Quantitative Proteome Analysis Reveals Increased Content of Basement Membrane Proteins in Arteries from Patients with Type 2 Diabetes Mellitus and Lower Levels among Metformin Users

Circulation: Cardiovascular Genetics

Volumn 8, Issue 5, 2015, Pages 727-735

  Preil, Simone A R ^a,c   Kristensen, Lars P ^a,c   Beck, Hans C ^a,c   Jensen, Pia S ^a,c   Nielsen, Patricia S ^d   Steiniche, Torben ^d   Bjørling Poulsen, Marina ^a,c   Larsen, Martin R ^b   Hansen, Maria L ^a,c   Rasmussen, Lars M ^a,c  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c Odense Patient Explorative Network   (Denmark)

^d AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

cardiovascular diseases; diabetes mellitus, type 2; extracellular matrix; metformin; muscle, smooth

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BASEMENT MEMBRANE PROTEIN; BETA 2 LAMININ; CELL PROTEIN; CHOLESTEROL; COLLAGEN TYPE 18; COLLAGEN TYPE 4; CREATININE; ENTACTIN; GLYCOLYTIC ENZYME; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; LAMININ GAMMA1; LOW DENSITY LIPOPROTEIN; MEMBRANE PROTEIN; METFORMIN; PERLECAN; PHOSPHOGLUCOMUTASE; PROTEOHEPARAN SULFATE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VIMENTIN; ANTIDIABETIC AGENT; PROTEOME;

ADULT; ARTERIAL TISSUE; ARTICLE; BLOOD PRESSURE; BODY MASS; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DIABETIC PATIENT; DIASTOLIC BLOOD PRESSURE; DRUG USE; FEMALE; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; INTERNAL MAMMARY ARTERY; INTIMA; LIQUID CHROMATOGRAPHY; MALE; MORPHOMETRICS; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYSTOLIC BLOOD PRESSURE; TANDEM MASS SPECTROMETRY; TUNICA MEDIA; AGED; BASEMENT MEMBRANE; DIABETES MELLITUS, TYPE 2; MAMMARY ARTERY; METABOLISM;

AGED; BASEMENT MEMBRANE; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; MALE; MAMMARY ARTERIES; MEMBRANE PROTEINS; METFORMIN; PROTEOME;

EID: 84944724473     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.115.001165     Document Type: Article

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