Molecular dynamics study of segment peptides of Bax, Bim, and Mcl-1 BH3 domain of the apoptosis-regulating proteins bound to the anti-apoptotic Mcl-1 protein

Journal of Biomolecular Structure and Dynamics

Volumn 33, Issue 5, 2015, Pages 1067-1081

  Zhao, Run Ning ^a   Fan, Song ^b   Han, Ju Guang ^c   Liu, Guang ^c  

^a SHANGHAI DIANJI UNIVERSITY   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

anti apoptotic Mcl 1 protein; apoptosis regulating proteins; free energy; hydrophobic residues; Mcl 1 BH3 domain; molecular dynamics simulation

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; ARGININE; ASPARTIC ACID; BH3 PROTEIN; BIM PROTEIN; GLYCINE; ISOLEUCINE; LEUCINE; LYSINE; PROTEIN BAX; PROTEIN MCL 1; VALINE; BCL-2-LIKE PROTEIN 11; MCL1 PROTEIN, HUMAN; MEMBRANE PROTEIN; ONCOPROTEIN; PEPTIDE; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; HYDROPHOBICITY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; BINDING COMPETITION; CHEMICAL PHENOMENA; CHEMISTRY; GENETICS; HUMAN; HYDROGEN BOND; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS;

AMINO ACID SEQUENCE; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BINDING, COMPETITIVE; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MEMBRANE PROTEINS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; THERMODYNAMICS;

EID: 84944457461     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2014.929028     Document Type: Article

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