1α,25-dihydroxyvitamin D3 acts via transforming growth factor-β to up-regulate expression of immunosuppressive CD73 on human CD4+ Foxp3- T cells

Immunology

Volumn 146, Issue 3, 2015, Pages 423-431

  Mann, Elizabeth H ^a   Chambers, Emma S ^a   Chen, Yin Huai ^a   Richards, David F ^a   Hawrylowicz, Catherine M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

1 ,25 dihydroxyvitamin D3; CD73; Foxp3; Transforming growth factor

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE TRIPHOSPHATE; ALPHA5 INTEGRIN; CALCITRIOL; CD39 ANTIGEN; CD4 ANTIGEN; CD51 ANTIGEN; GLYCOPHORIN A REPETITION PREDOMINANT PROTEIN; GLYCOPHORIN A REPETITIONS PREDOMINANT; GLYCOPROTEIN GP 96; LATENCY ASSOCIATED PEPTIDE; MESSENGER RNA; NEUROPILIN 1; THROMBOSPONDIN 1; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; LRRC32 PROTEIN, HUMAN; MEMBRANE PROTEIN; NT5E PROTEIN, HUMAN;

ARTICLE; CD4+ T LYMPHOCYTE; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOPATHOLOGY; INVESTIGATIVE PROCEDURES; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SUPPRESSOR CELL; UPREGULATION; DRUG EFFECTS; GENETICS; IMMUNOLOGY; IN VITRO STUDY; METABOLISM;

5'-NUCLEOTIDASE; CALCITRIOL; CD4-POSITIVE T-LYMPHOCYTES; FORKHEAD TRANSCRIPTION FACTORS; GPI-LINKED PROTEINS; HUMANS; IN VITRO TECHNIQUES; MEMBRANE PROTEINS; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84943658456     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12519     Document Type: Article

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