메뉴 건너뛰기




Volumn 4, Issue , 2014, Pages

RhoA and membrane fluidity mediates the spatially polarized Src/FAK activation in response to shear stress

Author keywords

[No Author keywords available]

Indexed keywords

4-AMINO-5-(4-METHYLPHENYL)-7-(TERT-BUTYL)PYRAZOLO(3,4-D)PYRIMIDINE; BENZYL ALCOHOL; CYTOCHALASIN D; FOCAL ADHESION KINASE; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; RAS PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84945228883     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep07008     Document Type: Article
Times cited : (39)

References (49)
  • 1
    • 0345687176 scopus 로고    scopus 로고
    • Src kinase activation by direct interaction with the integrin beta cytoplasmic domain
    • Arias-Salgado, E. G. et al. Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. Proc Natl Acad Sci U S A 100, 13298-13302 (2003).
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 13298-13302
    • Arias-Salgado, E.G.1
  • 2
    • 34047245477 scopus 로고    scopus 로고
    • Integrin alpha v beta 3 controls activity and oncogenic potential of primed c-Src
    • Huveneers, S. et al. Integrin alpha v beta 3 controls activity and oncogenic potential of primed c-Src. Cancer Res 67, 2693-2700 (2007).
    • (2007) Cancer Res , vol.67 , pp. 2693-2700
    • Huveneers, S.1
  • 4
    • 17844388845 scopus 로고    scopus 로고
    • Visualizing the mechanical activation of Src
    • Wang, Y. et al. Visualizing the mechanical activation of Src. Nature 434, 1040-1045 (2005).
    • (2005) Nature , vol.434 , pp. 1040-1045
    • Wang, Y.1
  • 5
    • 0033175564 scopus 로고    scopus 로고
    • Selective regulation of integrin - Cytoskeleton interactions by the tyrosine kinase Src
    • Felsenfeld, D. P., Schwartzberg, P. L., Venegas, A., Tse, R. & Sheetz, M. P. Selective regulation of integrin - cytoskeleton interactions by the tyrosine kinase Src. Nat Cell Biol 1, 200-206 (1999).
    • (1999) Nat Cell Biol , vol.1 , pp. 200-206
    • Felsenfeld, D.P.1    Schwartzberg, P.L.2    Venegas, A.3    Tse, R.4    Sheetz, M.P.5
  • 6
    • 33748286819 scopus 로고    scopus 로고
    • Integrin-regulated FAK-Src signaling in normal and cancer cells
    • Mitra, S. K. & Schlaepfer, D. D. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol 18, 516-523 (2006).
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 516-523
    • Mitra, S.K.1    Schlaepfer, D.D.2
  • 7
    • 3042717667 scopus 로고    scopus 로고
    • Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold
    • Chodniewicz, D. & Klemke, R. L. Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold. Biochim Biophys Acta 1692, 63-76 (2004).
    • (2004) Biochim Biophys Acta , vol.1692 , pp. 63-76
    • Chodniewicz, D.1    Klemke, R.L.2
  • 8
    • 66849101632 scopus 로고    scopus 로고
    • Adhesion signaling-crosstalk between integrins, Src and Rho
    • Huveneers, S.&Danen, E. H. Adhesion signaling-crosstalk between integrins, Src and Rho. J Cell Sci 122, 1059-1069 (2009).
    • (2009) J Cell Sci , vol.122 , pp. 1059-1069
    • Huveneers, S.1    Danen, E.H.2
  • 9
    • 9144257875 scopus 로고    scopus 로고
    • Shear stress increases ICAM-1 and decreases VCAM-1 and Eselectin expressions induced by tumor necrosis factor-[alpha] in endothelial cells
    • Chiu, J. J. et al. Shear stress increases ICAM-1 and decreases VCAM-1 and Eselectin expressions induced by tumor necrosis factor-[alpha] in endothelial cells. Arterioscler Thromb Vasc Biol 24, 73-79 (2004).
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 73-79
    • Chiu, J.J.1
  • 10
    • 38349117219 scopus 로고    scopus 로고
    • Laminar shear stress up-regulates peroxiredoxins (PRX) in endothelial cells: PRX 1 as a mechanosensitive antioxidant
    • Mowbray, A. L., Kang, D. H., Rhee, S. G., Kang, S. W.& Jo, H. Laminar shear stress up-regulates peroxiredoxins (PRX) in endothelial cells: PRX 1 as a mechanosensitive antioxidant. J Biol Chem 283, 1622-1627 (2008).
    • (2008) J Biol Chem , vol.283 , pp. 1622-1627
    • Mowbray, A.L.1    Kang, D.H.2    Rhee, S.G.3    Kang, S.W.4    Jo, H.5
  • 11
    • 34247894035 scopus 로고    scopus 로고
    • Laminar shear stress up-regulates the expression of stearoyl-CoA desaturase-1 in vascular endothelial cells
    • Qin, X. et al. Laminar shear stress up-regulates the expression of stearoyl-CoA desaturase-1 in vascular endothelial cells. Cardiovasc Res 74, 506-514 (2007).
    • (2007) Cardiovasc Res , vol.74 , pp. 506-514
    • Qin, X.1
  • 12
    • 0031838055 scopus 로고    scopus 로고
    • Shear stress activates p60src-Ras-MAPK signaling pathways in vascular endothelial cells
    • Jalali, S. et al. Shear stress activates p60src-Ras-MAPK signaling pathways in vascular endothelial cells. Arterioscler Thromb Vasc Biol 18, 227-234 (1998).
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 227-234
    • Jalali, S.1
  • 13
    • 0030729489 scopus 로고    scopus 로고
    • Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases
    • Li, S. et al. Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases. J Biol Chem 272, 30455-30462 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 30455-30462
    • Li, S.1
  • 14
    • 0031696486 scopus 로고    scopus 로고
    • SRC binding to the cytoskeleton, triggered by growth cone attachment to laminin, is protein tyrosine phosphatase-dependent
    • Helmke, S., Lohse, K.,Mikule, K.,Wood,M. R.&Pfenninger, K. H. SRC binding to the cytoskeleton, triggered by growth cone attachment to laminin, is protein tyrosine phosphatase-dependent. J Cell Sci 111 (Pt 16), 2465-2475 (1998).
    • (1998) J Cell Sci , vol.111 , pp. 2465-2475
    • Helmke, S.1    Lohse, K.2    Mikule, K.3    Wood, M.R.4    Pfenninger, K.H.5
  • 15
    • 12344250442 scopus 로고    scopus 로고
    • Integrin mechanotransduction stimulates caveolin-1 phosphorylation and recruitment of Csk to mediate actin reorganization
    • Radel, C. & Rizzo, V. Integrin mechanotransduction stimulates caveolin-1 phosphorylation and recruitment of Csk to mediate actin reorganization. Am J Physiol Heart Circ Physiol 288, H936-945 (2005).
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. H936-945
    • Radel, C.1    Rizzo, V.2
  • 16
    • 25144510997 scopus 로고    scopus 로고
    • A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
    • Tzima, E. et al. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 437, 426-431 (2005).
    • (2005) Nature , vol.437 , pp. 426-431
    • Tzima, E.1
  • 17
    • 0034809533 scopus 로고    scopus 로고
    • Effects of flow patterns on endothelial cell migration into a zone of mechanical denudation
    • Hsu, P. P. et al. Effects of flow patterns on endothelial cell migration into a zone of mechanical denudation. Biochem Biophys Res Commun 285, 751-759 (2001).
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 751-759
    • Hsu, P.P.1
  • 18
    • 0032391939 scopus 로고    scopus 로고
    • Fluid shear stress modulation of gene expression in endothelial cells
    • Braddock, M. et al. Fluid Shear Stress Modulation of Gene Expression in Endothelial Cells. News Physiol Sci 13, 241-246 (1998).
    • (1998) News Physiol Sci , vol.13 , pp. 241-246
    • Braddock, M.1
  • 19
    • 27944431593 scopus 로고    scopus 로고
    • Mechanotransduction in endothelial cell migration
    • Li, S., Huang, N. F. & Hsu, S. Mechanotransduction in endothelial cell migration. J Cell Biochem 96, 1110-1126 (2005).
    • (2005) J Cell Biochem , vol.96 , pp. 1110-1126
    • Li, S.1    Huang, N.F.2    Hsu, S.3
  • 20
    • 0037121966 scopus 로고    scopus 로고
    • Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression
    • Tzima, E. et al.Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. Embo J 21, 6791-6800 (2002).
    • (2002) Embo J , vol.21 , pp. 6791-6800
    • Tzima, E.1
  • 21
    • 0042232206 scopus 로고    scopus 로고
    • Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress
    • Tzima, E., Kiosses, W. B., del Pozo, M. A. & Schwartz, M. A. Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress. J Biol Chem 278, 31020-31023 (2003).
    • (2003) J Biol Chem , vol.278 , pp. 31020-31023
    • Tzima, E.1    Kiosses, W.B.2    Del Pozo, M.A.3    Schwartz, M.A.4
  • 22
    • 0036385662 scopus 로고    scopus 로고
    • Arterial enlargement in response to high flow requires early expression of matrix metalloproteinases to degrade extracellular matrix
    • Sho, E. et al. Arterial enlargement in response to high flow requires early expression of matrix metalloproteinases to degrade extracellular matrix. Exp Mol Pathol 73, 142-153 (2002).
    • (2002) Exp Mol Pathol , vol.73 , pp. 142-153
    • Sho, E.1
  • 23
    • 0027736281 scopus 로고
    • Influence of shear stress on endothelial cell shapes and junction complexes at flow dividers of aortic bifurcations in cholesterol-fed rabbits
    • Okano, M. & Yoshida, Y. Influence of shear stress on endothelial cell shapes and junction complexes at flow dividers of aortic bifurcations in cholesterol-fed rabbits. Front Med Biol Eng 5, 95-120 (1993).
    • (1993) Front Med Biol Eng , vol.5 , pp. 95-120
    • Okano, M.1    Yoshida, Y.2
  • 24
    • 52449093918 scopus 로고    scopus 로고
    • Nitric oxide-dependent stimulation of endothelial cell proliferation by sustained high flow
    • Metaxa, E. et al. Nitric oxide-dependent stimulation of endothelial cell proliferation by sustained high flow. Am J Physiol Heart Circ Physiol 295, H736-742 (2008).
    • (2008) Am J Physiol Heart Circ Physiol , vol.295 , pp. H736-742
    • Metaxa, E.1
  • 25
    • 34249823676 scopus 로고    scopus 로고
    • Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation
    • Meng, H. et al. Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation. Stroke 38, 1924-1931 (2007).
    • (2007) Stroke , vol.38 , pp. 1924-1931
    • Meng, H.1
  • 26
    • 33845204417 scopus 로고    scopus 로고
    • A model system for mapping vascular responses to complex hemodynamics at arterial bifurcations in vivo
    • discussion 1100-1091
    • Meng, H. et al. A model system for mapping vascular responses to complex hemodynamics at arterial bifurcations in vivo. Neurosurgery 59, 1094-1100; discussion 1100-1091 (2006).
    • (2006) Neurosurgery , vol.59 , pp. 1094-1100
    • Meng, H.1
  • 27
    • 79958843368 scopus 로고    scopus 로고
    • Two distinct phases of calcium signalling under flow
    • Liu, B., Lu, S., Zheng, S., Jiang, Z. & Wang, Y. Two distinct phases of calcium signalling under flow. Cardiovasc Res 91, 124-133 (2011).
    • (2011) Cardiovasc Res , vol.91 , pp. 124-133
    • Liu, B.1    Lu, S.2    Zheng, S.3    Jiang, Z.4    Wang, Y.5
  • 28
    • 44349189707 scopus 로고    scopus 로고
    • Rapid signal transduction in living cells is a unique feature of mechanotransduction
    • Na, S. et al. Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proc Natl Acad Sci U S A 105, 6626-6631 (2008).
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 6626-6631
    • Na, S.1
  • 29
    • 55749093427 scopus 로고    scopus 로고
    • Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors
    • Ouyang, M., Sun, J., Chien, S. & Wang, Y. Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors. Proc Natl Acad Sci U S A 105, 14353-14358 (2008).
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14353-14358
    • Ouyang, M.1    Sun, J.2    Chien, S.3    Wang, Y.4
  • 30
    • 0036482874 scopus 로고    scopus 로고
    • Rate sensitivity of shearinduced changes in the lateral diffusion of endothelial cell membrane lipids: A role for membrane perturbation in shear-induced MAPK activation
    • Butler, P. J., Tsou, T. C., Li, J. Y., Usami, S. & Chien, S. Rate sensitivity of shearinduced changes in the lateral diffusion of endothelial cell membrane lipids: a role for membrane perturbation in shear-induced MAPK activation. FASEB J 16, 216-218 (2002).
    • (2002) FASEB J , vol.16 , pp. 216-218
    • Butler, P.J.1    Tsou, T.C.2    Li, J.Y.3    Usami, S.4    Chien, S.5
  • 31
    • 0034996180 scopus 로고    scopus 로고
    • Shear stress induces a timeand position-dependent increase in endothelial cell membrane fluidity
    • Butler, P. J., Norwich, G., Weinbaum, S. & Chien, S. Shear stress induces a timeand position-dependent increase in endothelial cell membrane fluidity. Am J Physiol Cell Physiol 280, C962-969 (2001).
    • (2001) Am J Physiol Cell Physiol , vol.280 , pp. C962-969
    • Butler, P.J.1    Norwich, G.2    Weinbaum, S.3    Chien, S.4
  • 32
    • 48249112624 scopus 로고    scopus 로고
    • The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging
    • Lu, S. et al. The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging. PLoS Comput Biol 4, e1000127 (2008).
    • (2008) PLoS Comput Biol , vol.4
    • Lu, S.1
  • 33
    • 0031850240 scopus 로고    scopus 로고
    • The cytoskeleton and cell signaling: Component localization and mechanical coupling
    • Janmey, P. A. The cytoskeleton and cell signaling: component localization and mechanical coupling. Physiol Rev 78, 763-781 (1998).
    • (1998) Physiol Rev , vol.78 , pp. 763-781
    • Janmey, P.A.1
  • 34
    • 65649102678 scopus 로고    scopus 로고
    • Short-term shear stress induces rapid actin dynamics in living endothelial cells
    • Choi, C. K. & Helmke, B. P. Short-Term Shear Stress Induces Rapid Actin Dynamics in Living Endothelial Cells. Mol Cell Biomech 5, 247-258 (2008).
    • (2008) Mol Cell Biomech , vol.5 , pp. 247-258
    • Choi, C.K.1    Helmke, B.P.2
  • 35
    • 58049213790 scopus 로고    scopus 로고
    • Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology
    • Davies, P. F. Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat Clin Pract Cardiovasc Med 6, 16-26 (2009).
    • (2009) Nat Clin Pract Cardiovasc Med , vol.6 , pp. 16-26
    • Davies, P.F.1
  • 36
    • 33644850341 scopus 로고    scopus 로고
    • Endothelial actin cytoskeleton remodeling during mechanostimulation with fluid shear stress
    • Osborn, E. A., Rabodzey, A., Dewey, C. F., Jr. & Hartwig, J. H. Endothelial actin cytoskeleton remodeling during mechanostimulation with fluid shear stress. Am J Physiol Cell Physiol 290, C444-452 (2006).
    • (2006) Am J Physiol Cell Physiol , vol.290 , pp. C444-452
    • Osborn, E.A.1    Rabodzey, A.2    Dewey, C.F.3    Hartwig, J.H.4
  • 37
    • 0030482560 scopus 로고    scopus 로고
    • Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins
    • Fincham,V. J. et al. Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins. J Cell Biol 135, 1551-1564 (1996).
    • (1996) J Cell Biol , vol.135 , pp. 1551-1564
    • Fincham, V.J.1
  • 38
    • 10644219505 scopus 로고    scopus 로고
    • RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane
    • Sandilands, E. et al. RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane. Dev Cell 7, 855-869 (2004).
    • (2004) Dev Cell , vol.7 , pp. 855-869
    • Sandilands, E.1
  • 39
    • 0037731922 scopus 로고    scopus 로고
    • Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases
    • Wojciak-Stothard, B. & Ridley, A. J. Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases. J Cell Biol 161, 429-439 (2003).
    • (2003) J Cell Biol , vol.161 , pp. 429-439
    • Wojciak-Stothard, B.1    Ridley, A.J.2
  • 40
    • 0842325725 scopus 로고    scopus 로고
    • Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways
    • Jaffe, A. B., Aspenstrom, P. & Hall, A. Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways. Mol Cell Biol 24, 1736-1746 (2004).
    • (2004) Mol Cell Biol , vol.24 , pp. 1736-1746
    • Jaffe, A.B.1    Aspenstrom, P.2    Hall, A.3
  • 41
    • 77956064817 scopus 로고    scopus 로고
    • Cell adhesion: Integrating cytoskeletal dynamics and cellular tension
    • Parsons, J. T., Horwitz, A. R. & Schwartz, M. A. Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nat Rev Mol Cell Biol 11, 633-643 (2010).
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 633-643
    • Parsons, J.T.1    Horwitz, A.R.2    Schwartz, M.A.3
  • 42
    • 0035954424 scopus 로고    scopus 로고
    • Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells
    • Laukaitis, C. M.,Webb, D. J., Donais, K. &Horwitz, A. F. Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells. J Cell Biol 153, 1427-1440 (2001).
    • (2001) J Cell Biol , vol.153 , pp. 1427-1440
    • Laukaitis, C.M.1    Webb, D.J.2    Donais, K.3    Horwitz, A.F.4
  • 43
    • 0033560932 scopus 로고    scopus 로고
    • Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress
    • Li, S. et al. Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress. J Clin Invest 103, 1141-1150 (1999).
    • (1999) J Clin Invest , vol.103 , pp. 1141-1150
    • Li, S.1
  • 44
    • 0035801529 scopus 로고    scopus 로고
    • Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment
    • Tzima, E., del Pozo, M. A., Shattil, S. J., Chien, S. & Schwartz, M. A. Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment. Embo J 20, 4639-4647 (2001).
    • (2001) Embo J , vol.20 , pp. 4639-4647
    • Tzima, E.1    Del Pozo, M.A.2    Shattil, S.J.3    Chien, S.4    Schwartz, M.A.5
  • 45
    • 7244229657 scopus 로고    scopus 로고
    • Hyperosmotic stress induces rapid focal adhesion kinase phosphorylation at tyrosines 397 and 577. Role of Src family kinases and Rho family GTPases
    • Lunn, J. A. & Rozengurt, E. Hyperosmotic stress induces rapid focal adhesion kinase phosphorylation at tyrosines 397 and 577. Role of Src family kinases and Rho family GTPases. J Biol Chem 279, 45266-45278 (2004).
    • (2004) J Biol Chem , vol.279 , pp. 45266-45278
    • Lunn, J.A.1    Rozengurt, E.2
  • 46
    • 77957272673 scopus 로고    scopus 로고
    • Rho and Ras GTPases in axon growth, guidance, and branching
    • Hall, A. & Lalli, G. Rho and Ras GTPases in axon growth, guidance, and branching. Cold Spring Harb Perspect Biol 2, a001818 (2010).
    • (2010) Cold Spring Harb Perspect Biol , vol.2 , pp. a001818
    • Hall, A.1    Lalli, G.2
  • 48
    • 26244434925 scopus 로고    scopus 로고
    • Polarized downregulation of the paxillinp130CAS-Rac1 pathway induced by shear flow
    • Zaidel-Bar, R., Kam, Z. & Geiger, B. Polarized downregulation of the paxillinp130CAS-Rac1 pathway induced by shear flow. J Cell Sci 118, 3997-4007 (2005).
    • (2005) J Cell Sci , vol.118 , pp. 3997-4007
    • Zaidel-Bar, R.1    Kam, Z.2    Geiger, B.3
  • 49
    • 70849098229 scopus 로고    scopus 로고
    • Rapid activation of Rac GTPase in living cells by force is independent of Src
    • Poh, Y. C. et al. Rapid activation of Rac GTPase in living cells by force is independent of Src. PLoS One 4, e7886 (2009).
    • (2009) PLoS One , vol.4
    • Poh, Y.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.