-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
D.C. Angus, W.T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M.R. Pinsky Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care Crit Care Med 29 2001 1303
-
(2001)
Crit Care Med
, vol.29
, pp. 1303
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
2
-
-
84899750488
-
A randomized trial of protocol-based care for early septic shock
-
D.M. Yealy, J.A. Kellum, D.T. Huang, and et al. A randomized trial of protocol-based care for early septic shock N Engl J Med 370 2014 1683
-
(2014)
N Engl J Med
, vol.370
, pp. 1683
-
-
Yealy, D.M.1
Kellum, J.A.2
Huang, D.T.3
-
3
-
-
84908059020
-
Goal-directed resuscitation for patients with early septic shock
-
S.L. Peake, A. Delaney, M. Bailey, and et al. Goal-directed resuscitation for patients with early septic shock N Engl J Med 371 2014 1496
-
(2014)
N Engl J Med
, vol.371
, pp. 1496
-
-
Peake, S.L.1
Delaney, A.2
Bailey, M.3
-
4
-
-
84991010642
-
Mortality in the United States, 2012
-
J. Xu, K.D. Kochanek, S.L. Murphy, and E. Arias Mortality in the United States, 2012 NCHS Data Brief 2014 1
-
(2014)
NCHS Data Brief
, pp. 1
-
-
Xu, J.1
Kochanek, K.D.2
Murphy, S.L.3
Arias, E.4
-
5
-
-
37549020378
-
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
-
R.P. Dellinger, M.M. Levy, J.M. Carlet, and et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008 Crit Care Med 36 2008 296
-
(2008)
Crit Care Med
, vol.36
, pp. 296
-
-
Dellinger, R.P.1
Levy, M.M.2
Carlet, J.M.3
-
6
-
-
84925723236
-
Surviving sepsis campaign: Association between performance metrics and outcomes in a 7.5-year study
-
M.M. Levy, A. Rhodes, G.S. Phillips, and et al. Surviving sepsis campaign: association between performance metrics and outcomes in a 7.5-year study Crit Care Med 43 2015 3 12
-
(2015)
Crit Care Med
, vol.43
, pp. 3-12
-
-
Levy, M.M.1
Rhodes, A.2
Phillips, G.S.3
-
9
-
-
47849130092
-
Cytomegalovirus reactivation in critically ill immunocompetent patients
-
A.P. Limaye, K.A. Kirby, G.D. Rubenfeld, and et al. Cytomegalovirus reactivation in critically ill immunocompetent patients JAMA 300 2008 413
-
(2008)
JAMA
, vol.300
, pp. 413
-
-
Limaye, A.P.1
Kirby, K.A.2
Rubenfeld, G.D.3
-
10
-
-
84255183707
-
The search for effective therapy for sepsis: Back to the drawing board?
-
D.C. Angus The search for effective therapy for sepsis: back to the drawing board? JAMA 306 2011 2614
-
(2011)
JAMA
, vol.306
, pp. 2614
-
-
Angus, D.C.1
-
11
-
-
84902511727
-
The next generation of sepsis clinical trial designs: What is next after the demise of recombinant human activated protein C?∗
-
S.M. Opal, R.P. Dellinger, J.L. Vincent, H. Masur, and D.C. Angus The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?∗ Crit Care Med 42 2014 1714
-
(2014)
Crit Care Med
, vol.42
, pp. 1714
-
-
Opal, S.M.1
Dellinger, R.P.2
Vincent, J.L.3
Masur, H.4
Angus, D.C.5
-
13
-
-
47649124819
-
Comparison of WBC, ESR, CRP and PCT serum levels in septic and non-septic burn cases
-
M. Barati, F. Alinejad, M.A. Bahar, and et al. Comparison of WBC, ESR, CRP and PCT serum levels in septic and non-septic burn cases Burns 34 2008 770
-
(2008)
Burns
, vol.34
, pp. 770
-
-
Barati, M.1
Alinejad, F.2
Bahar, M.A.3
-
14
-
-
67650486328
-
Stratification is the key: Inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis
-
M.F. Osuchowski, J. Connett, K. Welch, J. Granger, and D.G. Remick Stratification is the key: inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis Crit Care Med 37 2009 1567
-
(2009)
Crit Care Med
, vol.37
, pp. 1567
-
-
Osuchowski, M.F.1
Connett, J.2
Welch, K.3
Granger, J.4
Remick, D.G.5
-
15
-
-
79953292076
-
Cecal ligation and puncture: The gold standard model for polymicrobial sepsis?
-
L. Dejager, I. Pinheiro, E. Dejonckheere, and C. Libert Cecal ligation and puncture: the gold standard model for polymicrobial sepsis? Trends Microbiol 19 2011 198
-
(2011)
Trends Microbiol
, vol.19
, pp. 198
-
-
Dejager, L.1
Pinheiro, I.2
Dejonckheere, E.3
Libert, C.4
-
17
-
-
68949083424
-
The cannabinoid receptor 2 is critical for the host response to sepsis
-
J. Tschop, K.R. Kasten, R. Nogueiras, and et al. The cannabinoid receptor 2 is critical for the host response to sepsis J Immunol 183 2009 499
-
(2009)
J Immunol
, vol.183
, pp. 499
-
-
Tschop, J.1
Kasten, K.R.2
Nogueiras, R.3
-
18
-
-
0020520054
-
Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model
-
C.C. Baker, I.H. Chaudry, H.O. Gaines, and A.E. Baue Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model Surgery 94 1983 331
-
(1983)
Surgery
, vol.94
, pp. 331
-
-
Baker, C.C.1
Chaudry, I.H.2
Gaines, H.O.3
Baue, A.E.4
-
19
-
-
0018939290
-
Effect of adenosine triphosphate-glucose administration following sepsis
-
I.H. Chaudry, H. Hirasawa, and A.E. Baue Effect of adenosine triphosphate-glucose administration following sepsis J Surg Res 29 1980 348
-
(1980)
J Surg Res
, vol.29
, pp. 348
-
-
Chaudry, I.H.1
Hirasawa, H.2
Baue, A.E.3
-
20
-
-
33645379921
-
Differential effect of imipenem treatment on wild-type and NK cell-deficient CD8 knockout mice during acute intra-abdominal injury
-
V.T. Enoh, C.D. Fairchild, C.Y. Lin, T.K. Varma, and E.R. Sherwood Differential effect of imipenem treatment on wild-type and NK cell-deficient CD8 knockout mice during acute intra-abdominal injury Am J Physiol Regul Integr Comp Physiol 290 2006 R685
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.290
, pp. R685
-
-
Enoh, V.T.1
Fairchild, C.D.2
Lin, C.Y.3
Varma, T.K.4
Sherwood, E.R.5
-
21
-
-
42149164364
-
CD4-expressing cells are early mediators of the innate immune system during sepsis
-
A. Martignoni, J. Tschop, H.S. Goetzman, and et al. CD4-expressing cells are early mediators of the innate immune system during sepsis Shock 29 2008 591
-
(2008)
Shock
, vol.29
, pp. 591
-
-
Martignoni, A.1
Tschop, J.2
Goetzman, H.S.3
-
22
-
-
43349102405
-
Gammadelta T cells mitigate the organ injury and mortality of sepsis
-
J. Tschop, A. Martignoni, H.S. Goetzman, and et al. Gammadelta T cells mitigate the organ injury and mortality of sepsis J Leukoc Biol 83 2008 581
-
(2008)
J Leukoc Biol
, vol.83
, pp. 581
-
-
Tschop, J.1
Martignoni, A.2
Goetzman, H.S.3
-
24
-
-
0026040438
-
Membrane surface antigen expression on neutrophils: A reappraisal of the use of surface markers for neutrophil activation
-
T.W. Kuijpers, A.T. Tool, C.E. van der Schoot, and et al. Membrane surface antigen expression on neutrophils: a reappraisal of the use of surface markers for neutrophil activation Blood 78 1991 1105
-
(1991)
Blood
, vol.78
, pp. 1105
-
-
Kuijpers, T.W.1
Tool, A.T.2
Van Der Schoot, C.E.3
-
25
-
-
0033195352
-
The alphaMbeta2 integrin and its role in neutrophil function
-
Z. Li The alphaMbeta2 integrin and its role in neutrophil function Cell Res 9 1999 171
-
(1999)
Cell Res
, vol.9
, pp. 171
-
-
Li, Z.1
-
26
-
-
77957691402
-
T-cell activation differentially mediates the host response to sepsis
-
K.R. Kasten, J. Tschop, H.S. Goetzman, and et al. T-cell activation differentially mediates the host response to sepsis Shock 34 2010 377
-
(2010)
Shock
, vol.34
, pp. 377
-
-
Kasten, K.R.1
Tschop, J.2
Goetzman, H.S.3
-
27
-
-
84890564250
-
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
-
Y. Furusawa, Y. Obata, S. Fukuda, and et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells Nature 504 2013 446
-
(2013)
Nature
, vol.504
, pp. 446
-
-
Furusawa, Y.1
Obata, Y.2
Fukuda, S.3
-
28
-
-
0033969341
-
Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options
-
C.A. Gogos, E. Drosou, H.P. Bassaris, and A. Skoutelis Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options J Infect Dis 181 2000 176
-
(2000)
J Infect Dis
, vol.181
, pp. 176
-
-
Gogos, C.A.1
Drosou, E.2
Bassaris, H.P.3
Skoutelis, A.4
-
31
-
-
42949131678
-
Ron receptor tyrosine kinase-dependent hepatic neutrophil recruitment and survival benefit in a murine model of bacterial peritonitis
-
C.C. Caldwell, A. Martignoni, M.A. Leonis, H.K. Ondiveeran, A.E. Fox-Robichaud, and S.E. Waltz Ron receptor tyrosine kinase-dependent hepatic neutrophil recruitment and survival benefit in a murine model of bacterial peritonitis Crit Care Med 36 2008 1585
-
(2008)
Crit Care Med
, vol.36
, pp. 1585
-
-
Caldwell, C.C.1
Martignoni, A.2
Leonis, M.A.3
Ondiveeran, H.K.4
Fox-Robichaud, A.E.5
Waltz, S.E.6
-
32
-
-
36849008476
-
Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival
-
M. Thiel, C.C. Caldwell, S. Kreth, and et al. Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival PloS One 2 2007 e853
-
(2007)
PloS One
, vol.2
, pp. e853
-
-
Thiel, M.1
Caldwell, C.C.2
Kreth, S.3
-
33
-
-
34250890817
-
Pathophysiology of sepsis
-
D.G. Remick Pathophysiology of sepsis Am J Pathol 170 2007 1435
-
(2007)
Am J Pathol
, vol.170
, pp. 1435
-
-
Remick, D.G.1
-
34
-
-
84904396536
-
Genetic polymorphisms and sepsis in premature neonates
-
S. Esposito, A. Zampiero, L. Pugni, and et al. Genetic polymorphisms and sepsis in premature neonates PloS One 9 2014 e101248
-
(2014)
PloS One
, vol.9
, pp. e101248
-
-
Esposito, S.1
Zampiero, A.2
Pugni, L.3
-
35
-
-
84901689664
-
The beginning of personalized medicine in sepsis: Small steps to a bright future
-
E. Christaki, and E.J. Giamarellos-Bourboulis The beginning of personalized medicine in sepsis: small steps to a bright future Clin Genet 86 2014 56
-
(2014)
Clin Genet
, vol.86
, pp. 56
-
-
Christaki, E.1
Giamarellos-Bourboulis, E.J.2
-
36
-
-
78650624395
-
Genome-wide transcription profiling of human sepsis: A systematic review
-
B.M. Tang, S.J. Huang, and A.S. McLean Genome-wide transcription profiling of human sepsis: a systematic review Crit Care 14 2010 R237
-
(2010)
Crit Care
, vol.14
, pp. R237
-
-
Tang, B.M.1
Huang, S.J.2
McLean, A.S.3
-
37
-
-
1242320032
-
Genomic polymorphisms in sepsis
-
M.T. Lin, and T.E. Albertson Genomic polymorphisms in sepsis Crit Care Med 32 2004 569
-
(2004)
Crit Care Med
, vol.32
, pp. 569
-
-
Lin, M.T.1
Albertson, T.E.2
-
38
-
-
84255194001
-
Immunosuppression in patients who die of sepsis and multiple organ failure
-
J.S. Boomer, K. To, K.C. Chang, and et al. Immunosuppression in patients who die of sepsis and multiple organ failure JAMA 306 2011 2594
-
(2011)
JAMA
, vol.306
, pp. 2594
-
-
Boomer, J.S.1
To, K.2
Chang, K.C.3
-
39
-
-
0030843156
-
Sepsis: A new hypothesis for pathogenesis of the disease process
-
R.C. Bone, C.J. Grodzin, and R.A. Balk Sepsis: a new hypothesis for pathogenesis of the disease process Chest 112 1997 235
-
(1997)
Chest
, vol.112
, pp. 235
-
-
Bone, R.C.1
Grodzin, C.J.2
Balk, R.A.3
-
40
-
-
84915807918
-
Assessing the immune status of critically ill trauma patients by flow cytometry
-
J.W. Kuethe, R. Mintz-Cole, B.L. Johnson 3rd, E.F. Midura, C.C. Caldwell, and B.S. Schneider Assessing the immune status of critically ill trauma patients by flow cytometry Nurse Res 63 2014 426
-
(2014)
Nurse Res
, vol.63
, pp. 426
-
-
Kuethe, J.W.1
Mintz-Cole, R.2
Johnson, B.L.3
Midura, E.F.4
Caldwell, C.C.5
Schneider, B.S.6
-
42
-
-
84874457770
-
Genomic responses in mouse models poorly mimic human inflammatory diseases
-
J. Seok, H.S. Warren, A.G. Cuenca, and et al. Genomic responses in mouse models poorly mimic human inflammatory diseases Proc Natl Acad Sci U S A 110 2013 3507
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 3507
-
-
Seok, J.1
Warren, H.S.2
Cuenca, A.G.3
-
43
-
-
84901626481
-
Abandon the mouse research ship? Not just yet!
-
M.F. Osuchowski, D.G. Remick, J.A. Lederer, and et al. Abandon the mouse research ship? Not just yet! Shock 41 2014 463
-
(2014)
Shock
, vol.41
, pp. 463
-
-
Osuchowski, M.F.1
Remick, D.G.2
Lederer, J.A.3
|