Ultrasonic emulsification of parenteral valproic acid-loaded nanoemulsion with response surface methodology and evaluation of its stability

Ultrasonics Sonochemistry

Volumn 29, Issue , 2016, Pages 299-308

  Tan, Suk Fei ^a   Masoumi, Hamid Reza Fard ^a   Karjiban, Roghayeh Abedi ^a   Stanslas, Johnson ^a   Kirby, Brian P ^b   Basri, Mahiran ^a   Basri, Hamidon Bin ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^b ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

Author keywords

Blood brain barrier; Central composition design; Epilepsy; Nanoemulsion; Ultrasonication; Valproic acid

Indexed keywords

BLOOD; DROPS; NEUROLOGY; OILS AND FATS; OILSEEDS; PROCESSING; SONICATION; SURFACE ACTIVE AGENTS; SURFACE PROPERTIES; SYSTEM STABILITY; TRANSMISSION ELECTRON MICROSCOPY; VOLCANIC ROCKS;

BLOOD-BRAIN BARRIER; CENTRAL COMPOSITION DESIGN; EPILEPSY; NANOEMULSION; ULTRA-SONICATION; VALPROIC ACID;

EMULSIFICATION;

MEDIUM CHAIN TRIACYLGLYCEROL; PHOSPHATIDYLCHOLINE; POLYSORBATE 80; SAFFLOWER OIL; VALPROIC ACID; EMULSION; TRIACYLGLYCEROL;

ARTICLE; BIOCOMPATIBILITY; BLOOD BRAIN BARRIER; ELECTRON MICROSCOPE; NANOEMULSION; NANOFABRICATION; NANOPHARMACEUTICS; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RESPONSE SURFACE METHOD; SOUND INTENSITY; TRANSMISSION ELECTRON MICROSCOPY; ULTRASONIC EMULSIFICATION; ULTRASOUND; VISCOSITY; CHEMISTRY; DRUG ADMINISTRATION ROUTE; DRUG STABILITY; EMULSION; MEDICINAL CHEMISTRY; NANOTECHNOLOGY; PROCEDURES; STATISTICS;

CHEMISTRY, PHARMACEUTICAL; DRUG ADMINISTRATION ROUTES; DRUG STABILITY; EMULSIONS; NANOTECHNOLOGY; SAFFLOWER OIL; STATISTICS AS TOPIC; TRIGLYCERIDES; ULTRASONIC WAVES; VALPROIC ACID;

EID: 84944385947     PISSN: 13504177     EISSN: 18732828     Source Type: Journal    
DOI: 10.1016/j.ultsonch.2015.09.015     Document Type: Article

References (46)

1. I. Ojima Medicinal chemistry at a crossroads: challenges and new possibilities Future Med. Chem. 1 3 2009 401 403 10.4155/fmc.09.37
2. W. Löscher Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action Prog. Neurobiol. 58 1 1999 31 59 Available at: http://www.ncbi.nlm.nih.gov/pubmed/10321796
3. M.K. Trojnar, E. Wierzchowska-cioch, M. Krzy, and S.J. Czuczwar New generation of valproic acid Pol. J. Pharmacol. 56 2004 283 288
4. W. Löscher, and H.H. Frey Kinetics of penetration of common antiepileptic drugs into cerebrospinal fluid Epilepsia 25 3 1984 346 352 Available at: http://www.ncbi.nlm.nih.gov/pubmed/6723594 (accessed 11.05.2015)
5. J.H. Lin, and a.Y. Lu Role of pharmacokinetics and metabolism in drug discovery and development Pharmacol. Rev. 49 4 1997 403 449
6. N. Anton, J.-P. Benoit, and P. Saulnier Design and production of nanoparticles formulated from nano-emulsion templates-a review J. Controlled Release 128 3 2008 185 199 10.1016/j.jconrel.2008.02.007
7. J.V.L. Henry, P.J. Fryer, W.J. Frith, and I.T. Norton Food Hydrocolloids The influence of phospholipids and food proteins on the size and stability of model sub-micron emulsions Food Hydrocoll. 24 1 2010 66 71 10.1016/j.foodhyd.2009.08.006
8. S. Al-Edresi, and S. Baie Formulation and stability of whitening VCO-in-water nano-cream Int. J. Pharm. 373 1-2 2009 174 178 10.1016/j.ijpharm.2009.02.011
9. P. Shah, D. Bhalodia, and P. Shelat Nanoemulsion: a pharmaceutical review Syst. Rev. Pharm. 1 1 2010 24 10.4103/0975-8453.59509
10. N. Thakur, G. Garg, P.K. Sharma, and N. Kumar Nanoemulsions: a review on various pharmaceutical application Glob. J. Pharmacol. 6 3 2012 222 225 10.5829/idosi.gjp.2012.6.3.65135
11. C. Lovelyn Current state of nanoemulsions in drug delivery J. Biomater. Nanobiotechnol. 02 05 2011 626 639 10.4236/jbnb.2011.225075
12. J.M. Asua Miniemulsion polymerization Prog. Polym. Sci. 27 7 2002 1283 1346 10.1016/S0079-6700(02)00010-2
13. S.Y. Tang, P. Shridharan, and M. Sivakumar Impact of process parameters in the generation of novel aspirin nanoemulsions - comparative studies between ultrasound cavitation and microfluidizer Ultrason. Sonochem. 20 1 2013 485 497 10.1016/j.ultsonch.2012.04.005
14. T. Tadros, P. Izquierdo, J. Esquena, and C. Solans Formation and stability of nano-emulsions Adv. Colloid Interface Sci. 108-109 2004 303 318 10.1016/j.cis.2003.10.023
15. T.K. Vyas, A. Shahiwala, and M.M. Amiji Improved oral bioavailability and brain transport of Saquinavir upon administration in novel nanoemulsion formulations Int. J. Pharm. 347 1-2 2008 93 101 10.1016/j.ijpharm.2007.06.016
16. B. Abismaïl, J.P. Canselier, a.M. Wilhelm, H. Delmas, and C. Gourdon Emulsification by ultrasound: drop size distribution and stability Ultrason. Sonochem. 6 1-2 1999 75 83 Available at: http://www.ncbi.nlm.nih.gov/pubmed/11233941
17. D.M. Higgins, and D.M. Skauen Influence of power on quality of emulsions prepared by ultrasound J. Pharm. Sci. 61 10 1972 1567 1570 Available at: http://www.ncbi.nlm.nih.gov/pubmed/5072401 (accessed 12.05.2015)
18. W. Wu, Parenteral nanoemulsions - composition, preparation and cellular uptake, 2007.
19. Z. Kobus Influence of physical properties of liquid on acoustic power of ultrasonic processor TEKA Kom. Mot. Energy Roln. 8a 2008 71 78
20. M.A. Bezerra, R.E. Santelli, E.P. Oliveira, L.S. Villar, and L.a. Escaleira Response surface methodology (RSM) as a tool for optimization in analytical chemistry Talanta 76 5 2008 965 977 10.1016/j.talanta.2008.05.019
21. M.-M. Song, C. Branford-White, H.-L. Nie, and L.-M. Zhu Optimization of adsorption conditions of BSA on thermosensitive magnetic composite particles using response surface methodology Colloids Surf., B Biointerfaces 84 2 2011 477 483 10.1016/j.colsurfb.2011.02.002
22. D.C. Montgomery, Design and Analysis of Experiments, sixth ed., 2000, http://dx.doi.org/978-0-470-56319-9. Available at: http://bcs.wiley.com/he-bcs/Books?action=index&itemId=047148735X&itemTypeId=BKS&bcsId=2172 (accessed 10.09.2015).
23. S.H. Musa, M. Basri, H.R.F. Masoumi, and et al. Formulation optimization of palm kernel oil esters nanoemulsion-loaded with chloramphenicol suitable for meningitis treatment Colloids Surf., B Biointerfaces 112 2013 113 119 10.1016/j.colsurfb.2013.07.043
24. S. Zainol, M. Basri, Basri H. Bin, and et al. Formulation optimization of a palm-based nanoemulsion system containing levodopa Int. J. Mol. Sci. 13 10 2012 13049 13064 10.3390/ijms131013049
25. J.A. Hamilton, and K. Brunaldi A model for fatty acid transport into the brain J. Mol. Neurosci. 33 1 2007 12 17 Available at: http://www.ncbi.nlm.nih.gov/pubmed/17901540 (accessed 30.03.2015)
26. W. Warisnoicharoen, a.B. Lansley, and M.J. Lawrence Nonionic oil-in-water microemulsions: the effect of oil type on phase behaviour Int. J. Pharm. 198 1 2000 7 27 Available at: http://www.ncbi.nlm.nih.gov/pubmed/10722947
27. G. Chansiri, R.T. Lyons, M.V. Patel, and S.L. Hem Effect of surface charge on the stability of oil/water emulsions during steam sterilization J. Pharm. Sci. 88 4 1999 454 458 10.1021/js980293i
28. P. Kandadi, M.A. Syed, S. Goparaboina, and K. Veerabrahma Brain specific delivery of pegylated indinavir submicron lipid emulsions Eur. J. Pharm. Sci. 42 4 2011 423 432 10.1016/j.ejps.2011.01.008
29. S. Ganta, P. Sharma, J.W. Paxton, B.C. Baguley, and S. Garg Pharmacokinetics and pharmacodynamics of chlorambucil delivered in long-circulating nanoemulsion J. Drug Target. 2010 18 2009 125 133 10.3109/10611860903244199
30. F.a. Araújo, R.G. Kelmann, B.V. Araújo, R.B. Finatto, H.F. Teixeira, and L.S. Koester Development and characterization of parenteral nanoemulsions containing thalidomide Eur. J. Pharm Sci. 42 3 2011 238 245 10.1016/j.ejps.2010.11.014
31. 2 J. Food Eng. 92 4 2009 370 376 10.1016/j.jfoodeng.2008.12.002
32. Y. Cao, M. Marra, and B.D. Anderson Predictive relationships for the effects of triglyceride ester concentration and water uptake on solubility and partitioning of small molecules into lipid vehicles J. Pharm. Sci. 93 11 2004 2768 2779 10.1002/jps.20126
33. C.B. Woitiski, F. Veiga, A. Ribeiro, and R. Neufeld Design for optimization of nanoparticles integrating biomaterials for orally dosed insulin Eur. J. Pharm. Biopharm. 73 1 2009 25 33 10.1016/j.ejpb.2009.06.002
34. S.K. Motwani, S. Chopra, S. Talegaonkar, K. Kohli, F.J. Ahmad, and R.K. Khar Chitosan-sodium alginate nanoparticles as submicroscopic reservoirs for ocular delivery: formulation, optimisation and in vitro characterisation Eur. J. Pharm. Biopharm. 68 3 2008 513 525 10.1016/j.ejpb.2007.09.009
35. C. Preetz, A. Hauser, G. Hause, A. Kramer, and K. Mäder Application of atomic force microscopy and ultrasonic resonator technology on nanoscale: distinction of nanoemulsions from nanocapsules Eur. J. Pharm. Sci. 39 1-3 2010 141 151 10.1016/j.ejps.2009.11.009
36. A. Joglekar, and A. May Product excellence through design of experiments Cereal Foods World 32 12 1987 857 868
37. P.R. Gogate, and A.B. Pandit Hydrodynamic caviation reactors: a state of the art review Rev. Chem. Eng. 17 1 2001 1 85 10.1515/REVCE.2001.17.1.1
38. S.Y. Tang, S. Manickam, T.K. Wei, and B. Nashiru Formulation development and optimization of a novel Cremophore EL-based nanoemulsion using ultrasound cavitation Ultrason. Sonochem. 19 2 2012 330 345 10.1016/j.ultsonch.2011.07.001
39. T.S.H. Leong, T.J. Wooster, S.E. Kentish, and M. Ashokkumar Minimising oil droplet size using ultrasonic emulsification Ultrason. Sonochem. 16 6 2009 721 727 10.1016/j.ultsonch.2009.02.008
40. S.G. Gaikwad, and A.B. Pandit Ultrasound emulsification: effect of ultrasonic and physicochemical properties on dispersed phase volume and droplet size Ultrason. Sonochem. 15 4 2008 554 563 10.1016/j.ultsonch.2007.06.011
41. S.M. Jafari, Y. He, and B. Bhandari Production of sub-micron emulsions by ultrasound and microfluidization techniques J. Food Eng. 82 4 2007 478 488 10.1016/j.jfoodeng.2007.03.007
42. K.A. Ramisetty, and R. Shyamsunder Effect of ultrasonication on stability of oil in water emulsions Int. J. Drug Deliv. 3 2011 133 142
43. V. Klang, C. Valenta, and N.B. Matsko Electron microscopy of pharmaceutical systems Micron 44 2013 45 74 10.1016/j.micron.2012.07.008
44. G.H. Woehrle, J.E. Hutchison, S. Ozkar, and R.G. Finke Analysis of nanoparticle transmission electron microscopy data using a public-domain image-processing program, ImageJ Turkish J. Chem. 30 2006 1 13
45. R.H. Müller, S. Schmidt, I. Buttle, A. Akkar, J. Schmitt, and S. Brömer SolEmuls® - novel technology for the formulation of i.v. emulsions with poorly soluble drugs Int. J. Pharm. 269 2 2004 293 302 10.1016/j.ijpharm.2003.09.019
46. V. Klang, and C. Valenta Lecithin-based nanoemulsions J. Drug Deliv. Sci. Technol. 21 1 2011 55 76