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Volumn 11, Issue 7, 2005, Pages 2518-2525

Nuclear factor-κB activation correlates with better prognosis and Akt activation in human gastric cancer

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KANGAI 1; LUCIFERASE; PROTEIN BCL 2; PROTEIN KINASE B; SMAD4 PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; AKT1 PROTEIN, HUMAN; ANDROSTANE DERIVATIVE; CHROMONE DERIVATIVE; HYBRID PROTEIN; MESSENGER RNA; MORPHOLINE DERIVATIVE; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; TRANSCRIPTION FACTOR RELA; WORTMANNIN;

EID: 17644400134     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-1282     Document Type: Article
Times cited : (82)

References (31)
  • 1
    • 0029882053 scopus 로고    scopus 로고
    • Bcl-2 expression and allelic loss of the p53 gene in gastric carcinomas
    • Saegusa M, Takano Y, Kamata Y, Okayasu J. Bcl-2 expression and allelic loss of the p53 gene in gastric carcinomas. J Cancer Res Clin Oncol 1996;122:427-32.
    • (1996) J Cancer Res Clin Oncol , vol.122 , pp. 427-432
    • Saegusa, M.1    Takano, Y.2    Kamata, Y.3    Okayasu, J.4
  • 2
    • 0031872529 scopus 로고    scopus 로고
    • Intramucosal carcinomas of the stomach: Phenotypic expression and loss of heterozygosity at microsatellites linked to the APC gene
    • Wu LB, Kushima R, Borchard F, Molsberger G, Hattori T. Intramucosal carcinomas of the stomach: phenotypic expression and loss of heterozygosity at microsatellites linked to the APC gene. Pathol Res Pract 1998;194:405-11.
    • (1998) Pathol Res Pract , vol.194 , pp. 405-411
    • Wu, L.B.1    Kushima, R.2    Borchard, F.3    Molsberger, G.4    Hattori, T.5
  • 3
    • 0033917229 scopus 로고    scopus 로고
    • Cellular phenotypes of differentiated-type adenocarcinomas and precancerous lesions of the stomach are dependent on the genetic pathway
    • Endoh Y, Sakata K, Tamura G, et al. Cellular phenotypes of differentiated-type adenocarcinomas and precancerous lesions of the stomach are dependent on the genetic pathway. J Pathol 2000;191:257-63.
    • (2000) J Pathol , vol.191 , pp. 257-263
    • Endoh, Y.1    Sakata, K.2    Tamura, G.3
  • 4
    • 0344406232 scopus 로고    scopus 로고
    • Increased nuclear factor-κB activation is related to the tumor development of renal cell carcinoma
    • Oya M, Takayanagi A, Horiguchi A, et al. Increased nuclear factor-κB activation is related to the tumor development of renal cell carcinoma. Carcinogenesis 2003;24:377-84.
    • (2003) Carcinogenesis , vol.24 , pp. 377-384
    • Oya, M.1    Takayanagi, A.2    Horiguchi, A.3
  • 5
    • 0037426670 scopus 로고    scopus 로고
    • NF-κB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix
    • Nair A, Venkatraman M, Maliekal TT, Nair B, Karunagaran D. NF-κB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix. Oncogene 2003;22:50-8.
    • (2003) Oncogene , vol.22 , pp. 50-58
    • Nair, A.1    Venkatraman, M.2    Maliekal, T.T.3    Nair, B.4    Karunagaran, D.5
  • 6
    • 1642334954 scopus 로고    scopus 로고
    • NF-κB activation in esophageal adenocarcinoma: Relationship to Barrett's metaplasia, survival, and response to neo-adjuvant chemoradiotherapy
    • Abdel-Latif MM, O'Riordan J, Windle HJ, et al. NF-κB activation in esophageal adenocarcinoma: relationship to Barrett's metaplasia, survival, and response to neo-adjuvant chemoradiotherapy. Ann Surg 2004;239:491-500.
    • (2004) Ann Surg , vol.239 , pp. 491-500
    • Abdel-Latif, M.M.1    O'Riordan, J.2    Windle, H.J.3
  • 7
    • 0033624673 scopus 로고    scopus 로고
    • Nuclear factor κB subunits induce epithelial cell growth arrest
    • Seitz CS, Deng H, Hinata K, Lin Q, Khavari PA. Nuclear factor κB subunits induce epithelial cell growth arrest. Cancer Res 2000;60:4085-92.
    • (2000) Cancer Res , vol.60 , pp. 4085-4092
    • Seitz, C.S.1    Deng, H.2    Hinata, K.3    Lin, Q.4    Khavari, P.A.5
  • 8
    • 0037242595 scopus 로고    scopus 로고
    • Function of nuclear factor κB in pancreatic cancer metastasis
    • Fujioka S, Sclabas GM, Schmidt C, et al. Function of nuclear factor κB in pancreatic cancer metastasis. Clin Cancer Res 2003;9:346-54.
    • (2003) Clin Cancer Res , vol.9 , pp. 346-354
    • Fujioka, S.1    Sclabas, G.M.2    Schmidt, C.3
  • 9
    • 1642380279 scopus 로고    scopus 로고
    • Helicobacter pylori induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-κB and RhoA: Implications for invasion and apoptosis
    • Varro A, Noble P-JM, Pritchard M, et al. Helicobacter pylori induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-κB and RhoA: implications for invasion and apoptosis. Cancer Res 2004;64:1695-702.
    • (2004) Cancer Res , vol.64 , pp. 1695-1702
    • Varro, A.1    Noble, P.-J.M.2    Pritchard, M.3
  • 10
    • 0035542950 scopus 로고    scopus 로고
    • Nuclear Factor-κB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue
    • Sasaki N, Morisaki T, Hashizume K, et al. Nuclear Factor-κB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue. Clin Cancer Res 2001;7:4136-42.
    • (2001) Clin Cancer Res , vol.7 , pp. 4136-4142
    • Sasaki, N.1    Morisaki, T.2    Hashizume, K.3
  • 11
    • 0037987700 scopus 로고    scopus 로고
    • Tumour suppressor gene expression correlates with gastric cancer prognosis
    • Lee HS, Lee HK, Kim HS, Yang HK, Kim WH. Tumour suppressor gene expression correlates with gastric cancer prognosis. J Pathol 2003;200:39-46.
    • (2003) J Pathol , vol.200 , pp. 39-46
    • Lee, H.S.1    Lee, H.K.2    Kim, H.S.3    Yang, H.K.4    Kim, W.H.5
  • 12
    • 0242526105 scopus 로고    scopus 로고
    • Expression of a splice variant of KAI1, a tumor metastasis suppressor gene, influences tumor invasion and progression
    • Lee JH, Seo YW, Park SR, Kim YJ, Kim KK. Expression of a splice variant of KAI1, a tumor metastasis suppressor gene, influences tumor invasion and progression. Cancer Res 2003;63:7247-55.
    • (2003) Cancer Res , vol.63 , pp. 7247-7255
    • Lee, J.H.1    Seo, Y.W.2    Park, S.R.3    Kim, Y.J.4    Kim, K.K.5
  • 13
    • 0035862151 scopus 로고    scopus 로고
    • Nuclear factor-κB-dependent expression of metastasis suppressor KAI1/CD82 gene in lung cancer cell lines expressing mutant p53
    • Shinohara T, Miki T, Nishimura N, et al. Nuclear factor-κB- dependent expression of metastasis suppressor KAI1/CD82 gene in lung cancer cell lines expressing mutant p53. Cancer Res 2001;61:673-8.
    • (2001) Cancer Res , vol.61 , pp. 673-678
    • Shinohara, T.1    Miki, T.2    Nishimura, N.3
  • 14
  • 16
    • 0035941298 scopus 로고    scopus 로고
    • Internalin B activates nuclear factor-κB via Ras, phosphoinositide 3-kinase, and Akt
    • Mansell A, Khelef N, Cossart P, O'Neill LAJ. Internalin B activates nuclear factor-κB via Ras, phosphoinositide 3-kinase, and Akt. J Biol Chem 2001;276:43597-603.
    • (2001) J Biol Chem , vol.276 , pp. 43597-43603
    • Mansell, A.1    Khelef, N.2    Cossart, P.3    O'Neill, L.A.J.4
  • 17
    • 0035957951 scopus 로고    scopus 로고
    • Interferon α/β promotes cell survival by activating nuclear factor κB through phosphatidylinositol 3-kinase and Akt
    • Yang CH, Murti A, Pfeffer SR, Kim JG, Donner DB, Pfeffer LM. Interferon α/β promotes cell survival by activating nuclear factor κB through phosphatidylinositol 3-kinase and Akt. J Biol Chem 2001;276:13756-61.
    • (2001) J Biol Chem , vol.276 , pp. 13756-13761
    • Yang, C.H.1    Murti, A.2    Pfeffer, S.R.3    Kim, J.G.4    Donner, D.B.5    Pfeffer, L.M.6
  • 18
    • 0742272099 scopus 로고    scopus 로고
    • Constitutive NF-κB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway
    • Birkenkamp KU, Geugien M, Schepers H, Westra J, Lemmink HH, Vellenga E. Constitutive NF-κB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway. Leukemia 2004;18:103-12.
    • (2004) Leukemia , vol.18 , pp. 103-112
    • Birkenkamp, K.U.1    Geugien, M.2    Schepers, H.3    Westra, J.4    Lemmink, H.H.5    Vellenga, E.6
  • 19
    • 0034720896 scopus 로고    scopus 로고
    • Kinase regulation in inflammatory response
    • Delhase M, Li N, Karin M. Kinase regulation in inflammatory response. Nature 2000;406:367-8.
    • (2000) Nature , vol.406 , pp. 367-368
    • Delhase, M.1    Li, N.2    Karin, M.3
  • 20
    • 0035887205 scopus 로고    scopus 로고
    • E1A inhibition of radiation-induced NF-κB activity through suppression of IKK activity and IκB degradation, independent of Akt activation
    • Shao R, Tsai EM, Wei K, et al. E1A inhibition of radiation-induced NF-κB activity through suppression of IKK activity and IκB degradation, independent of Akt activation. Cancer Res 2001;61:7413-6.
    • (2001) Cancer Res , vol.61 , pp. 7413-7416
    • Shao, R.1    Tsai, E.M.2    Wei, K.3
  • 21
    • 0035883673 scopus 로고    scopus 로고
    • MUC1, MUC2, MUC5AC, and MUC6 expressions in gastric carcinomas
    • Lee HS, Lee HK, Kim HS, Yang HK, Kim YI, Kim WH. MUC1, MUC2, MUC5AC, and MUC6 expressions in gastric carcinomas. Cancer 2001;92:1427-34.
    • (2001) Cancer , vol.92 , pp. 1427-1434
    • Lee, H.S.1    Lee, H.K.2    Kim, H.S.3    Yang, H.K.4    Kim, Y.I.5    Kim, W.H.6
  • 22
    • 0038360113 scopus 로고    scopus 로고
    • Philadelphia: Lippincott-Raven
    • American Joint Committee on Cancer. AJCC cancer staging manual. 5th ed. Philadelphia: Lippincott-Raven; 1997.
    • (1997) AJCC Cancer Staging Manual. 5th Ed.
  • 23
    • 0346494938 scopus 로고    scopus 로고
    • Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis
    • Nam SY, Lee HS, Jung G-A, et al. Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis. APMIS 2003;111: 1105-13.
    • (2003) APMIS , vol.111 , pp. 1105-1113
    • Nam, S.Y.1    Lee, H.S.2    Jung, G.-A.3
  • 24
    • 0035972152 scopus 로고    scopus 로고
    • Generation of fusion genes carrying drug resistance, green fluorescent protein, and herpes simplex virus thymidine kinase genes in a single cistron
    • Oh SC, Nam SY, Kwon HC, et al. Generation of fusion genes carrying drug resistance, green fluorescent protein, and herpes simplex virus thymidine kinase genes in a single cistron. Mol Cells 2001;11:192-7.
    • (2001) Mol Cells , vol.11 , pp. 192-197
    • Oh, S.C.1    Nam, S.Y.2    Kwon, H.C.3
  • 25
    • 0346399569 scopus 로고    scopus 로고
    • S by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers
    • S by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers. Cancer Sci 2003;94:1066-73.
    • (2003) Cancer Sci , vol.94 , pp. 1066-1073
    • Nam, S.Y.1    Jung, G.-A.2    Hur, G.-C.3
  • 26
    • 0033045597 scopus 로고    scopus 로고
    • Prognostic impact of stromal cell-derived urokinase-type plasminogen activator in gastric carcinoma
    • Okusa Y, Ichikura T, Mochizuki H. Prognostic impact of stromal cell-derived urokinase-type plasminogen activator in gastric carcinoma. Cancer 1999;85: 1033-8.
    • (1999) Cancer , vol.85 , pp. 1033-1038
    • Okusa, Y.1    Ichikura, T.2    Mochizuki, H.3
  • 27
    • 17644415076 scopus 로고    scopus 로고
    • Molecular markers in gastric cancer: Can they predict prognosis?
    • Kim SJ, Kim YH. Molecular markers in gastric cancer: can they predict prognosis? Cancer Res Treat 2003;35:1-2.
    • (2003) Cancer Res Treat , vol.35 , pp. 1-2
    • Kim, S.J.1    Kim, Y.H.2
  • 28
    • 18244391514 scopus 로고    scopus 로고
    • Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients
    • Perez-Tenorio G, Stal O. Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients. Br J Cancer 2002;86:540-5.
    • (2002) Br J Cancer , vol.86 , pp. 540-545
    • Perez-Tenorio, G.1    Stal, O.2
  • 29
    • 0348049845 scopus 로고    scopus 로고
    • Incidence, mechanism and prognostic value of activated AKT in pancreas cancer
    • Schlieman MG, Fahy BN, Ramsamooj R, Beckett L, Bold RJ. Incidence, mechanism and prognostic value of activated AKT in pancreas cancer. Br J Cancer 2003;89:2110-5.
    • (2003) Br J Cancer , vol.89 , pp. 2110-2115
    • Schlieman, M.G.1    Fahy, B.N.2    Ramsamooj, R.3    Beckett, L.4    Bold, R.J.5
  • 30
    • 4544223402 scopus 로고    scopus 로고
    • The role of PTEN and its signaling pathways, including AKT, in breast cancer: An assessment of relationships with other prognostic factors and with outcome
    • Panigrahi AR, Pinder SE, Chan SY, Paish EC, Pobertson JFR, Ellis IO. The role of PTEN and its signaling pathways, including AKT, in breast cancer: an assessment of relationships with other prognostic factors and with outcome. J Pathol 2004;204:93-100.
    • (2004) J Pathol , vol.204 , pp. 93-100
    • Panigrahi, A.R.1    Pinder, S.E.2    Chan, S.Y.3    Paish, E.C.4    Pobertson, J.F.R.5    Ellis, I.O.6
  • 31
    • 8444240824 scopus 로고    scopus 로고
    • Early involvement of the phophatidylinositol 3-kinase/Akt pathway in lung cancer progression
    • Massion PP, Taflan PM, Shyr Y, et al. Early involvement of the phophatidylinositol 3-kinase/Akt pathway in lung cancer progression. Am J Respir Crit Care Med 2004;170:1088-94.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 1088-1094
    • Massion, P.P.1    Taflan, P.M.2    Shyr, Y.3


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