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Volumn 4, Issue 9, 2015, Pages 1-2

The checkpoint inhibitor TIGIT limits antitumor and antiviral CD8+ T cell responses

Author keywords

Antibodies; Cancer immunotherapy; CD226; PD1; TIGIT; Virus

Indexed keywords

CHECKPOINT KINASE INHIBITOR; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; T LYMPHOCYTE RECEPTOR; TIGIT RECEPTOR; UNCLASSIFIED DRUG;

EID: 84944446213     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2015.1036214     Document Type: Article
Times cited : (41)

References (10)
  • 3
    • 57849101994 scopus 로고    scopus 로고
    • The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
    • PMID:19011627
    • Yu X, Harden K, Gonzalez LC, Francesco M, Chiang E, Irving B, Tom I, Ivelja S, Refino CJ, Clark H et al. The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells. Nat Immunol 2009; 10:48-57; PMID:19011627; http://dx.doi.org/10.1038/ni.1674
    • (2009) Nat Immunol , vol.10 , pp. 48-57
    • Yu, X.1    Harden, K.2    Gonzalez, L.C.3    Francesco, M.4    Chiang, E.5    Irving, B.6    Tom, I.7    Ivelja, S.8    Refino, C.J.9    Clark, H.10
  • 4
    • 84859468877 scopus 로고    scopus 로고
    • Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering
    • PMID:22421438
    • Stengel KF, Harden-Bowles K, Yu X, Rouge L, Yin J, Comps-Agrar L, Wiesmann C, Bazan JF, Eaton DL, Grogan JL. Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering. Proc Natl Acad Sci U S A 2012; 109:5399-404; PMID:22421438; http://dx.doi.org/ 10.1073/pnas.1120606109
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 5399-5404
    • Stengel, K.F.1    Harden-Bowles, K.2    Yu, X.3    Rouge, L.4    Yin, J.5    Comps-Agrar, L.6    Wiesmann, C.7    Bazan, J.F.8    Eaton, D.L.9    Grogan, J.L.10
  • 7
    • 84898681799 scopus 로고    scopus 로고
    • Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses
    • PMID:24745333
    • Joller N, Lozano E, Burkett PR, Patel B, Xiao S, Zhu C, Xia J, Tan TG, Sefik E, Yajnik V et al. Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. Immunity 2014; 40:569-81; PMID:24745333; http:// dx.doi.org/10.1016/j.immuni.2014.02.012
    • (2014) Immunity , vol.40 , pp. 569-581
    • Joller, N.1    Lozano, E.2    Burkett, P.R.3    Patel, B.4    Xiao, S.5    Zhu, C.6    Xia, J.7    Tan, T.G.8    Sefik, E.9    Yajnik, V.10
  • 8
    • 84860329359 scopus 로고    scopus 로고
    • The TIGIT/CD226 axis regulates human T cell function
    • PMID:22427644
    • Lozano E, Dominguez-Villar M, Kuchroo V, Hafler DA. The TIGIT/CD226 axis regulates human T cell function. J Immunol 2012; 188:3869-75; PMID:22427644; http://dx.doi.org/10.4049/jimmunol.1103627
    • (2012) J Immunol , vol.188 , pp. 3869-3875
    • Lozano, E.1    Dominguez-Villar, M.2    Kuchroo, V.3    Hafler, D.A.4
  • 9
    • 84903470168 scopus 로고    scopus 로고
    • T-cell immunoglobulin and ITIM domain (TIGIT) receptor/poliovirus receptor (PVR) ligand engagement suppresses interferon-gamma production of natural killer cells via betaarrestin 2-mediated negative signaling
    • PMID:24817116
    • Li M, Xia P, Du Y, Liu S, Huang G, Chen J, Zhang H, Hou N, Cheng X, Zhou L et al. T-cell immunoglobulin and ITIM domain (TIGIT) receptor/poliovirus receptor (PVR) ligand engagement suppresses interferon-gamma production of natural killer cells via betaarrestin 2-mediated negative signaling. JBiol Chem 2014; 289:17647-57; PMID:24817116; http://dx.doi. org/10.1074/jbc.M114.572420
    • (2014) JBiol Chem , vol.289 , pp. 17647-17657
    • Li, M.1    Xia, P.2    Du, Y.3    Liu, S.4    Huang, G.5    Chen, J.6    Zhang, H.7    Hou, N.8    Cheng, X.9    Zhou, L.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.