Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

Fibrogenesis and Tissue Repair

Volumn 8, Issue 1, 2015, Pages

  Irvine, Katharine M ^a   Clouston, Andrew D ^a   Gadd, Victoria L ^a   Miller, Gregory C ^a   Wong, Weng Yew ^a   Melino, Michelle ^b   Maradana, Muralidhara Rao ^a   MacDonald, Kelli ^b   Lang, Richard A ^c   Sweet, Matthew J ^a   Blumenthal, Antje ^a   Powell, Elizabeth E ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

CDE; Ductular reaction; Liver fibrosis; Macrophages; Matrix remodelling; TAA

Indexed keywords

BETA CATENIN; COLLAGENASE 3; EPITHELIAL CELL ADHESION MOLECULE; MACROPHAGE ELASTASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CHRONIC LIVER INJURY; CONTROLLED STUDY; DISEASE EXACERBATION; DOWN REGULATION; EPCAM GENE; FEMALE; FIBROGENESIS; GENE; GENE DELETION; GENE EXPRESSION REGULATION; HEPATIC PROGENITOR CELL; LIVER FIBROSIS; LIVER INJURY; MACROPHAGE; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEX DIFFERENCE; SIGNAL TRANSDUCTION; UPREGULATION; WNTLESS GENE;

EID: 84944395643     PISSN: None     EISSN: 17551536     Source Type: Journal    
DOI: 10.1186/s13069-015-0036-7     Document Type: Article

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