-
1
-
-
84877137455
-
Hepatocellular carcinoma: western and eastern surgeons' points of view
-
Vibert E, Ishizawa T. Hepatocellular carcinoma: western and eastern surgeons' points of view. J. Visc. Surg. 2012;149:e302-e306.
-
(2012)
J. Visc. Surg.
, vol.149
, pp. e302-e306
-
-
Vibert, E.1
Ishizawa, T.2
-
2
-
-
84901632287
-
Multimodal treatment of hepatocellular carcinoma
-
Graf D, Vallböhmer D, Knoefel WT, Kröpil P, Antoch G, Sagir A, Häussinger D. Multimodal treatment of hepatocellular carcinoma. Eur. J. Intern. Med. 2014;25:430-437.
-
(2014)
Eur. J. Intern. Med.
, vol.25
, pp. 430-437
-
-
Graf, D.1
Vallböhmer, D.2
Knoefel, W.T.3
Kröpil, P.4
Antoch, G.5
Sagir, A.6
Häussinger, D.7
-
3
-
-
84859973897
-
Improved chemotherapy for hepatocellular carcinoma
-
Cao H, Phan H, Yang LX. Improved chemotherapy for hepatocellular carcinoma. Anticancer Res. 2012;32:1379-1386.
-
(2012)
Anticancer Res.
, vol.32
, pp. 1379-1386
-
-
Cao, H.1
Phan, H.2
Yang, L.X.3
-
4
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
Hennessy BT, Smith DL, Ram PT, Lu Y, Mills GB. Exploiting the PI3K/AKT pathway for cancer drug discovery. Nat. Rev. Drug Discov. 2005;4:988-1004.
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
Lu, Y.4
Mills, G.B.5
-
5
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005;307:1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
6
-
-
0031039024
-
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
-
Franke TF, Kaplan DR, Cantley LC, Toker A. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3, 4-bisphosphate. Science 1997;275:665-668.
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
Toker, A.4
-
7
-
-
33646253672
-
Akt signaling and cancer: surviving but not moving on
-
Toker A, Yoeli-Lerner M. Akt signaling and cancer: surviving but not moving on. Cancer Res. 2006;66:3963-3966.
-
(2006)
Cancer Res.
, vol.66
, pp. 3963-3966
-
-
Toker, A.1
Yoeli-Lerner, M.2
-
8
-
-
84918839180
-
Targeting the genetic alterations of the PI3K-AKT-mTOR pathway: its potential use in the treatment of bladder cancers
-
Houédé N, Pourquier P. Targeting the genetic alterations of the PI3K-AKT-mTOR pathway: its potential use in the treatment of bladder cancers. Pharmacol. Ther. 2015;145:1-18.
-
(2015)
Pharmacol. Ther.
, vol.145
, pp. 1-18
-
-
Houédé, N.1
Pourquier, P.2
-
9
-
-
22544455676
-
Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase
-
Holz MK, Blenis J. Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase. J. Biol. Chem. 2005;280:26089-26093.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26089-26093
-
-
Holz, M.K.1
Blenis, J.2
-
10
-
-
84876794946
-
Pathways and targets in hepatocellular carcinoma
-
Psyrri A, Arkadopoulos N, Vassilakopoulou M, Smyrniotis V, Dimitriadis G. Pathways and targets in hepatocellular carcinoma. Expert Rev. Anticancer Ther. 2012;12:1347-1357.
-
(2012)
Expert Rev. Anticancer Ther.
, vol.12
, pp. 1347-1357
-
-
Psyrri, A.1
Arkadopoulos, N.2
Vassilakopoulou, M.3
Smyrniotis, V.4
Dimitriadis, G.5
-
11
-
-
84877814354
-
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages
-
Hyam SR, Lee IA, Gu W, Kim KA, Jeong JJ, Jang SE, Han MJ, Kim DH. Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages. Eur. J. Pharmacol. 2013;708:21-29
-
(2013)
Eur. J. Pharmacol.
, vol.708
, pp. 21-29
-
-
Hyam, S.R.1
Lee, I.A.2
Gu, W.3
Kim, K.A.4
Jeong, J.J.5
Jang, S.E.6
Han, M.J.7
Kim, D.H.8
-
12
-
-
79960178328
-
Arctigenin enhances chemosensitivity of cancer cells to cisplatin through inhibition of the STAT3 signaling pathway
-
Yao X, Zhu F, Zhao Z, Liu C, Luo L, Yin Z. Arctigenin enhances chemosensitivity of cancer cells to cisplatin through inhibition of the STAT3 signaling pathway. J. Cell Biochem. 2011;112:2837-2849.
-
(2011)
J. Cell Biochem.
, vol.112
, pp. 2837-2849
-
-
Yao, X.1
Zhu, F.2
Zhao, Z.3
Liu, C.4
Luo, L.5
Yin, Z.6
-
13
-
-
77952502347
-
Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity
-
Kim JY, Hwang JH, Cha MR, Yoon MY, Son ES, Tomida A, Ko B, Song SW, Shin-ya K, Hwang YI, Park HR. Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity. J. Cell Physiol. 2010;224:33-40.
-
(2010)
J. Cell Physiol.
, vol.224
, pp. 33-40
-
-
Kim, J.Y.1
Hwang, J.H.2
Cha, M.R.3
Yoon, M.Y.4
Son, E.S.5
Tomida, A.6
Ko, B.7
Song, S.W.8
Shin-ya, K.9
Hwang, Y.I.10
Park, H.R.11
-
14
-
-
84881044550
-
Inhibition of angiogenesis: a novel antitumor mechanism of the herbal compound arctigenin
-
Gu Y, Scheuer C, Feng D, Menger MD, Laschke MW. Inhibition of angiogenesis: a novel antitumor mechanism of the herbal compound arctigenin. Anticancer Drugs 2013;24:781-791.
-
(2013)
Anticancer Drugs
, vol.24
, pp. 781-791
-
-
Gu, Y.1
Scheuer, C.2
Feng, D.3
Menger, M.D.4
Laschke, M.W.5
-
15
-
-
84863549883
-
Arctigenin anti-tumor activity in bladder cancer T24 cell line through induction of cell-cycle arrest and apoptosis
-
Yang S, Ma J, Xiao J, Lv X, Li X, Yang H, Liu Y, Feng S, Zhang Y. Arctigenin anti-tumor activity in bladder cancer T24 cell line through induction of cell-cycle arrest and apoptosis. Anat. Rec (Hoboken) 2012;295:1260-1266.
-
(2012)
Anat. Rec (Hoboken)
, vol.295
, pp. 1260-1266
-
-
Yang, S.1
Ma, J.2
Xiao, J.3
Lv, X.4
Li, X.5
Yang, H.6
Liu, Y.7
Feng, S.8
Zhang, Y.9
-
16
-
-
84864149974
-
Arctigenin preferentially induces tumor cell death under glucose deprivation by inhibiting cellular energy metabolism
-
Gu Y, Qi C, Sun X, Ma X, Zhang H, Hu L, Yuan J, Yu Q. Arctigenin preferentially induces tumor cell death under glucose deprivation by inhibiting cellular energy metabolism. Biochem. Pharmacol. 2012;84:468-476.
-
(2012)
Biochem. Pharmacol.
, vol.84
, pp. 468-476
-
-
Gu, Y.1
Qi, C.2
Sun, X.3
Ma, X.4
Zhang, H.5
Hu, L.6
Yuan, J.7
Yu, Q.8
-
17
-
-
84872808323
-
Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cells
-
Cuconati A, Mills C, Goddard C, Zhang X, Yu W, Guo H, Xu X, Block TM. Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cells. PLoS One 2013;8:e54595.
-
(2013)
PLoS One
, vol.8
, pp. e54595
-
-
Cuconati, A.1
Mills, C.2
Goddard, C.3
Zhang, X.4
Yu, W.5
Guo, H.6
Xu, X.7
Block, T.M.8
-
18
-
-
84891632136
-
Arctigenin enhances chemosensitivity to cisplatin in human nonsmall lung cancer H460 cells through downregulation of survivin expression
-
Wang HQ, Jin JJ, Wang J. Arctigenin enhances chemosensitivity to cisplatin in human nonsmall lung cancer H460 cells through downregulation of survivin expression. J. Biochem. Mol. Toxicol. 2014;28:39-45.
-
(2014)
J. Biochem. Mol. Toxicol.
, vol.28
, pp. 39-45
-
-
Wang, H.Q.1
Jin, J.J.2
Wang, J.3
-
19
-
-
84888111708
-
Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation
-
Hsieh CJ, Kuo PL, Hsu YC, Huang YF, Tsai EM, Hsu YL. Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation. Free Radic. Biol. Med. 2014;67:159-170.
-
(2014)
Free Radic. Biol. Med.
, vol.67
, pp. 159-170
-
-
Hsieh, C.J.1
Kuo, P.L.2
Hsu, Y.C.3
Huang, Y.F.4
Tsai, E.M.5
Hsu, Y.L.6
-
20
-
-
80053241183
-
Arctigenin induces cell cycle arrest by blocking the phosphorylation of Rb via the modulation of cell cycle regulatory proteins in human gastric cancer cells
-
Jeong JB, Hong SC, Jeong HJ, Koo JS. Arctigenin induces cell cycle arrest by blocking the phosphorylation of Rb via the modulation of cell cycle regulatory proteins in human gastric cancer cells. Int. Immunopharmacol. 2011;11:1573-1577.
-
(2011)
Int. Immunopharmacol.
, vol.11
, pp. 1573-1577
-
-
Jeong, J.B.1
Hong, S.C.2
Jeong, H.J.3
Koo, J.S.4
-
21
-
-
84925937934
-
Arctigenin promotes apoptosis in ovarian cancer cells via the iNOS/NO/STAT3/survivin signalling
-
Huang K, Li LA, Meng YG, You YQ, Fu XY, Song L. Arctigenin promotes apoptosis in ovarian cancer cells via the iNOS/NO/STAT3/survivin signalling. Basic Clin. Pharmacol. Toxicol. 2014;115:507-511.
-
(2014)
Basic Clin. Pharmacol. Toxicol.
, vol.115
, pp. 507-511
-
-
Huang, K.1
Li, L.A.2
Meng, Y.G.3
You, Y.Q.4
Fu, X.Y.5
Song, L.6
-
22
-
-
84919387854
-
The inhibition of activated hepatic stellate cells proliferation by arctigenin through G0/G1 phase cell cycle arrest: persistent p27(Kip1) induction by interfering with PI3K/Akt/FOXO3a signaling pathway
-
Li A, Wang J, Wu M, Zhang X, Zhang H. The inhibition of activated hepatic stellate cells proliferation by arctigenin through G0/G1 phase cell cycle arrest: persistent p27(Kip1) induction by interfering with PI3K/Akt/FOXO3a signaling pathway. Eur. J. Pharmacol. 2015;747:71-87.
-
(2015)
Eur. J. Pharmacol.
, vol.747
, pp. 71-87
-
-
Li, A.1
Wang, J.2
Wu, M.3
Zhang, X.4
Zhang, H.5
-
23
-
-
84922760249
-
Arctigenin in combination with quercetin synergistically enhances the antiproliferative effect in prostate cancer cells
-
Wang P, Phan T, Gordon D, Chung S, Henning SM, Vadgama JV. Arctigenin in combination with quercetin synergistically enhances the antiproliferative effect in prostate cancer cells. Mol. Nutr. Food Res. 2015;59:250-261.
-
(2015)
Mol. Nutr. Food Res.
, vol.59
, pp. 250-261
-
-
Wang, P.1
Phan, T.2
Gordon, D.3
Chung, S.4
Henning, S.M.5
Vadgama, J.V.6
-
24
-
-
32944457064
-
Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation
-
Awale S, Lu J, Kalauni SK, Kurashima Y, Tezuka Y, Kadota S, Esumi H. Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation. Cancer Res. 2006;66:1751-1757.
-
(2006)
Cancer Res.
, vol.66
, pp. 1751-1757
-
-
Awale, S.1
Lu, J.2
Kalauni, S.K.3
Kurashima, Y.4
Tezuka, Y.5
Kadota, S.6
Esumi, H.7
-
25
-
-
38349107623
-
The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells
-
Longo PG, Laurenti L, Gobessi S, Sica S, Leone G, Efremov DG. The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells. Blood 2008;111:846-855.
-
(2008)
Blood
, vol.111
, pp. 846-855
-
-
Longo, P.G.1
Laurenti, L.2
Gobessi, S.3
Sica, S.4
Leone, G.5
Efremov, D.G.6
-
26
-
-
77951623315
-
Regulation of survivin by PI3K/Akt/p70S6K1 pathway
-
Zhao P, Meng Q, Liu LZ, You YP, Liu N, Jiang BH. Regulation of survivin by PI3K/Akt/p70S6K1 pathway. Biochem. Biophys. Res. Commun. 2010;395:219-224.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.395
, pp. 219-224
-
-
Zhao, P.1
Meng, Q.2
Liu, L.Z.3
You, Y.P.4
Liu, N.5
Jiang, B.H.6
|