Endocytosis of Ubiquitylation-Deficient EGFR Mutants via Clathrin-Coated Pits is Mediated by Ubiquitylation

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Volumn 16, Issue 11, 2015, Pages 1137-1154

  Fortian, Arola ^a   Dionne, Lai K ^b   Hong, Sun H ^c   Kim, Woong ^d   Gygi, Steven P ^d   Watkins, Simon C ^a   Sorkin, Alexander ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Clathrin; EGF; Endocytosis; Ubiquitin

Indexed keywords

CBL PROTEIN; CLATHRIN; CLATHRIN COATED PIT PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; UBIQUITIN;

ACETYLATION; ADENOCARCINOMA; ARTICLE; BINDING SITE; CONJUGATION; CONTROLLED STUDY; DUODENUM CARCINOMA; ENDOCYTOSIS; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTERNALIZATION; MASS SPECTROMETRY; MUTANT; PRIORITY JOURNAL; PROTEIN DEPLETION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UBIQUITINATION; COATED PIT; METABOLISM; PHYSIOLOGY; PROTEIN PROCESSING;

BINDING SITES; CLATHRIN; COATED PITS, CELL-MEMBRANE; ENDOCYTOSIS; HUMANS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, EPIDERMAL GROWTH FACTOR; UBIQUITIN; UBIQUITINATION;

EID: 84944151542     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12314     Document Type: Article

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