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Volumn 112, Issue , 2013, Pages 113-119
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Formulation optimization of palm kernel oil esters nanoemulsion-loaded with chloramphenicol suitable for meningitis treatment
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Author keywords
Blood brain barrier (BBB); Central composite design (CCD); Chloramphenicol; Meningitis; Nanoemulsion; Response surface methodology (RSM)
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Indexed keywords
BLOOD-BRAIN BARRIER;
CENTRAL COMPOSITE DESIGNS;
CHLORAMPHENICOL;
MENINGITIS;
NANOEMULSION;
RESPONSE SURFACE METHODOLOGY;
ANTIBIOTICS;
BLOOD;
EMULSIFICATION;
ESTERIFICATION;
ESTERS;
MULTIVARIANT ANALYSIS;
OPTIMIZATION;
PARTICLE SIZE;
POLYDISPERSITY;
SURFACE PROPERTIES;
ZETA POTENTIAL;
PALM OIL;
CHLORAMPHENICOL;
DRUG CARRIER;
GLYCEROL;
OIL;
PALM KERNEL OIL ESTER DERIVATIVE;
PHOSPHATIDYLCHOLINE;
SESAME SEED OIL;
UNCLASSIFIED DRUG;
ARTICLE;
BLOOD BRAIN BARRIER;
CENTRAL COMPOSITE DESIGN;
DRUG FORMULATION;
DRUG SOLUBILITY;
INDEPENDENT VARIABLE;
MENINGITIS;
METHODOLOGY;
NANOEMULSION;
OSMOLALITY;
PARTICLE SIZE;
PHYSICAL CHEMISTRY;
PHYSICAL PARAMETERS;
POLYDISPERSITY INDEX;
PREDICTION;
PRIORITY JOURNAL;
PROCESS OPTIMIZATION;
RESPONSE SURFACE METHOD;
TREATMENT INDICATION;
ZETA POTENTIAL;
BLOOD-BRAIN BARRIER (BBB);
CENTRAL COMPOSITE DESIGN (CCD);
CHLORAMPHENICOL;
MENINGITIS;
NANOEMULSION;
RESPONSE SURFACE METHODOLOGY (RSM);
ANTI-BACTERIAL AGENTS;
BLOOD-BRAIN BARRIER;
CHEMISTRY, PHARMACEUTICAL;
CHLORAMPHENICOL;
DRUG CARRIERS;
EMULSIONS;
GLYCEROL;
HUMANS;
LECITHINS;
MENINGITIS, BACTERIAL;
NANOSTRUCTURES;
OSMOLAR CONCENTRATION;
PARTICLE SIZE;
PLANT OILS;
SOLUBILITY;
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EID: 84883170322
PISSN: 09277765
EISSN: 18734367
Source Type: Journal
DOI: 10.1016/j.colsurfb.2013.07.043 Document Type: Article |
Times cited : (72)
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References (41)
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