Effects of Muscone on the Expression of P-gp, MMP-9 on Blood–Brain Barrier Model In Vitro

Cellular and Molecular Neurobiology

Volumn 35, Issue 8, 2015, Pages 1105-1115

  Wang, Guang Yun ^a,b   Wang, Ning ^a,b   Liao, Hua Ning ^a,b  

^a ANHUI UNIVERSITY OF CHINESE MEDICINE   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Blood brain barrier (BBB); Matrix metalloproteinase 9 (MMP 9); Muscone; P glycoprotein (P gp); Tight junction

Indexed keywords

ALKALINE PHOSPHATASE; GAMMA GLUTAMYLTRANSFERASE; GELATINASE B; GLUCOSE; MULTIDRUG RESISTANCE PROTEIN; MUSCONE; OXYGEN; CYCLOALKANE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; BASEMENT MEMBRANE; BLOOD BRAIN BARRIER; CELL VIABILITY; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; COCULTURE; CONTROLLED STUDY; DRUG PENETRATION; DRUG TRANSPORT; ENZYME ACTIVITY; ENZYME INHIBITION; GAS CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIMULATION; TIGHT JUNCTION; TRANSENDOTHELIAL ELECTRICAL RESISTANCE; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DOSE RESPONSE; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; MALE; METABOLISM; NEWBORN; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BLOOD-BRAIN BARRIER; COCULTURE TECHNIQUES; CYCLOPARAFFINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MATRIX METALLOPROTEINASE 9; P-GLYCOPROTEIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84943816685     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-015-0204-8     Document Type: Article

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