-
1
-
-
84908147740
-
Bedside to bench in juvenile myelomonocytic leukemia: Insights into leukemogenesis from a rare pediatric leukemia
-
Chang, T.Y., Dvorak, C.C., & Loh, M.L. Bedside to bench in juvenile myelomonocytic leukemia: insights into leukemogenesis from a rare pediatric leukemia. Blood 124, 2487-2497 (2014).
-
(2014)
Blood
, vol.124
, pp. 2487-2497
-
-
Chang, T.Y.1
Dvorak, C.C.2
Loh, M.L.3
-
2
-
-
84906076393
-
Juvenile myelomonocytic leukemia: Molecular pathogenesis informs current approaches to therapy and hematopoietic cell transplantation
-
Dvorak, C.C., & Loh, M.L. Juvenile myelomonocytic leukemia: molecular pathogenesis informs current approaches to therapy and hematopoietic cell transplantation. Front. Pediatr. 2, 25 (2014).
-
(2014)
Front. Pediatr.
, vol.2
, pp. 25
-
-
Dvorak, C.C.1
Loh, M.L.2
-
3
-
-
34250017142
-
Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations
-
Matsuda, K., et al. Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. Blood 109, 5477-5480 (2007).
-
(2007)
Blood
, vol.109
, pp. 5477-5480
-
-
Matsuda, K.1
-
4
-
-
77955913794
-
Long-Derm survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations
-
Matsuda, K., et al. Long-Derm survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations. Blood 115, 5429-5431 (2010).
-
(2010)
Blood
, vol.115
, pp. 5429-5431
-
-
Matsuda, K.1
-
5
-
-
77951644021
-
Gene expression-based classification as an independent predictor of clinical outcome in juvenile myelomonocytic leukemia
-
Bresolin, S., et al. Gene expression-based classification as an independent predictor of clinical outcome in juvenile myelomonocytic leukemia. J. Clin. Oncol. 28, 1919-1927 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1919-1927
-
-
Bresolin, S.1
-
6
-
-
38349111411
-
Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations
-
author reply 967-968
-
Flotho, C., et al. Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations. Blood 111, 966-967, author reply 967-968 (2008).
-
(2008)
Blood
, vol.111
, pp. 966-967
-
-
Flotho, C.1
-
7
-
-
0030947237
-
Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders
-
Side, L., et al. Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders. N. Engl. J. Med. 336, 1713-1720 (1997).
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1713-1720
-
-
Side, L.1
-
8
-
-
0032896457
-
RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML)
-
Flotho, C., et al. RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML). Leukemia 13, 32-37 (1999).
-
(1999)
Leukemia
, vol.13
, pp. 32-37
-
-
Flotho, C.1
-
9
-
-
0038278866
-
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
-
Tartaglia, M., et al. Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia. Nat. Genet. 34, 148-150 (2003).
-
(2003)
Nat. Genet.
, vol.34
, pp. 148-150
-
-
Tartaglia, M.1
-
10
-
-
12144286410
-
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis
-
Loh, M.L., et al. Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis. Blood 103, 2325-2331 (2004).
-
(2004)
Blood
, vol.103
, pp. 2325-2331
-
-
Loh, M.L.1
-
11
-
-
70349249988
-
Mutations in CBL occur frequently in juvenile myelomonocytic leukemia
-
Loh, M.L., et al. Mutations in CBL occur frequently in juvenile myelomonocytic leukemia. Blood 114, 1859-1863 (2009).
-
(2009)
Blood
, vol.114
, pp. 1859-1863
-
-
Loh, M.L.1
-
12
-
-
84881020319
-
Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia
-
Sakaguchi, H., et al. Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia. Nat. Genet. 45, 937-941 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 937-941
-
-
Sakaguchi, H.1
-
13
-
-
84926688835
-
Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia
-
Stieglitz, E., et al. Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia. Blood 125, 516-524 (2015).
-
(2015)
Blood
, vol.125
, pp. 516-524
-
-
Stieglitz, E.1
-
14
-
-
84984935016
-
Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia
-
Niemeyer, C.M., et al. Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia. Nat. Genet. 42, 794-800 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 794-800
-
-
Niemeyer, C.M.1
-
15
-
-
33747815415
-
Interstitial uniparental isodisomy at clustered breakpoint intervals is a frequent mechanism of NF1 inactivation in myeloid malignancies
-
Stephens, K., et al. Interstitial uniparental isodisomy at clustered breakpoint intervals is a frequent mechanism of NF1 inactivation in myeloid malignancies. Blood 108, 1684-1689 (2006).
-
(2006)
Blood
, vol.108
, pp. 1684-1689
-
-
Stephens, K.1
-
16
-
-
84904763680
-
Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis
-
Flex, E., et al. Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis. Hum. Mol. Genet. 23, 4315-4327 (2014).
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 4315-4327
-
-
Flex, E.1
-
17
-
-
0033602360
-
TC21 and Ras share indistinguishable transforming and differentiating activities
-
Graham, S.M., et al. TC21 and Ras share indistinguishable transforming and differentiating activities. Oncogene 18, 2107-2116 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 2107-2116
-
-
Graham, S.M.1
-
18
-
-
84867507362
-
In vivo regulation of TGF-b by R-Ras2 revealed through loss of the RasGAP protein NF1
-
Patmore, D.M., et al. In vivo regulation of TGF-b by R-Ras2 revealed through loss of the RasGAP protein NF1. Cancer Res. 72, 5317-5327 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 5317-5327
-
-
Patmore, D.M.1
-
19
-
-
0028136688
-
A human oncogene of the RAS superfamily unmasked by expression cDNA cloning
-
Chan, A.M., Miki, T., Meyers, K.A., & Aaronson, S.A. A human oncogene of the RAS superfamily unmasked by expression cDNA cloning. Proc. Natl. Acad. Sci. USA 91, 7558-7562 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7558-7562
-
-
Chan, A.M.1
Miki, T.2
Meyers, K.A.3
Aaronson, S.A.4
-
20
-
-
84923301480
-
How i treat juvenile myelomonocytic leukemia (JMML)
-
Locatelli, F., & Niemeyer, C.M. How I treat juvenile myelomonocytic leukemia (JMML). Blood 125, 1083-1090 (2015).
-
(2015)
Blood
, vol.125
, pp. 1083-1090
-
-
Locatelli, F.1
Niemeyer, C.M.2
-
21
-
-
0034080551
-
Segmental neurofibromatosis is caused by somatic mutation of the neurofibromatosis type 1 (NF1) gene
-
Tinschert, S., et al. Segmental neurofibromatosis is caused by somatic mutation of the neurofibromatosis type 1 (NF1) gene. Eur. J. Hum. Genet. 8, 455-459 (2000).
-
(2000)
Eur. J. Hum. Genet.
, vol.8
, pp. 455-459
-
-
Tinschert, S.1
-
22
-
-
0032125716
-
Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1
-
Side, L.E., et al. Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1. Blood 92, 267-272 (1998).
-
(1998)
Blood
, vol.92
, pp. 267-272
-
-
Side, L.E.1
-
23
-
-
52949129499
-
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates
-
Kotecha, N., et al. Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell 14, 335-343 (2008).
-
(2008)
Cancer Cell
, vol.14
, pp. 335-343
-
-
Kotecha, N.1
-
24
-
-
0035811366
-
Lnk adaptor: Novel negative regulator of B cell lymphopoiesis
-
Rudd, C.E. Lnk adaptor: novel negative regulator of B cell lymphopoiesis. Sci. STKE 2001, pe1 (2001).
-
(2001)
Sci. STKE
, vol.2001
, pp. pe1
-
-
Rudd, C.E.1
-
25
-
-
77953485892
-
Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
-
Oh, S.T., et al. Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. Blood 116, 988-992 (2010).
-
(2010)
Blood
, vol.116
, pp. 988-992
-
-
Oh, S.T.1
-
26
-
-
77956670899
-
LNK mutations in JAK2 mutation-negative erythrocytosis
-
Lasho, T.L., Pardanani, A., & Tefferi, A. LNK mutations in JAK2 mutation-negative erythrocytosis. N. Engl. J. Med. 363, 1189-1190 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1189-1190
-
-
Lasho, T.L.1
Pardanani, A.2
Tefferi, A.3
-
27
-
-
80053969987
-
LNK can also be mutated outside PH and SH2 domains in myeloproliferative neoplasms with and without V617FJAK2 mutation
-
Hurtado, C., et al. LNK can also be mutated outside PH and SH2 domains in myeloproliferative neoplasms with and without V617FJAK2 mutation. Leuk. Res. 35, 1537-1539 (2011).
-
(2011)
Leuk. Res.
, vol.35
, pp. 1537-1539
-
-
Hurtado, C.1
-
28
-
-
84887805156
-
Genetic loss of SH2B3 in acute lymphoblastic leukemia
-
Perez-Garcia, A., et al. Genetic loss of SH2B3 in acute lymphoblastic leukemia. Blood 122, 2425-2432 (2013).
-
(2013)
Blood
, vol.122
, pp. 2425-2432
-
-
Perez-Garcia, A.1
-
29
-
-
80054033431
-
A nonsynonymous LNK polymorphism associated with idiopathic erythrocytosis
-
McMullin, M.F., Wu, C., Percy, M.J., & Tong, W. A nonsynonymous LNK polymorphism associated with idiopathic erythrocytosis. Am. J. Hematol. 86, 962-964 (2011).
-
(2011)
Am. J. Hematol.
, vol.86
, pp. 962-964
-
-
McMullin, M.F.1
Wu, C.2
Percy, M.J.3
Tong, W.4
-
30
-
-
84922213806
-
Recurrent ETNK1 mutations in atypical chronic myeloid leukemia
-
Gambacorti-Passerini, C.B., et al. Recurrent ETNK1 mutations in atypical chronic myeloid leukemia. Blood 125, 499-503 (2015).
-
(2015)
Blood
, vol.125
, pp. 499-503
-
-
Gambacorti-Passerini, C.B.1
-
31
-
-
68949100415
-
Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutants
-
Yang, Z., et al. Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutants. Mol. Cell. Biol. 29, 4376-4393 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4376-4393
-
-
Yang, Z.1
-
32
-
-
84873530537
-
High frequency of GATA2 mutations in patients with mild chronic neutropenia evolving to MonoMac syndrome, myelodysplasia, and acute myeloid leukemia
-
Pasquet, M., et al. High frequency of GATA2 mutations in patients with mild chronic neutropenia evolving to MonoMac syndrome, myelodysplasia, and acute myeloid leukemia. Blood 121, 822-829 (2013).
-
(2013)
Blood
, vol.121
, pp. 822-829
-
-
Pasquet, M.1
-
33
-
-
84863012056
-
Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature
-
Kazenwadel, J., et al. Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature. Blood 119, 1283-1291 (2012).
-
(2012)
Blood
, vol.119
, pp. 1283-1291
-
-
Kazenwadel, J.1
-
34
-
-
79961074298
-
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
-
Hsu, A.P., et al. Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome. Blood 118, 2653-2655 (2011).
-
(2011)
Blood
, vol.118
, pp. 2653-2655
-
-
Hsu, A.P.1
-
35
-
-
80053383273
-
Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia
-
Hahn, C.N., et al. Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia. Nat. Genet. 43, 1012-1017 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 1012-1017
-
-
Hahn, C.N.1
-
36
-
-
80053385569
-
Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
-
Ostergaard, P., et al. Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome). Nat. Genet. 43, 929-931 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 929-931
-
-
Ostergaard, P.1
-
37
-
-
84899671004
-
Mutations in GATA2 are rare in juvenile myelomonocytic leukemia
-
Stieglitz, E., et al. Mutations in GATA2 are rare in juvenile myelomonocytic leukemia. Blood 123, 1426-1427 (2014).
-
(2014)
Blood
, vol.123
, pp. 1426-1427
-
-
Stieglitz, E.1
-
38
-
-
84873569964
-
GATA2 mutations are frequent in intermediate-risk karyotype AML with biallelic CEBPA mutations and are associated with favorable prognosis
-
Fasan, A., et al. GATA2 mutations are frequent in intermediate-risk karyotype AML with biallelic CEBPA mutations and are associated with favorable prognosis. Leukemia 27, 482-485 (2013).
-
(2013)
Leukemia
, vol.27
, pp. 482-485
-
-
Fasan, A.1
-
39
-
-
84888219405
-
Clinical and biological implications of driver mutations in myelodysplastic syndromes
-
quiz 3699
-
Papaemmanuil, E., et al. Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood 122, 3616-3627, quiz 3699 (2013).
-
(2013)
Blood
, vol.122
, pp. 3616-3627
-
-
Papaemmanuil, E.1
-
40
-
-
84908141853
-
Potential role of RUNX1 in the pathogenesis of juvenile myelomonocytic leukemia (JMML)
-
Bauer, D.E., Loh, M.L., Bhagat, G., Cantor, A.B., & Kung, A.L. Potential role of RUNX1 in the pathogenesis of juvenile myelomonocytic leukemia (JMML). Blood 122, 45 (2013).
-
(2013)
Blood
, vol.122
, pp. 45
-
-
Bauer, D.E.1
Loh, M.L.2
Bhagat, G.3
Cantor, A.B.4
Kung, A.L.5
-
41
-
-
2942667930
-
Point mutations in the RUNX1/AML1 gene: Another actor in RUNX leukemia
-
Osato, M. Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia. Oncogene 23, 4284-4296 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 4284-4296
-
-
Osato, M.1
-
42
-
-
84867030056
-
Wiskott-Aldrich syndrome with unusual clinical features similar to juvenile myelomonocytic leukemia
-
Sano, H., et al. Wiskott-Aldrich syndrome with unusual clinical features similar to juvenile myelomonocytic leukemia. Int. J. Hematol. 96, 279-283 (2012).
-
(2012)
Int. J. Hematol.
, vol.96
, pp. 279-283
-
-
Sano, H.1
-
43
-
-
84875000548
-
Wiskott-Aldrich syndrome presenting with a clinical picture mimicking juvenile myelomonocytic leukaemia
-
Yoshimi, A., et al. Wiskott-Aldrich syndrome presenting with a clinical picture mimicking juvenile myelomonocytic leukaemia. Pediatr. Blood Cancer 60, 836-841 (2013).
-
(2013)
Pediatr. Blood Cancer
, vol.60
, pp. 836-841
-
-
Yoshimi, A.1
-
44
-
-
77951460081
-
X-linked thrombocytopenia (XLT) due to WAS mutations: Clinical characteristics, long-Derm outcome, and treatment options
-
Albert, M.H., et al. X-linked thrombocytopenia (XLT) due to WAS mutations: clinical characteristics, long-Derm outcome, and treatment options. Blood 115, 3231-3238 (2010).
-
(2010)
Blood
, vol.115
, pp. 3231-3238
-
-
Albert, M.H.1
-
45
-
-
78349249756
-
Genetic typing of CBL, ASXL1, RUNX1, TET2 and JAK2 in juvenile myelomonocytic leukaemia reveals a genetic profile distinct from chronic myelomonocytic leukaemia
-
Pérez, B., et al. Genetic typing of CBL, ASXL1, RUNX1, TET2 and JAK2 in juvenile myelomonocytic leukaemia reveals a genetic profile distinct from chronic myelomonocytic leukaemia. Br. J. Haematol. 151, 460-468 (2010).
-
(2010)
Br. J. Haematol.
, vol.151
, pp. 460-468
-
-
Pérez, B.1
-
46
-
-
77953485589
-
Spectrum of molecular defects in juvenile myelomonocytic leukaemia includes ASXL1 mutations
-
Sugimoto, Y., et al. Spectrum of molecular defects in juvenile myelomonocytic leukaemia includes ASXL1 mutations. Br. J. Haematol. 150, 83-87 (2010).
-
(2010)
Br. J. Haematol.
, vol.150
, pp. 83-87
-
-
Sugimoto, Y.1
-
47
-
-
84872085802
-
Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia
-
Kar, S.A., et al. Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia. Haematologica 98, 107-113 (2013).
-
(2013)
Haematologica
, vol.98
, pp. 107-113
-
-
Kar, S.A.1
-
48
-
-
84862502902
-
Mutant DNMT3A: A marker of poor prognosis in acute myeloid leukemia
-
Ribeiro, A.F., et al. Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia. Blood 119, 5824-5831 (2012).
-
(2012)
Blood
, vol.119
, pp. 5824-5831
-
-
Ribeiro, A.F.1
-
49
-
-
78649906060
-
DNMT3A mutations in acute myeloid leukemia
-
Ley, T.J., et al. DNMT3A mutations in acute myeloid leukemia. N. Engl. J. Med. 363, 2424-2433 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 2424-2433
-
-
Ley, T.J.1
-
50
-
-
84923076125
-
Aberrant splicing of U12-Dype introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome
-
Madan, V., et al. Aberrant splicing of U12-Dype introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome. Nat. Commun. 6, 6042 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 6042
-
-
Madan, V.1
-
51
-
-
84858672060
-
Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML
-
Hirabayashi, S., et al. Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML. Blood 119, e96-e99 (2012).
-
(2012)
Blood
, vol.119
, pp. e96-e99
-
-
Hirabayashi, S.1
-
52
-
-
84864885516
-
Novel splicing-factor mutations in juvenile myelomonocytic leukemia
-
Takita, J., et al. Novel splicing-factor mutations in juvenile myelomonocytic leukemia. Leukemia 26, 1879-1881 (2012).
-
(2012)
Leukemia
, vol.26
, pp. 1879-1881
-
-
Takita, J.1
-
53
-
-
80053135096
-
Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A
-
Jankowska, A.M., et al. Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A. Blood 118, 3932-3941 (2011).
-
(2011)
Blood
, vol.118
, pp. 3932-3941
-
-
Jankowska, A.M.1
-
54
-
-
63849095591
-
Intriguing response to azacitidine in a patient with juvenile myelomonocytic leukemia and monosomy 7
-
Furlan, I., et al. Intriguing response to azacitidine in a patient with juvenile myelomonocytic leukemia and monosomy 7. Blood 113, 2867-2868 (2009).
-
(2009)
Blood
, vol.113
, pp. 2867-2868
-
-
Furlan, I.1
-
55
-
-
84898545028
-
The R882H DNMT3A mutation associated with AML dominantly inhibits wild-Dype DNMT3A by blocking its ability to form active tetramers
-
Russler-Germain, D.A., et al. The R882H DNMT3A mutation associated with AML dominantly inhibits wild-Dype DNMT3A by blocking its ability to form active tetramers. Cancer Cell 25, 442-454 (2014).
-
(2014)
Cancer Cell
, vol.25
, pp. 442-454
-
-
Russler-Germain, D.A.1
-
56
-
-
38949143672
-
Development of an allele-specific minimal residual disease assay for patients with juvenile myelomonocytic leukemia
-
Archambeault, S., et al. Development of an allele-specific minimal residual disease assay for patients with juvenile myelomonocytic leukemia. Blood 111, 1124-1127 (2008).
-
(2008)
Blood
, vol.111
, pp. 1124-1127
-
-
Archambeault, S.1
-
57
-
-
84929072644
-
Aggressive congenital juvenile myelomonocytic leukemia associated with somatic KRAS p.G13D mutation and concurrent germline IGF1R duplication
-
Kothari, A., Hulbert, M.L., Cottrell, C.E., & Nguyen, T.T. Aggressive congenital juvenile myelomonocytic leukemia associated with somatic KRAS p.G13D mutation and concurrent germline IGF1R duplication. Leuk. Lymphoma 4 56, 1175-1178 (2015).
-
(2015)
Leuk. Lymphoma
, vol.456
, pp. 1175-1178
-
-
Kothari, A.1
Hulbert, M.L.2
Cottrell, C.E.3
Nguyen, T.T.4
-
58
-
-
84886925691
-
Juvenile myelomonocytic leukemia in a premature neonate mimicking neonatal sepsis
-
doi:10.1016/j.pedneo.2013.06.009 (25 October
-
Lee M.L., et al. Juvenile myelomonocytic leukemia in a premature neonate mimicking neonatal sepsis. Pediatr. Neonatol. doi:10.1016/j.pedneo.2013.06.009 25 October 2013).
-
(2013)
Pediatr. Neonatol.
-
-
Lee, M.L.1
-
59
-
-
84856013431
-
Clonal evolution in cancer
-
Greaves, M., & Maley, C.C. Clonal evolution in cancer. Nature 481, 306-313 (2012).
-
(2012)
Nature
, vol.481
, pp. 306-313
-
-
Greaves, M.1
Maley, C.C.2
-
60
-
-
84873844410
-
Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice
-
Chang, T., et al. Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice. J. Clin. Invest. 123, 335-339 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 335-339
-
-
Chang, T.1
-
61
-
-
79953252390
-
A MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice
-
Lyubynska, N., et al. A MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice. Sci. Transl. Med. 3, 76ra27 (2011).
-
(2011)
Sci. Transl. Med.
, vol.3
, pp. 76ra27
-
-
Lyubynska, N.1
-
62
-
-
58549090093
-
Juvenile myelomonocytic leukemia: A report from the 2nd International JMML Symposium
-
Chan, R.J., Cooper, T., Kratz, C.P., Weiss, B., & Loh, M.L. Juvenile myelomonocytic leukemia: a report from the 2nd International JMML Symposium. Leuk. Res. 33, 355-362 (2009).
-
(2009)
Leuk. Res.
, vol.33
, pp. 355-362
-
-
Chan, R.J.1
Cooper, T.2
Kratz, C.P.3
Weiss, B.4
Loh, M.L.5
-
63
-
-
84923225906
-
Phase II/III trial of a pre-Dransplant farnesyl transferase inhibitor in juvenile myelomonocytic leukemia: A report from the Children's Oncology Group
-
Stieglitz, E., et al. Phase II/III trial of a pre-Dransplant farnesyl transferase inhibitor in juvenile myelomonocytic leukemia: a report from the Children's Oncology Group. Pediatr. Blood Cancer 62, 629-636 (2015).
-
(2015)
Pediatr. Blood Cancer
, vol.62
, pp. 629-636
-
-
Stieglitz, E.1
-
64
-
-
84874025843
-
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
-
Cibulskis, K., et al. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nat. Biotechnol. 31, 213-219 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 213-219
-
-
Cibulskis, K.1
-
65
-
-
79955483667
-
A framework for variation discovery and genotyping using next-generation DNA sequencing data
-
DePristo, M.A., et al. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat. Genet. 43, 491-498 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 491-498
-
-
Depristo, M.A.1
-
66
-
-
77956295988
-
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
-
McKenna, A., et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res. 20, 1297-1303 (2010).
-
(2010)
Genome Res.
, vol.20
, pp. 1297-1303
-
-
McKenna, A.1
-
67
-
-
79951494668
-
Initial genome sequencing and analysis of multiple myeloma
-
Chapman, M.A., et al. Initial genome sequencing and analysis of multiple myeloma. Nature 471, 467-472 (2011).
-
(2011)
Nature
, vol.471
, pp. 467-472
-
-
Chapman, M.A.1
-
68
-
-
34147104969
-
A faster circular binary segmentation algorithm for the analysis of array CGH data
-
Venkatraman, E.S., & Olshen, A.B. A faster circular binary segmentation algorithm for the analysis of array CGH data. Bioinformatics 23, 657-663 (2007).
-
(2007)
Bioinformatics
, vol.23
, pp. 657-663
-
-
Venkatraman, E.S.1
Olshen, A.B.2
-
69
-
-
80053189298
-
Predicting the functional impact of protein mutations: Application to cancer genomics
-
Reva, B., Antipin, Y., & Sander, C. Predicting the functional impact of protein mutations: application to cancer genomics. Nucleic Acids Res. 39, e118 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. e118
-
-
Reva, B.1
Antipin, Y.2
Sander, C.3
-
70
-
-
84946040120
-
COSMIC: Exploring the world's knowledge of somatic mutations in human cancer
-
Forbes, S.A., et al. COSMIC: exploring the world's knowledge of somatic mutations in human cancer. Nucleic Acids Res. 43, D805-D811 (2015).
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. D805-D811
-
-
Forbes, S.A.1
-
71
-
-
84876538609
-
Low-level processing of illumina infinium dna methylation beadarrays
-
Triche, T.J. Jr., Weisenberger, D.J., Van Den Berg, D., Laird, P.W., & Siegmund, K.D. Low-level processing of Illumina Infinium DNA Methylation BeadArrays. Nucleic Acids Res. 41, e90 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. e90
-
-
Triche, T.J.1
Weisenberger, D.J.2
Van Den Berg, D.3
Laird, P.W.4
Siegmund, K.D.5
-
72
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
Cancer Genome Atlas Research Network.
-
Cancer Genome Atlas Research Network. Comprehensive genomic characterization of squamous cell lung cancers. Nature 489, 519-525 (2012).
-
(2012)
Nature
, vol.489
, pp. 519-525
-
-
-
73
-
-
84878593111
-
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity
-
Dulak, A.M., et al. Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nat. Genet. 45, 478-486 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 478-486
-
-
Dulak, A.M.1
-
74
-
-
77952123055
-
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
-
Trapnell, C., et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol. 28, 511-515 (2010).
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 511-515
-
-
Trapnell, C.1
-
75
-
-
84872198346
-
Differential analysis of gene regulation at transcript resolution with RNA-seq
-
Trapnell, C., et al. Differential analysis of gene regulation at transcript resolution with RNA-seq. Nat. Biotechnol. 31, 46-53 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 46-53
-
-
Trapnell, C.1
-
76
-
-
33845382806
-
Nonparametric-estimation from incomplete observations
-
Kaplan, E.L., & Meier, P. Nonparametric-estimation from incomplete observations. J. Am. Stat. Assoc. 53, 457-481 (1958).
-
(1958)
J. Am. Stat. Assoc.
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
77
-
-
0000336139
-
Regression models and life-Dables
-
Cox, D.R. Regression models and life-Dables. J. R. Stat. Soc., B 34, 187-220 (1972).
-
(1972)
J. R. Stat. Soc., B
, vol.34
, pp. 187-220
-
-
Cox, D.R.1
-
78
-
-
0000120995
-
A class of K-sample tests for comparing the cumulative incidence of a competing risk
-
Gray, R.J. A class of K-sample tests for comparing the cumulative incidence of a competing risk. Ann. Stat. 16, 1141-1154 (1988).
-
(1988)
Ann. Stat.
, vol.16
, pp. 1141-1154
-
-
Gray, R.J.1
|