메뉴 건너뛰기




Volumn 54, Issue 6, 2015, Pages 1001-1012

1,25-Dihydroxyvitamin D3/vitamin D receptor suppresses brown adipocyte differentiation and mitochondrial respiration

Author keywords

Brown adipocyte; Mitochondrial respiration; UCP1; Vitamin D receptor

Indexed keywords

CALCITRIOL; COLECALCIFEROL 24 HYDROXYLASE; MESSENGER RNA; UNCOUPLING PROTEIN 1; VITAMIN D RECEPTOR; CALCIDIOL 1 MONOOXYGENASE; CALCITRIOL RECEPTOR; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 84943699081     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-014-0778-9     Document Type: Article
Times cited : (66)

References (36)
  • 1
    • 0347989317 scopus 로고    scopus 로고
    • Brown adipose tissue: function and physiological significance
    • COI: 1:CAS:528:DC%2BD2cXotl2qsQ%3D%3D
    • Cannon B, Nedergaard J (2004) Brown adipose tissue: function and physiological significance. Physiol Rev 84(1):277–359. doi:10.1152/physrev.00015.2003
    • (2004) Physiol Rev , vol.84 , Issue.1 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 2
    • 18844458927 scopus 로고    scopus 로고
    • Respiration uncoupling and metabolism in the control of energy expenditure
    • COI: 1:CAS:528:DC%2BD2MXls1aqtrs%3D
    • Ricquier D (2005) Respiration uncoupling and metabolism in the control of energy expenditure. Proc Nutr Soc 64(1):47–52
    • (2005) Proc Nutr Soc , vol.64 , Issue.1 , pp. 47-52
    • Ricquier, D.1
  • 3
    • 0021322138 scopus 로고
    • Thermogenic mechanisms in brown fat
    • COI: 1:CAS:528:DyaL2cXhslWqtb8%3D
    • Nicholls DG, Locke RM (1984) Thermogenic mechanisms in brown fat. Physiol Rev 64(1):1–64
    • (1984) Physiol Rev , vol.64 , Issue.1 , pp. 1-64
    • Nicholls, D.G.1    Locke, R.M.2
  • 4
    • 70349334680 scopus 로고    scopus 로고
    • The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue
    • COI: 1:CAS:528:DC%2BD1MXhtFagsrnJ
    • Zingaretti MC, Crosta F, Vitali A, Guerrieri M, Frontini A, Cannon B, Nedergaard J, Cinti S (2009) The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue. Faseb J 23(9):3113–3120. doi:10.1096/fj.09-133546
    • (2009) Faseb J , vol.23 , Issue.9 , pp. 3113-3120
    • Zingaretti, M.C.1    Crosta, F.2    Vitali, A.3    Guerrieri, M.4    Frontini, A.5    Cannon, B.6    Nedergaard, J.7    Cinti, S.8
  • 10
    • 84884295368 scopus 로고    scopus 로고
    • Brown adipose tissue: clinical impact of a re-discovered thermogenic organ
    • COI: 1:CAS:528:DC%2BC3sXhtFWqtr%2FP
    • Vijgen GH, van Marken Lichtenbelt WD (2013) Brown adipose tissue: clinical impact of a re-discovered thermogenic organ. Front Biosci (Elite Ed) E5:823–833
    • (2013) Front Biosci (Elite Ed) , vol.E5 , pp. 823-833
    • Vijgen, G.H.1    van Marken Lichtenbelt, W.D.2
  • 12
    • 84871299721 scopus 로고    scopus 로고
    • Vitamin D signalling in adipose tissue
    • COI: 1:CAS:528:DC%2BC38XhvVCisLvL
    • Ding C, Gao D, Wilding J, Trayhurn P, Bing C (2012) Vitamin D signalling in adipose tissue. Br J Nutr 108(11):1915–1923. doi:10.1017/S0007114512003285
    • (2012) Br J Nutr , vol.108 , Issue.11 , pp. 1915-1923
    • Ding, C.1    Gao, D.2    Wilding, J.3    Trayhurn, P.4    Bing, C.5
  • 13
    • 33744965569 scopus 로고    scopus 로고
    • Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells
    • COI: 1:CAS:528:DC%2BD28XjsFWjsb8%3D
    • Blumberg JM, Tzameli I, Astapova I, Lam FS, Flier JS, Hollenberg AN (2006) Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells. J Biol Chem 281(16):11205–11213. doi:10.1074/jbc.M510343200
    • (2006) J Biol Chem , vol.281 , Issue.16 , pp. 11205-11213
    • Blumberg, J.M.1    Tzameli, I.2    Astapova, I.3    Lam, F.S.4    Flier, J.S.5    Hollenberg, A.N.6
  • 14
    • 33646385595 scopus 로고    scopus 로고
    • Molecular mechanism of 1,25-dihydroxyvitamin D3 inhibition of adipogenesis in 3T3-L1 cells
    • COI: 1:CAS:528:DC%2BD28XkvFKmu7c%3D
    • Kong J, Li YC (2006) Molecular mechanism of 1,25-dihydroxyvitamin D3 inhibition of adipogenesis in 3T3-L1 cells. Am J Physiol Endocrinol Metab 290(5):E916–E924. doi:10.1152/ajpendo.00410.2005
    • (2006) Am J Physiol Endocrinol Metab , vol.290 , Issue.5 , pp. 916-924
    • Kong, J.1    Li, Y.C.2
  • 15
    • 84871272732 scopus 로고    scopus 로고
    • 25-hydroxyvitamin D(3) and 1,25-dihydroxyvitamin D(3) promote the differentiation of human subcutaneous preadipocytes
    • COI: 1:CAS:528:DC%2BC3sXktVSnsg%3D%3D
    • Nimitphong H, Holick MF, Fried SK, Lee MJ (2012) 25-hydroxyvitamin D(3) and 1,25-dihydroxyvitamin D(3) promote the differentiation of human subcutaneous preadipocytes. PLoS ONE 7(12):e52171. doi:10.1371/journal.pone.0052171
    • (2012) PLoS ONE , vol.7 , Issue.12 , pp. 52171
    • Nimitphong, H.1    Holick, M.F.2    Fried, S.K.3    Lee, M.J.4
  • 16
    • 65649133127 scopus 로고    scopus 로고
    • Involvement of the vitamin D receptor in energy metabolism: regulation of uncoupling proteins
    • COI: 1:CAS:528:DC%2BD1MXkvVyhtLs%3D
    • Wong KE, Szeto FL, Zhang W, Ye H, Kong J, Zhang Z, Sun XJ, Li YC (2009) Involvement of the vitamin D receptor in energy metabolism: regulation of uncoupling proteins. Am J Physiol Endocrinol Metab 296(4):E820–E828. doi:10.1152/ajpendo.90763.2008
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , Issue.4 , pp. 820-828
    • Wong, K.E.1    Szeto, F.L.2    Zhang, W.3    Ye, H.4    Kong, J.5    Zhang, Z.6    Sun, X.J.7    Li, Y.C.8
  • 17
    • 80053202578 scopus 로고    scopus 로고
    • Targeted expression of human vitamin D receptor in adipocytes decreases energy expenditure and induces obesity in mice
    • COI: 1:CAS:528:DC%2BC3MXht1ajtLbP
    • Wong KE, Kong J, Zhang W, Szeto FL, Ye H, Deb DK, Brady MJ, Li YC (2011) Targeted expression of human vitamin D receptor in adipocytes decreases energy expenditure and induces obesity in mice. J Biol Chem 286(39):33804–33810. doi:10.1074/jbc.M111.257568
    • (2011) J Biol Chem , vol.286 , Issue.39 , pp. 33804-33810
    • Wong, K.E.1    Kong, J.2    Zhang, W.3    Szeto, F.L.4    Ye, H.5    Deb, D.K.6    Brady, M.J.7    Li, Y.C.8
  • 18
    • 80053259945 scopus 로고    scopus 로고
    • NOD1 activation induces proinflammatory gene expression and insulin resistance in 3T3-L1 adipocytes
    • COI: 1:CAS:528:DC%2BC3MXhtlersb3M
    • Zhao L, Hu P, Zhou Y, Purohit J, Hwang D (2011) NOD1 activation induces proinflammatory gene expression and insulin resistance in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metabol 301(4):E587–E598. doi:10.1152/ajpendo.00709.2010
    • (2011) Am J Physiol Endocrinol Metabol , vol.301 , Issue.4 , pp. 587-598
    • Zhao, L.1    Hu, P.2    Zhou, Y.3    Purohit, J.4    Hwang, D.5
  • 19
    • 0036010603 scopus 로고    scopus 로고
    • Novel adipocyte lines from brown fat: a model system for the study of differentiation, energy metabolism, and insulin action
    • COI: 1:CAS:528:DC%2BD38XjsFWjt7s%3D
    • Klein J, Fasshauer M, Klein HH, Benito M, Kahn CR (2002) Novel adipocyte lines from brown fat: a model system for the study of differentiation, energy metabolism, and insulin action. BioEssays 24(4):382–388. doi:10.1002/bies.10058
    • (2002) BioEssays , vol.24 , Issue.4 , pp. 382-388
    • Klein, J.1    Fasshauer, M.2    Klein, H.H.3    Benito, M.4    Kahn, C.R.5
  • 20
    • 84864327615 scopus 로고    scopus 로고
    • Differential effects of environmental chemicals and food contaminants on adipogenesis, biomarker release and PPARgamma activation
    • COI: 1:CAS:528:DC%2BC38Xms1Wqs70%3D
    • Taxvig C, Dreisig K, Boberg J, Nellemann C, Schelde AB, Pedersen D, Boergesen M, Mandrup S, Vinggaard AM (2012) Differential effects of environmental chemicals and food contaminants on adipogenesis, biomarker release and PPARgamma activation. Mol Cell Endocrinol 361(1–2):106–115. doi:10.1016/j.mce.2012.03.021
    • (2012) Mol Cell Endocrinol , vol.361 , Issue.1-2 , pp. 106-115
    • Taxvig, C.1    Dreisig, K.2    Boberg, J.3    Nellemann, C.4    Schelde, A.B.5    Pedersen, D.6    Boergesen, M.7    Mandrup, S.8    Vinggaard, A.M.9
  • 24
    • 84899461858 scopus 로고    scopus 로고
    • BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells
    • COI: 1:CAS:528:DC%2BC2cXlvVCht7Y%3D
    • Elsen M, Raschke S, Tennagels N, Schwahn U, Jelenik T, Roden M, Romacho T, Eckel J (2014) BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells. Am J Physiol Cell Physiol 306(5):C431–C440. doi:10.1152/ajpcell.00290.2013
    • (2014) Am J Physiol Cell Physiol , vol.306 , Issue.5 , pp. 431-440
    • Elsen, M.1    Raschke, S.2    Tennagels, N.3    Schwahn, U.4    Jelenik, T.5    Roden, M.6    Romacho, T.7    Eckel, J.8
  • 25
    • 84894030350 scopus 로고    scopus 로고
    • Role of bone morphogenetic protein 4 in the differentiation of brown fat-like adipocytes
    • COI: 1:CAS:528:DC%2BC2cXjs1yntLk%3D
    • Xue R, Wan Y, Zhang S, Zhang Q, Ye H, Li Y (2014) Role of bone morphogenetic protein 4 in the differentiation of brown fat-like adipocytes. Am J Physiol Endocrinol Metabol 306(4):E363–E372. doi:10.1152/ajpendo.00119.2013
    • (2014) Am J Physiol Endocrinol Metabol , vol.306 , Issue.4 , pp. 363-372
    • Xue, R.1    Wan, Y.2    Zhang, S.3    Zhang, Q.4    Ye, H.5    Li, Y.6
  • 26
    • 33751507112 scopus 로고    scopus 로고
    • Decreased brown adipocyte recruitment and thermogenic capacity in mice with impaired peroxisome proliferator-activated receptor (P465L PPARgamma) function
    • COI: 1:CAS:528:DC%2BD28Xht1yqtr%2FI
    • Gray SL, Dalla Nora E, Backlund EC, Manieri M, Virtue S, Noland RC, O’Rahilly S, Cortright RN, Cinti S, Cannon B, Vidal-Puig A (2006) Decreased brown adipocyte recruitment and thermogenic capacity in mice with impaired peroxisome proliferator-activated receptor (P465L PPARgamma) function. Endocrinology 147(12):5708–5714. doi:10.1210/en.2006-0684
    • (2006) Endocrinology , vol.147 , Issue.12 , pp. 5708-5714
    • Gray, S.L.1    Dalla Nora, E.2    Backlund, E.C.3    Manieri, M.4    Virtue, S.5    Noland, R.C.6    O’Rahilly, S.7    Cortright, R.N.8    Cinti, S.9    Cannon, B.10    Vidal-Puig, A.11
  • 27
    • 52649150323 scopus 로고    scopus 로고
    • Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist
    • COI: 1:CAS:528:DC%2BD1cXhtVaktr3L
    • Petrovic N, Shabalina IG, Timmons JA, Cannon B, Nedergaard J (2008) Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist. Am J Physiol Endocrinol Metab 295(2):E287–E296. doi:10.1152/ajpendo.00035.2008
    • (2008) Am J Physiol Endocrinol Metab , vol.295 , Issue.2 , pp. 287-296
    • Petrovic, N.1    Shabalina, I.G.2    Timmons, J.A.3    Cannon, B.4    Nedergaard, J.5
  • 28
    • 3843083938 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice
    • COI: 1:CAS:528:DC%2BD2cXmtlCqsbk%3D
    • Sell H, Berger JP, Samson P, Castriota G, Lalonde J, Deshaies Y, Richard D (2004) Peroxisome proliferator-activated receptor gamma agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice. Endocrinology 145(8):3925–3934. doi:10.1210/en.2004-0321
    • (2004) Endocrinology , vol.145 , Issue.8 , pp. 3925-3934
    • Sell, H.1    Berger, J.P.2    Samson, P.3    Castriota, G.4    Lalonde, J.5    Deshaies, Y.6    Richard, D.7
  • 29
    • 78650633662 scopus 로고    scopus 로고
    • Uncoupling protein 1 expression and high-fat diets
    • COI: 1:CAS:528:DC%2BC3MXhslWns7g%3D
    • Fromme T, Klingenspor M (2011) Uncoupling protein 1 expression and high-fat diets. Am J Physiol Regul Integr Comp Physiol 300(1):R1–R8. doi:10.1152/ajpregu.00411.2010
    • (2011) Am J Physiol Regul Integr Comp Physiol , vol.300 , Issue.1 , pp. 1-8
    • Fromme, T.1    Klingenspor, M.2
  • 30
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • COI: 1:CAS:528:DyaK1cXit1Klsb8%3D
    • Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92(6):829–839
    • (1998) Cell , vol.92 , Issue.6 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 32
    • 84873518501 scopus 로고    scopus 로고
    • Adaptive thermogenesis in adipocytes: is beige the new brown?
    • COI: 1:CAS:528:DC%2BC3sXjt1Cgtr0%3D
    • Wu J, Cohen P, Spiegelman BM (2013) Adaptive thermogenesis in adipocytes: is beige the new brown? Genes Dev 27(3):234–250. doi:10.1101/gad.211649.112
    • (2013) Genes Dev , vol.27 , Issue.3 , pp. 234-250
    • Wu, J.1    Cohen, P.2    Spiegelman, B.M.3
  • 33
    • 84875835392 scopus 로고
    • Palou A (2013) Pharmacological and nutritional agents promoting browning of white adipose tissue
    • Bonet ML, Oliver P (1831) Palou A (2013) Pharmacological and nutritional agents promoting browning of white adipose tissue. Biochim Biophys Acta 5:969–985. doi:10.1016/j.bbalip.2012.12.002
    • (1831) Biochim Biophys Acta , vol.5 , pp. 969-985
    • Bonet, M.L.1    Oliver, P.2
  • 34
    • 59649099370 scopus 로고    scopus 로고
    • Lean phenotype and resistance to diet-induced obesity in vitamin D receptor knockout mice correlates with induction of uncoupling protein-1 in white adipose tissue
    • COI: 1:CAS:528:DC%2BD1MXhs1Sgs70%3D
    • Narvaez CJ, Matthews D, Broun E, Chan M, Welsh J (2009) Lean phenotype and resistance to diet-induced obesity in vitamin D receptor knockout mice correlates with induction of uncoupling protein-1 in white adipose tissue. Endocrinology 150(2):651–661. doi:10.1210/en.2008-1118
    • (2009) Endocrinology , vol.150 , Issue.2 , pp. 651-661
    • Narvaez, C.J.1    Matthews, D.2    Broun, E.3    Chan, M.4    Welsh, J.5
  • 35
    • 84884798995 scopus 로고    scopus 로고
    • Cell-autonomous regulation of brown fat identity gene UCP1 by unliganded vitamin D receptor
    • COI: 1:CAS:528:DC%2BC3sXhs1Wltb7N
    • Malloy PJ, Feldman BJ (2013) Cell-autonomous regulation of brown fat identity gene UCP1 by unliganded vitamin D receptor. Mol Endocrinol 27(10):1632–1642. doi:10.1210/me.2013-1037
    • (2013) Mol Endocrinol , vol.27 , Issue.10 , pp. 1632-1642
    • Malloy, P.J.1    Feldman, B.J.2
  • 36


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.