Macrophages in human colorectal cancer are pro-inflammatory and prime T cells towards an anti-tumour type-1 inflammatory response

European Journal of Immunology

Volumn 42, Issue 1, 2012, Pages 89-100

  Ong, Siew Min ^a   Tan, Yann Chong ^a   Beretta, Ottavio ^a   Jiang, Dongsheng ^b   Yeap, Wei Hseun ^a   Tai, June J Y ^a   Wong, Wing Cheong ^c   Yang, Henry ^a   Schwarz, Herbert ^b   Lim, Kiat Hon ^d   Koh, Poh Koon ^d   Ling, Khoon Lin ^d   Wong, Siew Cheng ^a  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c BIOINFORMATICS INSTITUTE   (Singapore)

^d SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

Chemokines; Cytokines; Spheroid model; T cell co stimulation; Tumour associated macrophages (TAMs)

Indexed keywords

ANTIGEN; CHEMOKINE;

ARTICLE; CELL INFILTRATION; CELL PROLIFERATION; COLORECTAL CANCER; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR IMMUNITY; TYPE 1 T CELL;

COCULTURE TECHNIQUES; COLORECTAL NEOPLASMS; CYTOKINES; GENE EXPRESSION PROFILING; HT29 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOCYTES, TUMOR-INFILTRATING; MACROPHAGES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TH1 CELLS;

EID: 84855219213     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141825     Document Type: Article

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