Honey feeding protects kidney against cisplatin nephrotoxicity through suppression of inflammation

Clinical and Experimental Pharmacology and Physiology

Volumn 42, Issue 8, 2015, Pages 843-848

  Hamad, Rania ^a,b   Jayakumar, Calpurnia ^a   Ranganathan, Punithavathi ^a   Mohamed, Riyaz ^a   El Hamamy, Mahmoud M I ^b   Dessouki, Amina A ^b   Ibrahim, Abdelazim ^b   Ramesh, Ganesan ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b Suez Canal University Faculty of Medicine   (Egypt)

Author keywords

Acute kidney injury; Cisplatin; Honey; Inflammation; Nephrotoxicity; NFkB

Indexed keywords

CISPLATIN; CREATININE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ANTINEOPLASTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL INFILTRATION; CREATININE BLOOD LEVEL; ENDOTHELIUM CELL; HONEY; INFLAMMATION; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; ANIMAL; C57BL MOUSE; CELL PROTECTION; DRUG EFFECTS; INJURIES; KIDNEY; METABOLISM; PATHOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; CISPLATIN; CYTOPROTECTION; HONEY; INFLAMMATION; KIDNEY; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B;

EID: 84945270392     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12433     Document Type: Article

References (24)

1. Liangos O, Wald R, O'Bell JW, Price L, Pereira BJ, Jaber BL. Epidemiology and outcomes of acute renal failure in hospitalized patients: A national survey. Clin. J. Am. Soc. Nephrol. 2006; 1: 43-51.
2. Musu M, Finco G, Antonucci R et al. Acute nephrotoxicity of NSAID from the foetus to the adult. Eur. Rev. Med. Pharmacol. Sci. 2011; 15: 1461-72.
3. Allgren RL, Marbury TC, Rahman SN et al. Anaritide in acute tubular necrosis. Auriculin Anaritide Acute Renal Failure Study Group. N. Engl. J. Med. 1997; 336: 828-34.
4. Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N. Engl. J. Med. 1996; 334: 1448-60.
5. Miller RP, Tadagavadi RK, Ramesh G, Reeves WB. Mechanisms of Cisplatin nephrotoxicity. Toxins (Basel) 2010; 2: 2490-518.
6. Wang D, Lippard SJ. Cellular processing of platinum anticancer drugs. Nat. Rev. Drug Discov. 2005; 4: 307-20.
7. Pabla N, Dong Z. Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies. Kidney Int. 2008; 73: 994-1007.
8. Ramesh G, Reeves WB. TNFR2-mediated apoptosis and necrosis in cisplatin-induced acute renal failure. Am. J. Physiol. Renal. Physiol. 2003; 285: F610-18.
9. Zhang B, Ramesh G, Uematsu S, Akira S, Reeves WB. TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity. J. Am. Soc. Nephrol. 2008; 19: 923-32.
10. Ramesh G, Reeves WB. TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity. J. Clin. Invest. 2002; 110: 835-42.
11. Arany I, Safirstein RL. Cisplatin nephrotoxicity. Semin. Nephrol. 2003; 23: 460-4.
12. Baliga R, Ueda N, Walker PD, Shah SV. Oxidant mechanisms in toxic acute renal failure. Drug Metab. Rev. 1999; 31: 971-97.
13. Deng J, Kohda Y, Chiao H et al. Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury. Kidney Int. 2001; 60: 2118-28.
14. Ramesh G, Reeves WB. Salicylate reduces cisplatin nephrotoxicity by inhibition of tumor necrosis factor-alpha. Kidney Int. 2004; 65: 490-9.
15. Ramesh G, Reeves WB. p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice. Am. J. Physiol. Renal. Physiol. 2005; 289: F166-74.
16. White JW. Composition of honey. In: Crane E (ed.). Honey: A Comprehensive Survey. Bee Research Association and Chalfont St Peter, London, UK, 1975; 157-206.
17. El Denshary ES, Al Gahazali MA, Mannaa FA, Salem HA, Hassan NS, Abdel-Wahhab MA. Dietary honey and ginseng protect against carbon tetrachloride-induced hepatonephrotoxicity in rats. Exp. Toxicol. Pathol. 2012; 64: 753-60.
18. Khalil MI, Sulaiman SA, Boukraa L. Antioxidant properties of honey and its role in preventing health disorder. Open Nutraceuticals J. 2015; 3: 6-16.
19. Facino RM. Honey in tumor surgery. Arch. Surg. 2004; 139: 802.
20. Galal RM, Zaki HF, Seif El-Nasr MM, Agha AM. Potential protective effect of honey against paracetamol-induced hepatotoxicity. Arch. Iran. Med. 2012; 15: 674-80.
21. Morgan MJ, Liu Z. Crosstalk of reactive oxygen species and NF-[kappa]B signaling. Cell Res. 2011; 21: 103-15.
22. Wang W, Li C, Summer SN et al. Role of AQP1 in endotoxemia-induced acute kidney injury. Am. J. Physiol. Renal. Physiol. 2008; 294: F1473-80.
23. Ramesh G, Zhang B, Uematsu S, Akira S, Reeves WB. Endotoxin and cisplatin synergistically induce renal dysfunction and cytokine production in mice. Am. J. Physiol. Renal. Physiol. 2007; 293: F325-32.
24. Ranganathan P, Jayakumar C, Navankasattusas S, Li DY, Kim I, Ramesh G. UNC5B receptor deletion exacerbates tissue injury in response to AKI. J. Am. Soc. Nephrol. 2014; 25: 239-49.