메뉴 건너뛰기




Volumn 94, Issue 40, 2015, Pages

NF-κB expression and outcomes in solid tumors: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR MARKER;

EID: 84944057765     PISSN: 00257974     EISSN: 15365964     Source Type: Journal    
DOI: 10.1097/MD.0000000000001687     Document Type: Review
Times cited : (89)

References (69)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-674.
    • (2011) Cell. , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 84908161000 scopus 로고    scopus 로고
    • Revisiting STAT3 signalling in cancer: New and unexpected biological functions
    • Yu H, Lee H, Herrmann A, et al. Revisiting STAT3 signalling in cancer: new and unexpected biological functions. Nat Rev Cancer. 2014;14:736-746.
    • (2014) Nat Rev Cancer. , vol.14 , pp. 736-746
    • Yu, H.1    Lee, H.2    Herrmann, A.3
  • 3
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-kappaB as the matchmaker
    • Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat Immunol. 2011;12:715-723.
    • (2011) Nat Immunol. , vol.12 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 4
    • 77549083560 scopus 로고    scopus 로고
    • Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer
    • Grivennikov SI, Karin M. Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer. Cytokine Growth Factor Rev. 2010;21:11-19.
    • (2010) Cytokine Growth Factor Rev. , vol.21 , pp. 11-19
    • Grivennikov, S.I.1    Karin, M.2
  • 5
    • 0022930702 scopus 로고
    • Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
    • Sen R, Baltimore D. Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism. Cell. 1986;47:921-928.
    • (1986) Cell. , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 6
    • 0027436597 scopus 로고
    • Proposed NF-kappa B/I kappa B family nomenclature
    • Nabel GJ, Verma IM. Proposed NF-kappa B/I kappa B family nomenclature. Genes Dev. 1993;7:2063.
    • (1993) Genes Dev. , vol.7 , pp. 2063
    • Nabel, G.J.1    Verma, I.M.2
  • 7
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, et al. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer. 2002;2:301-310.
    • (2002) Nat Rev Cancer. , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3
  • 8
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappaB puzzle
    • Ghosh S, Karin M. Missing pieces in the NF-kappaB puzzle. Cell. 2002;109(Suppl):S81-S96.
    • (2002) Cell. , vol.109 , pp. S81-S96
    • Ghosh, S.1    Karin, M.2
  • 9
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death
    • Karin M, Lin A. NF-kappaB at the crossroads of life and death. Nat Immunol. 2002;3:221-227.
    • (2002) Nat Immunol. , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 10
    • 33645983982 scopus 로고    scopus 로고
    • The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease
    • Papa S, Bubici C, Zazzeroni F, et al. The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease. Cell Death Differ. 2006;13: 712-729.
    • (2006) Cell Death Differ. , vol.13 , pp. 712-729
    • Papa, S.1    Bubici, C.2    Zazzeroni, F.3
  • 11
    • 0025975795 scopus 로고
    • DNA binding and i kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide
    • Nolan GP, Ghosh S, Liou HC, et al. DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide. Cell. 1991;64:961-969.
    • (1991) Cell. , vol.64 , pp. 961-969
    • Nolan, G.P.1    Ghosh, S.2    Liou, H.C.3
  • 12
    • 0035905313 scopus 로고    scopus 로고
    • Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells
    • Davis RE, Brown KD, Siebenlist U, et al. Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells. J Exp Med. 2001;194:1861-1874.
    • (2001) J Exp Med. , vol.194 , pp. 1861-1874
    • Davis, R.E.1    Brown, K.D.2    Siebenlist, U.3
  • 13
    • 0037972018 scopus 로고    scopus 로고
    • Increased expression of RelA/nuclear factor-kappa B protein correlates with colorectal tumorigenesis
    • Yu HG, Yu LL, Yang Y, et al. Increased expression of RelA/nuclear factor-kappa B protein correlates with colorectal tumorigenesis. Oncology. 2003;65:37-45.
    • (2003) Oncology. , vol.65 , pp. 37-45
    • Yu, H.G.1    Yu, L.L.2    Yang, Y.3
  • 14
    • 17644400134 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer
    • Lee BL, Lee HS, Jung J, et al. Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer. Clin Cancer Res. 2005;11:2518-2525.
    • (2005) Clin Cancer Res. , vol.11 , pp. 2518-2525
    • Lee, B.L.1    Lee, H.S.2    Jung, J.3
  • 15
    • 33845217696 scopus 로고    scopus 로고
    • Pretherapy nuclear factor-kappaB status, chemoradiation resistance, and metastatic progression in esophageal carcinoma
    • Izzo JG, Correa AM, Wu TT, et al. Pretherapy nuclear factor-kappaB status, chemoradiation resistance, and metastatic progression in esophageal carcinoma. Mol Cancer Ther. 2006;5:2844-2850.
    • (2006) Mol Cancer Ther. , vol.5 , pp. 2844-2850
    • Izzo, J.G.1    Correa, A.M.2    Wu, T.T.3
  • 16
    • 22144449607 scopus 로고    scopus 로고
    • Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model
    • Shukla S, Maclennan GT, Marengo SR, et al. Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model. Prostate. 2005;64:224-239.
    • (2005) Prostate. , vol.64 , pp. 224-239
    • Shukla, S.1    Maclennan, G.T.2    Marengo, S.R.3
  • 17
    • 0035963273 scopus 로고    scopus 로고
    • Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells
    • Oya M, Ohtsubo M, Takayanagi A, et al. Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells. Oncogene. 2001;20:3888-3896.
    • (2001) Oncogene. , vol.20 , pp. 3888-3896
    • Oya, M.1    Ohtsubo, M.2    Takayanagi, A.3
  • 18
    • 77954297744 scopus 로고    scopus 로고
    • Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancer
    • Annunziata CM, Stavnes HT, Kleinberg L, et al. Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancer. Cancer. 2010;116:3276-3284.
    • (2010) Cancer. , vol.116 , pp. 3276-3284
    • Annunziata, C.M.1    Stavnes, H.T.2    Kleinberg, L.3
  • 19
    • 73349106810 scopus 로고    scopus 로고
    • Association of constitutive nuclear factor-kappaB activation with aggressive aspects and poor prognosis in cervical cancer
    • Li J, Jia H, Xie L, et al. Association of constitutive nuclear factor-kappaB activation with aggressive aspects and poor prognosis in cervical cancer. Int J Gynecol Cancer. 2009;19:1421-1426.
    • (2009) Int J Gynecol Cancer. , vol.19 , pp. 1421-1426
    • Li, J.1    Jia, H.2    Xie, L.3
  • 20
    • 34547686047 scopus 로고    scopus 로고
    • Constitutive and inducible nuclear factor-kappaB in immortalized normal human bronchial epithelial and non-small cell lung cancer cell lines
    • Baby J, Pickering BF, Vashisht Gopal YN, et al. Constitutive and inducible nuclear factor-kappaB in immortalized normal human bronchial epithelial and non-small cell lung cancer cell lines. Cancer Lett. 2007;255:85-94.
    • (2007) Cancer Lett. , vol.255 , pp. 85-94
    • Baby, J.1    Pickering, B.F.2    Vashisht Gopal, Y.N.3
  • 21
    • 33847394078 scopus 로고    scopus 로고
    • Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma
    • Jackson-Bernitsas DG, Ichikawa H, Takada Y, et al. Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma. Oncogene. 2007;26:1385-1397.
    • (2007) Oncogene. , vol.26 , pp. 1385-1397
    • Jackson-Bernitsas, D.G.1    Ichikawa, H.2    Takada, Y.3
  • 22
    • 19944426112 scopus 로고    scopus 로고
    • Oncogenic and anti-apoptotic activity of NF-kappa B in human thyroid carcinomas
    • Pacifico F, Mauro C, Barone C, et al. Oncogenic and anti-apoptotic activity of NF-kappa B in human thyroid carcinomas. J Biol Chem. 2004;279:54610-54619.
    • (2004) J Biol Chem. , vol.279 , pp. 54610-54619
    • Pacifico, F.1    Mauro, C.2    Barone, C.3
  • 23
    • 79953782203 scopus 로고    scopus 로고
    • NF-kappaB addiction and its role in cancer: 'One size does not fit all'
    • Chaturvedi MM, Sung B, Yadav VR, et al. NF-kappaB addiction and its role in cancer: 'one size does not fit all'. Oncogene. 2011;30:1615-1630.
    • (2011) Oncogene. , vol.30 , pp. 1615-1630
    • Chaturvedi, M.M.1    Sung, B.2    Yadav, V.R.3
  • 24
    • 68049137869 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration
    • Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6:e1000100.
    • (2009) PLoS Med. , vol.6 , pp. e1000100
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3
  • 25
    • 77957661914 scopus 로고    scopus 로고
    • Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses
    • Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25:603-605.
    • (2010) Eur J Epidemiol. , vol.25 , pp. 603-605
    • Stang, A.1
  • 27
    • 84861344780 scopus 로고    scopus 로고
    • Nuclear factor-kappaB predicts outcome in locally advanced rectal cancer patients receiving neoadjuvant radio-chemotherapy
    • Berardi R, Maccaroni E, Mandolesi A, et al. Nuclear factor-kappaB predicts outcome in locally advanced rectal cancer patients receiving neoadjuvant radio-chemotherapy. Dig Liver Dis. 2012;44:617-622.
    • (2012) Dig Liver Dis. , vol.44 , pp. 617-622
    • Berardi, R.1    Maccaroni, E.2    Mandolesi, A.3
  • 28
    • 80052446486 scopus 로고    scopus 로고
    • Notch1 expression, which is related to p65 Status, is an independent predictor of prognosis in colorectal cancer
    • Chu D, Zhou Y, Zhang Z, et al. Notch1 expression, which is related to p65 Status, is an independent predictor of prognosis in colorectal cancer. Clin Cancer Res. 2011;17:5686-5694.
    • (2011) Clin Cancer Res. , vol.17 , pp. 5686-5694
    • Chu, D.1    Zhou, Y.2    Zhang, Z.3
  • 29
    • 77954157682 scopus 로고    scopus 로고
    • Clinicopathological significance of nuclear factor-kappa B HIF-1 alpha and vascular endothelial growth factor expression in stage III colorectal cancer
    • Kwon HC, Kim SH, Oh SY, et al. Clinicopathological significance of nuclear factor-kappa B, HIF-1 alpha, and vascular endothelial growth factor expression in stage III colorectal cancer. Cancer Sci. 2010;101:1557-1561.
    • (2010) Cancer Sci. , vol.101 , pp. 1557-1561
    • Kwon, H.C.1    Kim, S.H.2    Oh, S.Y.3
  • 30
    • 84862986139 scopus 로고    scopus 로고
    • NF-kappaB p65 phosphory-lated at serine-536 is an independent prognostic factor in Swedish colorectal cancer patients
    • Lewander A, Gao J, Carstensen J, et al. NF-kappaB p65 phosphory-lated at serine-536 is an independent prognostic factor in Swedish colorectal cancer patients. Int J Colorectal Dis. 2012;27:447-452.
    • (2012) Int J Colorectal Dis. , vol.27 , pp. 447-452
    • Lewander, A.1    Gao, J.2    Carstensen, J.3
  • 31
    • 84858233588 scopus 로고    scopus 로고
    • NF-kappaB activity is downregulated by KRAS knockdown in SW620 cells via the RAS-ERK-IkappaBal-pha pathway
    • Lin G, Tang Z, Ye YB, et al. NF-kappaB activity is downregulated by KRAS knockdown in SW620 cells via the RAS-ERK-IkappaBal-pha pathway. Oncol Rep. 2012;27:1527-1534.
    • (2012) Oncol Rep. , vol.27 , pp. 1527-1534
    • Lin, G.1    Tang, Z.2    Ye, Y.B.3
  • 32
    • 79957556270 scopus 로고    scopus 로고
    • Nuclear factor kappa-light chain-enhancer of activated B cells is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiotheraphy
    • O'Neil BH, Funkhouser WK, Calvo BF, et al. Nuclear factor kappa-light chain-enhancer of activated B cells is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiotheraphy. Int J Radiat Oncol Biol Phys. 2011;80:705-711.
    • (2011) Int J Radiat Oncol Biol Phys. , vol.80 , pp. 705-711
    • O'Neil, B.H.1    Funkhouser, W.K.2    Calvo, B.F.3
  • 33
    • 64049092259 scopus 로고    scopus 로고
    • Reduced beta-catenin and peroxisome proliferator-activated receptor-gamma expression levels are associated with colorectal cancer metastatic progression: Correlation with tumor-associated macrophages, cyclooxygenase 2, and patient outcome
    • Pancione M, Forte N, Sabatino L, et al. Reduced beta-catenin and peroxisome proliferator-activated receptor-gamma expression levels are associated with colorectal cancer metastatic progression: correlation with tumor-associated macrophages, cyclooxygenase 2, and patient outcome. Hum Pathol. 2009;40:714-725.
    • (2009) Hum Pathol. , vol.40 , pp. 714-725
    • Pancione, M.1    Forte, N.2    Sabatino, L.3
  • 34
    • 44449089360 scopus 로고    scopus 로고
    • Dissociated invasively growing cancer cells with NF-kappaB/p65 positivity after radiotherapy: A new marker for worse clinical outcome in rectal cancer? Preliminary data
    • Voboril R, Voborilova J, Rychterova V, et al. Dissociated invasively growing cancer cells with NF-kappaB/p65 positivity after radiotherapy: a new marker for worse clinical outcome in rectal cancer? Preliminary data. Clin Exp Metastasis. 2008;25:491-496.
    • (2008) Clin Exp Metastasis. , vol.25 , pp. 491-496
    • Voboril, R.1    Voborilova, J.2    Rychterova, V.3
  • 35
    • 1642334954 scopus 로고    scopus 로고
    • NF-kappaB activation in esophageal adenocarcinoma: Relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiother-apy
    • Abdel-Latif MM, O'Riordan J, Windle HJ, et al. NF-kappaB activation in esophageal adenocarcinoma: relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiother-apy. Ann Surg. 2004;239:491-500.
    • (2004) Ann Surg. , vol.239 , pp. 491-500
    • Abdel-Latif, M.M.1    O'Riordan, J.2    Windle, H.J.3
  • 36
    • 84868494287 scopus 로고    scopus 로고
    • Immunohistochemical study of nuclear factor-kappaB expression in esophageal squamous cell carcinoma: Prognostic significance and sensitivity to treatment with 5-FU
    • Hatata T, Higaki K, Tatebe S, et al. Immunohistochemical study of nuclear factor-kappaB expression in esophageal squamous cell carcinoma: prognostic significance and sensitivity to treatment with 5-FU. Dis Esophagus. 2012;25:716-722.
    • (2012) Dis Esophagus. , vol.25 , pp. 716-722
    • Hatata, T.1    Higaki, K.2    Tatebe, S.3
  • 37
    • 33644853585 scopus 로고    scopus 로고
    • Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma
    • Izzo JG, Malhotra U, Wu TT, et al. Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma. J Clin Oncol. 2006;24:748-754.
    • (2006) J Clin Oncol. , vol.24 , pp. 748-754
    • Izzo, J.G.1    Malhotra, U.2    Wu, T.T.3
  • 38
    • 34250832837 scopus 로고    scopus 로고
    • Clinical biology of esophageal adenocarcinoma after surgery is influenced by nuclear factor-kappaB expression
    • Izzo JG, Malhotra U, Wu TT, et al. Clinical biology of esophageal adenocarcinoma after surgery is influenced by nuclear factor-kappaB expression. Cancer Epidemiol Biomarkers Prev. 2007;16:1200-1205.
    • (2007) Cancer Epidemiol Biomarkers Prev. , vol.16 , pp. 1200-1205
    • Izzo, J.G.1    Malhotra, U.2    Wu, T.T.3
  • 39
    • 84867723234 scopus 로고    scopus 로고
    • Clinicopathologic significance of expression of nuclear factor-kappaB RelA and its target gene products in gastric cancer patients
    • Kwon HC, Kim SH, Oh SY, et al. Clinicopathologic significance of expression of nuclear factor-kappaB RelA and its target gene products in gastric cancer patients. World J Gastroenterol. 2012;18:4744-4750.
    • (2012) World J Gastroenterol. , vol.18 , pp. 4744-4750
    • Kwon, H.C.1    Kim, S.H.2    Oh, S.Y.3
  • 40
    • 34247602606 scopus 로고    scopus 로고
    • Expression of nuclear factor kappaB in human gastric carcinoma: Relationship with i kappaB a and prognostic significance
    • Levidou G, Korkolopoulou P, Nikiteas N, et al. Expression of nuclear factor kappaB in human gastric carcinoma: relationship with I kappaB a and prognostic significance. Virchows Arch. 2007;450:519-527.
    • (2007) Virchows Arch. , vol.450 , pp. 519-527
    • Levidou, G.1    Korkolopoulou, P.2    Nikiteas, N.3
  • 41
    • 84922060849 scopus 로고    scopus 로고
    • Clinicopathologic significance of nuclear factor-kappaB and vascular endothelial growth factor expression in advanced gastric cancer patients
    • Park KW, Kim SJ, Oh SY. Clinicopathologic significance of nuclear factor-kappaB and vascular endothelial growth factor expression in advanced gastric cancer patients. Oncol Res Treat. 2014;37:183-190.
    • (2014) Oncol Res Treat. , vol.37 , pp. 183-190
    • Park, K.W.1    Kim, S.J.2    Oh, S.Y.3
  • 42
    • 2442630587 scopus 로고    scopus 로고
    • Nuclear factor-kappaB p65 is a prognostic indicator in gastric carcinoma
    • Yamanaka N, Sasaki N, Tasaki A, et al. Nuclear factor-kappaB p65 is a prognostic indicator in gastric carcinoma. Anticancer Res. 2004;24:1071-1075.
    • (2004) Anticancer Res. , vol.24 , pp. 1071-1075
    • Yamanaka, N.1    Sasaki, N.2    Tasaki, A.3
  • 43
    • 77951717987 scopus 로고    scopus 로고
    • Expression of classical NF-kappaB pathway effectors in human ovarian carcinoma
    • Darb-Esfahani S, Sinn BV, Weichert W, et al. Expression of classical NF-kappaB pathway effectors in human ovarian carcinoma. Histopathology. 2010;56:727-739.
    • (2010) Histopathology. , vol.56 , pp. 727-739
    • Darb-Esfahani, S.1    Sinn, B.V.2    Weichert, W.3
  • 44
    • 56049094836 scopus 로고    scopus 로고
    • Increased staining for phosphorylated AKT and nuclear factor-kappaB p65 and their relationship with prognosis in epithelial ovarian cancer
    • Guo RX, Qiao YH, Zhou Y, et al. Increased staining for phosphorylated AKT and nuclear factor-kappaB p65 and their relationship with prognosis in epithelial ovarian cancer. Pathol Int. 2008;58:749-756.
    • (2008) Pathol Int. , vol.58 , pp. 749-756
    • Guo, R.X.1    Qiao, Y.H.2    Zhou, Y.3
  • 45
    • 67349160447 scopus 로고    scopus 로고
    • Cleaved caspase-3 and nuclear factor-kappaB p65 are prognostic factors in metastatic serous ovarian carcinoma
    • Kleinberg L, Dong HP, Holth A, et al. Cleaved caspase-3 and nuclear factor-kappaB p65 are prognostic factors in metastatic serous ovarian carcinoma. Hum Pathol. 2009;40:795-806.
    • (2009) Hum Pathol. , vol.40 , pp. 795-806
    • Kleinberg, L.1    Dong, H.P.2    Holth, A.3
  • 46
    • 79954612742 scopus 로고    scopus 로고
    • The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer
    • Yang G, Xiao X, Rosen DG, et al. The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer. Clin Cancer Res. 2011;17:2181-2194.
    • (2011) Clin Cancer Res. , vol.17 , pp. 2181-2194
    • Yang, G.1    Xiao, X.2    Rosen, D.G.3
  • 47
    • 38949094884 scopus 로고    scopus 로고
    • Potential biomarkers involving IKK/RelA signal in early stage non-small cell lung cancer
    • Jin X, Wang Z, Qiu L, et al. Potential biomarkers involving IKK/RelA signal in early stage non-small cell lung cancer. Cancer Sci. 2008;99:582-589.
    • (2008) Cancer Sci. , vol.99 , pp. 582-589
    • Jin, X.1    Wang, Z.2    Qiu, L.3
  • 48
    • 84892841683 scopus 로고    scopus 로고
    • NF-kappaB protein expression associates with (18)F-FDG PET tumor uptake in non-small cell lung cancer: A radiogenomics validation study to understand tumor metabolism
    • Nair VS, Gevaert O, Davidzon G, et al. NF-kappaB protein expression associates with (18)F-FDG PET tumor uptake in non-small cell lung cancer: a radiogenomics validation study to understand tumor metabolism. Lung Cancer. 2014;83:189-196.
    • (2014) Lung Cancer. , vol.83 , pp. 189-196
    • Nair, V.S.1    Gevaert, O.2    Davidzon, G.3
  • 49
    • 36349003530 scopus 로고    scopus 로고
    • Combined prognostic value of both RelA and IkappaB-alpha expression in human non-small cell lung cancer
    • Zhang D, Jin X, Wang F, et al. Combined prognostic value of both RelA and IkappaB-alpha expression in human non-small cell lung cancer. Ann Surg Oncol. 2007;14:3581-3592.
    • (2007) Ann Surg Oncol. , vol.14 , pp. 3581-3592
    • Zhang, D.1    Jin, X.2    Wang, F.3
  • 50
    • 33745199608 scopus 로고    scopus 로고
    • Expression of nuclear factor-kappaB and its clinical significance in nonsmall-cell lung cancer
    • Zhang Z, Ma J, Li N, et al. Expression of nuclear factor-kappaB and its clinical significance in nonsmall-cell lung cancer. Ann Thorac Surg. 2006;82:243-248.
    • (2006) Ann Thorac Surg. , vol.82 , pp. 243-248
    • Zhang, Z.1    Ma, J.2    Li, N.3
  • 51
    • 84880442126 scopus 로고    scopus 로고
    • Constitutive activation of nuclear factor kappaB contributes to cystic fibrosis transmembrane conductance regulator expression and promotes human cervical cancer progression and poor prognosis
    • Wu Z, Peng X, Li J, et al. Constitutive activation of nuclear factor kappaB contributes to cystic fibrosis transmembrane conductance regulator expression and promotes human cervical cancer progression and poor prognosis. Int J Gynecol Cancer. 2013;23:906-915.
    • (2013) Int J Gynecol Cancer. , vol.23 , pp. 906-915
    • Wu, Z.1    Peng, X.2    Li, J.3
  • 52
    • 68249143415 scopus 로고    scopus 로고
    • Overexpression of mitogen-activated protein kinase kinase 4 and nuclear factor-kappaB in laryngeal squamous cell carcinoma: A potential indicator for poor prognosis
    • Huang C, Huang K, Wang C, et al. Overexpression of mitogen-activated protein kinase kinase 4 and nuclear factor-kappaB in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis. Oncol Rep. 2009;22:89-95.
    • (2009) Oncol Rep. , vol.22 , pp. 89-95
    • Huang, C.1    Huang, K.2    Wang, C.3
  • 53
    • 79960404953 scopus 로고    scopus 로고
    • Overexpression of Forkhead Box M1 transcription factor and nuclear factor-kappaB in laryngeal squamous cell carcinoma: A potential indicator for poor prognosis
    • Jiang LZ, Wang P, Deng B, et al. Overexpression of Forkhead Box M1 transcription factor and nuclear factor-kappaB in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis. Hum Pathol. 2011;42:1185-1193.
    • (2011) Hum Pathol. , vol.42 , pp. 1185-1193
    • Jiang, L.Z.1    Wang, P.2    Deng, B.3
  • 54
    • 84859590530 scopus 로고    scopus 로고
    • Id-1 and the p65 subunit of NF-kappaB promote migration of nasopharyngeal carcinoma cells and are correlated with poor prognosis
    • Sun W, Guo MM, Han P, et al. Id-1 and the p65 subunit of NF-kappaB promote migration of nasopharyngeal carcinoma cells and are correlated with poor prognosis. Carcinogenesis. 2012;33:810-817.
    • (2012) Carcinogenesis. , vol.33 , pp. 810-817
    • Sun, W.1    Guo, M.M.2    Han, P.3
  • 55
    • 84655165074 scopus 로고    scopus 로고
    • Association of nuclear factor kappaB expression with a poor outcome in nasopharyngeal carcinoma
    • Zhang Y, Lang JY, Liu L, et al. Association of nuclear factor kappaB expression with a poor outcome in nasopharyngeal carcinoma. Med Oncol. 2011;28:1338-1342.
    • (2011) Med Oncol. , vol.28 , pp. 1338-1342
    • Zhang, Y.1    Lang, J.Y.2    Liu, L.3
  • 56
    • 27144477363 scopus 로고    scopus 로고
    • Expressions of nuclear factor kappaB, inducible nitric oxide synthase, and vascular endothelial growth factor in adenoid cystic carcinoma of salivary glands: Correlations with the angiogenesis and clinical outcome
    • Zhang J, Peng B, Chen X. Expressions of nuclear factor kappaB, inducible nitric oxide synthase, and vascular endothelial growth factor in adenoid cystic carcinoma of salivary glands: correlations with the angiogenesis and clinical outcome. Clin Cancer Res. 2005;11:7334-7343.
    • (2005) Clin Cancer Res. , vol.11 , pp. 7334-7343
    • Zhang, J.1    Peng, B.2    Chen, X.3
  • 57
    • 47549114245 scopus 로고    scopus 로고
    • Expression of nuclear factor-kappaB in human astrocytomas: Relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvas-cular characteristics, and survival
    • Korkolopoulou P, Levidou G, Saetta AA, et al. Expression of nuclear factor-kappaB in human astrocytomas: relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvas-cular characteristics, and survival. Hum Pathol. 2008;39: 1143-1152.
    • (2008) Hum Pathol. , vol.39 , pp. 1143-1152
    • Korkolopoulou, P.1    Levidou, G.2    Saetta, A.A.3
  • 58
    • 40349096759 scopus 로고    scopus 로고
    • Heparanase expression in gallbladder carcinoma and its correlation to prognosis
    • Wu W, Pan C, Yu H, et al. Heparanase expression in gallbladder carcinoma and its correlation to prognosis. J Gastroenterol Hepatol. 2008;23:491-497.
    • (2008) J Gastroenterol Hepatol. , vol.23 , pp. 491-497
    • Wu, W.1    Pan, C.2    Yu, H.3
  • 59
    • 84879208087 scopus 로고    scopus 로고
    • Nuclear NF-kappaB expression correlates with outcome among patients with head and neck squamous cell carcinoma treated with primary chemor-adiation therapy
    • Balermpas P, Michel Y, Wagenblast J, et al. Nuclear NF-kappaB expression correlates with outcome among patients with head and neck squamous cell carcinoma treated with primary chemor-adiation therapy. Int J Radiat Oncol Biol Phys. 2013;86: 785-790.
    • (2013) Int J Radiat Oncol Biol Phys. , vol.86 , pp. 785-790
    • Balermpas, P.1    Michel, Y.2    Wagenblast, J.3
  • 60
    • 84896261889 scopus 로고    scopus 로고
    • Expression levels and significance of nuclear factor-kappaB and epidermal growth factor receptor in hepatolithiasis associated with intrahepatic cholangiocarcinoma
    • Zhou Q, Gong Y, Huang F, et al. Expression levels and significance of nuclear factor-kappaB and epidermal growth factor receptor in hepatolithiasis associated with intrahepatic cholangiocarcinoma. Dig Surg. 2013;30:309-316.
    • (2013) Dig Surg. , vol.30 , pp. 309-316
    • Zhou, Q.1    Gong, Y.2    Huang, F.3
  • 61
    • 79954418848 scopus 로고    scopus 로고
    • FAP-1 and NF-kappaB expressions in oral squamous cell carcinoma as potential markers for chemo-radio sensitivity and prognosis
    • Nariai Y, Mishima K, Yoshimura Y, et al. FAP-1 and NF-kappaB expressions in oral squamous cell carcinoma as potential markers for chemo-radio sensitivity and prognosis. Int J Oral Maxillofac Surg. 2011;40:419-426.
    • (2011) Int J Oral Maxillofac Surg. , vol.40 , pp. 419-426
    • Nariai, Y.1    Mishima, K.2    Yoshimura, Y.3
  • 62
    • 79960107662 scopus 로고    scopus 로고
    • Evaluation of nuclear factor kappaB and chemokine receptor CXCR4 co-expression in patients with prostate cancer in the Radiation Therapy Oncology Group (RTOG) 8610
    • Okera M, Bae K, Bernstein E, et al. Evaluation of nuclear factor kappaB and chemokine receptor CXCR4 co-expression in patients with prostate cancer in the Radiation Therapy Oncology Group (RTOG) 8610. BJU Int. 2011;108:E51-E58.
    • (2011) BJU Int. , vol.108 , pp. E51-E58
    • Okera, M.1    Bae, K.2    Bernstein, E.3
  • 63
    • 77957584996 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation predicts an unfavourable outcome in human upper urinary tract urothelial carcinoma
    • Yeh HC, Huang CH, Yang SF, et al. Nuclear factor-kappaB activation predicts an unfavourable outcome in human upper urinary tract urothelial carcinoma. BJU Int. 2010;106:1223-1229.
    • (2010) BJU Int. , vol.106 , pp. 1223-1229
    • Yeh, H.C.1    Huang, C.H.2    Yang, S.F.3
  • 64
    • 34547865350 scopus 로고    scopus 로고
    • High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis
    • Weichert W, Boehm M, Gekeler V, et al. High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis. Br J Cancer. 2007;97:523-530.
    • (2007) Br J Cancer. , vol.97 , pp. 523-530
    • Weichert, W.1    Boehm, M.2    Gekeler, V.3
  • 65
    • 68249087325 scopus 로고    scopus 로고
    • Differential protein immunoex-pression profiles in appendiceal mucinous neoplasms: A special reference to classification and predictive factors
    • Yoon SO, Kim BH, Lee HS, et al. Differential protein immunoex-pression profiles in appendiceal mucinous neoplasms: a special reference to classification and predictive factors. Mod Pathol. 2009;22:1102-1112.
    • (2009) Mod Pathol. , vol.22 , pp. 1102-1112
    • Yoon, S.O.1    Kim, B.H.2    Lee, H.S.3
  • 66
    • 84858718448 scopus 로고    scopus 로고
    • NF-kappaB and the link between inflammation and cancer
    • DiDonato JA, Mercurio F, Karin M. NF-kappaB and the link between inflammation and cancer. Immunol Rev. 2012;246:379-400.
    • (2012) Immunol Rev. , vol.246 , pp. 379-400
    • DiDonato, J.A.1    Mercurio, F.2    Karin, M.3
  • 67
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and i kappa B proteins: New discoveries and insights
    • Baldwin AS Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol. 1996;14:649-683.
    • (1996) Annu Rev Immunol. , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 68
    • 0028181648 scopus 로고
    • Enhanced i kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines
    • Miyamoto S, Chiao PJ, Verma IM. Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines. Mol Cell Biol. 1994;14:3276-3282.
    • (1994) Mol Cell Biol. , vol.14 , pp. 3276-3282
    • Miyamoto, S.1    Chiao, P.J.2    Verma, I.M.3
  • 69
    • 0033998441 scopus 로고    scopus 로고
    • Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear export
    • Tam WF, Lee LH, Davis L, et al. Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear export. Mol Cell Biol. 2000;20:2269-2284.
    • (2000) Mol Cell Biol. , vol.20 , pp. 2269-2284
    • Tam, W.F.1    Lee, L.H.2    Davis, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.