Dimethyl cardamonin exhibits anti-inflammatory effects via interfering with the PI3K-PDK1-PKCα signaling pathway

Biomolecules and Therapeutics

Volumn 23, Issue 6, 2015, Pages 549-556

  Yu, Wan Guo ^a,b   He, Hao ^a,b   Yao, Jing Yun ^a,b   Zhu, Yi Xiang ^a,b   Lu, Yan Hua ^a,b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI COLLABORATIVE INNOVATION CENTER FOR BIOMANUFACTURING TECHNOLOGY   (China)

Author keywords

Dimethyl cardamonin; HMGB1; Inflammatory mediators; PI3K; PKC

Indexed keywords

ANTIINFLAMMATORY AGENT; DIMETHYL CARDAMONIN; GLYCYRRHIZIC ACID; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE C ALPHA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; GENE EXPRESSION; HMGB1 GENE; INTERLEUKIN 1BETA GENE; INTERLEUKIN 6 GENE; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR ALPHA GENE;

EID: 84944734865     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2015.048     Document Type: Article

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