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Volumn 442, Issue 2, 2012, Pages 345-356

Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells

Author keywords

6 bisphosphatase (PFKFB3); 6 phosphofructo 2 kinase fructose 2; Breast cancer; Gene regulation; Glycolysis; Metabolism; Progestins

Indexed keywords

16ALPHA ETHYL 21 HYDROXY 19 NORPREGN 4 ENE 3,20 DIONE; 6 PHOSPHOFRUCTO 2 KINASE; FRUCTOSE 2,6 BISPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE; NORGESTREL; PROGESTERONE RECEPTOR; S6 KINASE;

EID: 84856877500     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111418     Document Type: Article
Times cited : (46)

References (51)
  • 1
    • 0036357693 scopus 로고    scopus 로고
    • Role of steroid receptor coactivators and corepressors of progesterone receptors in breast cancer
    • DOI 10.1186/bcr449
    • Gao, X. and Nawaz, Z. (2002) Progesterone receptors - animal models and cell signaling in breast cancer: role of steroid receptor coactivators and corepressors of progesterone receptors in breast cancer. Breast Cancer Res. 4, 182-186 (Pubitemid 34918995)
    • (2002) Breast Cancer Research , vol.4 , Issue.5 , pp. 182-186
    • Gao, X.1    Nawaz, Z.2
  • 2
    • 33947401482 scopus 로고    scopus 로고
    • Integration of rapid signaling events with steroid hormone receptor action in breast and prostate cancer
    • DOI 10.1146/annurev.physiol.69.031905.160319
    • Lange, C. A., Gioeli, D., Hammes, S. R. and Marker, P. C. (2007) Integration of rapid signaling events with steroid hormone receptor action in breast and prostate cancer. Annu. Rev. Physiol. 69, 171-199 (Pubitemid 46457640)
    • (2007) Annual Review of Physiology , vol.69 , pp. 171-199
    • Lange, C.A.1    Gioeli, D.2    Hammes, S.R.3    Marker, P.C.4
  • 3
    • 33750448996 scopus 로고    scopus 로고
    • Induction of Progesterone Target Genes Requires Activation of Erk and Msk Kinases and Phosphorylation of Histone H3
    • DOI 10.1016/j.molcel.2006.10.011, PII S1097276506007003
    • Vicent, G. P., Ballaré, C., Nacht, A. S., Clausell, J., Subtil-Rodríguez, A., Quiles, I., Jordan, A. and Beato, M. (2006) Induction of progesterone target genes requires activation of Erk and Msk kinases and phosphorylation of histone H3. Mol. Cell 24, 367-381 (Pubitemid 44649285)
    • (2006) Molecular Cell , vol.24 , Issue.3 , pp. 367-381
    • Vicent, G.P.1    Ballare, C.2    Nacht, A.S.3    Clausell, J.4    Subtil-Rodriguez, A.5    Quiles, I.6    Jordan, A.7    Beato, M.8
  • 4
    • 67349168694 scopus 로고    scopus 로고
    • Signaling inputs to progesterone receptor gene regulation and promoter selectivity
    • Daniel, A. R., Knutson, T. P. and Lange, C. A. (2009) Signaling inputs to progesterone receptor gene regulation and promoter selectivity. Mol. Cell. Endocrinol. 308, 47-52
    • (2009) Mol. Cell. Endocrinol. , vol.308 , pp. 47-52
    • Daniel, A.R.1    Knutson, T.P.2    Lange, C.A.3
  • 5
    • 0032562712 scopus 로고    scopus 로고
    • Progesterone regulates transcription of the p21(WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300
    • DOI 10.1074/jbc.273.17.10696
    • Owen, G. I., Richer, J. K., Tung, L., Takimoto, G. and Horwitz, K. B. (1998) Progesterone regulates transcription of the p21 (WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300. J. Biol. Chem. 273, 10696-10701 (Pubitemid 28227684)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.17 , pp. 10696-10701
    • Owen, G.I.1    Richer, J.K.2    Tung, L.3    Takimoto, G.4    Horwitz, K.B.5
  • 7
    • 0037085303 scopus 로고    scopus 로고
    • Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells
    • DOI 10.1074/jbc.M110090200
    • Richer, J. K., Jacobsen, B. M., Manning, N. G., Abel, M. G., Wolf, D. M. and Horwitz, K. B. (2002) Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells. J. Biol. Chem. 277, 5209-5218 (Pubitemid 34968565)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.7 , pp. 5209-5218
    • Richer, J.K.1    Jacobsen, B.M.2    Manning, N.G.3    Abel, M.G.4    Wolf, D.M.5    Horwitz, K.B.6
  • 8
    • 0242351198 scopus 로고    scopus 로고
    • Progesterone Receptor (hPR) Upregulates the Fibronectin Promoter Activity in Human Decidual Fibroblasts
    • DOI 10.1089/104454903770238102
    • Tseng, L., Tang, M., Wang, Z. and Mazella, J. (2003) Progesterone receptor (hPR) upregulates the fibronectin promoter activity in human decidual fibroblasts. DNA Cell Biol. 22, 633-640 (Pubitemid 37357733)
    • (2003) DNA and Cell Biology , vol.22 , Issue.10 , pp. 633-640
    • Tseng, L.1    Tang, M.2    Wang, Z.3    Mazella, J.4
  • 9
    • 0032036584 scopus 로고    scopus 로고
    • Activation of the Src/p21(ras)/Erk pathway by progesterone receptor via cross-talk with estrogen receptor
    • DOI 10.1093/emboj/17.7.2008
    • Migliaccio, A., Piccolo, D., Castoria, G., Di Domenico, M., Bilancio, A., Lombardi, M., Gong, W., Beato, M. and Auricchio, F. (1998) Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor. EMBO J. 17, 2008-2018 (Pubitemid 28154530)
    • (1998) EMBO Journal , vol.17 , Issue.7 , pp. 2008-2018
    • Migliaccio, A.1    Piccolo, D.2    Castoria, G.3    Domenico, M.D.4    Bilancio, A.5    Lombardi, M.6    Gong, W.7    Beato, M.8    Auricchio, F.9
  • 10
    • 78049329473 scopus 로고    scopus 로고
    • Minireview: Role of kinases and chromatin remodeling in progesterone signaling to chromatin
    • Vicent, G. P., Nacht, A. S., Zaurín, R., Ballaré, C., Clausell, J. and Beato, M. (2010) Minireview: role of kinases and chromatin remodeling in progesterone signaling to chromatin. Mol. Endocrinol. 24, 2088-2098
    • (2010) Mol. Endocrinol. , vol.24 , pp. 2088-2098
    • Vicent, G.P.1    Nacht, A.S.2    Zaurín, R.3    Ballaré, C.4    Clausell, J.5    Beato, M.6
  • 11
    • 33847066362 scopus 로고    scopus 로고
    • Cyclin dependent kinase 2 and the regulation of human progesterone receptor activity
    • DOI 10.1016/j.steroids.2006.11.025, PII S0039128X06002601, FASEB 2006 Summer Research Conference Mechanism of Action of Steroid Hormones: Integration of Membrane and Nucleus Initiated Effects
    • Moore, N. L., Narayanan, R. and Weigel, N. L. (2007) Cyclin dependent kinase 2 and the regulation of human progesterone receptor activity. Steroids 72, 202-209 (Pubitemid 46273504)
    • (2007) Steroids , vol.72 , Issue.2 , pp. 202-209
    • Moore, N.L.1    Narayanan, R.2    Weigel, N.L.3
  • 12
    • 0023359380 scopus 로고
    • Identification and androgen regulation of two proteins released by T47D human breast cancer cells
    • Chalbos, D., Haagensen, D., Parish, T. and Rochefort, H. (1987) Identification and androgen regulation of two proteins released by T47D human breast cancer cells. Cancer Res. 47, 2787-2792
    • (1987) Cancer Res. , vol.47 , pp. 2787-2792
    • Chalbos, D.1    Haagensen, D.2    Parish, T.3    Rochefort, H.4
  • 13
    • 18144432142 scopus 로고    scopus 로고
    • Integration of progesterone receptor mediated rapid signaling and nuclear actions in breast cancer cell models: Role of mitogen-activated protein kinases and cell cycle regulators
    • DOI 10.1016/j.steroids.2005.02.012
    • Faivre, E., Skildum, A., Pierson-Mullany, L. and Lange, C. A. (2005) Integration of progesterone receptor mediated rapid signaling and nuclear actions in breast cancer cell models: role of mitogen-activated protein kinases and cell cycle regulators. Steroids 70, 418-426 (Pubitemid 40616040)
    • (2005) Steroids , vol.70 , Issue.5-7 SPEC. ISS. , pp. 418-426
    • Faivre, E.1    Skildum, A.2    Pierson-Mullany, L.3    Lange, C.A.4
  • 14
    • 44349182073 scopus 로고    scopus 로고
    • Progesterone induction of the 11β-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking
    • DOI 10.1128/MCB.01217-07
    • Subtil-Rodriguez, A., Millán-Ariño, L., Quiles, I., Ballaré, C., Beato, M. and Jordan, A. (2008) Progesterone induction of the 11β-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking. Mol. Cell. Biol. 28, 3830-3849 (Pubitemid 351732916)
    • (2008) Molecular and Cellular Biology , vol.28 , Issue.11 , pp. 3830-3849
    • Subtil-Rodriguez, A.1    Millan-Arino, L.2    Quiles, I.3    Ballare, C.4    Beato, M.5    Jordan, A.6
  • 16
    • 66449134562 scopus 로고    scopus 로고
    • Mutational analysis of progesterone receptor functional domains in stable cell lines delineates sets of genes regulated by different mechanisms
    • Quiles, I., Millán-Ariño, L., Subtil-Rodríguez, A., Miñana, B., Spinedi, N., Ballaré, C., Beato, M. and Jordan, A. (2009) Mutational analysis of progesterone receptor functional domains in stable cell lines delineates sets of genes regulated by different mechanisms. Mol. Endocrinol. 23, 809-826
    • (2009) Mol. Endocrinol. , vol.23 , pp. 809-826
    • Quiles, I.1    Millán-Ariño, L.2    Subtil-Rodríguez, A.3    Miñana, B.4    Spinedi, N.5    Ballaré, C.6    Beato, M.7    Jordan, A.8
  • 17
    • 0030898182 scopus 로고    scopus 로고
    • Identification of PRG1, a novel progestin-responsive gene with sequence homology to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
    • DOI 10.1210/me.11.4.490
    • Hamilton, J. A., Callaghan, M. J., Sutherland, R. L. and Watts, C. K. (1997) Identification of PRG1, a novel progestin-responsive gene with sequence homology to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Mol. Endocrinol. 11, 490-502 (Pubitemid 27147017)
    • (1997) Molecular Endocrinology , vol.11 , Issue.4 , pp. 490-502
    • Hamilton, J.A.1    Callaghan, M.J.2    Sutherland, R.L.3    Watts, C.K.W.4
  • 19
    • 0032461972 scopus 로고    scopus 로고
    • Molecular cloning, expression, and chromosomal localization of a ubiquitously expressed human 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase gene (PFKFB3)
    • Manzano, A., Rosa, J. L., Ventura, F., Pérez, J. X., Nadal, M., Estivill, X., Ambrosio, S., Gil, J. and Bartrons, R. (1998) Molecular cloning, expression, and chromosomal localization of a ubiquitously expressed human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene (PFKFB3). Cytogenet. Cell Genet. 83, 214-217 (Pubitemid 29112740)
    • (1998) Cytogenetics and Cell Genetics , vol.83 , Issue.3-4 , pp. 214-217
    • Manzano, A.1    Rosa, J.L.2    Ventura, F.3    Perez, J.X.4    Nadal, M.5    Estivill, X.6    Ambrosio, S.7    Gil, J.8    Bartrons, R.9
  • 22
    • 4344618856 scopus 로고    scopus 로고
    • 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: Head-to-head with a bifunctional enzyme that controls glycolysis
    • DOI 10.1042/BJ20040752
    • Rider, M. H., Bertrand, L., Vertommen, D., Michels, P. A., Rousseau, G. G. and Hue, L. (2004) 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis. Biochem. J. 381, 561-579 (Pubitemid 39120464)
    • (2004) Biochemical Journal , vol.381 , Issue.3 , pp. 561-579
    • Rider, M.H.1    Bertrand, L.2    Vertommen, D.3    Michels, P.A.4    Rousseau, G.G.5    Hue, L.6
  • 23
    • 0035146957 scopus 로고    scopus 로고
    • PFK-2/FBPase-2: Maker and breaker of the essential biofactor fructose-2,6-bisphosphate
    • DOI 10.1016/S0968-0004(00)01699-6, PII S0968000400016996
    • Okar, D. A., Manzano, A., Navarro-Sabaté, A., Riera, L., Bartrons, R. and Lange, A. J. (2001) PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate. Trends Biochem. Sci. 26, 30-35 (Pubitemid 32124707)
    • (2001) Trends in Biochemical Sciences , vol.26 , Issue.1 , pp. 30-35
    • Okar, D.A.1    Lange, A.J.2    Manzano, A.3    Navarro-Sabate, A.4    Riera, L.5    Bartrons, R.6
  • 24
    • 35448982216 scopus 로고    scopus 로고
    • Hypoxia, glucose metabolism and the Warburg's effect
    • DOI 10.1007/s10863-007-9080-3, Special Topic: The Warburg Effect: Its Continued Impact on Cancer Research into the 21st Century
    • Bartrons, R. and Caro, J. (2007) Hypoxia, glucose metabolism and the Warburg's effect. J. Bioenerg. Biomembr. 39, 223-229 (Pubitemid 47619374)
    • (2007) Journal of Bioenergetics and Biomembranes , vol.39 , Issue.3 , pp. 223-229
    • Bartrons, R.1    Caro, J.2
  • 25
    • 0031266136 scopus 로고    scopus 로고
    • Human Placental Fructose-6-phosphate,2-kinase/Fructose-2,6- bisphosphatase: Its Isozymic Form, Expression and Characterization
    • Sakakibara, R., Uemura, M., Hirata, T., Okamura, N. and Kato, M. (1997) Human placental fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase: its isozymic form, expression and characterization. Biosci. Biotechnol. Biochem. 61, 1949-1952 (Pubitemid 127471802)
    • (1997) Bioscience, Biotechnology and Biochemistry , vol.61 , Issue.11 , pp. 1949-1952
    • Sakakibara, R.1    Uemura, M.2    Hirata, T.3    Okamura, N.4    Kato, M.5
  • 27
    • 19944399717 scopus 로고    scopus 로고
    • 6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia
    • DOI 10.1074/jbc.M406096200
    • Obach, M., Navarro-Sabaté, A., Caro, J., Kong, X., Duran, J., Gómez, M., Perales, J. C., Ventura, F., Rosa, J. L. and Bartrons, R. (2004) 6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia. J. Biol. Chem. 279, 53562-53570 (Pubitemid 40051863)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.51 , pp. 53562-53570
    • Obach, M.1    Navarro-Sabate, A.2    Caro, J.3    Kong, X.4    Duran, J.5    Gomez, M.6    Perales, J.C.7    Ventura, F.8    Rosa, J.L.9    Bartrons, R.10
  • 30
    • 67349131613 scopus 로고    scopus 로고
    • Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatases in cancer
    • Yalcin, A., Telang, S., Clem, B. and Chesney, J. (2009) Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer. Exp. Mol. Pathol. 86, 174-179
    • (2009) Exp. Mol. Pathol. , vol.86 , pp. 174-179
    • Yalcin, A.1    Telang, S.2    Clem, B.3    Chesney, J.4
  • 31
    • 76249114497 scopus 로고    scopus 로고
    • E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation
    • Almeida, A., Bolaños, J. P. and Moncada, S. (2010) E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation. Proc. Natl. Acad. Sci. U.S.A. 107, 738-741
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 738-741
    • Almeida, A.1    Bolaños, J.P.2    Moncada, S.3
  • 32
    • 33746037631 scopus 로고    scopus 로고
    • PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells
    • DOI 10.1016/j.febslet.2006.04.093, PII S0014579306005758
    • Calvo, M. N., Bartrons, R., Castaño, E., Perales, J. C., Navarro-Sabaté, A. and Manzano, A. (2006) PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells. FEBS Lett. 580, 3308-3314 (Pubitemid 44251000)
    • (2006) FEBS Letters , vol.580 , Issue.13 , pp. 3308-3314
    • Calvo, M.N.1    Bartrons, R.2    Castano, E.3    Perales, J.C.4    Navarro-Sabate, A.5    Manzano, A.6
  • 33
    • 0037108709 scopus 로고    scopus 로고
    • High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase (iPFK-2; PFKFB3) in human cancers
    • Atsumi, T., Chesney, J., Metz, C., Leng, L., Donnelly, S., Makita, Z., Mitchell, R. and Bucala, R. (2002) High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers. Cancer Res. 62, 5881-5887 (Pubitemid 35204749)
    • (2002) Cancer Research , vol.62 , Issue.20 , pp. 5881-5887
    • Atsumi, T.1    Chesney, J.2    Metz, C.3    Leng, L.4    Donnelly, S.5    Makita, Z.6    Mitchell, R.7    Bucala, R.8
  • 34
    • 38049077430 scopus 로고    scopus 로고
    • 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is up-regulated in high-grade astrocytomas
    • Kessler, R., Bleichert, F., Warnke, J. P. and Eschrich, K. (2008) 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is up-regulated in high-grade astrocytomas. J. Neurooncol. 86, 257-264
    • (2008) J. Neurooncol. , vol.86 , pp. 257-264
    • Kessler, R.1    Bleichert, F.2    Warnke, J.P.3    Eschrich, K.4
  • 35
    • 0020438908 scopus 로고
    • A kinetic study of pyrophosphate: Fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose 2,6-bisphosphate
    • Van Schaftingen, E., Lederer, B., Bartrons, R. and Hers, H. G. (1982) A kinetic study of pyrophosphate: fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose 2,6-bisphosphate. Eur. J. Biochem. 129, 191-195
    • (1982) Eur. J. Biochem. , vol.129 , pp. 191-195
    • Van Schaftingen, E.1    Lederer, B.2    Bartrons, R.3    Hers, H.G.4
  • 36
    • 0000831018 scopus 로고
    • I-(+)-Lactate
    • Bergmeyer, H. U., ed., Academic Press, New York
    • Gutmann, I. and Wahlefeld, A. W. (1974) I-(+)-Lactate. In Methods of Enzymatic Analysis (Bergmeyer, H. U., ed.), pp. 1464-1468, Academic Press, New York
    • (1974) Methods of Enzymatic Analysis , pp. 1464-1468
    • Gutmann, I.1    Wahlefeld, A.W.2
  • 37
    • 55449090888 scopus 로고    scopus 로고
    • Depletion of human histone H1 variants uncovers specific roles in gene expression and cell growth
    • Sancho, M., Diani, E., Beato, M. and Jordan, A. (2008) Depletion of human histone H1 variants uncovers specific roles in gene expression and cell growth. PLoS Genet. 4, e1000227
    • (2008) PLoS Genet. , vol.4
    • Sancho, M.1    Diani, E.2    Beato, M.3    Jordan, A.4
  • 38
    • 10044281770 scopus 로고    scopus 로고
    • Rsk1 is sufficient for differentiation of PC12 cells
    • DOI 10.1128/MCB.24.24.10573-10583.2004
    • Silverman, E., Frödin, M., Gammeltoft, S. and Maller, J. L. (2004) Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells. Mol. Cell. Biol. 24, 10573-10583 (Pubitemid 39603117)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.24 , pp. 10573-10583
    • Silverman, E.1    Frodin, M.2    Gammeltoft, S.3    Maller, J.L.4
  • 39
    • 0018254898 scopus 로고
    • Nuclear mechanisms of estrogen action. Effects of estradiol and anti-estrogens on estrogen receptors and nuclear receptor processing
    • Horwitz, K. B. and McGuire, W. L. (1978) Nuclear mechanisms of estrogen action. Effects of estradiol and anti-estrogens on estrogen receptors and nuclear receptor processing. J. Biol. Chem. 253, 8185-8191 (Pubitemid 9086303)
    • (1978) Journal of Biological Chemistry , vol.253 , Issue.22 , pp. 8185-8191
    • Horwitz, K.B.1    McGuire, W.L.2
  • 40
    • 0028875925 scopus 로고
    • Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: The N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation
    • Leighton, I. A., Dalby, K. N., Caudwell, F. B., Cohen, P. T. and Cohen, P. (1995) Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation. FEBS Lett. 375, 289-293
    • (1995) FEBS Lett. , vol.375 , pp. 289-293
    • Leighton, I.A.1    Dalby, K.N.2    Caudwell, F.B.3    Cohen, P.T.4    Cohen, P.5
  • 43
    • 23844517036 scopus 로고    scopus 로고
    • Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer
    • DOI 10.1158/1078-0432.CCR-05-0149
    • Bando, H., Atsumi, T., Nishio, T., Niwa, H., Mishima, S., Shimizu, C., Yoshioka, N., Bucala, R. and Koike, T. (2005) Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer. Clin. Cancer Res. 11, 5784-5792 (Pubitemid 41170304)
    • (2005) Clinical Cancer Research , vol.11 , Issue.16 , pp. 5784-5792
    • Bando, H.1    Atsumi, T.2    Nishio, T.3    Niwa, H.4    Mishima, S.5    Shimizu, C.6    Yoshioka, N.7    Bucala, R.8    Koike, T.9
  • 44
    • 0037163076 scopus 로고    scopus 로고
    • The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase
    • DOI 10.1074/jbc.M205213200
    • Marsin, A. S., Bouzin, C., Bertrand, L. and Hue, L. (2002) The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase. J. Biol. Chem. 277, 30778-30783 (Pubitemid 34970775)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.34 , pp. 30778-30783
    • Marsin, A.-S.1    Bouzin, C.2    Bertrand, L.3    Hue, L.4
  • 46
    • 0030748651 scopus 로고    scopus 로고
    • Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades
    • DOI 10.1074/jbc.272.28.17269
    • Deprez, J., Vertommen, D., Alessi, D. R., Hue, L. and Rider, M. H. (1997) Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades. J. Biol. Chem. 272, 17269-17275 (Pubitemid 27311150)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.28 , pp. 17269-17275
    • Deprez, J.1    Vertommen, D.2    Alessi, D.R.3    Hue, L.4    Rider, M.H.5
  • 47
    • 0026730713 scopus 로고
    • Evidence for new phosphorylation sites for protein kinase C and cyclic AMP-dependent protein kinase in bovine heart 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase
    • Rider, M. H., van Damme, J., Vertommen, D., Michel, A., Vandekerckhove, J. and Hue, L. (1992) Evidence for new phosphorylation sites for protein kinase C and cyclic AMP-dependent protein kinase in bovine heart 6-phosphofructo-2- kinase/ fructose-2,6-bisphosphatase. FEBS Lett. 310, 139-142
    • (1992) FEBS Lett. , vol.310 , pp. 139-142
    • Rider, M.H.1    Van Damme, J.2    Vertommen, D.3    Michel, A.4    Vandekerckhove, J.5    Hue, L.6
  • 48
    • 0032741437 scopus 로고    scopus 로고
    • Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B
    • Bertrand, L., Alessi, D. R., Deprez, J., Deak, M., Viaene, E., Rider, M. H. and Hue, L. (1999) Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B. J. Biol. Chem. 274, 30927-30933
    • (1999) J. Biol. Chem. , vol.274 , pp. 30927-30933
    • Bertrand, L.1    Alessi, D.R.2    Deprez, J.3    Deak, M.4    Viaene, E.5    Rider, M.H.6    Hue, L.7
  • 50
    • 0142039020 scopus 로고    scopus 로고
    • Regulation of ubiquitous 6-phosphofructo-2-kinase by the ubiquitin-proteasome proteolytic pathway during myogenic C2C12 cell differentiation
    • DOI 10.1016/S0014-5793(03)00808-1
    • Riera, L., Obach, M., Navarro-Sabaté, A., Duran, J., Perales, J. C., Viñals, F., Rosa, J. L., Ventura, F. and Bartrons, R. (2003) Regulation of ubiquitous 6-phosphofructo-2-kinase by the ubiquitin-proteasome proteolytic pathway during myogenic C2C12 cell differentiation. FEBS Lett. 550, 23-29 (Pubitemid 37281351)
    • (2003) FEBS Letters , vol.550 , Issue.1-3 , pp. 23-29
    • Riera, L.1    Obach, M.2    Navarro-Sabate, A.3    Duran, J.4    Perales, J.C.5    Vinals, F.6    Rosa, J.L.7    Ventura, F.8    Bartrons, R.9


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