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Volumn 309, Issue 8, 2015, Pages R795-R804

PPG neurons of the lower brain stem and their role in brain GLP-1 receptor activation

Author keywords

Appetite; Brain stem; Glucagon like peptide 1; Hippocampus; Neuroanatomy

Indexed keywords

CHOLECYSTOKININ; GHRELIN; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; LEPTIN; NEUROTRANSMITTER; PREPROGLUCAGON; YELLOW FLUORESCENT PROTEIN; PROGLUCAGON;

EID: 84944412987     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00333.2015     Document Type: Review
Times cited : (69)

References (111)
  • 1
    • 69549138878 scopus 로고    scopus 로고
    • Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer’s disease
    • Abbas T, Faivre E, Holscher C. Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer’s disease. Behav Brain Res 205: 265-271, 2009.
    • (2009) Behav Brain Res , vol.205 , pp. 265-271
    • Abbas, T.1    Faivre, E.2    Holscher, C.3
  • 2
    • 71249140739 scopus 로고    scopus 로고
    • Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats
    • Abbott SB, Stornetta RL, Socolovsky CS, West GH, Guyenet PG. Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats. J Physiol 587: 5613-5631, 2009.
    • (2009) J Physiol , vol.587 , pp. 5613-5631
    • Abbott, S.B.1    Stornetta, R.L.2    Socolovsky, C.S.3    West, G.H.4    Guyenet, P.G.5
  • 3
    • 84928009282 scopus 로고    scopus 로고
    • Neuroprotective effects of vildagliptin in rat rotenone Parkinson’s disease model: Role of RAGE-NF-B and Nrf2-antioxidant signaling pathways
    • Abdelsalam RM, Safar MM. Neuroprotective effects of vildagliptin in rat rotenone Parkinson’s disease model: role of RAGE-NF-B and Nrf2-antioxidant signaling pathways. J Neurochem 133: 700-707, 2015.
    • (2015) J Neurochem , vol.133 , pp. 700-707
    • Abdelsalam, R.M.1    Safar, M.M.2
  • 4
    • 84904468017 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor signaling in the lateral parabrachial nucleus contributes to the control of food intake and motivation to feed
    • Alhadeff AL, Baird JP, Swick JC, Hayes MR, Grill HJ. Glucagon-like peptide-1 receptor signaling in the lateral parabrachial nucleus contributes to the control of food intake and motivation to feed. Neuropsychopharmacology 39: 2233-2243, 2014.
    • (2014) Neuropsychopharmacology , vol.39 , pp. 2233-2243
    • Alhadeff, A.L.1    Baird, J.P.2    Swick, J.C.3    Hayes, M.R.4    Grill, H.J.5
  • 5
    • 84856102513 scopus 로고    scopus 로고
    • GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake
    • Alhadeff AL, Rupprecht LE, Hayes MR. GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake. Endocrinology 153: 647-658, 2012.
    • (2012) Endocrinology , vol.153 , pp. 647-658
    • Alhadeff, A.L.1    Rupprecht, L.E.2    Hayes, M.R.3
  • 6
    • 58149484806 scopus 로고    scopus 로고
    • Loss of cholecystokinin and glucagon-like peptide-1-induced satiation in mice lacking serotonin 2C receptors
    • Asarian L. Loss of cholecystokinin and glucagon-like peptide-1-induced satiation in mice lacking serotonin 2C receptors. Am J Physiol Regul Integr Comp Physiol 296: R51-R56, 2009.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.296
    • Asarian, L.1
  • 7
    • 77949837737 scopus 로고    scopus 로고
    • Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist
    • Baraboi ED, Smith P, Ferguson AV, Richard D. Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist. Am J Physiol Regul Integr Comp Physiol 298: R1098-R1110, 2010.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.298
    • Baraboi, E.D.1    Smith, P.2    Ferguson, A.V.3    Richard, D.4
  • 8
    • 79952394105 scopus 로고    scopus 로고
    • Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide-1 loss of function
    • Barrera JG, Jones KR, Herman JP, D’Alessio DA, Woods SC, Seeley RJ. Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide-1 loss of function. J Neurosci 31: 3904-3913, 2011.
    • (2011) J Neurosci , vol.31 , pp. 3904-3913
    • Barrera, J.G.1    Jones, K.R.2    Herman, J.P.3    D’Alessio, D.A.4    Woods, S.C.5    Seeley, R.J.6
  • 11
    • 84942198303 scopus 로고    scopus 로고
    • Distribution and characterisation of glucagon-like peptide-1 receptor expressing cells in the mouse brain
    • Cork SC, Richards JE, Holt MK, Gribble FM, Reimann F, Trapp S. Distribution and characterisation of glucagon-like peptide-1 receptor expressing cells in the mouse brain. Mol Metab DOI:10.1016/j.molmet.2015.07.008, 2015.
    • (2015) Mol Metab
    • Cork, S.C.1    Richards, J.E.2    Holt, M.K.3    Gribble, F.M.4    Reimann, F.5    Trapp, S.6
  • 12
    • 84873395982 scopus 로고    scopus 로고
    • Alzheimer’s disease and insulin resistance: translating basic science into clinical applications
    • De Felice FG. Alzheimer’s disease and insulin resistance: translating basic science into clinical applications. J Clin Invest 123: 531-539, 2013.
    • (2013) J Clin Invest , vol.123 , pp. 531-539
    • De Felice, F.G.1
  • 13
    • 84859360922 scopus 로고    scopus 로고
    • The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: A new role for mesolimbic GLP-1 receptors
    • Dickson SL, Shirazi RH, Hansson C, Bergquist F, Nissbrandt H, Skibicka KP. The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1 receptors. J Neurosci 32: 4812-4820, 2012.
    • (2012) J Neurosci , vol.32 , pp. 4812-4820
    • Dickson, S.L.1    Shirazi, R.H.2    Hansson, C.3    Bergquist, F.4    Nissbrandt, H.5    Skibicka, K.P.6
  • 14
    • 85018169564 scopus 로고    scopus 로고
    • Preliminary examination of glucagon-like peptide-1 levels in women with purging disorder and bulimia nervosa
    • Dossat AM, Bodell LP, Williams DL, Eckel LA, Keel PK. Preliminary examination of glucagon-like peptide-1 levels in women with purging disorder and bulimia nervosa. Int J Eat Dis 2014.
    • (2014) Int J Eat Dis
    • Dossat, A.M.1    Bodell, L.P.2    Williams, D.L.3    Eckel, L.A.4    Keel, P.K.5
  • 16
    • 80054035293 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake
    • Dossat AM, Lilly N, Kay K, Williams DL. Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake. J Neurosci 31: 14453-14457, 2011.
    • (2011) J Neurosci , vol.31 , pp. 14453-14457
    • Dossat, A.M.1    Lilly, N.2    Kay, K.3    Williams, D.L.4
  • 17
    • 84884583757 scopus 로고    scopus 로고
    • Incretin action in the pancreas: Potential promise, possible perils, and pathological pitfalls
    • Drucker DJ. Incretin action in the pancreas: potential promise, possible perils, and pathological pitfalls. Diabetes 62: 3316-3323, 2013.
    • (2013) Diabetes , vol.62 , pp. 3316-3323
    • Drucker, D.J.1
  • 19
    • 84880459479 scopus 로고    scopus 로고
    • The glucagon-like peptide 1 analogue, exendin-4, attenuates the rewarding properties of psychostimulant drugs in mice
    • Egecioglu E, Engel JA, Jerlhag E. The glucagon-like peptide 1 analogue, exendin-4, attenuates the rewarding properties of psychostimulant drugs in mice. PLoS One 8: e69010, 2013.
    • (2013) Plos One , vol.8
    • Egecioglu, E.1    Engel, J.A.2    Jerlhag, E.3
  • 22
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    • Flint A, Raben A, Astrup A, Holst JJ. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 101: 515-520, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Holst, J.J.4
  • 23
    • 44149122563 scopus 로고    scopus 로고
    • GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
    • Gault VA, Holscher C. GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid. Eur J Pharmacol 587: 112-117, 2008.
    • (2008) Eur J Pharmacol , vol.587 , pp. 112-117
    • Gault, V.A.1    Holscher, C.2
  • 24
    • 0345305844 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons
    • Gilman CP, Perry T, Furukawa K, Grieg NH, Egan JM, Mattson MP. Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons. J Neurochem 87: 1137-1144, 2003.
    • (2003) J Neurochem , vol.87 , pp. 1137-1144
    • Gilman, C.P.1    Perry, T.2    Furukawa, K.3    Grieg, N.H.4    Egan, J.M.5    Mattson, M.P.6
  • 31
    • 84936990507 scopus 로고    scopus 로고
    • The GLP-1 receptor agonist liraglutide improves memory function and increases hippocampal CA1 neuronal numbers in a senescence-accelerated mouse model of Alzheimer’s disease
    • Hansen HH, Fabricius K, Barkholt P, Niehoff ML, Morley JE, Jelsing J, Pyke C, Bjerre Knudsen L, Farr SA, Vrang N. The GLP-1 receptor agonist liraglutide improves memory function and increases hippocampal CA1 neuronal numbers in a senescence-accelerated mouse model of Alzheimer’s disease. J Alzheimer’s Dis 46: 877-888, 2015.
    • (2015) J Alzheimer’s Dis , vol.46 , pp. 877-888
    • Hansen, H.H.1    Fabricius, K.2    Barkholt, P.3    Niehoff, M.L.4    Morley, J.E.5    Jelsing, J.6    Pyke, C.7    Bjerre Knudsen, L.8    Farr, S.A.9    Vrang, N.10
  • 32
    • 66649088029 scopus 로고    scopus 로고
    • Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling
    • Hayes MR, Bradley L, Grill HJ. Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling. Endocrinology 150: 2654-2659, 2009.
    • (2009) Endocrinology , vol.150 , pp. 2654-2659
    • Hayes, M.R.1    Bradley, L.2    Grill, H.J.3
  • 34
    • 47949104953 scopus 로고    scopus 로고
    • Caudal brainstem processing is sufficient for behavioral, sympathetic, and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation
    • Hayes MR, Skibicka KP, Grill HJ. Caudal brainstem processing is sufficient for behavioral, sympathetic, and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation. Endocrinology 149: 4059-4068, 2008.
    • (2008) Endocrinology , vol.149 , pp. 4059-4068
    • Hayes, M.R.1    Skibicka, K.P.2    Grill, H.J.3
  • 35
    • 84919725884 scopus 로고    scopus 로고
    • Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain
    • Heppner KM, Kirigiti M, Secher A, Paulsen SJ, Buckingham R, Pyke C, Knudsen LB, Vrang N, Grove KL. Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain. Endocrinology 156: 255-267, 2015.
    • (2015) Endocrinology , vol.156 , pp. 255-267
    • Heppner, K.M.1    Kirigiti, M.2    Secher, A.3    Paulsen, S.J.4    Buckingham, R.5    Pyke, C.6    Knudsen, L.B.7    Vrang, N.8    Grove, K.L.9
  • 36
    • 80755168940 scopus 로고    scopus 로고
    • CCK stimulation of GLP-1 neurons involves 1-adrenoceptor-mediated increase in glutamatergic synaptic inputs
    • Hisadome K, Reimann F, Gribble FM, Trapp S. CCK stimulation of GLP-1 neurons involves 1-adrenoceptor-mediated increase in glutamatergic synaptic inputs. Diabetes 60: 2701-2709, 2011.
    • (2011) Diabetes , vol.60 , pp. 2701-2709
    • Hisadome, K.1    Reimann, F.2    Gribble, F.M.3    Trapp, S.4
  • 37
    • 77955369748 scopus 로고    scopus 로고
    • Leptin directly depolarizes preproglucagon neurons in the nucleus tractus solitarius: Electrical properties of glucagon-like peptide 1 neurons
    • Hisadome K, Reimann F, Gribble FM, Trapp S. Leptin directly depolarizes preproglucagon neurons in the nucleus tractus solitarius: electrical properties of glucagon-like peptide 1 neurons. Diabetes 59: 1890-1898, 2010.
    • (2010) Diabetes , vol.59 , pp. 1890-1898
    • Hisadome, K.1    Reimann, F.2    Gribble, F.M.3    Trapp, S.4
  • 38
    • 70350426017 scopus 로고    scopus 로고
    • Vagally mediated effects of glucagon-like peptide 1: In vitro and in vivo gastric actions
    • Holmes GM, Browning KN, Tong M, Qualls-Creekmore E, Travagli RA. Vagally mediated effects of glucagon-like peptide 1: in vitro and in vivo gastric actions. J Physiol 587: 4749-4759, 2009.
    • (2009) J Physiol , vol.587 , pp. 4749-4759
    • Holmes, G.M.1    Browning, K.N.2    Tong, M.3    Qualls-Creekmore, E.4    Travagli, R.A.5
  • 39
    • 84922053747 scopus 로고    scopus 로고
    • Hippocampal GLP-1 receptors influence food intake, meal size, and effort-based responding for food through volume transmission
    • Hsu TM, Hahn JD, Konanur VR, Lam A, Kanoski SE. Hippocampal GLP-1 receptors influence food intake, meal size, and effort-based responding for food through volume transmission. Neuropsychopharmacology 40: 327-337, 2015.
    • (2015) Neuropsychopharmacology , vol.40 , pp. 327-337
    • Hsu, T.M.1    Hahn, J.D.2    Konanur, V.R.3    Lam, A.4    Kanoski, S.E.5
  • 40
    • 38549123536 scopus 로고    scopus 로고
    • Divergent leptin signaling in proglucagon neurons of the nucleus of the solitary tract in mice and rats
    • Huo L, Gamber KM, Grill HJ, Bjorbaek C. Divergent leptin signaling in proglucagon neurons of the nucleus of the solitary tract in mice and rats. Endocrinology 149: 492-497, 2008.
    • (2008) Endocrinology , vol.149 , pp. 492-497
    • Huo, L.1    Gamber, K.M.2    Grill, H.J.3    Bjorbaek, C.4
  • 41
    • 0023950336 scopus 로고
    • Distribution of glucagonlike peptide I (GLP-I), glucagon, and glicentin in the rat brain: An immunocytochemical study
    • Jin SL, Han VK, Simmons JG, Towle AC, Lauder JM, Lund PK. Distribution of glucagonlike peptide I (GLP-I), glucagon, and glicentin in the rat brain: an immunocytochemical study. J Comp Neurol 271: 519-532, 1988.
    • (1988) J Comp Neurol , vol.271 , pp. 519-532
    • Jin, S.L.1    Han, V.K.2    Simmons, J.G.3    Towle, A.C.4    Lauder, J.M.5    Lund, P.K.6
  • 43
    • 84857045922 scopus 로고    scopus 로고
    • The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide
    • Kanoski SE, Rupprecht LE, Fortin SM, De Jonghe BC, Hayes MR. The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide. Neuropharmacology 62: 1916-1927, 2012.
    • (2012) Neuropharmacology , vol.62 , pp. 1916-1927
    • Kanoski, S.E.1    Rupprecht, L.E.2    Fortin, S.M.3    De Jonghe, B.C.4    Hayes, M.R.5
  • 44
    • 0036198285 scopus 로고    scopus 로고
    • Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier
    • Kastin AJ, Akerstrom V, Pan W. Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier. J Mol Neurosci 18: 7-14, 2002.
    • (2002) J Mol Neurosci , vol.18 , pp. 7-14
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 45
    • 0036896243 scopus 로고    scopus 로고
    • The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness
    • Kinzig KP, D’Alessio DA, Seeley RJ. The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. J Neurosci 22: 10470-10476, 2002.
    • (2002) J Neurosci , vol.22 , pp. 10470-10476
    • Kinzig, K.P.1    D’Alessio, D.A.2    Seeley, R.J.3
  • 48
    • 71549115201 scopus 로고    scopus 로고
    • Serotonin 2C receptor signaling in a diffuse neuronal network is necessary for LPS anorexia
    • Kopf BS, Langhans W, Geary N, Asarian L. Serotonin 2C receptor signaling in a diffuse neuronal network is necessary for LPS anorexia. Brain Res 1306: 77-84, 2010.
    • (2010) Brain Res , vol.1306 , pp. 77-84
    • Kopf, B.S.1    Langhans, W.2    Geary, N.3    Asarian, L.4
  • 49
    • 84920059626 scopus 로고    scopus 로고
    • GLP-1 and exendin-4 transiently enhance GABAA receptor-mediated synaptic and tonic currents in rat hippocampal CA3 pyramidal neurons
    • Korol SV, Jin Z, Babateen O, Birnir B. GLP-1 and exendin-4 transiently enhance GABAA receptor-mediated synaptic and tonic currents in rat hippocampal CA3 pyramidal neurons. Diabetes 64: 79-89, 2015.
    • (2015) Diabetes , vol.64 , pp. 79-89
    • Korol, S.V.1    Jin, Z.2    Babateen, O.3    Birnir, B.4
  • 50
    • 84916931217 scopus 로고    scopus 로고
    • Differential activation of chemically identified neurons in the caudal nucleus of the solitary tract in non-entrained rats after intake of satiating vs. Non-satiating meals
    • Kreisler AD, Davis EA, Rinaman L. Differential activation of chemically identified neurons in the caudal nucleus of the solitary tract in non-entrained rats after intake of satiating vs. non-satiating meals. Physiol Behav 136: 47-54, 2014.
    • (2014) Physiol Behav , vol.136 , pp. 47-54
    • Kreisler, A.D.1    Davis, E.A.2    Rinaman, L.3
  • 52
    • 34447512947 scopus 로고    scopus 로고
    • Signals generating anorexia during acute illness
    • Langhans W. Signals generating anorexia during acute illness. Proc Nutr Soc 66: 321-330, 2007.
    • (2007) Proc Nutr Soc , vol.66 , pp. 321-330
    • Langhans, W.1
  • 53
    • 0031029936 scopus 로고    scopus 로고
    • Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem
    • Larsen PJ, Tang-Christensen M, Holst JJ, Orskov C. Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem. Neuroscience 77: 257-270, 1997.
    • (1997) Neuroscience , vol.77 , pp. 257-270
    • Larsen, P.J.1    Tang-Christensen, M.2    Holst, J.J.3    Orskov, C.4
  • 54
    • 84907190290 scopus 로고    scopus 로고
    • Lixisenatide improves recognition memory and exerts neuroprotective actions in high-fat fed mice
    • Lennox R, Flatt PR, Gault VA. Lixisenatide improves recognition memory and exerts neuroprotective actions in high-fat fed mice. Peptides 61: 38-47, 2014.
    • (2014) Peptides , vol.61 , pp. 38-47
    • Lennox, R.1    Flatt, P.R.2    Gault, V.A.3
  • 55
    • 84936871959 scopus 로고    scopus 로고
    • Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease
    • Liu W, Jalewa J, Sharma M, Li G, Li L, Holscher C. Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease. Neuroscience 303: 42-50, 2015.
    • (2015) Neuroscience , vol.303 , pp. 42-50
    • Liu, W.1    Jalewa, J.2    Sharma, M.3    Li, G.4    Li, L.5    Holscher, C.6
  • 56
    • 84871928077 scopus 로고    scopus 로고
    • Preproglucagon (PPG) neurons innervate neurochemically identified autonomic neurons in the mouse brainstem
    • Llewellyn-Smith IJ, Gnanamanickam GJ, Reimann F, Gribble FM, Trapp S. Preproglucagon (PPG) neurons innervate neurochemically identified autonomic neurons in the mouse brainstem. Neuroscience 229: 130-143, 2013.
    • (2013) Neuroscience , vol.229 , pp. 130-143
    • Llewellyn-Smith, I.J.1    Gnanamanickam, G.J.2    Reimann, F.3    Gribble, F.M.4    Trapp, S.5
  • 57
    • 84911897652 scopus 로고    scopus 로고
    • Spinally projecting preproglucagon axons preferentially innervate sympathetic preganglionic neurons
    • Llewellyn-Smith IJ, Marina N, Manton RN, Reimann F, Gribble FM, Trapp S. Spinally projecting preproglucagon axons preferentially innervate sympathetic preganglionic neurons. Neuroscience 284: 872-887, 2015.
    • (2015) Neuroscience , vol.284 , pp. 872-887
    • Llewellyn-Smith, I.J.1    Marina, N.2    Manton, R.N.3    Reimann, F.4    Gribble, F.M.5    Trapp, S.6
  • 58
    • 79953189360 scopus 로고    scopus 로고
    • Preproglucagon neurons project widely to autonomic control areas in the mouse brain
    • Llewellyn-Smith IJ, Reimann F, Gribble FM, Trapp S. Preproglucagon neurons project widely to autonomic control areas in the mouse brain. Neuroscience 180: 111-121, 2011.
    • (2011) Neuroscience , vol.180 , pp. 111-121
    • Llewellyn-Smith, I.J.1    Reimann, F.2    Gribble, F.M.3    Trapp, S.4
  • 59
    • 84889094495 scopus 로고    scopus 로고
    • The hormonal signature of energy deficit: Increasing the value of food reward
    • Lockie SH, Andrews ZB. The hormonal signature of energy deficit: Increasing the value of food reward. Mol Metab 2: 329-336, 2013.
    • (2013) Mol Metab , vol.2 , pp. 329-336
    • Lockie, S.H.1    Rews, Z.B.2
  • 61
    • 84900531001 scopus 로고    scopus 로고
    • Systemic leptin dose-dependently increases STAT3 phosphorylation within hypothalamic and hindbrain nuclei
    • Maniscalco JW, Rinaman L. Systemic leptin dose-dependently increases STAT3 phosphorylation within hypothalamic and hindbrain nuclei. Am J Physiol Regul Integr Comp Physiol 306: R576-R585, 2014.
    • (2014) Am J Physiol Regul Integr Comp Physiol , vol.306
    • Maniscalco, J.W.1    Rinaman, L.2
  • 62
    • 84920949773 scopus 로고    scopus 로고
    • GLP-1: A mediator of the beneficial metabolic effects of bariatric surgery?
    • Manning S, Pucci A, Batterham RL. GLP-1: a mediator of the beneficial metabolic effects of bariatric surgery? Physiology (Bethesda) 30: 50-62, 2015.
    • (2015) Physiology (Bethesda) , vol.30 , pp. 50-62
    • Manning, S.1    Pucci, A.2    Batterham, R.L.3
  • 63
    • 77956843436 scopus 로고    scopus 로고
    • Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration
    • Marina N, Abdala AP, Trapp S, Li A, Nattie EE, Hewinson J, Smith JC, Paton JF, Gourine AV. Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration. J Neurosci 30: 12466-12473, 2010.
    • (2010) J Neurosci , vol.30 , pp. 12466-12473
    • Marina, N.1    Abdala, A.P.2    Trapp, S.3    Li, A.4    Nattie, E.E.5    Hewinson, J.6    Smith, J.C.7    Paton, J.F.8    Gourine, A.V.9
  • 64
    • 0031891391 scopus 로고    scopus 로고
    • PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats
    • McMahon LR, Wellman PJ. PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats. Am J Physiol Regul Integr Comp Physiol 274: R23-R29, 1998.
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.274
    • McMahon, L.R.1    Wellman, P.J.2
  • 65
    • 0033545166 scopus 로고    scopus 로고
    • Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system
    • Merchenthaler I, Lane M, Shughrue P. Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system. J Comp Neurol 403: 261-280, 1999.
    • (1999) J Comp Neurol , vol.403 , pp. 261-280
    • Merchenthaler, I.1    Lane, M.2    Shughrue, P.3
  • 68
    • 0026321360 scopus 로고
    • Widespread release of peptides in the central nervous system: Quantitation of tannic acid-captured exocytoses
    • Morris JF, Pow DV. Widespread release of peptides in the central nervous system: quantitation of tannic acid-captured exocytoses. Anat Record 231: 437-445, 1991.
    • (1991) Anat Record , vol.231 , pp. 437-445
    • Morris, J.F.1    Pow, D.V.2
  • 69
    • 84889571471 scopus 로고    scopus 로고
    • Alzheimer’s disease neuroimaging I. Impaired glycemia increases disease progression in mild cognitive impairment
    • Morris JK, Vidoni ED, Honea RA, Burns JM Alzheimer’s disease neuroimaging I. Impaired glycemia increases disease progression in mild cognitive impairment. Neurobiol Aging 35: 585-589, 2014.
    • (2014) Neurobiol Aging , vol.35 , pp. 585-589
    • Morris, J.K.1    Vidoni, E.D.2    Honea, R.A.3    Burns, J.M.4
  • 70
    • 46149086585 scopus 로고    scopus 로고
    • Central control of thermogenesis in mammals
    • Morrison SF, Nakamura K, Madden CJ. Central control of thermogenesis in mammals. Exp Physiol 93: 773-797, 2008.
    • (2008) Exp Physiol , vol.93 , pp. 773-797
    • Morrison, S.F.1    Nakamura, K.2    Madden, C.J.3
  • 71
    • 0033519562 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 modulates neuronal activity in the rat’s hippocampus
    • Oka JI, Goto N, Kameyama T. Glucagon-like peptide-1 modulates neuronal activity in the rat’s hippocampus. Neuroreport 10: 1643-1646, 1999.
    • (1999) Neuroreport , vol.10 , pp. 1643-1646
    • Oka, J.I.1    Goto, N.2    Kameyama, T.3
  • 72
    • 0029903111 scopus 로고    scopus 로고
    • Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
    • Orskov C, Poulsen SS, Moller M, Holst JJ. Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. Diabetes 45: 832-835, 1996.
    • (1996) Diabetes , vol.45 , pp. 832-835
    • Orskov, C.1    Poulsen, S.S.2    Moller, M.3    Holst, J.J.4
  • 76
    • 84899420832 scopus 로고    scopus 로고
    • Circulating glucagon-like peptide-1 (GLP-1) inhibits eating in male rats by acting in the hindbrain and without inducing avoidance
    • Punjabi M, Arnold M, Ruttimann E, Graber M, Geary N, Pacheco-Lopez G, Langhans W. Circulating glucagon-like peptide-1 (GLP-1) inhibits eating in male rats by acting in the hindbrain and without inducing avoidance. Endocrinology 155: 1690-1699, 2014.
    • (2014) Endocrinology , vol.155 , pp. 1690-1699
    • Punjabi, M.1    Arnold, M.2    Ruttimann, E.3    Graber, M.4    Geary, N.5    Pacheco-Lopez, G.6    Langhans, W.7
  • 77
    • 84925596878 scopus 로고    scopus 로고
    • Activation of the GLP-1 receptors in the nucleus of the solitary tract reduces food reward behavior and targets the mesolimbic system
    • Richard JE, Anderberg RH, Goteson A, Gribble FM, Reimann F, Skibicka KP. Activation of the GLP-1 receptors in the nucleus of the solitary tract reduces food reward behavior and targets the mesolimbic system. PLoS One 10: e0119034, 2015.
    • (2015) Plos One , vol.10
    • Richard, J.E.1    Erberg, R.H.2    Goteson, A.3    Gribble, F.M.4    Reimann, F.5    Skibicka, K.P.6
  • 80
    • 0032830989 scopus 로고    scopus 로고
    • Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus
    • Rinaman L. Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus. Am J Physiol Regul Integr Comp Physiol 277: R582-R590, 1999.
    • (1999) Am J Physiol Regul Integr Comp Physiol , vol.277
    • Rinaman, L.1
  • 82
    • 84928563945 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 interacts with ghrelin and leptin to regulate glucose metabolism and food intake through vagal afferent neuron signaling
    • Ronveaux CC, Tome D, Raybould HE. Glucagon-like peptide 1 interacts with ghrelin and leptin to regulate glucose metabolism and food intake through vagal afferent neuron signaling. J Nutr 145: 672-680, 2015.
    • (2015) J Nutr , vol.145 , pp. 672-680
    • Ronveaux, C.C.1    Tome, D.2    Raybould, H.E.3
  • 83
    • 67649636449 scopus 로고    scopus 로고
    • Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms
    • Ruttimann EB, Arnold M, Hillebrand JJ, Geary N, Langhans W. Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms. Endocrinology 150: 1174-1181, 2009.
    • (2009) Endocrinology , vol.150 , pp. 1174-1181
    • Ruttimann, E.B.1    Arnold, M.2    Hillebrand, J.J.3    Geary, N.4    Langhans, W.5
  • 84
    • 50949094723 scopus 로고    scopus 로고
    • Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake
    • Sandoval DA, Bagnol D, Woods SC, D’Alessio DA, Seeley RJ. Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake. Diabetes 57: 2046-2054, 2008.
    • (2008) Diabetes , vol.57 , pp. 2046-2054
    • Sandoval, D.A.1    Bagnol, D.2    Woods, S.C.3    D’Alessio, D.A.4    Seeley, R.J.5
  • 85
    • 84926648779 scopus 로고    scopus 로고
    • Physiology of proglucagon peptides: Role of glucagon and GLP-1 in health and disease
    • Sandoval DA, D’Alessio DA. Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease. Physiol Rev 95: 513-548, 2015.
    • (2015) Physiol Rev , vol.95 , pp. 513-548
    • Sandoval, D.A.1    D’Alessio, D.A.2
  • 87
    • 0023266561 scopus 로고
    • Identification and localization of glucagon-like peptide-1 and its receptor in rat brain
    • Shimizu I, Hirota M, Ohboshi C, Shima K. Identification and localization of glucagon-like peptide-1 and its receptor in rat brain. Endocrinology 121: 1076-1082, 1987.
    • (1987) Endocrinology , vol.121 , pp. 1076-1082
    • Shimizu, I.1    Hirota, M.2    Ohboshi, C.3    Shima, K.4
  • 88
    • 84876179746 scopus 로고    scopus 로고
    • Gut peptide GLP-1 and its analogue, exendin-4, decrease alcohol intake and reward
    • Shirazi RH, Dickson SL, Skibicka KP. Gut peptide GLP-1 and its analogue, exendin-4, decrease alcohol intake and reward. PLoS One 8: e61965, 2013.
    • (2013) Plos One , vol.8
    • Shirazi, R.H.1    Dickson, S.L.2    Skibicka, K.P.3
  • 89
    • 84888777837 scopus 로고    scopus 로고
    • The central GLP-1: Implications for food and drug reward
    • Skibicka KP. The central GLP-1: implications for food and drug reward. Front Neurosci 7: 181, 2013.
    • (2013) Front Neurosci , vol.7 , pp. 181
    • Skibicka, K.P.1
  • 90
    • 84929723419 scopus 로고    scopus 로고
    • Neuroendocrine-autonomic integration in the PVN: Novel roles for dendritically released neuropeptides
    • Stern JE. Neuroendocrine-autonomic integration in the PVN: novel roles for dendritically released neuropeptides. J Neuroendocrinol 27: 487-497, 2015.
    • (2015) J Neuroendocrinol , vol.27 , pp. 487-497
    • Stern, J.E.1
  • 92
    • 56249113754 scopus 로고    scopus 로고
    • Distribution of glucagon-like peptide-1 immunoreactivity in the hypothalamic paraventricular and supraoptic nuclei
    • Tauchi M, Zhang R, D’Alessio DA, Stern JE, Herman JP. Distribution of glucagon-like peptide-1 immunoreactivity in the hypothalamic paraventricular and supraoptic nuclei. J Chem Neuroanat 36: 144-149, 2008.
    • (2008) J Chem Neuroanat , vol.36 , pp. 144-149
    • Tauchi, M.1    Zhang, R.2    D’Alessio, D.A.3    Stern, J.E.4    Herman, J.P.5
  • 96
    • 84867136812 scopus 로고    scopus 로고
    • Neuropeptide transmission in brain circuits
    • van den Pol AN. Neuropeptide transmission in brain circuits. Neuron 76: 98-115, 2012.
    • (2012) Neuron , vol.76 , pp. 98-115
    • Van Den Pol, A.N.1
  • 97
    • 0032756657 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (7-36) amide: A central regulator of satiety and interoceptive stress
    • van Dijk G, Thiele TE. Glucagon-like peptide-1 (7-36) amide: a central regulator of satiety and interoceptive stress. Neuropeptides 33: 406-414, 1999.
    • (1999) Neuropeptides , vol.33 , pp. 406-414
    • Van Dijk, G.1    Thiele, T.E.2
  • 98
    • 79958267987 scopus 로고    scopus 로고
    • The brainstem preproglucagon system in a nonhuman primate (Macaca mulatta)
    • Vrang N, Grove K. The brainstem preproglucagon system in a nonhuman primate (Macaca mulatta). Brain Res 1397: 28-37, 2011.
    • (2011) Brain Res , vol.1397 , pp. 28-37
    • Vrang, N.1    Grove, K.2
  • 99
    • 34247639607 scopus 로고    scopus 로고
    • Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei
    • Vrang N, Hansen M, Larsen PJ, Tang-Christensen M. Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei. Brain Res 1149: 118-126, 2007.
    • (2007) Brain Res , vol.1149 , pp. 118-126
    • Vrang, N.1    Hansen, M.2    Larsen, P.J.3    Tang-Christensen, M.4
  • 101
    • 34447506584 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 excites pancreas-projecting preganglionic vagal motoneurons
    • Wan S, Coleman FH, Travagli RA. Glucagon-like peptide-1 excites pancreas-projecting preganglionic vagal motoneurons. Am J Physiol Gastrointest Liver Physiol 292: G1474-G1482, 2007.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Wan, S.1    Coleman, F.H.2    Travagli, R.A.3
  • 102
    • 63849248275 scopus 로고    scopus 로고
    • Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety
    • Williams DL, Baskin DG, Schwartz MW. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology 150: 1680-1687, 2009.
    • (2009) Endocrinology , vol.150 , pp. 1680-1687
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 103
    • 33845518516 scopus 로고    scopus 로고
    • Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation
    • Williams DL, Baskin DG, Schwartz MW. Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation. Diabetes 55: 3387-3393, 2006.
    • (2006) Diabetes , vol.55 , pp. 3387-3393
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 104
    • 84929302567 scopus 로고    scopus 로고
    • Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces Alzheimer diseaseassociated tau hyperphosphorylation in the hippocampus of rats with type 2 diabetes
    • Xu W, Yang Y, Yuan G, Zhu W, Ma D, Hu S. Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces Alzheimer diseaseassociated tau hyperphosphorylation in the hippocampus of rats with type 2 diabetes. J Invest Med 63: 267-272, 2015.
    • (2015) J Invest Med , vol.63 , pp. 267-272
    • Xu, W.1    Yang, Y.2    Yuan, G.3    Zhu, W.4    Ma, D.5    Hu, S.6
  • 105
    • 0345726358 scopus 로고    scopus 로고
    • Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites
    • Yamamoto H, Kishi T, Lee CE, Choi BJ, Fang H, Hollenberg AN, Drucker DJ, Elmquist JK. Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites. J Neurosci 23: 2939-2946, 2003.
    • (2003) J Neurosci , vol.23 , pp. 2939-2946
    • Yamamoto, H.1    Kishi, T.2    Lee, C.E.3    Choi, B.J.4    Fang, H.5    Hollenberg, A.N.6    Drucker, D.J.7    Elmquist, J.K.8
  • 107
    • 84923216760 scopus 로고    scopus 로고
    • Glucagonlike peptide-1 protects the murine hippocampus against stressors via Akt and ERK1/2 signaling
    • Yoshino Y, Ishisaka M, Tsujii S, Shimazawa M, Hara H. Glucagonlike peptide-1 protects the murine hippocampus against stressors via Akt and ERK1/2 signaling. Biochem Biophys Res Commun 458: 274-279, 2015.
    • (2015) Biochem Biophys Res Commun , vol.458 , pp. 274-279
    • Yoshino, Y.1    Ishisaka, M.2    Tsujii, S.3    Shimazawa, M.4    Hara, H.5
  • 108
    • 84855314566 scopus 로고    scopus 로고
    • Circulating GLP-1 and CCK-8 reduce food intake by capsaicin-insensitive, nonvagal mechanisms
    • Zhang J, Ritter RC. Circulating GLP-1 and CCK-8 reduce food intake by capsaicin-insensitive, nonvagal mechanisms. Am J Physiol Regul Integr Comp Physiol 302: R264-R273, 2012.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302
    • Zhang, J.1    Ritter, R.C.2
  • 109
    • 84871005992 scopus 로고    scopus 로고
    • Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive manner
    • Zhao S, Kanoski SE, Yan J, Grill HJ, Hayes MR. Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive manner. Int J Obes (Lond) 36: 1522-1528, 2012.
    • (2012) Int J Obes (Lond) , vol.36 , pp. 1522-1528
    • Zhao, S.1    Kanoski, S.E.2    Yan, J.3    Grill, H.J.4    Hayes, M.R.5
  • 110
    • 84893181672 scopus 로고    scopus 로고
    • Distribution of glucagon-like peptide 1-immunopositive neurons in human caudal medulla
    • Zheng H, Cai L, Rinaman L. Distribution of glucagon-like peptide 1-immunopositive neurons in human caudal medulla. Brain Struct Funct 220: 1213-1219, 2015.
    • (2015) Brain Struct Funct , vol.220 , pp. 1213-1219
    • Zheng, H.1    Cai, L.2    Rinaman, L.3
  • 111
    • 84940579032 scopus 로고    scopus 로고
    • Glutamatergic phenotype of glucagon-like peptide 1 neurons in the caudal nucleus of the solitary tract in rats
    • Zheng H, Stornetta RL, Agassandian K, Rinaman L. Glutamatergic phenotype of glucagon-like peptide 1 neurons in the caudal nucleus of the solitary tract in rats. Brain Struct Funct 220: 3011-3022, 2015.
    • (2015) Brain Struct Funct , vol.220 , pp. 3011-3022
    • Zheng, H.1    Stornetta, R.L.2    Agassandian, K.3    Rinaman, L.4


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