TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 41, 2015, Pages 12800-12805

  Fujii, Toshihiro ^a,b   Sakata, Asuka ^c   Nishimura, Satoshi ^c,d   Eto, Koji ^e   Nagata, Shigekazu ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e KYOTO UNIVERSITY   (Japan)

Author keywords

Calcium; Microvesicles; Phosphatidylserine; Platelets; Scramblase

Indexed keywords

CALCIUM ION; CALCIUM IONOPHORE; COLLAGEN; MEMBRANE PROTEIN; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PROTEIN TMEM16F; THROMBIN; THROMBOPLASTIN; UNCLASSIFIED DRUG; CALCIUM; PHOSPHOLIPID TRANSFER PROTEIN; TMEM16F PROTEIN, HUMAN; TMEM16F PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOD CLOT RETRACTION; BLOOD CLOTTING; CELL GRANULE; CELL MEMBRANE; CONFERENCE PAPER; CONTROLLED STUDY; GENE DELETION; HUMAN; HUMAN CELL; IN VIVO STUDY; LASER; MEMBRANE MICROPARTICLE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; ANIMAL; BLOOD CLOTTING DISORDER; DISEASE MODEL; GENETICS; METABOLISM; MUTANT MOUSE STRAIN; PATHOLOGY; SECRETION (PROCESS);

ANIMALS; BLOOD COAGULATION; BLOOD COAGULATION DISORDERS; BLOOD PLATELETS; CALCIUM; CELL-DERIVED MICROPARTICLES; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, MUTANT STRAINS; PHOSPHATIDYLSERINES; PHOSPHOLIPID TRANSFER PROTEINS; PLATELET ACTIVATION; THROMBIN;

EID: 84944183128     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1516594112     Document Type: Article

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