The trials and travels of tRNA

Genes and Development

Volumn 13, Issue 1, 1999, Pages 1-10

  Wolin, Sandra L ^a   Matera, A Gregory ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFER RNA;

HUMAN; INTRACELLULAR TRANSPORT; NONHUMAN; NUCLEOLUS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN RNA BINDING; REVIEW; RNA ANALYSIS; RNA TRANSLATION; RNA TRANSPORT;

EID: 0032935863     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.1.1     Document Type: Review

References (76)

1. Abelson, J., C.R. Trotta, and H. Li. 1998. tRNA splicing. J. Biol. Chem. 273: 12685-12686.
2. Anderson, J., M. Pak, L. Phan, B.A. Carlson, R. Cuesta, K. Asano, G.R. Bjork, M. Tamane, and A.G. Hinnebusch. 1998. The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. Genes & Dev. 12: 3650-3662.
3. Arts, G-J., M. Fornerod, and I.W. Mattaj. 1998a. Identification of a nuclear receptor for tRNA. Curr. Biol. 8: 305-314.
4. Arts, G-J., S. Kuersten, P. Romby, B. Ehresmann, and I.W. Mattaj. 1998b. The role of exportin-t in selective nuclear export of mature tRNA. EMBO J. (in press).
5. Becker, J., F. Melchior, V. Gerke, F.R. Bischoff, H. Ponstingl, and A. Wittinghofer. 1995. RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae. J. Biol. Chem 270: 11860-11865.
6. Bertrand, E., F. Houser-Scott, A. Kendall, R.H. Singer, and D.R. Engelke. 1998. Nucleolar localization of early tRNA processing. Genes & Dev. 12: 2463-2468.
7. Bischoff, F.R., C. Klebe, J. Kretschmer, A. Wittinghofer, and H. Ponstingl. 1994. RanGAP1 induces GTPase activity of nuclear Ras-related Ran. Proc. Natl. Acad. Sci. 91: 2587-2591.
8. Boelens, W.C., I. Palacios, and I.W. Mattaj. 1995. Nuclear retention of RNA as a mechanism for localization. RNA 1: 273-283.
9. Boguta, M., L.A. Hunter, W.C. Shen, E.C. Gillman, N.C. Martin, and A. K. Hopper. 1994. Subcellular locations of MOD5 proteins: Mapping of sequences sufficient for targeting to mitochondria and demonstration that mitochondrial and nuclear isoforms commingle in the cytosol. Mol. Cell. Biol. 14: 2298-2306.
10. Chamberlain, J.R., Y. Lee, W.S. Lane, and D.R. Engelke. 1998. Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP. Genes & Dev. 12: 1678-1690.
11. Clark, M.W. and J. Abelson. 1987. The subnuclear localization of tRNA ligase in yeast. J. Cell Biol. 105: 1515-1526.
12. Corbett, A.H., D.M. Koepp, G. Schlenstedt, M.S. Lee, A.K. Hopper, and P.A. Silver. 1995. Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import. J. Cell Biol. 130: 1017-1026.
13. Deng, J.S. and E.M. Tan. 1985. Effect of actinomycin D on the expression of nuclear antigen SS-B/La. J. Invest. Dermatol. 84: 225-228.
14. 2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae. J. Biol. Chem. 261: 9703-9709.
15. Asp dimeric precursor by a homologous component from Saccharomyces cerevisiae. J. Biol. Chem. 260: 1271-1279.
16. Evans, C.F. and D.R. Engelke. 1990. Yeast extracts for transfer RNA gene transcription and processing. Methods Enzymol. 181: 439-450.
17. Fan, H., J.L. Goodier, J.R. Chamberlain, D.R. Engelke, and R.J. Maraia. 1998. 5′ processing of tRNA precursors can be modulated by the human La antigen phosphoprotein. Mol. Cell. Biol. 18: 3201-3211.
18. Filonenko, V.V. and M.P. Deutscher. 1994. Evidence for similar structural organization of the multienzyme aminoacyl-tRNA synthetase complex in vivo and in vitro. J. Biol. Chem. 269: 17375-17378.
19. Fornerod, M., J. van Deursen, S. van Baal, A. Reynolds, D. Davis, K. Gopal Murti, J. Fransen, and G. Grosveld. 1997. The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. EMBO J. 16: 807-816.
20. Frank, D.N. and N.R. Pace. 1998. Ribonuclease P: Unity and diversity in a tRNA processing ribozyme. Annu. Rev. Biochem. 67: 153-180.
21. Furter, R., M. Snaith, D.E. Gillespie, and B.D. Hall. 1992. Endonucleolytic cleavage of a long 3′-trailer sequence in a nuclear yeast suppressor tRNA. Biochemistry 31: 10817-10824.
22. Görlich, D., M. Dabrowski, F.R. Bischoff, U. Kutay, P. Bork, E. Hartmann, S. Prehn, and E. Izaurralde. 1997. A novel class of RanGTP binding proteins. J. Cell Biol. 138: 65-80.
23. Graus, F., C. Cordon-Cardo, E. Bonfa, and K.B. Elkon. 1985. Immunohistochemical localization of La nuclear antigen in brain. Selective concentration of the La protein in neuronal nucleoli. J. Neuroimmunol. 9: 307-319.
24. Grosjean, H., Z. Szweykowska-Kulinska, Y. Motorin, F. Fasiolo, and G. Simos. 1997. Intron-dependent enzymatic formation of modified nucleosides in eukaryotic tRNAs: A review. Biochimie 79: 293-302.
25. Haselbeck, R.C. and C. Greer. 1993. Minimum intron requirements for tRNA splicing and nuclear transport in Xenopus oocytes. Biochemistry 32: 8575-8581.
26. Hellmuth, K., D.M. Lau, F.R. Bischoff, M. Kunzler, E. Hurt, and G. Simos. 1998. Yeast Los1p has properties of an exportinlike nucleocytoplasmic transport factor for tRNA. Mol. Cell. Biol. 18: 6374-6386.
27. Hopper, A.K. and N.C. Martin. 1992. Processing of yeast cytoplasmic and mitochondrial precursor tRNAs. In The molecular and cellular biology of the yeast Saccharomyces: Gene expression (ed. E.W. Jones, J.R. Pringle, and J.R. Broach), pp. 99-141. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
28. Hopper, A.K., F. Banks, and V. Evangelidis. 1978. A yeast mutant which accumulates precursor tRNAs. Cell 14: 211-219.
29. Hopper, A.K., L.D. Schultz, and R.A. Shapiro. 1980. Processing of intervening sequences: A new yeast mutant which fails to excise intervening sequences from precursor tRNAs. Cell 19: 741-751.
30. Hunter, L.A., A.L. Benko, J.P. Aris, D.R. Stanford, N.C. Martin, and A.K. Hopper. 1999. S. cerevisiae Mod5p-II contains sequences antagonistic for nuclear (nucleolar) and cytosolic locations. Genetics (in press).
31. Hurt, D.J., S.S. Wang, Y.H. Lin, and A.K. Hopper. 1987. Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing. Mol. Cell. Biol. 7: 1208-1216.
32. Izaurralde, E. and S. Adam. 1998. Transport of macromolecules between the nucleus and the cytoplasm. RNA 4: 351-364.
33. Izaurralde, E., U. Kutay, C. von Kobbe, I.W. Mattaj, and D. Görlich. 1997. The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J. 16: 6535-6547.
34. Jacobson, M.R., L.-G. Cao, K. Taneja, R.H. Singer, Y. Wang, and T. Pederson. 1997. Nuclear domains of the RNA subunit of RNase P. J. Cell Sci. 110: 829-837.
35. Kerjan, P., C. Cerini, M. Semeriva, and M. Mirande. 1994. The multienzyme complex containing nine aminoacyl-tRNA synthetases is ubiquitous from Drosophila to mammals. Biochem. Biophys. Acta 1199: 293-297.
36. Klebe, C., F.R. Bischoff, H. Ponstingl, and A. Wittinghofer. 1995. Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1. Biochemistry 34: 639-647.
37. Knapp, G., J.S. Beckmann, P.F. Johnson, S.A. Fuhrman, and J. Abelson. 1978. Transcription and processing of intervening sequences in yeast tRNA genes. Cell 14: 221-236.
38. Knapp, G., R.C. Ogden, C.L. Peebles, and J. Abelson. 1979. Splicing of yeast tRNA precursors: Structure of the reaction intermediates. Cell 18: 37-45.
39. Kutay, U., G. Lipowsky, E. Izaurralde, F.R. Bischoff, P. Schwarzmaier, E. Hartmann, and D. Görlich. 1998. Identification of a tRNA-specific nuclear export receptor. Mol. Cell 1: 359-369.
40. Lee, B., A.G. Matera, D.C. Ward, and J. Craft. 1996. Association of RNase mitochundrial RNA processing enzyme with ribonuclease P in higher ordered structures in the nucleolus: A possible coordinate role in ribosome biogenesis. Proc. Natl. Acad. Sci. 93: 11471-11476.
41. Lee, J-Y., C.E. Rohlman, L.A. Molony, and D.R. Engelke. 1991. Characterization of RPR1, an essential gene encoding the RNA component of Saccharomyces cerevisiae nuclear RNase P. Mol. Cell. Biol. 11: 721-730.
42. Li, Z. and M.P. Deutscher. 1996. Maturation pathways for E. coli tRNA precursors: A random multienzyme pathway in vivo. Cell 86: 503-512.
43. Lin-Marq, N. and S.G. Clarkson. 1998. Efficient synthesis, termination and release of RNA polymerase III transcripts in Xenopus extracts depleted of La protein. EMBO J. 17: 2033-2041.
44. Lund, E. and J.E. Dahlherg. 1998. Proofreading and aminoacylation of tRNAs prior to export from the nucleus. Science (in press).
45. Maden, B.E.H. 1998. Intracellular locations of RNA-modifying enzymes. In Modification and editing of RNA (ed. H. Grosjean and R. Benne), pp. 421-440. American Society for Microbiology, Washington, D.C.
46. Matera, A.G., M.R. Frey, K. Margelot, and S.L. Wolin. 1995. A perinucleolar compartment contains several RNA polymerase III transcripts as well as the polypyrimidine tract-binding protein, hnRNP I. J. Cell Biol. 129: 1181-1193.
47. Mattaj, I.W. and L. Englmeier. 1998. Nucleocytoplasmic transport: The soluble phase. Annu. Rev. Biochem. 67: 265-306.
48. Melton, D.A., E.M. De Robertis, and R. Cortese. 1980. Order and intracellular location of the events involved in the maturation of a spliced tRNA. Nature 284: 143-148.
49. Morrissey, J.P. and D. Tollervey. 1995. Birth of the snoRNPs: The evolution of RNase MRP and the eukaryotic pre-rRNA-processing system. Trends Biochem. Sci. 20: 78-82.
50. Motorin, Y., G. Keith, C. Simon, D. Foiret, G. Simos, E. Hurt, and H. Grosjean. 1998. The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity. RNA 4: 856-869.
51. Nishikura, K. and E.M. De Robertis. 1981. RNA processing in microinjected Xenopus oocytes. Sequential addition of base modifications in a spliced transfer RNA. J. Mol. Biol. 145: 405-120.
52. O'Connor, J.P. and C.L. Peebles. 1991. In vivo pre-tRNA processing in Saccharomyces cerevisiae. Mol. Cell. Biol. 11: 425-439.
53. Peebles, C.L., P. Gegenheimer, and J. Abelson. 1983. Precise excision of intervening sequences from precursor tRNAs by a membrane-associated yeast endonuclease. Cell 32: 525-536.
54. Popenko, V.I., J.L. Inavova, N.E. Cherny, V.V. Filonenko, S.F. Beresten, A.D. Wolfson, and L.L. Kisselev. 1994. Compartmentalization of certain components of the protein synthesis apparatus in mammalian cells. Eur. J. Cell Biol. 65: 60-69.
55. Quevillon, S., F. Agou, J.-C. Robinson, and M. Mirande. 1997. The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine. J. Biol. Chem. 272: 32573-32579.
56. Rauhut, R., P.R. Green, and J. Abelson. 1990. Yeast tRNA-splicing endonuclease is a heterotrimeric enzyme. J. Biol. Chem. 265: 18180-18184.
57. 2-dimethylguanosine -specific tRNA methyltransferase. Biochimie 77: 45-53.
58. Sarkar, S. and A.K. Hopper. 1998. tRNA nuclear export in S. cerevisiae: In situ hybridization analysis. Mol. Biol. Cell 9: 3041-3055.
59. Sharma, K., E. Fabre, H. Tekotte, H.C. Hurt, and D. Tollervey. 1996. Yeast nucleoporin mutants are defective in pre-tRNA splicing. Mol. Cell. Biol. 16:294-301.
60. Simos, G., A. Segref, F. Fasiolo, K. Hellmuth, A. Shevchenko, M. Mann, and E.C. Hurt. 1996a. The yeast Arc1p binds to tRNA and functions as a cofactor for the methionyl-and glutamyl-synthetases. EMBO J. 15: 5437-5448.
61. Simos, G., H. Tekotte, H. Grosjean, A. Segref, K. Sharma, D. Tollervey, and E.C. Hurt. 1996b. Nuclear pore proteins are involved in the biogenesis of functional tRNA. EMBO J. 15: 2270-2284.
62. Simos, G., A. Sauer, F. Fasiolo, and E.C. Hurt. 1998. A conserved domain within Arc1p delivers tRNA to aminoacyl-tRNA synthetases. Mol. Cell 1: 235-242.
63. Spinelli, S.L., S.A. Consaul, and E.M. Phizicky. 1997. A conditional lethal yeast phosphotransferase (tpt1) mutant accumulates tRNAs with a 2′-phosphate and an undermodified base at the splice junction. RNA 3: 1388-1400.
64. Stapulionis, R. and M.P. Deutscher. 1995. A channeled tRNA cycle during mammalian protein synthesis. Proc. Natl. Acad. Sci. 92: 7158-7161.
65. Stolc, V. and S. Altman. 1997. Rpp1, an essential protein subunit of nuclear RNase P required for processing of precursor tRNA and 35S precursor rRNA in Saccharomyces cerevisiae. Genes & Dev. 11: 2926-2937.
66. Tanner, N.K., M.M. Hanna, and J. Abelson. 1988. Binding interactions between yeast tRNA ligase and a precursor transfer ribonucleic acid containing two photoreactive uridine analogues. Biochemistry 27: 8852-8861.
67. met by point mutagenesis. Cell 43: 415-422.
68. Pro gene affect rate of transcription, processing, and stability of the transcripts. Cell 36: 179-187.
69. Trotta, C.R., F. Miao, E.A. Arn, S.W. Stevens, C.K. Ho, R. Rauhut, and J.N. Abelson. 1997. The yeast tRNA splicing endonuclease: A tetrameric enzyme with two active site subunits homologous to the archael tRNA endonucleases. Cell 89: 849-858.
70. Van Horn, D.J., C.J. Yoo, D. Xue, H. Shi, and S.L. Wolin. 1997. The La protein in Schizosaccharomyces pombe: A conserved yet dispensable phosphoprotein that functions in tRNA maturation. RNA 3: 1434-1443.
71. Tyr genes contain introns as a prerequisite for pseudouridine biosynthesis in the anticodon. Nucleic Acids Res. 16: 1951-1966.
72. Weis, K. 1998. Importins and exportins: How to get in and out of the nucleus. Trends Biochem. Sci. 23: 185-189.
73. Westaway, S.K. and J. Abelson. 1995. Splicing of tRNA precursors. In tRNA: Structure, biosynthesis, and function (ed. D. Soll and U.L. RajBhandary), pp. 79-92. American Society for Microbiology Press, Washington, D.C.
74. Wolfe, C.L., A.K. Hopper, and N.C. Martin. 1996. Mechanisms leading to and the consequences of altering the normal distribution of ATP(CTP):tRNA nucleotidyltransferase in yeast. J. Biol. Chem. 271: 4679-4686.
75. Yoo, C.J. and S.L. Wolin. 1997. The yeast La protein is required for the 3′ endonucleolytic cleavage that matures tRNA precursors. Cell 89: 393-402.
76. Met. Nature 300: 81-84.