Kinin B 1 receptors: Key G-protein-coupled receptors and their role in inflammatory and painful processes

British Journal of Pharmacology

Volumn 143, Issue 7, 2004, Pages 803-818

  Calixto, João B ^a   Medeiros, Rodrigo ^a   Fernandes, Elizabeth S ^a   Ferreira, Juliano ^a   Cabrini, Daniela A ^a   Campos, Maria M ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

B 1 receptors; Inflammation; Kinins; Pain; Selective antagonists

Indexed keywords

ACETYLLYSYLBRADYKININ[7 [3 (2 NAPHTHYL)ALANINE] 8 ISOLEUCINE 9 DEARGININE]; B 9958; BENZODIAZEPINE RECEPTOR BLOCKING AGENT; BRADYKININ; BRADYKININ B1 RECEPTOR; BRADYKININ B1 RECEPTOR AGONIST; BRADYKININ B1 RECEPTOR ANTAGONIST; BRADYKININ B2 RECEPTOR; BRADYKININ[8 LEUCINE 9 DEARGININE]; BREFELDIN A; COMPLEMENTARY DNA; CYCLOHEXIMIDE; CYCLOPHOSPHAMIDE; DACTINOMYCIN; DEXAMETHASONE; DIHYDROQUINOXALINONE ANTAGONIST; G PROTEIN COUPLED RECEPTOR; I KAPPA B KINASE; ICATIBANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSYLBRADYKININ[8 LEUCINE 9 DEARGININE]; LYSYLLYSYLARGINYLPROLYL(4 HYDROXYPROLYL)GLYCYL 2 (2,3 DIHYDRO 1H INDEN 2 YL)GLYCYLSERYL 2 (2,3 DIHYDRO 1H INDEN 2 YL)GLYCYLOCTAHYDRO 1H INDOLE 2 CARBOXYLIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; R 954; SSR 240612; TOLL LIKE RECEPTOR; TUNICAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL MODEL; ARTHRITIS; ASTHMA; CANCER; CYSTITIS; DIABETES MELLITUS; DISEASE MODEL; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ENZYME INHIBITION; HEART MUSCLE ISCHEMIA; INFECTION; INFLAMMATION; KNOCKOUT MOUSE; MOUSE; NEUROPATHIC PAIN; NONHUMAN; PAIN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; REVIEW; RNA INTERFERENCE; RNA TRANSCRIPTION; STREPTOZOCIN DIABETES; TRYPANOSOMA CRUZI; ANIMAL; CHEMISTRY; GENETICS; HUMAN; PHYSIOLOGY; UPREGULATION;

ANIMALS; HUMANS; INFLAMMATION; PAIN; RECEPTOR, BRADYKININ B1; RECEPTORS, G-PROTEIN-COUPLED; UP-REGULATION;

EID: 10844228161     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706012     Document Type: Review

References (181)

1. 1 receptors in retinal microvessels of the streptozotocin-diabetic rats. Br. J. Pharmacol, 140, 33-40.
2. 1 receptors as a new inflammatory target. Could this B the 1? Trends Pharmacol. Sci., 20, 100-104.
3. AKIRA, S., YAMAMOTO, M. & TAKEDA, K. (2003). Role of adapters in Toll-like receptor signalling. Biochem. Soc. Trans., 31, 637-642.
4. 1 receptor gene promoter: no modification on interleukin-1 beta or lypopolysaccharide induction. J. Cell. Biochem., 78, 278-296.
5. BACHAR, O., ADNER, M., UDDMAN, R. & CARDELL, L.O. (2004). Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappaB signaling pathways. Eur. J. Immunol., 34, 1196-1207.
6. 1 receptor gene for kinins (BDKRB1). Genomics, 33, 374-381.
7. 2 kinin receptors for the proliferation of androgen-insensitive prostate cancer PC3 cells. Biochem. J., 371, 581-587.
8. BEG, A.A. (2002). Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends Immunol., 23, 509-512.
9. BEIRITH, A., SANTOS, A.R. & CALIXTO, J.B. (2003). The role of neuropeptides and capsaicin-sensitive fibres in glutamate-induced nociception and paw oedema in mice. Brain Res., 969, 110-116.
10. BÉLICHARD, P., LANDRY, M., FAYE, P., BACHVAROV, D.R., BOUTHILLIER, J., PRUNEAU, D. & MARCEAU, F. (2000). Inflammatory hyperalgesia induced by zymosan in the plantar tissue of the rat: effect of kinin receptor antagonists. Immunopharmacology, 46, 139-147.
11. BELICHARD, P., LUCCARINI, J.M., DEFRENE, E., FAYE, P., FRANCK, R.M., DUCOS, H., PAQUET, J.L. & PRUNEAU, D. (1999). Pharmacological and molecular evidence for kinin expression in urinary bladder of cyclophosphamide-treated rats. Br. J. Pharmacol., 128, 213-219.
12. BHOOLA, K.D., RAMSAROOP, R., PLENDL, J., CASSIM, B., DLAMINI, Z. & NAICKER, S. (2001). Kallikrein and kinin receptor expression in inflammation and cancer. Biol. Chem., 382, 77-89.
13. BOCK, M.G. & LONGMORE, J. (2000). Bradykinin antagonists: new opportunities. Curr. Opin. Chem. Biol., 4, 401-406.
14. 2 bradykinin receptor gene in mice eliminates bradykinin action in smooth muscle and neurons. J. Biol. Chem., 270, 13706-13710.
15. 1 receptors in rat dorsal root ganglion neurons. NeuroReport, 12, 3165-3168.
16. 9-bradykinin-induced contraction in guinea-pig gallbladder in vitro. Eur. J. Pharmacol., 331, 31-38.
17. 1 receptor expression by endogenous glucocorticoids hormones in rats. Br. J. Pharmacol., 132, 567-577.
18. CALIXTO, J.B., CABRINI, D.A., FERREIRA, J. & CAMPOS, M.M. (2000). Kinins in pain and inflammation. Pain, 87, 1-5.
19. CALIXTO, J.B., CABRINI, D.A., FERREIRA, J. & CAMPOS, M.M. (2001). Inflammatory pain: kinins and antagonists. Curr. Opin. Anaesthesiol., 14, 519-526.
20. CAMPOS, M.M., CABRINI, D.A., CARDOZO, A.H., RAE, G.A., TORO, J.H. & CALIXTO, J.B. (2001). Changes in paw oedema triggered via bradykinin B(1) and B(2) receptors in streptozotocin-diabetic rats. Eur. J. Pharmacol., 416, 169-177.
21. 2 receptors in bradykinin-induced rat paw oedema. Br. J. Pharmacol., 114, 1005-1013.
22. 1 kinin receptors mediating paw edema and formalin-induced nociception. Modulation by glucocorticoids. Can. J. Physiol. Pharmacol., 73, 812-819.
23. 9-BK-induced rat paw oedema by systemic treatment with bacterial endotoxin. Br. J. Pharmacol., 117, 793-798.
24. 2 receptors-mediated rat paw edema by IL-1beta and TNFalpha. Peptides, 19, 1269-1276.
25. 1 kinin-receptor upregulation. Evidence for involvement of protein kinases and nuclear factor kappaB pathways. Br. J. Pharmacol., 127, 1851-1859.
26. 1 receptors in rats. Br. J. Pharmacol., 135, 1107-1114.
27. CAYLA, C., MERINO, V.F., CABRINI, D.A., SILVA JR, J.A., PESQUERO, J.B. & BADER, M. (2002). Structure of the mammalian kinin receptor gene locus. Int. Immunopharmacol., 2, 1721-1727.
28. 1. Genomics, 31, 51-57.
29. CHICHORRO, J.G., LORENZETTI, B.B. & ZAMPRONIO, A.R. (2004). Involvement of bradykinin, cytokines, sympathetic amines and prostaglandins in formalin-induced orofacial nociception in rats. Br. J. Pharmacol., 141, 1175-1184.
30. 1 receptors in allergic airway inflammation. J. Immunol., 169, 2054-2060.
31. CLARK, A.R., DEAN, J.L. & SAKLATVALA, J. (2003). Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38. FEBS Lett., 546, 37-44.
32. 2 kinin receptors in formalin-induced nociceptive response in the mouse. Br. J. Pharmacol., 110, 193-198.
33. COUTURE, R. & LINDSEY, C.J. (2000). Brain kallikrein-kinin system: from receptors to neuronal pathways and physiological functions. In: Handbook of Chemical Anatomy: Peptide Receptors, ed. QUIRION, R., BJ, A. & H., T. pp. 241-298. The Netherlands: Elsevier.
34. COUTURE, R., HARRISSON, M., VIANNA, R.M. & CLOUTIER, F. (2001). Kinin receptors in pain and inflammation. Eur. J. Pharmacol., 429, 161-176.
35. 1 receptors in vivo in a model of persistent inflammatory mechanical hyperalgesia in the rat. Neuropharmacology, 33, 127-133.
36. 1 bradykinin receptors and sensory neurones. Br. J. Pharmacol., 118, 1469-1476.
37. 1 receptor agonist-induced nociception and oedema formation in the formalin test in mice. Neuropeptides, 32, 393-403.
38. 1 receptor agonist in a non-human primate model: haemodynamic and pro-inflammatory effects. Br. J. Pharmacol., 132, 327-335.
39. DIXON, D.A. (2004). Dysregulated post-transcriptional control of COX-2 gene expression in cancer. Curr. Pharm. Des., 10, 635-646.
40. DIXON, D.A., KAPLAN, C.D., MCINTYRE, T.M., ZIMMERMAN, O.A. & PRESCOTT, S.M. (2000). Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3′-untranslated region. J. Biol. Chem., 275, 11750-11757.
41. DOBROVOLSKAIA, M.A. & VOGEL, S.N. (2002). Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes Infect., 4, 903-914.
42. DONALDSON, L.F., HANLEY, M.R. & VILLABRANCA, A.C. (1997). Inducible receptors. Trends Pharmacol. Sci., 18, 171-181.
43. 1 receptors for kinins. J. Pharmacol. Exp. Ther., 259, 997-1003.
44. DRAY, A., PATEL, I.A., PERKINS, M.N. & RUEFF, A. (1992). Bradykinin-induced activation of nociceptors: receptor and mechanistic studies on the neonatal rat spinal cord-tail preparation in vitro. Br. J. Pharmacol., 107, 1129-1134.
45. DRAY, A. & PERKINS, M. (1997). Kinins and pain. In: The Handbook of Immunopharmacology: the Kinin System, ed. Farmer, S.G. pp 157-172. London: Academic Press.
46. DUNN, P.M. & RANG, H.P. (1990). Bradykinin-induced depolarization of primary afferent terminals in the neonatal rat spinal cord in vitro. Br. J. Pharmacol., 100, 656-660.
47. DUNN, C., WILTSHIRE, C., MACLAREN, A. & GILLESPIE, D.A. (2002). Molecular mechanism and biological functions of c-Jun N-terminal kinase signalling via the c-Jun transcription factor. Cell. Signal., 14, 585-593.
48. ECKERT, A., VON BANCHET, G.S., SOPPER, S. & PETERSEN, M. (1999). Spatio-temporal pattern of induction of bradykinin receptors and inflammation in rat dorsal root ganglia after unilateral nerve ligation. Pain, 83, 487-497.
49. 2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. Eur. J. Pharmacol., 475, 129-137.
50. 1 bradykinin receptor depends on interaction between the peptide N-terminal L-lysine and the fourth extracellular domain of the receptor. Mol. Pharmacol., 57, 171-179.
51. 2 kinin receptors to agonist stimulation. Immunopharmacology, 45, 13-20.
52. 1 receptors in the rat paw. Br. J. Pharmacol., 139, 973-981.
53. 2 receptor knockout mice and selective antagonists to characterize the nociceptive responses caused by kinins at the spinal cord. Neuropharmacology, 43, 1188-1197.
54. 2 receptor knockout mice. Neuropharmacology, 41, 1006-1012.
55. 2 kinin receptor activation in mice. Br. J. Pharmacol., 141, 787-794.
56. 1 bradykinin receptors in inflammatory mechanical hyperalgesia. Pain, 104, 683-691.
57. 1 receptors in diabetes-induced hyperalgesia in streptozotocin-treated mice. Eur. J. Pharmacol., 457, 115-124.
58. 1 receptor antagonists inhibit diabetes-induced hyperalgesia in mice. Neuropeptides, 37, 36-44.
59. 1 receptor antagonists, R-715 and R-954, in attenuating streptozotocin-diabetic thermal hyperalgesia in mice. Peptides, 24, 1131-1139.
60. GANJU, P., DAVIS, A., PATEL, S., NUNEZ, X. & FOX, A. (2001). p38 stress-activated protein kinase inhibitor reverses bradykinin B(1) receptor-mediated component of inflammatory hyperalgesia. Eur. J. Pharmacol., 421, 191-199.
61. GARCIA LEME, J., HAMAMURA, L., MIGLIORINI, R.H. & LEITE, M.P. (1973). Experimental diabetes and inflammatory reactions in the rat. Agents Actions, 3, 380-381.
62. GIMPL, G., WALZ, W., OHLEMEYER, C. & KETTENMANN, H. (1992). Bradykinin receptors in cultures astrocytes from neonatal brain are linked to physiological responses. Neurosci. Lett., 144, 139-142.
63. 1 receptor-related peptides. Antagonists Hypertension, 28, 833-839.
64. 1 receptors. Can. J. Physiol. Pharmacol, 75, 591-595.
65. 1 receptor: Biochemical and pharmacological characterization. J. Pharmacol. Exp. Ther., 309, 661-669.
66. 2 receptor gene expression in human lung fibroblasts by tumor necrosis factor-alpha: modulation by dexamethasone. Mol. Pharmacol., 57, 1123-1131.
67. 1 in the plasma extravasation of carragenin-induced pleurisy. Life Sci., 70, 937-949.
68. HAYASHI, R., YAMASHITA, N., MATSUI, S., MARUYAMA, M., SUGIYAMA, E. & SUGIYAMA, S. (1998). Bradykinin stimulates interleukin-8 production by human lung fibroblasts. Immunology, 95, 507-511.
69. HEBLICH, F., ENGLAND, S. & DOCHERTY, R.J. (2001). Indirect actions of bradykinin on neonatal rat dorsal root ganglion neurones: a role for non-neuronal cells as nociceptors. J. Physiol., 536, 111-121.
70. 2 bradykinin receptors. Biol. Chem., 382, 123-129.
71. 1 receptor. Int. Immunophannacol., 2, 1747-1754.
72. HOHMEIER, H.E., TRAN, V.V., CHEN, G., GASA, R. & NEWGARD, C.B. (2003). Inflammatory mechanisms in diabetes; lessons form the beta-cell. Int. J. Obes. Relat. Metab. Disord., 21, S12-S16.
73. 2 receptors in allergen-induced bronchial hyperresponsiveness. Am. J. Respir. Crit. Care Med., 160, 1717-1723.
74. HUNT, S.P. & MANTYH, P.W. (2001). The molecular dynamics of pain control. Nat. Rev. Neurosci., 2, 83-91.
75. HUNTER, T. (1995). Protein kinases and phosphatases: the Yin and Yang of protein phosphorylation and signaling. Cell, 80, 225-236.
76. ISHIHARA, K., HAYASH, I., YAMASHINA, S. & MAJIMA, M. (2001). A potential role of bradykinin in angiogenesis and growth of S-180 mouse tumors. Jpn. J. Pharmacol., 87, 318-326.
77. ISHIHARA, K., KAMATA, M., HAYASHI, I., YAMASHINA, S. & MAJIMA, M. (2002). Roles of bradykinin in vascular permeability and angiogenesis in solid tumor. Int. Immunopharmacol., 2, 499-509.
78. JONES, W.K., BROWN, M., REN, X., HE, S. & MCGUINNESS, M. (2003). NF-kappaB as an integrator of diverse signaling pathways: the heart of myocardial signaling? Cardiovasc. Toxicol., 3, 229-254.
79. JULIUS, D. & BASBAUM, A.I. (2001). Molecular mechanisms of nociception. Nature, 413, 203-210.
80. KHASAR, S.G., MIAO, F.J. & LEVINE, J.D. (1995). Inflammation modulates the contribution of receptor-subtypes to bradykinin-induced hyperalgesia in the rat. Neuroscience, 69, 685-690.
81. 1 receptors in ischaemia-induced pancreatitis: functional importance and cellular localisation. Biol. Chem., 384, 1311-1319.
82. 1 receptors in myocardial ischemia: evidence from pharmacological blockade and gene knockout mice. Int. Immunopharmacol., 2, 815-822.
83. 2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages. Mol. Pharmacol., 64, 308-315.
84. LANDGRAF, R.G., JANCAR, S., STEIL, A.A. & SIROIS, P. (2004). Modulation of allergic and immune complex-induced lung inflammation by bradykinin receptor antagonists. Inflamm. Res., 53, 78-83.
85. 2 selective receptor antagonists. Eur. J. Pharmacol., 460, 75-83.
86. 1 receptors induced by tissue injury. J. Immunol., 160, 1419-1426.
87. 1 receptor. Br. J. Pharmacol., 131, 885-892.
88. LASA, M., BROOK, M., SAKLATVALA, J. & CLARK, A.R. (2001). Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38. Mol. Cell. Biol., 21, 771-780.
89. LAVICH, T.R., CORDEIRO, R.S., CALIXTO, J.B., SILVA, P.M. & MARTINS, M.A. (2003). Combined action of vasoactive amines and bradykinin mediates allergen-evoked thermal hyperalgesia in rats. Eur. J. Pharmacol., 462, 185-192.
90. 1 bradykinin receptors and antinociceptive effects of their antagonists in an animal model of neuropathic pain. Pain, 86, 265-271.
91. LEWIS, O.P. (1964). Plasma kinins and inflammation. Metabolism, 13, 1256-1263.
92. LIEN, Y.H., LAI, L.W. & SILVA, A.L. (2003). Pathogenesis of renal ischemia/reperfusion injury: lessons from knockout mice. Life Sci., 74, 543-552.
93. 1 receptors on primary sensory neurones that give rise to small calibre sciatic nerve fibres in rats. Neuroscience, 107, 665-673.
94. MA, Q.-P. & HEAVENS, R. (2001). Basal expression of bradykinin B(1) receptor in the spinal cord in humans and rats. NeuroReport, 12, 2311-2314.
95. 1 receptor in peripheral sensory ganglia in the rat. NeuroReport, 11, 4003-4005.
96. 1 receptor. Biochim. Biophys. Acta., 1264, 223-228.
97. MAHABEER, R. & BHOOLA, K.D. (2000). Kallikrein and kinin receptor genes. Pharmacol. Ther., 88, 77-89.
98. 1 receptors: a review, Immunopharmacology, 30, 1-26.
99. 1 receptors for kinins. Pharmacol. Rev., 50, 357-386.
100. MARCEAU, F., SABOURIN, T., HOULE, S., FORTIN, J.P., PETITCLERC, E., MOLINARO, G. & ADAM, A. (2002). Kinin receptors: functional aspects. Int. Immunopharmacol., 2, 1729-1739.
101. 1 receptor antagonist B9858 inhibits a nociceptive spinal reflex in rabbits. Can. J. Physiol. Pharmacol., 80, 264-268.
102. 1-receptors are induced by myocardial ischaemia-reperfusion in the rabbit. J. Physiol., 530, 69-78.
103. 2 bradykinin receptor. Proc. Natl. Acad. Sci. U.S.A., 88, 7724-7728.
104. 9-bradykinin-induced coronary vasodilation. Br. J. Pharmacol., 128, 275-282.
105. 1 receptors in models of neuropathic and inflammatory pain in the rat. Br. J. Pharmacol., 134, p158.
106. 1 receptor mediated contraction of the rabbit aorta. Regul. Pept., 97, 121-130.
107. 1 receptor expression induced by tissue damage in the rat portal vein. A critical role for mitogen-activated protein kinase and nuclear factor-κB signaling pathways. Circ. Res., 94, 1375-1382.
108. 1 bradykinin receptor. J. Biol. Chem., 269, 21583-21586.
109. MODÉER, T., ANDUREN, I. & YUCEL-LINDBERG, T. (1998). Bradykinin synergistically stimulates interleukin 6 production in human gingival fibroblasts challenged with interleukin 1 or tumour necrosis factor alpha. Cytokine, 10, 26-31.
110. 1 receptor antagonists with multi-enzymatic resistance properties. Can. J. Physiol. Pharmacol., 80, 287-292.
111. NEWTON, R., EDDLESTON, J., HADDAD, E.-B., HAWISA, S., MAK, J., LIM, S., FOX, A.J., DONNELY, L.E. & CHUNG, K.F. (2002). Regulation of kinin receptors in airway epithelial cells by inflammatory cytokines and dexamethasone. Eur. J. Pharmacol., 441, 193-202.
112. 1 receptor. Biochim. Biophys. Acta, 1442, 177-185.
113. 1 receptor gene in inflammation. J. Biol. Chem., 273, 2784-2791.
114. 9-bradykinin and susceptibility to inflammation. J. Biol. Chem., 278, 219-225.
115. NODA, M., KARIURA, Y., AMANO, T., MANAGO, Y., NISHIKAWA, K., AOKI, S. & WADA, K. (2003). Expression and function of bradykinin receptors in microglia. Life Sci., 72, 1573-1581.
116. 2 receptors: normal distribution and alterations induced by epilepsy. J. Comp. Neurol., 461, 506-519.
117. PAN, Z.K., YE, R.D., CHRISTIANSEN, S.C., JAGELS, M.A., BOKOCH, G.M. & ZURAW, B.L. (1998). Role of the Rho GTPase in bradykinin-stimulated nuclear factor-κB activation and IL-1β gene expression in cultured human epithelial cells. J. Immunol., 160, 3038-3045.
118. PANESAR, M.S., GENTRY, C.T., URBAN, L., WALKER, K. & FOX, A. (1998). A model of persistent, inflammation-induced mechanical hyperalgesia in the mouse. Br. J. Pharmacol., 125 (Suppl.), 122.
119. 1 receptor up-regulation after lipopolysaccharide administration: role of proinflammatory cytokines and neutrophil influx. J. Immunol., 172, 1839-1847.
120. 1 receptors 'in vivo' in a model of ultra-violet irradiation-induced thermal hyperalgesia in the rat. Br. J. Pharmacol., 110, 1441-1444.
121. 9- bradykinin-mediated thermal hyperalgesia in the rat. Neuropharmacology, 33, 657-660.
122. 8]-BK and Hoe 140, in two models of persistent hyperalgesia in the rat. Pain, 53, 191-197.
123. 2 receptor mechanisms and cytokine-induced hyperalgesia in the rat. Can. J. Physiol. Pharmacol., 73, 832-836.
124. 1 receptors. Proc. Natl. Acad. Sci. U.S.A., 97, 8140-8145.
125. 1 receptor gene. Biochem. Biophys. Res. Commun., 224, 281.
126. PETERSEN, M., ECKERT, A.S., VON BANCHET, O.S., HEPPELMANN, B., KLUSCH, A. & KNIFFKI, K.D. (1998). Plasticity in the expression of bradykinin binding sites in sensory neurons after mechanical nerve injury. Neuroscience, 83, 949-959.
127. 1 in human lung fibroblasts. Mol. Pharmacol., 56, 325-333.
128. 1 receptor up-regulation by interleukin-1β agonist occurs through independent and synergistic intracellular signaling mechanisms in human lung fibroblasts. J. Pharmacol. Exp. Ther., 298, 77-85.
129. PHAGOO, S.B., YAQOOB, M., HERRERA-MARTINEZ, E., MCINTYRE, P., JONES, C. & BURGESS, G.M. (2000). Regulation of bradykinin receptor gene expression in human lung fibroblasts. Eur. J. Pharmacol., 397, 237-246.
130. 2 receptors, tumour necrosis factor alpha and inflammatory hyperalgesia. Br. J. Pharmacol., 126, 649-656.
131. PREMKUMAR, L.S. & AHERN, O.P. (2000). Induction of vanilloid receptor channel activity by protein kinase C. Nature, 408, 985-990.
132. PROUD, D. & KAPLAN, A.P. (1988). Kinin formation: mechanisms and role in inflammatory disorders. Annu. Rev. Immunol., 6, 49-83.
133. RAIDOO, D.M., SWANT, S., MAHABEER, R. & BHOOLA, K.D. (1999). Kinin receptors are expressed in human astrocytic tumour cells. Immunopharmacology, 43, 255-263.
134. RASHID, M.H., INOUE, M., MATSUMOTO, M. & UEDA, H. (2004). Switching of bradykinin-mediated nociception following partial sciatic nerve injury in mice. J. Pharmacol. Exp. Ther., 308, 1158-1164.
135. REGOLI, D. & BARABE, J. (1980). Pharmacology of bradykinin and related kinins. Pharmacol. Rev., 32, 1-46.
136. REGOLI, D., BARABÉ, J. & PARK, W.K. (1977). Receptors for bradykinin in rabbit aortae. Can. J. Physiol. Pharmacol., 55, 855-867.
137. REGOLI, D., NSA ALLOGHO, S., RIZZI, A. & GOBEIL, F.J. (1998). Bradykinin receptors and their antagonists. Eur. J. Pharmacol., 348, 1-10.
138. REGOLI, D., RIZZI, A., PERRON, S.L. & GOBEIL, F. (2001). Classification of kinin receptors. Biol. Chem., 382, 31-35.
139. 8]BK. Eur. J. Pharmacol., 163, 263-272.
140. 2 receptor on nociception in rats and mice. Pain, 71, 89-97.
141. 1 receptor in fresh or cultured rabbit aortic smooth muscle: role of NF-κB. Am. J. Physiol. Heart. Circ. Physiol., 283, H227-H237.
142. SAINZ, I.M., UKNIS, A.B., ISORDIA-SALAS, I., DELA CADENA, R.A., PIXLEY, R.A. & COLMAN, R.W. (2004). Interactions between bradykinin (BK) and cell adhesion molecule (CAM) expression in peptidoglycan-polysaccharide (PG-PS)-induced arthritis. FASEB J., Published online March, 4, 2004.
143. 1 receptor in isolated human umbilical vein: an experimental model of the in vitro up-regulation. Acta Pharmacol. Sinica, 21, 105-110.
144. 1 receptor-sensitized responses in human umbilical vein. J. Pharmacol. Exp. Ther., 301, 975-980.
145. 1-receptor in cultured human lung fibroblasts. J. Clin. Invest., 101, 2080-2091.
146. SCHARFSTEIN, J., SCHMITZ, V., MORANDI, V., CAPELLA, M.M., LIMA, A.P., MORROT, A., JULIANO, L. & MULLER-ESTERL, W. (2000). Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B2 receptors. J. Exp. Med., 192, 1289-1300.
147. 2 receptor knockout mice. Neuropharmacology, 36, 1009-1017.
148. SEABROOK, G.R., BOWERY, B.J. & HILL, R.G. (1995). Bradykinin receptors in mouse and rat isolated superior cervical ganglia. Br. J. Pharmacol., 115, 368-372.
149. 2 and neurokinin-1 receptor activation on endothelial cell proliferation in acute synovitis. FASEB J., 18, 762-764.
150. SHENKER, N., HAIGH, R., ROBERTS, E., MAPP, P., HARRIS, A. & BLAKE, D. (2001). Pain, neurogenic inflammation and symmetry in medical practice. Pain
151. SHIBATA, M., OHKUBO, T., TAKAHASHI, H. & INOKI, R. (1989). Modified formalin test: characteristic biphasic pain response. Pain, 38, 347-352.
152. 1 bradykinin receptor mRNA in the primate brain and spinal cord: an in situ hybridization study. J. Comp. Neurol., 465, 372-384.
153. SOT, U., MISTEREK, K., GUMULKA, S.W. & DOROCIAK, A. (2002). Intrathecal bradykinin administration: opposite effects on nociceptive transmission. Pharmacology, 66, 76-80.
154. 1 receptors in the local, remote, and systemic inflammatory responses that follow intestinal ischemia and reperfusion injury. J. Immunol., 172, 2542-2548.
155. STEWART, J.M. (2003). Bradykinin antagonists as anti-cancer agents. Curr. Pharm. Design, 9, 2036-2042.
156. STEWART, J.M., GERA, L., HANSON, W., ZUZACK, J.S., BUCKARD, M., MCCULLOUGH, R. & WHALLEY, E.T. (1996). A new generation of bradykinin antagonists. Immunopharmacology, 33, 51-60.
157. STEWART, J.M., GERA, L., YORK, E.J., CHAN, D.C. & BUNN, P. (1999). Bradykinin antagonists: present progress and future prospects. Immunopharmacology, 43, 155-161.
158. 1 receptor antagonist. J. Am. Chem. Soc., 125, 7516-7517.
159. 2 receptor antagonists in rats. Pain, 66, 99-103.
160. TAUB, J.S., GUO, R., LEEB-LUNDBERG, L.M., MADDEN, J.F. & DAAKA, Y. (2003). Bradykinin receptor subtype 1 expression and function in prostate cancer. Cancer Res., 63, 2037-2041.
161. 2) subtypes. FASEB J., 17, 73-75.
162. 1 receptor-mediated contractile response in isolated rat ileum. Biochem. Pharmacol., 63, 2043-2053.
163. 9-BK in mouse pleurisy. Br. J. Pharmacol., 123, 281-291.
164. 1 receptor in the lung of streptozotocin-diabetic rat: autoradiographic and functional evidence. Br. J. Pharmacol., 138, 13-22.
165. WANG, J.W., SU, W., LAW, Y.P., LU, C.H., CHEN, Y.C., WANG, J.L., CHANG, H.J., CHEN, W.C. & JAN, C.R. (2001). Mechanism of bradykinin-induced Ca(2+) mobilization in MG63 human osteosarcoma cells. Harm. Res., 55, 265-270.
166. WATKINS, L.R. & MAIER, S.F. (2003). Glia: a novel drug discovery target for clinical pain. Nat. Rev. Drug Discov., 2, 973-985.
167. 2 bradykinin receptors encoded by distinct mRNAs. J. Neurochem., 62, 1247-1253.
168. 1 receptors in rat tissues. Mediat. Inflamm., 10, 163-167.
169. 1 receptor antagonist. Eur. J. Pharmacol., 205, 217-218.
170. 1 antagonists. J. Med. Chem., 46, 1803-1806.
171. WOOLF, C.J. & MANNION, R.J. (1999). Neuropathic pain: aetiology, Symptoms, mechanisms, and management. Lancet, 353, 1959-1964.
172. 1 receptor is constitutively expressed in the rat sensory nervous system. Neurosci. Lett., 294, 175-178.
173. WU, J., AKAIKE, T., HAYASHIDA, K., MIYAMOTO, Y., NAKAGAWA, T., MIYAKAWA, K., MULLER-ESTERL, W. & MAEDA, H. (2002). Identification of bradykinin receptors in clinical cancer specimens and murine tumor tissues. Int. J. Cancer, 98, 29-35.
174. YAMAGUCHI-SASE, S., HAYASHI, I., OKAMOTO, H., NARA, Y., MATSUZAKI, S., HOKA, S. & MAJIMA, M. (2003). Amelioration of hyperalgesia by kinin receptor antagonists or kininogen deficiency in chronic constriction nerve injury in rats. Inflamm. Res., 52, 164-169.
175. 1 receptor gene and preliminary characterization of its regulatory regions. Biochem. Biophys. Res. Commun., 222, 18-25.
176. YANG, S.H., SHARROCKS, A.D. & WHITMARSH, A.J. (2003). Transcriptional regulation by the MAP-kinase signaling cascades. Gene, 320, 3-21.
177. 1 receptor gene expression. J. Cell. Biochem., 82, 38-45.
178. 1 receptor minigene: participation of c-jun in the process. J. Cell. Biochem., 82, 163-170.
179. ZHANG, Y., ADNER, M. & CARDELL, L.O. (2004). Up-regulation of bradykinin receptors in a murine in-vitro model of chronic airway inflammation. Eur. J. Pharmacol., 489, 117-126.
180. 1 receptor gene expression. Biochem. J., 330, 361-366.
181. 1 receptor messenger RNA: cloning and functional characterization of the 3′-untranslated region. Mol. Cell. Biol. Res. Commun., 1, 29-35.