From phagocyte diversity and activation to probiotics: Back to Metchnikoff

European Journal of Immunology

Volumn 38, Issue 12, 2008, Pages 3269-3273

  Mantovani, Alberto ^a,b  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

M1 M2 polarization; Macrophage activation; Macrophages; Probiotics

Indexed keywords

PROBIOTIC AGENT;

ADAPTIVE IMMUNITY; BONE MARROW CELL; CELL DIFFERENTIATION; CELL HETEROGENEITY; CELL POLARITY; HOST RESISTANCE; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; IMMUNOPATHOLOGY; IMMUNOREACTIVITY; INNATE IMMUNITY; LACTOBACILLUS; MACROPHAGE ACTIVATION; MONONUCLEAR PHAGOCYTE; NONHUMAN; NOTE; PHAGOCYTE; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; SUPPRESSOR CELL; TISSUE REPAIR; ADAPTATION; ANIMAL; CYTOLOGY; DRUG EFFECT; IMMUNOLOGY; MACROPHAGE;

ADAPTATION, BIOLOGICAL; ANIMALS; CELL DIFFERENTIATION; HUMANS; MACROPHAGES; MYELOID CELLS; PHAGOCYTES; PROBIOTICS;

EID: 59749084216     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838918     Document Type: Note

References (56)

1. Gordon, S., Elie Metchnikoff - father of natural immunity. Eur. J. Immunol. 2008. In press.
2. Gordon, S., Alternative activation of macrophages. Nat. Rev. Immunol. 2003. 3: 23-35.
3. Gordon, S. and Taylor, P. R., Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 2005. 5: 953-964.
4. Silverstein, A. M., The historical origins of modern immunology, in: Gallagher, R. B., Gilder, J., Nossal, G. J. V., Salvatore, G. (Eds.), Immunology. The Making of a Modern Science, Academic Press, London 1995, pp. 5-20.
5. Sica, A. and Bronte, V., Altered macrophage differentiation and immune dysfunction in tumor development. J. Clin. Invest. 2007. 117: 1155-1166.
6. Bunt, S. K., Yang, L., Sinha, P., Clements, V. K., Leips, J. and Ostrand-Rosenberg, S., Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression. Cancer Res. 2007. 67: 10019-10026.
7. Nagaraj, S. and Gabrilovich, D. I., Tumor escape mechanism governed by myeloid-derived suppressor cells. Cancer Res. 2008. 68: 2561-2563.
8. Scapini, P., Bazzoni, F. and Cassatella, M. A., Regulation of B-cell-activating factor (BAFF)/B lymphocyte stimulator (BLyS) expression in human neutrophils. Immunol. Lett. 2008. 116: 1-6.
9. Mantovani, A., Allavena, P., Sica, A. and Balkwill, F., Cancer-related inflammation. Nature 2008. 454: 436-444.
10. Kusmartsev, S. and Gabrilovich, D. I., STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion. J. Immunol. 2005. 174: 4880-4891.
11. Kusmartsev, S., Nagaraj, S. and Gabrilovich, D. I., Tumor-associated CD8+T cell tolerance induced by bone marrow-derived immature myeloid cells. J. Immunol. 2005. 175: 4583-4592.
12. De Palma, M., Murdoch, C., Venneri, M. A., Naldini, L. and Lewis, C. E., Tie2-expressing monocytes: Regulation of tumor angiogenesis and therapeutic implications. Trends Immunol. 2007. 28: 519-524.
13. Movahedi, K., Guilliams, M., Van den Bossche, J., Van den Bergh, R., Gysemans, C., Beschin, A., De Baetselier, P. and Van Ginderachter, J. A., Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood 2008. 111: 4233-4244.
14. Biswas, S. K., Gangi, L., Paul, S., Schioppa, T., Saccani, A., Sironi, M., Bottazzi, B. et al., A distinct and unique transcriptional programme expressed by tumor-associated macrophages: defective NF-κB and enhanced IRF-3/STAT1 activation. Blood 2006. 107: 2112-2122.
15. Ghassabeh,G.H., De Baetselier, P., Brys, L., Noel,W., VanGinderachter, J. A., Meerschaut, S., Beschin, A. et al., Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions. Blood 2006. 108: 575-583.
16. Mantovani, A., Sozzani, S., Locati, M., Allavena, P. and Sica, A., Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 2002. 23: 549-555.
17. Mantovani, A., Sica, A., Sozzani, S., Allavena, P., Veechi, A. and Locati, M., The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004. 25: 677-686.
18. Mantovani, A., Sica, A. and Locati, M., New vistas on Macrophage differentiation and activation. Eur. J. Immunol. 2007. 37: 14-16.
19. Goerdt, S. and Orfanos, C. E., Other functions, other genes: alternative activation of antigen-presenting cells. Immunity 1999. 10: 137-142.
20. Mosser, D. M., The many faces of macrophage activation. J. Leukoc. Biol. 2003. 73: 209-212.
21. Mills, C. D., Kincaid, K., Alt, J. M., Heilman, M. J. and Hill, A. M., M-1/M-2 macrophages and the Th1/Th2 paradigm. J. Immunol. 2000. 164: 6166-6173.
22. Martinez, F. O., Gordon, S., Locati, M. and Mantovani, A., Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression. J. Immunol. 2006. 177: 7303-7311.
23. Hamilton, J. A., Colony-stimulating factors in inflammation and auto-immunity Nat. Rev. Immunol. 2008. 8: 533-544.
24. Xu, W., Schlagwein, N., Roos, A., van den Berg, T. K., Daha, M. R. and van Kooten, C., Human peritoneal macrophages show functional characteristics of M-CSF-driven anti-inflammatory type 2 'macrophage. Eur. J. Immunol. 2007. 37: 1594-1599.
25. Ludwiczek, S., Aigner, E., Theurl, I. and Weiss, G., Cytokine-mediated regulation of iron transport human monocyte cells. Blood 2003. 101: 4148-4154.
26. Savage, N. D., de Boer, T., Walburg, K. V., Joosten, S. A., van Meijgaarden, K., Geluk, A. and Ottenhoff, T. H., Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1. J. Immunol. 2008. 181: 2220-2226.
27. Tiemessen, M. M., Jagger, A. L., Evans, H. G., van Herwijnen, M. J., John, S. and Taams, L. S., CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages. Proc. Natl. Acad. Sci. USA 2007. 104: 19446-19451.
28. Rae, F., Woods, K., Sasmono, T., Campanale, N., Taylor, D., Ovchinnikov, D. A., Grimmond, S. M. et al., Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter. Dev. Biol. 2007. 308: 232-246.
29. Bourlier, V., Zakaroff-Girard, A., Miranville, A., De Barros, S., Maumus, M., Sengenes, C., Galitzky, J. et al., Remodeling phenotype of human subcutaneous adipose tissue macrophages. Circulation 2008. 117: 806-815.
30. Coates, P. J., Rundle, J. K., Lorimore, S. A. and Wright, E. G., Indirect macrophage responses to ionizing radiation: Implications for genotype-dependent bystander signaling. Cancer Res. 2008. 68: 450-456.
31. Kelly, J., Ali Khan, A., Yin, J., Ferguson, T. A. and Apte, R. S., Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice. J. Clin. Invest. 2007. 117: 3421-3426.
32. Swirski, F. K., Libby, P., Aikawa, E., Alcaide, P., Luscínskas, F. W., Weissleder, R. and Pittet, M. J., Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata. J. Clin. Invest. 2007. 117: 195-205.
33. Lumeng, C. N., Bodzin, J. L. and Saltiel, A. R., Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Invest. 2007. 117: 175-184.
34. Trujillo, G., O'Connor, E. C., Kunkel, S. L. and Hogaboam, C. M., A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis. Am. J. Pathol. 2008. 172: 1209-1221.
35. Reese, T. A., Liang, H. E., Tager, A. M., Luster, A. D., Van Rooijen, N., Voehringer, D. and Locksley, R. M., Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 2007. 447: 92-96.
36. Odegaard, J. I., Ricardo-Gonzalez, R. R., Goforth, M. H., Morel, C. R., Subramanian, V., Mukundan, L., Eagle, A. R. et al., Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature 2007. 447: 1116-1120.
37. Cihakova, D., Barin, J. G., Afanasyeva, M., Kimura, M., Fairweather, D., Berg, M., Talor, M. V. et al., Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation. Am. J. Pathol. 2008. 172: 1195-1208.
38. Kamada, N., Hisamatsu, T., Okamoto, S., Chinen, H., Kobayashi, T., Sato, T., Sakuraba, A. et al., Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis. J. Clin. Invest. 2008. 118: 2269-2280.
39. Weber, M. S., Prod'homme, T., Youssef, S., Dunn, S. E., Rundle, C. D., Lee, L., Patarroyo, J. C. et al., Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nat. Med. 2007. 13: 935-943.
40. Clark, R. A. and Kupper, T. S., Misbehaving macrophages in the pathogenesis of psoriasis. J. Clin. Invest. 2006. 116: 2084-2087.
41. Wynn, T. A., Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat. Rev. Immunol. 2004. 4: 583-594.
42. Bystrom, J., Evans, I., Newson, J., Stables, M., Toor, I., van Rooijen, N., Crawford, M. et al., Resolution-phase macrophages possess a unique inflammatory and bactericidal phenotype that is controlled by cAMP. Blood 2008. In press.
43. Benoit, M., Desnues, B. and Mege, J. L., Macrophage polarization in bacterial infections. J. Immunol. 2008. 181: 3733-3739.
44. Glasser, S. W., Senft, A. P., Whitsett, J. A., Maxfield, M. D., Ross, G. F., Richardson, T. R., Prows, D. R. et al., Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice. J. Immunol. 2008. 181: 621-628.
45. Ness, T. L., Ewing, J. L., Hogaboam, C. M. and Kunkel, S. L., CCR4 is a key modulator of innate immune responses. J. Immunol. 2006. 177: 7531-7539.
46. Benoit, M., Barbarat, B., Bernard, A., Olive, D. and Mege, J. L., Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages. Eur. J. Immunol. 2008. 38: 1065-1070.
47. Shirey, K. A., Cole, L. E., Keegan, A. D. and Vogel, S. N., Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism. J. Immunol. 2008. 181: 4159-4167.
48. Kim, E. Y., Battaile, J. T., Patel, A. C., You, Y., Agapov, E., Grayson, M. H., Benoit, L. A. et al., Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat. Med. 2008. 14: 633-640.
49. Meghari, S., Berruyer, C., Lepidi, H., Galland, F., Naquet, P. and Mege, J. L., Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection. Eur. J. Immunol. 2007. 37: 24-32.
50. Raes, G., Beschin, A., Ghassabeh, G. H. and De Baetselier, P., Alternatively activated macrophages in protozoan infections. Curr. Opin. Immunol. 2007. 19: 454-459.
51. Anthony, R. M., Urban, J. F., Jr., Alem, F., Hamed, H. A., Rozo, C. T., Boucher, J. L., Van Rooijen, N. and Gause, W. C., Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nat. Med. 2006. 12: 955-960.
52. Weng, M., Huntley, D., Huang, I. F., Foye-Jackson, O., Wang, L., Sarkissian, A., Zhou, Q. et al., Alternatively activated macrophages in intestinal helminth infection: Effects on concurrent bacterial colitis. J. Immunol. 2007. 179: 4721-4731.
53. Marsland, B. J., Kurrer, M., Reissmann, R., Harris, N. L. and Kopf, M., Nippostrongylus brasiliensis infection leads to the development of emphysema associated with the induction of alternatively activated macrophages. Eur. J. Immunol. 2008. 38: 479-488.
54. Auffracy C., Fogg, D., Garfa, M., Elain, G. Join-Lambert, O., Kayal, S., Sarnacki, S. et al., Monitoring of blood vessels and tissues by a population of monocytes with patrolling behaviour. Science 2007. 317: 666-670.
55. Bowdish, D. M., Loffredo, M. S., Mukhopadhyay, S., Mantovani, A. and Gordon, S., Macrophage receptors implicated in the "adaptive" form of innate immunity. Microbes Infect. 2007. 9: 1680-1687.
56. Hickson, M., D'Souza, A. L., Muthu, N., Rogers, T. R., Want, S., Rajkumar, C. and Bulpitt, C. J., Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: Randomised double blind placebo controlled trial. BMJ 2007. 335: 80.