Mechanisms of the beneficial effect of NHE1 inhibitor in traumatic hemorrhage: Inhibition of inflammatory pathways

Resuscitation

Volumn 83, Issue 6, 2012, Pages 774-781

  Wu, Dongmei ^a,b   Qi, Jiansong ^a  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b Chonbuk National University   (South Korea)

Author keywords

Inflammatory response; Myocardial dysfunction; Organ injury; Traumatic hemorrhagic shock

Indexed keywords

[4 [4 (2 FUROYL) 1 PIPERAZINYL] 3 (METHYLSULFONYL)BENZOYL]GUANIDINE; HETASTARCH; I KAPPA B KINASE BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE SYNTHASE; PROTEIN INHIBITOR; SODIUM PROTON EXCHANGE PROTEIN;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FLUID RESUSCITATION; GENE EXPRESSION; HEART INDEX; HEART MUSCLE CONTRACTURE; HEART MUSCLE INJURY; HEART STROKE VOLUME; HEMORRHAGIC SHOCK; HEPATIC ARTERY; INFLAMMATION; KIDNEY INJURY; LIVER INJURY; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SWINE; TIBIA FRACTURE;

ANIMALS; FLUID THERAPY; HEMODYNAMICS; HETASTARCH; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-6; MALE; MAP KINASE SIGNALING SYSTEM; MESYLATES; MULTIPLE ORGAN FAILURE; MYOCARDIAL ISCHEMIA; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PLASMA SUBSTITUTES; RESUSCITATION; SHOCK, HEMORRHAGIC; SODIUM-HYDROGEN ANTIPORTER; SUS SCROFA; TROPONIN I;

EID: 84860469840     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2011.11.025     Document Type: Article

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