Consumption of anthocyanin-rich cherry juice for 12 weeks improves memory and cognition in older adults with mild-to-moderate dementia

European Journal of Nutrition

Volumn 56, Issue 1, 2017, Pages 333-341

  Kent, Katherine ^a   Charlton, Karen ^a   Roodenrys, Steven ^a   Batterham, Marijka ^a   Potter, Jan ^b   Traynor, Victoria ^a   Gilbert, Hayley ^a   Morgan, Olivia ^a   Richards, Rachelle ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b WOLLONGONG HOSPITAL   (Australia)

Author keywords

Anthocyanin; Cherry; Cognition; Dementia

Indexed keywords

ANTHOCYANIN; ASCORBIC ACID; C REACTIVE PROTEIN; INTERLEUKIN 6; BIOLOGICAL MARKER; IL6 PROTEIN, HUMAN;

AGED; ALZHEIMER DISEASE; ARTICLE; BLOOD PRESSURE; CHERRY; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE SEVERITY; FEMALE; FLUID INTAKE; FRUIT JUICE; HUMAN; LONG TERM MEMORY; MALE; MEMORY; NEUROPROTECTION; RANDOMIZED CONTROLLED TRIAL; SHORT TERM MEMORY; SYSTOLIC BLOOD PRESSURE; THERAPY EFFECT; TREATMENT DURATION; TREATMENT OUTCOME; VITAMIN BLOOD LEVEL; ANALYSIS; BLOOD; BODY MASS; CHEMISTRY; DEMENTIA; DIET THERAPY; FOLLOW UP; FRUIT; FRUIT AND VEGETABLE JUICE; HAND STRENGTH; METABOLISM; NUTRITIONAL ASSESSMENT; PHYSIOLOGY; SWEET CHERRY;

AGED; ANTHOCYANINS; ASCORBIC ACID; BIOMARKERS; BLOOD PRESSURE; BODY MASS INDEX; C-REACTIVE PROTEIN; COGNITION; DEMENTIA; FEMALE; FOLLOW-UP STUDIES; FRUIT; FRUIT AND VEGETABLE JUICES; HAND STRENGTH; HUMANS; INTERLEUKIN-6; MALE; MEMORY; NUTRITION ASSESSMENT; PRUNUS AVIUM;

EID: 84944571175     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-015-1083-y     Document Type: Article

References (39)

1. Leather S (1995) Fruit and vegetables: consumption patterns and health consequences. Food J Hyg Rev 97:10
2. Engelhart MJ, Geerlings MI, Ruitenberg A, van Swieten JC, Hofman A, Witteman JC, Breteler MM (2002) Dietary intake of antioxidants and risk of Alzheimer disease. JAMA 287(24):3223–3229
3. Spencer JPE (2008) Flavonoids: modulators of brain function? Br J Nutr 99(E-S1):ES60–ES77. doi:10.1017/s0007114508965776
4. Somerset SM, Johannot L (2008) Dietary flavonoid sources in Australian adults. Nutr Cancer 60(4):442–449. doi:10.1080/01635580802143836
5. Macdonald R, Lovegrove JA, Chong MFF (2010) Fruit polyphenols and CVD risk: a review of human intervention studies. Br J Nutr 104(S3):S28–S39
6. Notas G, Nifli AP, Castanas E, Kampa M (2007) Polyphenols and cancer cell growth, vol 159. Springer, Berlin, Heidelberg, pp 79–113
7. Vauzour D, Rendeiro C, Spencer JPE (2009) Flavonoids and cognition: the molecular mechanisms underlying their behavioural effects. Arch Biochem Biophys 492(1–2):1–9
8. Spencer JPE (2010) The impact of fruit flavonoids on memory and cognition. Br J Nutr 104(S3):S40–S47. doi:10.1017/s0007114510003934
9. Vauzour D, Rodriguez-Mateos A, Corona G, Oruna-Concha MJ, Spencer JPE (2010) Polyphenols and human health: prevention of disease and mechanisms of action. Nutrients 2(11):1106–1131. doi:10.3390/nu2111106
10. Vauzour D, Vafeiadou K, Rodriguez-Mateos A, Rendeiro C, Spencer JPE (2008) The neuroprotective potential of flavonoids: a multiplicity of effects. Genes Nutr 3(3):115–126. doi:10.1007/s12263-008-0091-4
11. Krikorian R, Shidler MD, Nash TA, Kalt W, Vinqvist-Tymchuk MR, Shukitt-Hale B, Joseph JA (2010) Blueberry supplementation improves memory in older adults. J Agric Food Chem 58(7):3996–4000. doi:10.1021/jf9029332
12. Krikorian R, Nash TA, Shidler MD, Shukitt-Hale B, Joseph JA (2010) Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. Br J Nutr 103(5):730–734. doi:10.1017/s0007114509992364
13. Krikorian R, Boespflug EL, Fleck DE, Stein AL, Wightman JD, Shidler MD, Sadat-Hossieny S (2012) Concord grape juice supplementation and neurocognitive function in human aging. J Agric Food Chem 60(23):5736–5742. doi:10.1021/jf300277g
14. USDA (2013) United States Department of Agriculture Database for the flavonoid content of selected foods. Release 3:1
15. Lang GA, Mulabagal V, DeWitt DL, Nair MG, Dalavoy SS (2009) Anthocyanin content, lipid peroxidation and cyclooxygenase enzyme inhibitory activities of sweet and sour cherries. J Agric Food Chem 57(4):1239–1246
16. Bondonno CP, Swinny E, Mubarak A, Hodgson JM, Downey LA, Croft KD, Scholey A, Stough C, Yang X, Considine MJ, Ward NC, Puddey IB (2014) The acute effect of flavonoid-rich apples and nitrate-rich spinach on cognitive performance and mood in healthy men and women. Food Funct 5(5):849–858. doi:10.1039/c3fo60590f
17. Williams RJ, Spencer JPE (2012) Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease. Free Radic Bio Med 52(1):35–45. doi:10.1016/j.freeradbiomed.2011.09.010
18. Jorm AF, Dear KBG, Burgess NM (2005) Projections of future numbers of dementia cases in Australia with and without prevention. Aust N Z J Psychiatry 39(11–12):959. doi:10.1111/j.1440-1614.2005.01713.x
19. Caldwell K, Charlton KE, Roodenrys S, Jenner A (2015) Anthocyanin-rich cherry juice does not improve acute cognitive performance on RAVLT. Nutr Neurosci. doi:10.1179/1476830515Y.0000000005
20. Iland PG, Cynkar W, Francis IL, Williams PJ, Coombe BG (1996) Optimisation of methods for the determination of total and red free glycosyl-glucose in black grape berries of Vitus vinifera. Aust J Grape Wine Res 2:171–178
21. Cereda E (2012) Mini nutritional assessment. Curr Opin Clin Nutr Metab Care 15(1):29–41. doi:10.1097/MCO.0b013e32834d7647
22. Graf C (2008) The Lawton instrumental activities of daily living scale. Am J Nurs 108(4):52–62. doi:10.1097/01.naj.0000314810.46029.74
23. Mary CT, Alvaro N, Snow WG, Rory HF, Maria LZ, David WR (1994) Use of the Rey Auditory Verbal Learning Test in differentiating normal aging from Alzheimer’s and Parkinson’s Dementia. Psychol Assess 6(2):129. doi:10.1037/1040-3590.6.2.129
24. Schoenberg MR, Dawson KA, Duff K, Patton D, Scott JG, Adams RL (2006) Test performance and classification statistics for the Rey Auditory Verbal Learning Test in selected clinical samples. Arch Clin Neuropsychol 21(7):693–703. doi:10.1016/j.acn.2006.06.010
25. Ross TP, Hanouskova E, Giarla K, Calhoun E, Tucker M (2007) The reliability and validity of the self-ordered pointing task. Arch Clin Neuropsychol 22(4):449–458. doi:10.1016/j.acn.2007.01.023
26. Calero MD, Arnedo ML, Elena N, Monica R-P, Cristobal C (2002) Usefulness of a 15-item version of the Boston Naming Test in neuropsychological assessment of low-educational elders with dementia. J Gerontol 57B(2):P187
27. Rasmusson DX, Zonderman AB, Kawas C, Resnick SM (1998) Effects of age and dementia on the trail making test. Clin Neuropsychol 12(2):169–178. doi:10.1076/clin.12.2.169.2005
28. Gliko BT, Espe-Pfeifer P, Selden J, Escalona A, Golden CJ (2000) Validity of Digit Span as a test for memory in dementia. Arch Clin Neuropsychol 15(8):737. doi:10.1016/s0887-6177(00)80162-6
29. Pasquier F, Lebert F, Grymonprez L, Petit H (1995) Verbal fluency in dementia of frontal lobe type and dementia of Alzheimer type. J Neurol Neurosurg Psychiatry 58(1):81–84. doi:10.1136/jnnp.58.1.81
30. Paradela EMP, Lourenço RA, Veras RP (2005) Validation of geriatric depression scale in a general outpatient clinic. Rev Saude Publica 39(6):918–923
31. Cohen J (1988) Statistical power analysis for the behavioral sciences. Erlbaum Associates, Hillsdale
32. Shukitt-Hale B, Carey A, Simon L, Mark DA, Joseph JA (2006) Effects of concord grape juice on cognitive and motor deficits in aging. Nutrition 22(3):295–302. doi:10.1016/j.nut.2005.07.016
33. Shukitt-Hale B, Cheng V, Joseph JA (2009) Effects of blackberries on motor and cognitive function in aged rats. Nutr Neurosci 12(3):135–140. doi:10.1179/147683009X423292
34. Galli RL, Shukitt-Hale B, Youdim KA, Joseph JA (2002) Fruit polyphenolics and brain aging: nutritional interventions targeting age-related neuronal and behavioral deficits. Ann N Y Acad Sci 959(1):128–132. doi:10.1111/j.1749-6632.2002.tb02089.x
35. Johannot L, Somerset SM (2006) Age-related variations in flavonoid intake and sources in the Australian population. Public Health Nutr 9(8):1045–1054
36. Williamson G, Holst B (2008) Dietary reference intake (DRI) value for dietary polyphenols: are we heading in the right direction? Br J Nutr 99(Suppl 3):S55–S58. doi:10.1017/S0007114508006867
37. Devore EE, Grodstein F, van Rooij FJ, Hofman A, Stampfer MJ, Witteman JC, Breteler MM (2010) Dietary antioxidants and long-term risk of dementia. Arch Neurol-Chicago 67(7):819–825. doi:10.1001/archneurol.2010.144
38. Egert S, Rimbach G (2011) Which sources of flavonoids: complex diets or dietary supplements? Adv Nutr 2(1):8–14
39. Willis LM, Shukitt-Hale B, Joseph JA (2009) Recent advances in berry supplementation and age-related cognitive decline. Curr Opin Clin Nutr Metab Care 12(1):91–94. doi:10.1097/MCO.0b013e32831b9c6e