Sialic Acid Glycoengineering Using an Unnatural Sialic Acid for the Detection of Sialoglycan Biosynthesis Defects and On-Cell Synthesis of Siglec Ligands

ACS Chemical Biology

Volumn 10, Issue 10, 2015, Pages 2353-2363

  Büll, Christian ^a   Heise, Torben ^b   Beurskens, Daniëlle M H ^a   Riemersma, Moniek ^a   Ashikov, Angel ^a   Rutjes, Floris P J T ^b   Van Kuppevelt, Toin H ^a   Lefeber, Dirk J ^a   Den Brok, Martijn H ^a   Adema, Gosse J ^a   Boltje, Thomas J ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

SIALIC ACID; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN; SIALOGLYCOPROTEIN; TRANSFERRIN; GLYCOPROTEIN; LIGAND; MEMBRANE PROTEIN; N ACETYLNEURAMINIC ACID; POLYSACCHARIDE; PROTEIN BINDING;

ANIMAL EXPERIMENT; ARTICLE; BIOENGINEERING; CELL SURFACE; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYCLOADDITION; CYTOPLASM; ENZYME ACTIVITY; FEEDBACK SYSTEM; FEMALE; FLOW CYTOMETRY; GLYCOPROTEIN SYNTHESIS; GLYCOSYLATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING; ANIMAL; CARBOHYDRATE ANALYSIS; CHEMISTRY; JURKAT CELL LINE; PROTEIN ENGINEERING;

ANIMALS; BLOTTING, WESTERN; CARBOHYDRATE SEQUENCE; FEMALE; FLOW CYTOMETRY; GLYCOPROTEINS; HUMANS; JURKAT CELLS; LIGANDS; MEMBRANE GLYCOPROTEINS; MICE; MICROSCOPY, CONFOCAL; N-ACETYLNEURAMINIC ACID; POLYSACCHARIDES; PROTEIN BINDING; PROTEIN ENGINEERING; SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTINS;

EID: 84944739381     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.5b00501     Document Type: Article

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