Tomoregulin (TMEFF2) Binds Alzheimer's Disease Amyloid-β (Aβ) Oligomer and AβPP and Protects Neurons from Aβ-Induced Toxicity

Journal of Alzheimer's Disease

Volumn 48, Issue 3, 2015, Pages 731-743

  Hong, Hyun Seok ^a,e   Maezawa, Izumi ^a,b   Petrlova, Jitka ^c,f   Zhao, Xiao Yan ^d   C Voss, John ^c   Jin, Lee Way ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Global Biologics Research   (United States)

^e Medifron DBT   (South Korea)

^f LUND UNIVERSITY   (Sweden)

Author keywords

Alzheimer's disease; amyloid; binding; neuroprotection; neurotoxicity; tomoregulin

Indexed keywords

3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 2 HYDROXY 1 PROPANESULFONIC ACID; ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; MEMBRANE PROTEIN; TOMOREGULIN; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN; SECRETASE; TMEFF2 PROTEIN, HUMAN; TMEFF2 PROTEIN, MOUSE; TUMOR PROTEIN;

ADULT; ALZHEIMER DISEASE; AMYLOID BETA INDUCED TOXICITY; AMYLOID PLAQUE; ANIMAL CELL; ARTICLE; ASTROCYTE; ATOMIC FORCE MICROSCOPY; BINDING ASSAY; CELL CULTURE; CELL LYSATE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; INTERNALIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NERVE CELL; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SURFACE PLASMON RESONANCE; SURFACE PLASMON RESONANCE SPECTROSCOPY; TANDEM MASS SPECTROMETRY; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL SURVIVAL; CONFOCAL MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RNA INTERFERENCE; TRANSGENIC MOUSE; TUMOR CELL LINE;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASTROCYTES; CELL LINE, TUMOR; CELL SURVIVAL; ELECTRON SPIN RESONANCE SPECTROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; HUMANS; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; NEOPLASM PROTEINS; NEURONS; PLAQUE, AMYLOID; RECOMBINANT PROTEINS; RNA INTERFERENCE; SURFACE PLASMON RESONANCE;

EID: 84943752604     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150318     Document Type: Article

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