Defeating EpCAM+ liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma

Journal of Hepatology

Volumn 63, Issue 5, 2015, Pages 1164-1172

  Nio, Kouki ^a   Yamashita, Taro ^a   Okada, Hikari ^a   Kondo, Mitsumasa ^a   Hayashi, Takehiro ^a   Hara, Yasumasa ^a   Nomura, Yoshimoto ^a   Zeng, Sha Sha ^a   Yoshida, Mariko ^a   Hayashi, Tomoyuki ^a   Sunagozaka, Hajime ^a   Oishi, Naoki ^a   Honda, Masao ^a   Kaneko, Shuichi ^a  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMODOMAIN HELICASE DNA BINDING PROTEIN 4; EPIRUBICIN; EPITHELIAL CELL ADHESION MOLECULE; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITOR; HISTONE H2AX; KRT19 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; RUCAPARIB; SMALL INTERFERING RNA; SUBEROHYDROXAMIC ACID; TCF4 PROTEIN; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; AUTOANTIGEN; CHD4 PROTEIN, HUMAN; EPCAM PROTEIN, HUMAN; RNA; TUMOR MARKER;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER PROGNOSIS; CANCER STEM CELL; CANCER SURGERY; CANCER SURVIVAL; CELL PROLIFERATION; CHEMOSENSITIVITY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFICACY; DRUG RESISTANCE; EPIGENETICS; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE CONTROL; GENE OVEREXPRESSION; GENE SILENCING; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; LIVER RESECTION; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADICAL RESECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WNT SIGNALING PATHWAY; ANIMAL; BIOSYNTHESIS; EXPERIMENTAL LIVER NEOPLASM; GENE EXPRESSION REGULATION; GENETICS; LIVER; LIVER TUMOR; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; PROGNOSIS; RETROSPECTIVE STUDY; SURGERY; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; AUTOANTIGENS; BIOMARKERS, TUMOR; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; EPITHELIAL CELL ADHESION MOLECULE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATECTOMY; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER; LIVER NEOPLASMS; LIVER NEOPLASMS, EXPERIMENTAL; MI-2 NUCLEOSOME REMODELING AND DEACETYLASE COMPLEX; MICE; MICE, INBRED NOD; NEOPLASTIC STEM CELLS; PROGNOSIS; RETROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM;

EID: 84945439225     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.06.009     Document Type: Article

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