Targeted delivery of a sialic acid-blocking glycomimetic to cancer cells inhibits metastatic spread

ACS Nano

Volumn 9, Issue 1, 2015, Pages 733-745

  Büll, Christian ^a   Boltje, Thomas Jan ^b   Van Dinther, Eric A W ^a   Peters, Timo ^b   De Graaf, Annemarie M A ^a   Leusen, Jeanette H W ^c   Kreutz, Martin ^a   Figdor, Carl G ^a   Den Brok, Martijn H ^a   Adema, Gosse J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

cancer; glycomimetic; metastasis; PLGA nanoparticles; sialic acids

Indexed keywords

CELLS; CYTOLOGY; DERMATOLOGY; DISEASES; NANOPARTICLES; ONCOLOGY; PATHOLOGY;

CANCER; GLYCOMIMETIC; METASTASIS; PLGA NANOPARTICLES; SIALIC ACIDS;

CARBOXYLIC ACIDS;

ANTIBODY; BIOMIMETIC MATERIAL; DRUG CARRIER; LACTIC ACID; MEMBRANE PROTEIN; N ACETYLNEURAMINIC ACID; NANOPARTICLE; P-3F(AX)-NEU5AC; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; SIALIC ACID DERIVATIVE;

ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; EXPERIMENTAL MELANOMA; FEMALE; IMMUNOLOGY; LUNG TUMOR; METASTASIS; MOUSE; PATHOLOGY; SECONDARY;

ANIMALS; ANTIBODIES; BIOMIMETIC MATERIALS; DRUG CARRIERS; FEMALE; LACTIC ACID; LUNG NEOPLASMS; MELANOMA, EXPERIMENTAL; MEMBRANE GLYCOPROTEINS; MICE; N-ACETYLNEURAMINIC ACID; NANOPARTICLES; NEOPLASM METASTASIS; POLYGLYCOLIC ACID; SIALIC ACIDS;

EID: 84921815152     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn5061964     Document Type: Article

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