Mechanism of chemoprevention against colon cancer cells using combined Gelam honey and Ginger extract via mTOR and Wnt/β-catenin pathways

Asian Pacific Journal of Cancer Prevention

Volumn 16, Issue 15, 2015, Pages 6549-6556

  Wee, Lee Heng ^a,b   Morad, Noor Azian ^a,b   Aan, Goon Jo ^a,b   Makpol, Suzana ^a,b   Wan Ngah, Wan Zurinah ^a,b   Yusof, Yasmin Anum Mohd ^a,b  

^a DEPARTMENT OF PHARMACOLOGY   (Malaysia)

^b MALAYSIA JAPAN INTERNATIONAL INSTITUTE OF TECHNOLOGY   (Malaysia)

Author keywords

Apoptosis; Combination; HT29 colon cancer cells; mTOR; Wnt catenin

Indexed keywords

ANTINEOPLASTIC AGENT; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; BETA CATENIN; CARRIER PROTEIN; CASPASE 3; CYCLIN D1; CYTOCHROME C; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MTOR PROTEIN, HUMAN; PLANT EXTRACT; PROTEIN KINASE B; RICTOR PROTEIN, HUMAN; RPTOR PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TARGET OF RAPAMYCIN KINASE; TCF4 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

APOPTOSIS; CELL SURVIVAL; CHEMOPROPHYLAXIS; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECTS; GENE EXPRESSION; GENETICS; GINGER; HONEY; HT 29 CELL LINE; HUMAN; IC50; MELALEUCA; METABOLISM; UPREGULATION; WNT SIGNALING PATHWAY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTICARCINOGENIC AGENTS; APOPTOSIS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BETA CATENIN; CARRIER PROTEINS; CASPASE 3; CELL SURVIVAL; CHEMOPREVENTION; CYCLIN D1; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GENE EXPRESSION; GINGER; GLYCOGEN SYNTHASE KINASE 3; HONEY; HT29 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MELALEUCA; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; TOR SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS; UP-REGULATION; WNT SIGNALING PATHWAY;

EID: 84944463387     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2015.16.15.6549     Document Type: Article

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