment after transient focal cerebral ischemia in mice
    • Schilling M., Strecker J.K., Ringelstein E.B., Schabitz W.R., Kiefer R. The role of CC chemokine receptor 2 on microglia activation and blood-borne cell recruitment after transient focal cerebral ischemia in mice. Brain Res. 2009, 1289:79-84.
    • (2009) Brain Res. , vol.1289 , pp. 79-84
    • Schilling, M.1    Strecker, J.K.2    Ringelstein, E.B.3    Schabitz, W.R.4    Kiefer, R.5
  • 270
    • 18844415609 scopus 로고    scopus 로고
    • Spinal cord injury induces early and persistent lesional P2X4 receptor expression
    • Schwab J.M., Guo L., Schluesener H.J. Spinal cord injury induces early and persistent lesional P2X4 receptor expression. J. Neuroimmunol. 2005, 163:185-189.
    • (2005) J. Neuroimmunol. , vol.163 , pp. 185-189
    • Schwab, J.M.1    Guo, L.2    Schluesener, H.J.3
  • 271
    • 0029900303 scopus 로고    scopus 로고
    • Degeneration and regeneration of axons in the lesioned spinal cord
    • Schwab M.E., Bartholdi D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol. Rev. 1996, 76:319-370.
    • (1996) Physiol. Rev. , vol.76 , pp. 319-370
    • Schwab, M.E.1    Bartholdi, D.2
  • 272
    • 33645902493 scopus 로고    scopus 로고
    • Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
    • Serbina N.V., Pamer E.G. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat. Immunol. 2006, 7:311-317.
    • (2006) Nat. Immunol. , vol.7 , pp. 311-317
    • Serbina, N.V.1    Pamer, E.G.2
  • 273
    • 9644307970 scopus 로고    scopus 로고
    • Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia
    • Sessa G., Podini P., Mariani M., Meroni A., Spreafico R., Sinigaglia F., Colonna M., Panina P., Meldolesi J. Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia. Eur. J. Neurosci. 2004, 20:2617-2628.
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 2617-2628
    • Sessa, G.1    Podini, P.2    Mariani, M.3    Meroni, A.4    Spreafico, R.5    Sinigaglia, F.6    Colonna, M.7    Panina, P.8    Meldolesi, J.9
  • 275
    • 84860468574 scopus 로고    scopus 로고
    • AGEs-RAGE mediated up-regulation of connexin43 in activated human microglial CHME-5 cells
    • Shaikh S.B., Uy B., Perera A., Nicholson L.F. AGEs-RAGE mediated up-regulation of connexin43 in activated human microglial CHME-5 cells. Neurochem. Int. 2012, 60:640-651.
    • (2012) Neurochem. Int. , vol.60 , pp. 640-651
    • Shaikh, S.B.1    Uy, B.2    Perera, A.3    Nicholson, L.F.4
  • 276
    • 33847108114 scopus 로고    scopus 로고
    • Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice
    • Sheehan J.J., Zhou C., Gravanis I., Rogove A.D., Wu Y.P., Bogenhagen D.F., Tsirka S.E. Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice. J. Neurosci. 2007, 27:1738-1745.
    • (2007) J. Neurosci. , vol.27 , pp. 1738-1745
    • Sheehan, J.J.1    Zhou, C.2    Gravanis, I.3    Rogove, A.D.4    Wu, Y.P.5    Bogenhagen, D.F.6    Tsirka, S.E.7
  • 277
    • 33744942373 scopus 로고    scopus 로고
    • CCL5 evokes calcium signals in microglia through a kinase-, phosphoinositide-, and nucleotide-dependent mechanism
    • Shideman C.R., Hu S., Peterson P.K., Thayer S.A. CCL5 evokes calcium signals in microglia through a kinase-, phosphoinositide-, and nucleotide-dependent mechanism. J. Neurosci. Res. 2006, 83:1471-1484.
    • (2006) J. Neurosci. Res. , vol.83 , pp. 1471-1484
    • Shideman, C.R.1    Hu, S.2    Peterson, P.K.3    Thayer, S.A.4
  • 278
    • 0031976833 scopus 로고    scopus 로고
    • Chemokine receptor utilization by human immunodeficiency virus type 1 isolates that replicate in microglia
    • Shieh J.T., Albright A.V., Sharron M., Gartner S., Strizki J., Doms R.W., Gonzalez-Scarano F. Chemokine receptor utilization by human immunodeficiency virus type 1 isolates that replicate in microglia. J. Virol. 1998, 72:4243-4249.
    • (1998) J. Virol. , vol.72 , pp. 4243-4249
    • Shieh, J.T.1    Albright, A.V.2    Sharron, M.3    Gartner, S.4    Strizki, J.5    Doms, R.W.6    Gonzalez-Scarano, F.7
  • 279
    • 77954325416 scopus 로고    scopus 로고
    • P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways
    • Shiratori M., Tozaki-Saitoh H., Yoshitake M., Tsuda M., Inoue K. P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways. J. Neurochem. 2010, 114:810-819.
    • (2010) J. Neurochem. , vol.114 , pp. 810-819
    • Shiratori, M.1    Tozaki-Saitoh, H.2    Yoshitake, M.3    Tsuda, M.4    Inoue, K.5
  • 280
    • 84869162083 scopus 로고    scopus 로고
    • Animal models for studying microglia: the first, the popular, and the new
    • Sieger D., Peri F. Animal models for studying microglia: the first, the popular, and the new. Glia 2013, 61:3-9.
    • (2013) Glia , vol.61 , pp. 3-9
    • Sieger, D.1    Peri, F.2
  • 281
    • 79955823910 scopus 로고    scopus 로고
    • Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina
    • Sivakumar V., Foulds W.S., Luu C.D., Ling E.A., Kaur C. Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina. J. Pathol. 2011, 224:245-260.
    • (2011) J. Pathol. , vol.224 , pp. 245-260
    • Sivakumar, V.1    Foulds, W.S.2    Luu, C.D.3    Ling, E.A.4    Kaur, C.5
  • 283
    • 0141456120 scopus 로고    scopus 로고
    • CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase
    • Smit M.J., Verdijk P., van der Raaij-Helmer E.M., Navis M., Hensbergen P.J., Leurs R., Tensen C.P. CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase. Blood 2003, 102:1959-1965.
    • (2003) Blood , vol.102 , pp. 1959-1965
    • Smit, M.J.1    Verdijk, P.2    van der Raaij-Helmer, E.M.3    Navis, M.4    Hensbergen, P.J.5    Leurs, R.6    Tensen, C.P.7
  • 284
    • 0036707529 scopus 로고    scopus 로고
    • Fcgamma receptor I- and III-mediated macrophage inflammatory protein 1alpha induction in primary human and murine microglia
    • Song X., Shapiro S., Goldman D.L., Casadevall A., Scharff M., Lee S.C. Fcgamma receptor I- and III-mediated macrophage inflammatory protein 1alpha induction in primary human and murine microglia. Infect. Immun. 2002, 70:5177-5184.
    • (2002) Infect. Immun. , vol.70 , pp. 5177-5184
    • Song, X.1    Shapiro, S.2    Goldman, D.L.3    Casadevall, A.4    Scharff, M.5    Lee, S.C.6
  • 285
    • 2642518949 scopus 로고    scopus 로고
    • Fcgamma receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction
    • Song X., Tanaka S., Cox D., Lee S.C. Fcgamma receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction. J. Leukoc. Biol. 2004, 75:1147-1155.
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 1147-1155
    • Song, X.1    Tanaka, S.2    Cox, D.3    Lee, S.C.4
  • 289
    • 84890152999 scopus 로고    scopus 로고
    • Activated microglia in a rat stroke model express NG2 proteoglycan in peri-infarct tissue through the involvement of TGF-beta1
    • Sugimoto K., Nishioka R., Ikeda A., Mise A., Takahashi H., Yano H., Kumon Y., Ohnishi T., Tanaka J. Activated microglia in a rat stroke model express NG2 proteoglycan in peri-infarct tissue through the involvement of TGF-beta1. Glia 2014, 62:185-198.
    • (2014) Glia , vol.62 , pp. 185-198
    • Sugimoto, K.1    Nishioka, R.2    Ikeda, A.3    Mise, A.4    Takahashi, H.5    Yano, H.6    Kumon, Y.7    Ohnishi, T.8    Tanaka, J.9
  • 290
    • 78650172970 scopus 로고    scopus 로고
    • Calcium-dependent phospholipid scrambling by TMEM16F
    • Suzuki J., Umeda M., Sims P.J., Nagata S. Calcium-dependent phospholipid scrambling by TMEM16F. Nature 2010, 468:834-838.
    • (2010) Nature , vol.468 , pp. 834-838
    • Suzuki, J.1    Umeda, M.2    Sims, P.J.3    Nagata, S.4
  • 291
    • 77951909169 scopus 로고    scopus 로고
    • Differential recruitment of activating and inhibitory Fc gamma RII during phagocytosis
    • Syam S., Mero P., Pham T., McIntosh C.A., Bruhns P., Booth J.W. Differential recruitment of activating and inhibitory Fc gamma RII during phagocytosis. J. Immunol. 2010, 184:2966-2973.
    • (2010) J. Immunol. , vol.184 , pp. 2966-2973
    • Syam, S.1    Mero, P.2    Pham, T.3    McIntosh, C.A.4    Bruhns, P.5    Booth, J.W.6
  • 292
    • 14244268775 scopus 로고    scopus 로고
    • Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
    • Takahashi K., Rochford C.D., Neumann H. Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. J. Exp. Med. 2005, 201:647-657.
    • (2005) J. Exp. Med. , vol.201 , pp. 647-657
    • Takahashi, K.1    Rochford, C.D.2    Neumann, H.3
  • 294
    • 50949128076 scopus 로고    scopus 로고
    • Lysophospholipids and ATP mutually suppress maturation and release of IL-1 beta in mouse microglial cells using a Rho-dependent pathway
    • Takenouchi T., Iwamaru Y., Sugama S., Sato M., Hashimoto M., Kitani H. Lysophospholipids and ATP mutually suppress maturation and release of IL-1 beta in mouse microglial cells using a Rho-dependent pathway. J. Immunol. 2008, 180:7827-7839.
    • (2008) J. Immunol. , vol.180 , pp. 7827-7839
    • Takenouchi, T.1    Iwamaru, Y.2    Sugama, S.3    Sato, M.4    Hashimoto, M.5    Kitani, H.6
  • 295
    • 34250220190 scopus 로고    scopus 로고
    • Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells
    • Takenouchi T., Sato M., Kitani H. Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells. J. Neurochem. 2007, 102:1518-1532.
    • (2007) J. Neurochem. , vol.102 , pp. 1518-1532
    • Takenouchi, T.1    Sato, M.2    Kitani, H.3
  • 296
    • 69149106095 scopus 로고    scopus 로고
    • Modulation of the ATP-lnduced release and processing of IL-1beta in microglial cells
    • Takenouchi T., Sugama S., Iwamaru Y., Hashimoto M., Kitani H. Modulation of the ATP-lnduced release and processing of IL-1beta in microglial cells. Crit. Rev. Immunol. 2009, 29:335-345.
    • (2009) Crit. Rev. Immunol. , vol.29 , pp. 335-345
    • Takenouchi, T.1    Sugama, S.2    Iwamaru, Y.3    Hashimoto, M.4    Kitani, H.5
  • 299
    • 0031016575 scopus 로고    scopus 로고
    • Differential activation of the tyrosine kinases ZAP-70 and Syk after Fc gamma RI stimulation
    • Taylor N., Jahn T., Smith S., Lamkin T., Uribe L., Liu Y., Durden D.L., Weinberg K. Differential activation of the tyrosine kinases ZAP-70 and Syk after Fc gamma RI stimulation. Blood 1997, 89:388-396.
    • (1997) Blood , vol.89 , pp. 388-396
    • Taylor, N.1    Jahn, T.2    Smith, S.3    Lamkin, T.4    Uribe, L.5    Liu, Y.6    Durden, D.L.7    Weinberg, K.8
  • 300
    • 15444378502 scopus 로고    scopus 로고
    • (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists
    • Tchilibon S., Joshi B.V., Kim S.K., Duong H.T., Gao Z.G., Jacobson K.A. (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. J. Med. Chem. 2005, 48:1745-1758.
    • (2005) J. Med. Chem. , vol.48 , pp. 1745-1758
    • Tchilibon, S.1    Joshi, B.V.2    Kim, S.K.3    Duong, H.T.4    Gao, Z.G.5    Jacobson, K.A.6
  • 303
    • 58149459143 scopus 로고    scopus 로고
    • Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease
    • Thrash J.C., Torbett B.E., Carson M.J. Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease. Neurochem. Res. 2009, 34:38-45.
    • (2009) Neurochem. Res. , vol.34 , pp. 38-45
    • Thrash, J.C.1    Torbett, B.E.2    Carson, M.J.3
  • 307
    • 37349124567 scopus 로고    scopus 로고
    • Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain
    • Trincavelli M.L., Melani A., Guidi S., Cuboni S., Cipriani S., Pedata F., Martini C. Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain. J. Neurochem. 2008, 104:479-490.
    • (2008) J. Neurochem. , vol.104 , pp. 479-490
    • Trincavelli, M.L.1    Melani, A.2    Guidi, S.3    Cuboni, S.4    Cipriani, S.5    Pedata, F.6    Martini, C.7
  • 308
    • 33847183077 scopus 로고    scopus 로고
    • Cooperation of Toll-like receptor signals in innate immune defence
    • Trinchieri G., Sher A. Cooperation of Toll-like receptor signals in innate immune defence. Nat. Rev. Immunol. 2007, 7:179-190.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 179-190
    • Trinchieri, G.1    Sher, A.2
  • 310
    • 34147164049 scopus 로고    scopus 로고
    • Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites
    • Tsou C.L., Peters W., Si Y., Slaymaker S., Aslanian A.M., Weisberg S.P., Mack M., Charo I.F. Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J. Clin. Invest. 2007, 117:902-909.
    • (2007) J. Clin. Invest. , vol.117 , pp. 902-909
    • Tsou, C.L.1    Peters, W.2    Si, Y.3    Slaymaker, S.4    Aslanian, A.M.5    Weisberg, S.P.6    Mack, M.7    Charo, I.F.8
  • 313
    • 44949248511 scopus 로고    scopus 로고
    • Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury
    • Tsuda M., Toyomitsu E., Komatsu T., Masuda T., Kunifusa E., Nasu-Tada K., Koizumi S., Yamamoto K., Ando J., Inoue K. Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury. Glia 2008, 56:579-585.
    • (2008) Glia , vol.56 , pp. 579-585
    • Tsuda, M.1    Toyomitsu, E.2    Komatsu, T.3    Masuda, T.4    Kunifusa, E.5    Nasu-Tada, K.6    Koizumi, S.7    Yamamoto, K.8    Ando, J.9    Inoue, K.10
  • 314
    • 77449099299 scopus 로고    scopus 로고
    • Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways
    • Tsuda M., Toyomitsu E., Kometani M., Tozaki-Saitoh H., Inoue K. Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways. J. Cell. Mol. Med. 2009, 13:3251-3259.
    • (2009) J. Cell. Mol. Med. , vol.13 , pp. 3251-3259
    • Tsuda, M.1    Toyomitsu, E.2    Kometani, M.3    Tozaki-Saitoh, H.4    Inoue, K.5
  • 315
    • 36448966388 scopus 로고    scopus 로고
    • Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury
    • Tsuda M., Tozaki-Saitoh H., Masuda T., Toyomitsu E., Tezuka T., Yamamoto T., Inoue K. Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury. Glia 2008, 56:50-58.
    • (2008) Glia , vol.56 , pp. 50-58
    • Tsuda, M.1    Tozaki-Saitoh, H.2    Masuda, T.3    Toyomitsu, E.4    Tezuka, T.5    Yamamoto, T.6    Inoue, K.7
  • 319
    • 0028009224 scopus 로고
    • Fc receptors for IgG on cultured human microglia mediate cytotoxicity and phagocytosis of antibody-coated targets
    • Ulvestad E., Williams K., Matre R., Nyland H., Olivier A., Antel J. Fc receptors for IgG on cultured human microglia mediate cytotoxicity and phagocytosis of antibody-coated targets. J. Neuropathol. Exp. Neurol. 1994, 53:27-36.
    • (1994) J. Neuropathol. Exp. Neurol. , vol.53 , pp. 27-36
    • Ulvestad, E.1    Williams, K.2    Matre, R.3    Nyland, H.4    Olivier, A.5    Antel, J.6
  • 321
  • 322
    • 34247565506 scopus 로고    scopus 로고
    • Glycan-based interactions involving vertebrate sialic-acid-recognizing proteins
    • Varki A. Glycan-based interactions involving vertebrate sialic-acid-recognizing proteins. Nature 2007, 446:1023-1029.
    • (2007) Nature , vol.446 , pp. 1023-1029
    • Varki, A.1
  • 324
    • 0030882883 scopus 로고    scopus 로고
    • Nasu-Hakola syndrome: polycystic lipomembranous osteodysplasia with sclerosing leucoencephalopathy and presenile dementia
    • Verloes A., Maquet P., Sadzot B., Vivario M., Thiry A., Franck G. Nasu-Hakola syndrome: polycystic lipomembranous osteodysplasia with sclerosing leucoencephalopathy and presenile dementia. J. Med. Genet. 1997, 34:753-757.
    • (1997) J. Med. Genet. , vol.34 , pp. 753-757
    • Verloes, A.1    Maquet, P.2    Sadzot, B.3    Vivario, M.4    Thiry, A.5    Franck, G.6
  • 325
    • 43049173715 scopus 로고    scopus 로고
    • Hypoxia enhances CXCR4 expression favoring microglia migration via HIF-1alpha activation
    • Wang X., Li C., Chen Y., Hao Y., Zhou W., Chen C., Yu Z. Hypoxia enhances CXCR4 expression favoring microglia migration via HIF-1alpha activation. Biochem. Biophys. Res. Commun. 2008, 371:283-288.
    • (2008) Biochem. Biophys. Res. Commun. , vol.371 , pp. 283-288
    • Wang, X.1    Li, C.2    Chen, Y.3    Hao, Y.4    Zhou, W.5    Chen, C.6    Yu, Z.7
  • 326
    • 84863167179 scopus 로고    scopus 로고
    • Roles of chemokine CXCL12 and its receptors in ischemic stroke
    • Wang Y., Huang J., Li Y., Yang G.Y. Roles of chemokine CXCL12 and its receptors in ischemic stroke. Curr. Drug Targets 2012, 13:166-172.
    • (2012) Curr. Drug Targets , vol.13 , pp. 166-172
    • Wang, Y.1    Huang, J.2    Li, Y.3    Yang, G.Y.4
  • 327
    • 80052481793 scopus 로고    scopus 로고
    • The association of L-selectin polymorphisms with L-selectin serum levels and risk of ischemic stroke
    • Wei Y.S., Lan Y., Meng L.Q., Nong L.G. The association of L-selectin polymorphisms with L-selectin serum levels and risk of ischemic stroke. J. Thromb. Thrombolysis 2011, 32:110-115.
    • (2011) J. Thromb. Thrombolysis , vol.32 , pp. 110-115
    • Wei, Y.S.1    Lan, Y.2    Meng, L.Q.3    Nong, L.G.4
  • 328
    • 79955836709 scopus 로고    scopus 로고
    • Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis
    • Weinger J.G., Brosnan C.F., Loudig O., Goldberg M.F., Macian F., Arnett H.A., Prieto A.L., Tsiperson V., Shafit-Zagardo B. Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis. J. Neuroinflammation 2011, 8:49.
    • (2011) J. Neuroinflammation , vol.8 , pp. 49
    • Weinger, J.G.1    Brosnan, C.F.2    Loudig, O.3    Goldberg, M.F.4    Macian, F.5    Arnett, H.A.6    Prieto, A.L.7    Tsiperson, V.8    Shafit-Zagardo, B.9
  • 329
    • 33746377015 scopus 로고    scopus 로고
    • Fibrillar beta-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia
    • Wilkinson B., Koenigsknecht-Talboo J., Grommes C., Lee C.Y., Landreth G. Fibrillar beta-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia. J. Biol. Chem. 2006, 281:20842-20850.
    • (2006) J. Biol. Chem. , vol.281 , pp. 20842-20850
    • Wilkinson, B.1    Koenigsknecht-Talboo, J.2    Grommes, C.3    Lee, C.Y.4    Landreth, G.5
  • 330
    • 2542421699 scopus 로고    scopus 로고
    • Adenosine A3 receptor-induced CCL2 synthesis in cultured mouse astrocytes
    • Wittendorp M.C., Boddeke H.W., Biber K. Adenosine A3 receptor-induced CCL2 synthesis in cultured mouse astrocytes. Glia 2004, 46:410-418.
    • (2004) Glia , vol.46 , pp. 410-418
    • Wittendorp, M.C.1    Boddeke, H.W.2    Biber, K.3
  • 331
    • 0033836217 scopus 로고    scopus 로고
    • Phagocytic clearance of apoptotic neurons by Microglia/Brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition
    • Witting A., Muller P., Herrmann A., Kettenmann H., Nolte C. Phagocytic clearance of apoptotic neurons by Microglia/Brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition. J. Neurochem. 2000, 75:1060-1070.
    • (2000) J. Neurochem. , vol.75 , pp. 1060-1070
    • Witting, A.1    Muller, P.2    Herrmann, A.3    Kettenmann, H.4    Nolte, C.5
  • 332
    • 67649884746 scopus 로고    scopus 로고
    • Delayed P2X4R expression after hypoxia-ischemia is associated with microglia in the immature rat brain
    • Wixey J.A., Reinebrant H.E., Carty M.L., Buller K.M. Delayed P2X4R expression after hypoxia-ischemia is associated with microglia in the immature rat brain. J. Neuroimmunol. 2009, 212:35-43.
    • (2009) J. Neuroimmunol. , vol.212 , pp. 35-43
    • Wixey, J.A.1    Reinebrant, H.E.2    Carty, M.L.3    Buller, K.M.4
  • 334
    • 84880626992 scopus 로고    scopus 로고
    • Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation
    • Wong W.T. Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation. Front. Cell. Neurosci. 2013, 7:22.
    • (2013) Front. Cell. Neurosci. , vol.7 , pp. 22
    • Wong, W.T.1
  • 336
    • 0033681191 scopus 로고    scopus 로고
    • Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function
    • Wright G.J., Puklavec M.J., Willis A.C., Hoek R.M., Sedgwick J.D., Brown M.H., Barclay A.N. Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function. Immunity 2000, 13:233-242.
    • (2000) Immunity , vol.13 , pp. 233-242
    • Wright, G.J.1    Puklavec, M.J.2    Willis, A.C.3    Hoek, R.M.4    Sedgwick, J.D.5    Brown, M.H.6    Barclay, A.N.7
  • 337
    • 78650994912 scopus 로고    scopus 로고
    • Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge
    • Wynne A.M., Henry C.J., Huang Y., Cleland A., Godbout J.P. Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge. Brain Behav. Immun. 2010, 24:1190-1201.
    • (2010) Brain Behav. Immun. , vol.24 , pp. 1190-1201
    • Wynne, A.M.1    Henry, C.J.2    Huang, Y.3    Cleland, A.4    Godbout, J.P.5
  • 338
    • 79951525437 scopus 로고    scopus 로고
    • Ct3d: tracking microglia motility in 3D using a novel cosegmentation approach
    • Xiao H., Li Y., Du J., Mosig A. Ct3d: tracking microglia motility in 3D using a novel cosegmentation approach. Bioinformatics 2011, 27:564-571.
    • (2011) Bioinformatics , vol.27 , pp. 564-571
    • Xiao, H.1    Li, Y.2    Du, J.3    Mosig, A.4
  • 340
    • 77954703072 scopus 로고    scopus 로고
    • Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration
    • Yao H., Yang Y., Kim K.J., Bethel-Brown C., Gong N., Funa K., Gendelman H.E., Su T.P., Wang J.Q., Buch S. Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. Blood 2010, 115:4951-4962.
    • (2010) Blood , vol.115 , pp. 4951-4962
    • Yao, H.1    Yang, Y.2    Kim, K.J.3    Bethel-Brown, C.4    Gong, N.5    Funa, K.6    Gendelman, H.E.7    Su, T.P.8    Wang, J.Q.9    Buch, S.10
  • 341
    • 77957807665 scopus 로고    scopus 로고
    • The C terminus of mouse monocyte chemoattractant protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency
    • Yao Y., Tsirka S.E. The C terminus of mouse monocyte chemoattractant protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency. J. Biol. Chem. 2010, 285:31509-31516.
    • (2010) J. Biol. Chem. , vol.285 , pp. 31509-31516
    • Yao, Y.1    Tsirka, S.E.2
  • 342
    • 84859704700 scopus 로고    scopus 로고
    • The CCL2-CCR2 system affects the progression and clearance of intracerebral hemorrhage
    • Yao Y., Tsirka S.E. The CCL2-CCR2 system affects the progression and clearance of intracerebral hemorrhage. Glia 2012, 60:908-918.
    • (2012) Glia , vol.60 , pp. 908-918
    • Yao, Y.1    Tsirka, S.E.2
  • 343
    • 7044247188 scopus 로고    scopus 로고
    • Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury
    • Yu L., Huang Z., Mariani J., Wang Y., Moskowitz M., Chen J.F. Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury. Nat. Med. 2004, 10:1081-1087.
    • (2004) Nat. Med. , vol.10 , pp. 1081-1087
    • Yu, L.1    Huang, Z.2    Mariani, J.3    Wang, Y.4    Moskowitz, M.5    Chen, J.F.6
  • 344
    • 84865501312 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 alpha (SDF-1alpha) improves neural recovery after spinal cord contusion in rats
    • Zendedel A., Nobakht M., Bakhtiyari M., Beyer C., Kipp M., Baazm M., Joghataie M.T. Stromal cell-derived factor-1 alpha (SDF-1alpha) improves neural recovery after spinal cord contusion in rats. Brain Res. 2012, 1473:214-226.
    • (2012) Brain Res. , vol.1473 , pp. 214-226
    • Zendedel, A.1    Nobakht, M.2    Bakhtiyari, M.3    Beyer, C.4    Kipp, M.5    Baazm, M.6    Joghataie, M.T.7
  • 345
    • 36048991728 scopus 로고    scopus 로고
    • Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain
    • Zhang J., Shi X.Q., Echeverry S., Mogil J.S., De Koninck Y., Rivest S. Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain. J. Neurosci. 2007, 27:12396-12406.
    • (2007) J. Neurosci. , vol.27 , pp. 12396-12406
    • Zhang, J.1    Shi, X.Q.2    Echeverry, S.3    Mogil, J.S.4    De Koninck, Y.5    Rivest, S.6
  • 346
    • 78751700661 scopus 로고    scopus 로고
    • S100B attenuates microglia activation in gliomas: possible role of STAT3 pathway
    • Zhang L., Liu W., Alizadeh D., Zhao D., Farrukh O., Lin J., Badie S.A., Badie B. S100B attenuates microglia activation in gliomas: possible role of STAT3 pathway. Glia 2011, 59:486-498.
    • (2011) Glia , vol.59 , pp. 486-498
    • Zhang, L.1    Liu, W.2    Alizadeh, D.3    Zhao, D.4    Farrukh, O.5    Lin, J.6    Badie, S.A.7    Badie, B.8
  • 347
    • 9144224962 scopus 로고    scopus 로고
    • Molecular mechanisms of CD200 inhibition of mast cell activation
    • Zhang S., Cherwinski H., Sedgwick J.D., Phillips J.H. Molecular mechanisms of CD200 inhibition of mast cell activation. J. Immunol. 2004, 173:6786-6793.
    • (2004) J. Immunol. , vol.173 , pp. 6786-6793
    • Zhang, S.1    Cherwinski, H.2    Sedgwick, J.D.3    Phillips, J.H.4
  • 348
    • 33646460670 scopus 로고    scopus 로고
    • Identification of tyrosine residues crucial for CD200R-mediated inhibition of mast cell activation
    • Zhang S., Phillips J.H. Identification of tyrosine residues crucial for CD200R-mediated inhibition of mast cell activation. J. Leukoc. Biol. 2006, 79:363-368.
    • (2006) J. Leukoc. Biol. , vol.79 , pp. 363-368
    • Zhang, S.1    Phillips, J.H.2
  • 349
    • 80355125158 scopus 로고    scopus 로고
    • CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease
    • Zhang S., Wang X.J., Tian L.P., Pan J., Lu G.Q., Zhang Y.J., Ding J.Q., Chen S.D. CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease. J. Neuroinflammation 2011, 8:154.
    • (2011) J. Neuroinflammation , vol.8 , pp. 154
    • Zhang, S.1    Wang, X.J.2    Tian, L.P.3    Pan, J.4    Lu, G.Q.5    Zhang, Y.J.6    Ding, J.Q.7    Chen, S.D.8
  • 350
    • 62949163677 scopus 로고    scopus 로고
    • Hematoma resolution as a therapeutic target: the role of microglia/macrophages
    • Zhao X., Grotta J., Gonzales N., Aronowski J. Hematoma resolution as a therapeutic target: the role of microglia/macrophages. Stroke 2009, 40:S92-S94.
    • (2009) Stroke , vol.40
    • Zhao, X.1    Grotta, J.2    Gonzales, N.3    Aronowski, J.4
  • 351
    • 34247560648 scopus 로고    scopus 로고
    • Hematoma resolution as a target for intracerebral hemorrhage treatment: role for peroxisome proliferator-activated receptor gamma in microglia/macrophages
    • Zhao X., Sun G., Zhang J., Strong R., Song W., Gonzales N., Grotta J.C., Aronowski J. Hematoma resolution as a target for intracerebral hemorrhage treatment: role for peroxisome proliferator-activated receptor gamma in microglia/macrophages. Ann. Neurol. 2007, 61:352-362.
    • (2007) Ann. Neurol. , vol.61 , pp. 352-362
    • Zhao, X.1    Sun, G.2    Zhang, J.3    Strong, R.4    Song, W.5    Gonzales, N.6    Grotta, J.C.7    Aronowski, J.8
  • 352
    • 34249717859 scopus 로고    scopus 로고
    • Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine
    • Zhuang Z.Y., Kawasaki Y., Tan P.H., Wen Y.R., Huang J., Ji R.R. Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav. Immun. 2007, 21:642-651.
    • (2007) Brain Behav. Immun. , vol.21 , pp. 642-651
    • Zhuang, Z.Y.1    Kawasaki, Y.2    Tan, P.H.3    Wen, Y.R.4    Huang, J.5    Ji, R.R.6
  • 353
    • 0032507962 scopus 로고    scopus 로고
    • Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
    • Zou Y.R., Kottmann A.H., Kuroda M., Taniuchi I., Littman D.R. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 1998, 393:595-599.
    • (1998) Nature , vol.393 , pp. 595-599
    • Zou, Y.R.1    Kottmann, A.H.2    Kuroda, M.3    Taniuchi, I.4    Littman, D.R.5


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