Kinin B1 receptor antagonist BI113823 reduces acute lung injury

Critical Care Medicine

Volumn 43, Issue 11, 2015, Pages e499-e507

  Nasseri, Saeed ^a   Gurusamy, Malarvizhi ^a   Jung, Birgit ^b   Lee, Dongwon ^a   Khang, Gilson ^a   Doods, Henri ^b   Wu, Dongmei ^a,c  

^a Chonbuk National University   (South Korea)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

Acute lung injury; Kinin B1 receptor; Leukocyte infiltration; Vascular permeability

Indexed keywords

BI 113823; BRADYKININ B1 RECEPTOR ANTAGONIST; CYCLOOXYGENASE 2; DEXAMETHASONE; ENDOTOXIN; I KAPPA B KINASE ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; BRADYKININ; CYTOKINE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; EXPERIMENTAL STUDY; HISTOLOGY; INFLAMMATORY CELL; LUNG FLUID; LUNG LAVAGE; LUNG PARENCHYMA; MACROPHAGE; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; PUNCTURE; RAT; SEPSIS; WATER CONTENT; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BRONCHOALVEOLAR LAVAGE FLUID; COMPARATIVE STUDY; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; IMMUNOHISTOCHEMISTRY; METABOLISM; MORTALITY; MOUSE; PATHOPHYSIOLOGY; RANDOMIZATION; REFERENCE VALUE; SURVIVAL RATE; TREATMENT OUTCOME; WESTERN BLOTTING; WISTAR RAT;

ACUTE LUNG INJURY; ANIMALS; BLOTTING, WESTERN; BRADYKININ; BRONCHOALVEOLAR LAVAGE FLUID; CYCLOOXYGENASE 2; CYTOKINES; DEXAMETHASONE; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; RANDOM ALLOCATION; RATS; RATS, WISTAR; REFERENCE VALUES; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84944454814     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000001268     Document Type: Article

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