메뉴 건너뛰기




Volumn 6, Issue 30, 2015, Pages 29753-29770

The expression pattern of PFKFB3 enzyme distinguishes between induced-pluripotent stem cells and cancer stem cells

Author keywords

Cancer stem cells; Induced pluripotent stem cells; PFK1; PFKFB3; R point

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; 6 PHOSPHOFRUCTOKINASE; ALDEHYDE DEHYDROGENASE; PFKFB3 PROTEIN, HUMAN;

EID: 84945137303     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4995     Document Type: Article
Times cited : (42)

References (57)
  • 1
    • 84878281982 scopus 로고    scopus 로고
    • Induced pluripotent stem cells in medicine and biology
    • Takahashi K, Yamanaka S. Induced pluripotent stem cells in medicine and biology. Development. 2013; 140:2457-2461.
    • (2013) Development , vol.140 , pp. 2457-2461
    • Takahashi, K.1    Yamanaka, S.2
  • 5
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, Weinberg RA. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet. 2008; 40:499-507.
    • (2008) Nat Genet , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 8
    • 84869028375 scopus 로고    scopus 로고
    • Selfrenewal and pluripotency acquired through somatic reprogramming to human cancer stem cells
    • Nagata S, Hirano K, Kanemori M, Sun LT, Tada T. Selfrenewal and pluripotency acquired through somatic reprogramming to human cancer stem cells. PloS one. 2012; 7:e48699.
    • (2012) PloS one , vol.7
    • Nagata, S.1    Hirano, K.2    Kanemori, M.3    Sun, L.T.4    Tada, T.5
  • 9
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: an old idea-a paradigm shift
    • discussion 1895-1886
    • Wicha MS, Liu S, Dontu G. Cancer stem cells: an old idea-a paradigm shift. Cancer Res. 2006; 66:1883-1890. discussion 1895-1886.
    • (2006) Cancer Res , vol.66 , pp. 1883-1890
    • Wicha, M.S.1    Liu, S.2    Dontu, G.3
  • 12
    • 66149179125 scopus 로고    scopus 로고
    • Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine
    • Knoepfler PS. Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. Stem cells. 2009; 27:1050-1056.
    • (2009) Stem cells , vol.27 , pp. 1050-1056
    • Knoepfler, P.S.1
  • 15
    • 77951571268 scopus 로고    scopus 로고
    • Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance
    • Harper LJ, Costea DE, Gammon L, Fazil B, Biddle A, Mackenzie IC. Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance. BMC cancer. 2010; 10:166.
    • (2010) BMC cancer , vol.10 , pp. 166
    • Harper, L.J.1    Costea, D.E.2    Gammon, L.3    Fazil, B.4    Biddle, A.5    Mackenzie, I.C.6
  • 16
    • 0028579733 scopus 로고
    • Oncogenes and the strategy of growth factors
    • Baserga R. Oncogenes and the strategy of growth factors. Cell. 1994; 79:927-930.
    • (1994) Cell , vol.79 , pp. 927-930
    • Baserga, R.1
  • 18
    • 0036491845 scopus 로고    scopus 로고
    • The restriction point of the cell cycle
    • Blagosklonny MV, Pardee AB. The restriction point of the cell cycle. Cell cycle. 2002; 1:103-110.
    • (2002) Cell cycle , vol.1 , pp. 103-110
    • Blagosklonny, M.V.1    Pardee, A.B.2
  • 20
    • 79955076736 scopus 로고    scopus 로고
    • Two ubiquitin ligases, APC/CCdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle
    • Tudzarova S, Colombo SL, Stoeber K, Carcamo S, Williams GH, Moncada S. Two ubiquitin ligases, APC/CCdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle. Proc Natl Acad Sci U S A. 2011; 108:5278-5283.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 5278-5283
    • Tudzarova, S.1    Colombo, S.L.2    Stoeber, K.3    Carcamo, S.4    Williams, G.H.5    Moncada, S.6
  • 21
    • 84890159876 scopus 로고    scopus 로고
    • Cancer cell metabolism: implications for therapeutic targets
    • Jang M, Kim SS, Lee J. Cancer cell metabolism: implications for therapeutic targets. Exp Mol Med. 2013; 45:e45.
    • (2013) Exp Mol Med , vol.45
    • Jang, M.1    Kim, S.S.2    Lee, J.3
  • 24
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science. 1956; 123:309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 26
    • 67349131613 scopus 로고    scopus 로고
    • Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatases in cancer
    • Yalcin A, Telang S, Clem B, Chesney J. Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatases in cancer. Experimental and molecular pathology. 2009; 86:174-179.
    • (2009) Experimental and molecular pathology , vol.86 , pp. 174-179
    • Yalcin, A.1    Telang, S.2    Clem, B.3    Chesney, J.4
  • 27
    • 38049077430 scopus 로고    scopus 로고
    • 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is up-regulated in high-grade astrocytomas
    • Kessler R, Bleichert F, Warnke JP, Eschrich K. 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is up-regulated in high-grade astrocytomas. Journal of neuro-oncology. 2008; 86:257-264.
    • (2008) Journal of neuro-oncology , vol.86 , pp. 257-264
    • Kessler, R.1    Bleichert, F.2    Warnke, J.P.3    Eschrich, K.4
  • 29
    • 33746037631 scopus 로고    scopus 로고
    • PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells
    • Calvo MN, Bartrons R, Castano E, Perales JC, Navarro-Sabate A, Manzano A. PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells. FEBS letters. 2006; 580:3308-3314.
    • (2006) FEBS letters , vol.580 , pp. 3308-3314
    • Calvo, M.N.1    Bartrons, R.2    Castano, E.3    Perales, J.C.4    Navarro-Sabate, A.5    Manzano, A.6
  • 31
    • 0024473604 scopus 로고
    • G1 events and regulation of cell proliferation
    • Pardee AB. G1 events and regulation of cell proliferation. Science. 1989; 246:603-608.
    • (1989) Science , vol.246 , pp. 603-608
    • Pardee, A.B.1
  • 34
    • 84878893949 scopus 로고    scopus 로고
    • Profiling of normal and malignant breast tissue show CD44 high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers
    • Ghebeh H, Sleiman GM, Manogaran PS, Al-Mazrou A, Barhoush E, Al-Mohanna FH, Tulbah A, Al-Faqeeh K, Adra CN. Profiling of normal and malignant breast tissue show CD44 high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers. BMC cancer. 2013; 13:289.
    • (2013) BMC cancer , vol.13 , pp. 289
    • Ghebeh, H.1    Sleiman, G.M.2    Manogaran, P.S.3    Al-Mazrou, A.4    Barhoush, E.5    Al-Mohanna, F.H.6    Tulbah, A.7    Al-Faqeeh, K.8    Adra, C.N.9
  • 36
    • 48949119473 scopus 로고    scopus 로고
    • Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
    • Fillmore CM, Kuperwasser C. Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast cancer research: BCR. 2008; 10:R25.
    • (2008) Breast cancer research: BCR , vol.10
    • Fillmore, C.M.1    Kuperwasser, C.2
  • 38
    • 4944228318 scopus 로고    scopus 로고
    • Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation
    • Minchenko O, Opentanova I, Minchenko D, Ogura T, Esumi H. Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation. FEBS letters. 2004; 576:14-20.
    • (2004) FEBS letters , vol.576 , pp. 14-20
    • Minchenko, O.1    Opentanova, I.2    Minchenko, D.3    Ogura, T.4    Esumi, H.5
  • 41
    • 0037108709 scopus 로고    scopus 로고
    • High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2, PFKFB3) in human cancers
    • Atsumi T, Chesney J, Metz C, Leng L, Donnelly S, Makita Z, Mitchell R, Bucala R. High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2, PFKFB3) in human cancers. Cancer Res. 2002; 62:5881-5887.
    • (2002) Cancer Res , vol.62 , pp. 5881-5887
    • Atsumi, T.1    Chesney, J.2    Metz, C.3    Leng, L.4    Donnelly, S.5    Makita, Z.6    Mitchell, R.7    Bucala, R.8
  • 43
    • 76249114497 scopus 로고    scopus 로고
    • E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation
    • Almeida A, Bolanos JP, Moncada S. E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation. Proc Natl Acad Sci U S A. 2010; 107:738-741.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 738-741
    • Almeida, A.1    Bolanos, J.P.2    Moncada, S.3
  • 44
    • 73949143162 scopus 로고    scopus 로고
    • Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming
    • Becker KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming. Journal of cellular physiology. 2010; 222:103-110.
    • (2010) Journal of cellular physiology , vol.222 , pp. 103-110
    • Becker, K.A.1    Stein, J.L.2    Lian, J.B.3    van Wijnen, A.J.4    Stein, G.S.5
  • 45
    • 84880335966 scopus 로고    scopus 로고
    • Understanding breast cancer stem cell heterogeneity: time to move on to a new research paradigm
    • Mannello F. Understanding breast cancer stem cell heterogeneity: time to move on to a new research paradigm. BMC Med. 2013; 11:169.
    • (2013) BMC Med , vol.11 , pp. 169
    • Mannello, F.1
  • 47
    • 84867425035 scopus 로고    scopus 로고
    • Control of glycolysis through regulation of PFK1: old friends and recent additions
    • Mor I, Cheung EC, Vousden KH. Control of glycolysis through regulation of PFK1: old friends and recent additions. Cold Spring Harb Symp Quant Biol. 2011; 76:211-216.
    • (2011) Cold Spring Harb Symp Quant Biol , vol.76 , pp. 211-216
    • Mor, I.1    Cheung, E.C.2    Vousden, K.H.3
  • 49
    • 0037189542 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
    • Lu H, Forbes RA, Verma A. Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis. J Biol Chem. 2002; 277:23111-23115.
    • (2002) J Biol Chem , vol.277 , pp. 23111-23115
    • Lu, H.1    Forbes, R.A.2    Verma, A.3
  • 50
    • 33846131233 scopus 로고    scopus 로고
    • Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers
    • Bobarykina AY, Minchenko DO, Opentanova IL, Moenner M, Caro J, Esumi H, Minchenko OH. Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers. Acta Biochim Pol. 2006; 53:789-799.
    • (2006) Acta Biochim Pol , vol.53 , pp. 789-799
    • Bobarykina, A.Y.1    Minchenko, D.O.2    Opentanova, I.L.3    Moenner, M.4    Caro, J.5    Esumi, H.6    Minchenko, O.H.7
  • 51
  • 53
    • 70350225829 scopus 로고    scopus 로고
    • The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
    • Heddleston JM, Li Z, McLendon RE, Hjelmeland AB, Rich JN. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell cycle. 2009; 8:3274-3284.
    • (2009) Cell cycle , vol.8 , pp. 3274-3284
    • Heddleston, J.M.1    Li, Z.2    McLendon, R.E.3    Hjelmeland, A.B.4    Rich, J.N.5
  • 55
    • 0028886527 scopus 로고
    • Accumulation of human promyelocytic leukemic (HL-60) cells at two energetic cell cycle checkpoints
    • Sweet S, Singh G. Accumulation of human promyelocytic leukemic (HL-60) cells at two energetic cell cycle checkpoints. Cancer Res. 1995; 55:5164-5167.
    • (1995) Cancer Res , vol.55 , pp. 5164-5167
    • Sweet, S.1    Singh, G.2
  • 57
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001; 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.