Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes

Epigenetics

Volumn 10, Issue 6, 2015, Pages 484-495

  Dozmorov, Mikhail G ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Aging; ENCODE; Epigenetics; Epigenomics; GenomeRunner; Methylation; Polycomb; PRC2

Indexed keywords

HISTONE TRIMETHYLATED LYSINE 27 OF HISTONE H3; HISTONE TRIMETHYLATED LYSINE 36 OF HISTONE H3; HISTONE TRIMETHYLATED LYSINE 4 OF HISTONE H3; HISTONE TRIMETHYLATED LYSINE 79 OF HISTONE H3; NUCLEAR PROTEIN; POLYCOMB PROTEIN SUZ12; POLYCOMB REPRESSIVE COMPLEX 2; RNA POLYMERASE II; SOLUTE CARRIER FAMILY 10, MEMBER 4 PROTEIN; TRANSCRIPTION FACTOR CTCF; TRANSCRIPTION FACTOR EZH2; TRANSMEMBRANE PROTEIN 61; UNCLASSIFIED DRUG; CCCTC-BINDING FACTOR; CHROMATIN; EZH2 PROTEIN, HUMAN; HISTONE; PROTEIN BINDING; REPRESSOR PROTEIN; SUZ12 PROTEIN, HUMAN;

AGING; ARTICLE; BINDING SITE; CELL LINE; DNA METHYLATION; DNA STRUCTURE; DNA TRANSCRIPTION; EMBRYO CELL; EPIGENETICS; EXTRACELLULAR MATRIX; GENE; GENE EXPRESSION; GENE FUNCTION; HUMAN; INTRACELLULAR SIGNALING; MORPHOGENESIS; POLYCOMB REPRESSIVE COMPLEX 2 GENE; PROTEIN BINDING; SEQUENCE HOMOLOGY; SYNAPTIC TRANSMISSION; CHROMATIN; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PROMOTER REGION; PROTEIN TERTIARY STRUCTURE;

AGING; BINDING SITES; CELL LINE; CHROMATIN; DNA METHYLATION; ENHANCER OF ZESTE HOMOLOG 2 PROTEIN; EPIGENOMICS; GENE EXPRESSION REGULATION; HISTONES; HUMANS; POLYCOMB REPRESSIVE COMPLEX 2; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS;

EID: 84943812884     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2015.1040619     Document Type: Article

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