Syntheses and evaluation of substituted aromatic hydroxamates and hydroxamic acids that target Mycobacterium tuberculosis

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 21, 2015, Pages 4933-4936

  Majewski, Mark W ^a   Cho, Sanghyun ^b   Miller, Patricia A ^a   Franzblau, Scott G ^b   Miller, Marvin J ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Hydroxamate; Hydroxamic acid; Tuberculosis

Indexed keywords

HYDROXAMIC ACID; HYDROXAMIC ACID DERIVATIVE; AROMATIC HYDROCARBON; TUBERCULOSTATIC AGENT;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; RESAZURIN ASSAY; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROCARBONS, AROMATIC; HYDROXAMIC ACIDS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE-ACTIVITY RELATIONSHIP; TUBERCULOSIS;

EID: 84944159275     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.04.099     Document Type: Article

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