메뉴 건너뛰기




Volumn 16, Issue 11, 2015, Pages 1137-1154

Endocytosis of Ubiquitylation-Deficient EGFR Mutants via Clathrin-Coated Pits is Mediated by Ubiquitylation

Author keywords

Clathrin; EGF; Endocytosis; Ubiquitin

Indexed keywords

CBL PROTEIN; CLATHRIN; CLATHRIN COATED PIT PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; UBIQUITIN;

EID: 84944151542     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12314     Document Type: Article
Times cited : (31)

References (50)
  • 2
    • 77953896432 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Lemmon MA, Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2010;141:1117-1134.
    • (2010) Cell , vol.141 , pp. 1117-1134
    • Lemmon, M.A.1    Schlessinger, J.2
  • 3
    • 62649159446 scopus 로고    scopus 로고
    • Endocytosis and intracellular trafficking of ErbBs
    • Sorkin A, Goh LK. Endocytosis and intracellular trafficking of ErbBs. Exp Cell Res 2009;315:683-696.
    • (2009) Exp Cell Res , vol.315 , pp. 683-696
    • Sorkin, A.1    Goh, L.K.2
  • 5
    • 0037075547 scopus 로고    scopus 로고
    • Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
    • Soubeyran P, Kowanetz K, Szymkiewicz I, Langdon WY, Dikic I. Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature 2002;416:183-187.
    • (2002) Nature , vol.416 , pp. 183-187
    • Soubeyran, P.1    Kowanetz, K.2    Szymkiewicz, I.3    Langdon, W.Y.4    Dikic, I.5
  • 8
    • 84924898139 scopus 로고    scopus 로고
    • Dimerization drives EGFR endocytosis through two sets of compatible endocytic codes
    • Wang Q, Chen X, Wang Z. Dimerization drives EGFR endocytosis through two sets of compatible endocytic codes. J Cell Sci 2015;128:935-950.
    • (2015) J Cell Sci , vol.128 , pp. 935-950
    • Wang, Q.1    Chen, X.2    Wang, Z.3
  • 10
    • 0018749910 scopus 로고
    • Epidermal growth factor (urogastrone) in human tissues
    • Hirata Y, Orth DN. Epidermal growth factor (urogastrone) in human tissues. J Clin Endocrinol Metab 1979;48:667-672.
    • (1979) J Clin Endocrinol Metab , vol.48 , pp. 667-672
    • Hirata, Y.1    Orth, D.N.2
  • 11
    • 65249119387 scopus 로고    scopus 로고
    • Dose-dependent increases in circulating TGF-alpha and other EGFR ligands act as pharmacodynamic markers for optimal biological dosing of cetuximab and are tumor independent
    • Mutsaers AJ, Francia G, Man S, Lee CR, Ebos JM, Wu Y, Witte L, Berry S, Moore M, Kerbel RS. Dose-dependent increases in circulating TGF-alpha and other EGFR ligands act as pharmacodynamic markers for optimal biological dosing of cetuximab and are tumor independent. Clin Cancer Res 2009;15:2397-2405.
    • (2009) Clin Cancer Res , vol.15 , pp. 2397-2405
    • Mutsaers, A.J.1    Francia, G.2    Man, S.3    Lee, C.R.4    Ebos, J.M.5    Wu, Y.6    Witte, L.7    Berry, S.8    Moore, M.9    Kerbel, R.S.10
  • 12
    • 0020579520 scopus 로고
    • Human plasma epidermal growth factor/beta-urogastrone is associated with blood platelets
    • Oka Y, Orth DN. Human plasma epidermal growth factor/beta-urogastrone is associated with blood platelets. J Clin Invest 1983;72:249-259.
    • (1983) J Clin Invest , vol.72 , pp. 249-259
    • Oka, Y.1    Orth, D.N.2
  • 15
    • 77953167957 scopus 로고    scopus 로고
    • Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor
    • Goh LK, Huang F, Kim W, Gygi S, Sorkin A. Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor. J Cell Biol 2010;189:871-883.
    • (2010) J Cell Biol , vol.189 , pp. 871-883
    • Goh, L.K.1    Huang, F.2    Kim, W.3    Gygi, S.4    Sorkin, A.5
  • 17
    • 0036469898 scopus 로고    scopus 로고
    • A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling
    • Waterman H, Katz M, Rubin C, Shtiegman K, Lavi S, Elson A, Jovin T, Yarden Y. A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling. EMBO J 2002;21:303-313.
    • (2002) EMBO J , vol.21 , pp. 303-313
    • Waterman, H.1    Katz, M.2    Rubin, C.3    Shtiegman, K.4    Lavi, S.5    Elson, A.6    Jovin, T.7    Yarden, Y.8
  • 18
    • 0037339887 scopus 로고    scopus 로고
    • Grb2 regulates internalization of EGF receptors through clathrin-coated pits
    • Jiang X, Huang F, Marusyk A, Sorkin A. Grb2 regulates internalization of EGF receptors through clathrin-coated pits. Mol Biol Cell 2003;14:858-870.
    • (2003) Mol Biol Cell , vol.14 , pp. 858-870
    • Jiang, X.1    Huang, F.2    Marusyk, A.3    Sorkin, A.4
  • 19
    • 62649146531 scopus 로고    scopus 로고
    • ERBBs in the gastrointestinal tract: recent progress and new perspectives
    • Fiske WH, Threadgill D, Coffey RJ. ERBBs in the gastrointestinal tract: recent progress and new perspectives. Exp Cell Res 2009;315:583-601.
    • (2009) Exp Cell Res , vol.315 , pp. 583-601
    • Fiske, W.H.1    Threadgill, D.2    Coffey, R.J.3
  • 20
    • 1942469322 scopus 로고    scopus 로고
    • Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference
    • Huang F, Khvorova A, Marshall W, Sorkin A. Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J Biol Chem 2004;279:16657-16661.
    • (2004) J Biol Chem , vol.279 , pp. 16657-16661
    • Huang, F.1    Khvorova, A.2    Marshall, W.3    Sorkin, A.4
  • 21
    • 33644852909 scopus 로고    scopus 로고
    • Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain
    • Huang F, Kirkpatrick D, Jiang X, Gygi S, Sorkin A. Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Mol Cell 2006;21:737-748.
    • (2006) Mol Cell , vol.21 , pp. 737-748
    • Huang, F.1    Kirkpatrick, D.2    Jiang, X.3    Gygi, S.4    Sorkin, A.5
  • 22
    • 84860513160 scopus 로고    scopus 로고
    • Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning
    • Umasankar PK, Sanker S, Thieman JR, Chakraborty S, Wendland B, Tsang M, Traub LM. Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning. Nat Cell Biol 2012;14:488-501.
    • (2012) Nat Cell Biol , vol.14 , pp. 488-501
    • Umasankar, P.K.1    Sanker, S.2    Thieman, J.R.3    Chakraborty, S.4    Wendland, B.5    Tsang, M.6    Traub, L.M.7
  • 23
    • 54249151578 scopus 로고    scopus 로고
    • Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
    • Umebayashi K, Stenmark H, Yoshimori T. Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation. Mol Biol Cell 2008;19:3454-3462.
    • (2008) Mol Biol Cell , vol.19 , pp. 3454-3462
    • Umebayashi, K.1    Stenmark, H.2    Yoshimori, T.3
  • 24
    • 79953129607 scopus 로고    scopus 로고
    • Protein kinase C-dependent ubiquitination and clathrin-mediated endocytosis of the cationic amino acid transporter CAT-1
    • Vina-Vilaseca A, Bender-Sigel J, Sorkina T, Closs EI, Sorkin A. Protein kinase C-dependent ubiquitination and clathrin-mediated endocytosis of the cationic amino acid transporter CAT-1. J Biol Chem 2011;286:8697-8706.
    • (2011) J Biol Chem , vol.286 , pp. 8697-8706
    • Vina-Vilaseca, A.1    Bender-Sigel, J.2    Sorkina, T.3    Closs, E.I.4    Sorkin, A.5
  • 25
    • 33748146552 scopus 로고    scopus 로고
    • RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis
    • Sorkina T, Miranda M, Dionne KR, Hoover BR, Zahniser NR, Sorkin A. RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis. J Neurosci 2006;26:8195-8205.
    • (2006) J Neurosci , vol.26 , pp. 8195-8205
    • Sorkina, T.1    Miranda, M.2    Dionne, K.R.3    Hoover, B.R.4    Zahniser, N.R.5    Sorkin, A.6
  • 26
    • 70450225242 scopus 로고    scopus 로고
    • Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor
    • Liu NS, Loo LS, Loh E, Seet LF, Hong W. Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor. EMBO J 2009;28:3485-3499.
    • (2009) EMBO J , vol.28 , pp. 3485-3499
    • Liu, N.S.1    Loo, L.S.2    Loh, E.3    Seet, L.F.4    Hong, W.5
  • 27
    • 14844334946 scopus 로고    scopus 로고
    • Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis
    • Huang F, Sorkin A. Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis. Mol Biol Cell 2005;16:1268-1281.
    • (2005) Mol Biol Cell , vol.16 , pp. 1268-1281
    • Huang, F.1    Sorkin, A.2
  • 28
    • 77951221830 scopus 로고    scopus 로고
    • Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes
    • Vina-Vilaseca A, Sorkin A. Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes. J Biol Chem 2010;285:7645-7656.
    • (2010) J Biol Chem , vol.285 , pp. 7645-7656
    • Vina-Vilaseca, A.1    Sorkin, A.2
  • 34
    • 36749036679 scopus 로고    scopus 로고
    • EGF receptor ubiquitination is not necessary for its internalization
    • Huang F, Goh LK, Sorkin A. EGF receptor ubiquitination is not necessary for its internalization. Proc Natl Acad Sci U S A 2007;104:16904-16909.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 16904-16909
    • Huang, F.1    Goh, L.K.2    Sorkin, A.3
  • 35
    • 0242290315 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the beta2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking
    • Huang F, Jiang X, Sorkin A. Tyrosine phosphorylation of the beta2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking. J Biol Chem 2003;278:43411-43417.
    • (2003) J Biol Chem , vol.278 , pp. 43411-43417
    • Huang, F.1    Jiang, X.2    Sorkin, A.3
  • 36
    • 0037178805 scopus 로고    scopus 로고
    • Effect of tyrosine kinase inhibitors on clathrin-coated pit recruitment and internalization of epidermal growth factor receptor
    • Sorkina T, Huang F, Beguinot L, Sorkin A. Effect of tyrosine kinase inhibitors on clathrin-coated pit recruitment and internalization of epidermal growth factor receptor. J Biol Chem 2002;277:27433-27441.
    • (2002) J Biol Chem , vol.277 , pp. 27433-27441
    • Sorkina, T.1    Huang, F.2    Beguinot, L.3    Sorkin, A.4
  • 37
    • 84894680440 scopus 로고    scopus 로고
    • Cell adhesion defines the topology of endocytosis and signaling
    • Grossier JP, Xouri G, Goud B, Schauer K. Cell adhesion defines the topology of endocytosis and signaling. EMBO J 2014;33:35-45.
    • (2014) EMBO J , vol.33 , pp. 35-45
    • Grossier, J.P.1    Xouri, G.2    Goud, B.3    Schauer, K.4
  • 42
    • 79953718772 scopus 로고    scopus 로고
    • A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis
    • Taylor MJ, Perrais D, Merrifield CJ. A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis. PLoS Biol 2011;9:e1000604.
    • (2011) PLoS Biol , vol.9 , pp. e1000604
    • Taylor, M.J.1    Perrais, D.2    Merrifield, C.J.3
  • 43
    • 84878704042 scopus 로고    scopus 로고
    • Divergent modes for cargo-mediated control of clathrin-coated pit dynamics
    • S1721-S1712.
    • Soohoo AL, Puthenveedu MA. Divergent modes for cargo-mediated control of clathrin-coated pit dynamics. Mol Biol Cell 2013;24:1725-1734S1721-S1712.
    • (2013) Mol Biol Cell , vol.24 , pp. 1725-1734
    • Soohoo, A.L.1    Puthenveedu, M.A.2
  • 44
  • 45
    • 84925387525 scopus 로고    scopus 로고
    • Tagging endogenous loci for live-cell fluorescence imaging and molecule counting using ZFNs, TALENs, and Cas9
    • Dambournet D, Hong SH, Grassart A, Drubin DG. Tagging endogenous loci for live-cell fluorescence imaging and molecule counting using ZFNs, TALENs, and Cas9. Methods Enzymol 2014;546:139-160.
    • (2014) Methods Enzymol , vol.546 , pp. 139-160
    • Dambournet, D.1    Hong, S.H.2    Grassart, A.3    Drubin, D.G.4
  • 46
    • 50149096579 scopus 로고    scopus 로고
    • Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virus
    • Chen C, Zhuang X. Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virus. Proc Natl Acad Sci U S A 2008;105:11790-11795.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 11790-11795
    • Chen, C.1    Zhuang, X.2
  • 47
    • 84859175662 scopus 로고    scopus 로고
    • Membrane fission is promoted by insertion of amphipathic helices and is restricted by crescent BAR domains
    • Boucrot E, Pick A, Camdere G, Liska N, Evergren E, McMahon HT, Kozlov MM. Membrane fission is promoted by insertion of amphipathic helices and is restricted by crescent BAR domains. Cell 2012;149:124-136.
    • (2012) Cell , vol.149 , pp. 124-136
    • Boucrot, E.1    Pick, A.2    Camdere, G.3    Liska, N.4    Evergren, E.5    McMahon, H.T.6    Kozlov, M.M.7
  • 48
    • 77949645984 scopus 로고    scopus 로고
    • Quantitative analysis of endocytosis and turnover of epidermal growth factor (EGF) and EGF receptor
    • Chapter 15: Unit 15 14
    • Sorkin A, Duex JE. Quantitative analysis of endocytosis and turnover of epidermal growth factor (EGF) and EGF receptor. Curr Protoc Cell Biol 2010;Chapter 15:Unit 15 14.
    • (2010) Curr Protoc Cell Biol
    • Sorkin, A.1    Duex, J.E.2
  • 49
    • 84877333864 scopus 로고    scopus 로고
    • Improved precision of proteomic measurements in immunoprecipitation based purifications using relative quantitation
    • Rogstad SM, Sorkina T, Sorkin A, Wu CC. Improved precision of proteomic measurements in immunoprecipitation based purifications using relative quantitation. Anal Chem 2013;85:4301-4306.
    • (2013) Anal Chem , vol.85 , pp. 4301-4306
    • Rogstad, S.M.1    Sorkina, T.2    Sorkin, A.3    Wu, C.C.4
  • 50
    • 84892496733 scopus 로고    scopus 로고
    • Live-cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosis
    • Fortian A, Sorkin A. Live-cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosis. J Cell Sci 2014;127:432-444.
    • (2014) J Cell Sci , vol.127 , pp. 432-444
    • Fortian, A.1    Sorkin, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.