Mechanical stretch inhibits mesenchymal stem cell adipogenic differentiation through TGFβ1/Smad2 signaling

Journal of Biomechanics

Volumn 48, Issue 13, 2015, Pages 3656-3662

  Li, Runguang ^a   Liang, Liang ^a   Dou, Yonggang ^a   Huang, Zeping ^a   Mo, Huiting ^a   Wang, Yaning ^a   Yu, Bin ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Adipogenic differentiation; Mesenchymal stem cell; Smad2; Stretch; TGF 1

Indexed keywords

CELL CULTURE; FLOWCHARTING; PHOSPHORYLATION; PIGMENTS; SIGNALING; STEM CELLS; STRETCHING;

ADIPOGENIC DIFFERENTIATIONS; EXPERIMENTAL GROUPS; INTRACELLULAR SIGNALING PATHWAYS; MECHANICAL STRETCH; MESENCHYMAL STEM CELL; PHYSICAL MOVEMENTS; SIGNALING PATHWAYS; SMAD2;

CELL SIGNALING;

ADIPONECTIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; MADH2 PROTEIN, RAT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TGFB1 PROTEIN, RAT;

ADIPOCYTE; ADIPOGENESIS; ADIPONECTIN GENE; ANIMAL CELL; ARTICLE; CCAAT ENHANCER BINDING PROTEIN ALPHA GENE; CELL DIFFERENTIATION; CELL STIMULATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; INTRACELLULAR SIGNALING; MALE; MECHANICAL STRETCH; MESENCHYMAL STEM CELL; NONHUMAN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2 GENE; PRIORITY JOURNAL; PROCEDURES CONCERNING CELLS; PROTEIN EXPRESSION; RAT; STEM CELL CULTURE; ANIMAL; CELL CULTURE; CYTOLOGY; DOWN REGULATION; MECHANICAL STRESS; MESENCHYMAL STROMA CELL; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ADIPOCYTES; ADIPOGENESIS; ADIPONECTIN; ANIMALS; BENZAMIDES; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; CELLS, CULTURED; DIOXOLES; DOWN-REGULATION; MESENCHYMAL STROMAL CELLS; PHOSPHORYLATION; PPAR GAMMA; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; STRESS, MECHANICAL; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84943585321     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2015.08.013     Document Type: Article

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