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Volumn 52, Issue 1, 2013, Pages 454-464

Mechanical input restrains PPARγ2 expression and action to preserve mesenchymal stem cell multipotentiality

Author keywords

catenin; Adipogenesis; AP2; Bone marrow; Rosiglitazone

Indexed keywords

BETA CATENIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; ROSIGLITAZONE;

EID: 84870394058     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2012.08.122     Document Type: Article
Times cited : (38)

References (38)
  • 1
    • 84865001029 scopus 로고    scopus 로고
    • Donor age and long-term culture affect differentiation and proliferation of human bone marrow mesenchymal stem cells
    • Zaim M., Karaman S., Cetin G., Isik S. Donor age and long-term culture affect differentiation and proliferation of human bone marrow mesenchymal stem cells. Ann Hematol 2012, 91:1175-1186.
    • (2012) Ann Hematol , vol.91 , pp. 1175-1186
    • Zaim, M.1    Karaman, S.2    Cetin, G.3    Isik, S.4
  • 4
    • 0019726747 scopus 로고
    • Skeletal alterations in rats during space flight
    • Wronski T.J., Morey-Holton E., Jee W.S. Skeletal alterations in rats during space flight. Adv Space Res 1981, 1:135-140.
    • (1981) Adv Space Res , vol.1 , pp. 135-140
    • Wronski, T.J.1    Morey-Holton, E.2    Jee, W.S.3
  • 5
    • 2042548006 scopus 로고    scopus 로고
    • Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis
    • Zayzafoon M., Gathings W.E., McDonald J.M. Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis. Endocrinology 2004, 145:2421-2432.
    • (2004) Endocrinology , vol.145 , pp. 2421-2432
    • Zayzafoon, M.1    Gathings, W.E.2    McDonald, J.M.3
  • 7
    • 22944489618 scopus 로고    scopus 로고
    • Osteoporosis is associated with increased marrow fat content and decreased marrow fat unsaturation: a proton MR spectroscopy study
    • Yeung D.K., Griffith J.F., Antonio G.E., Lee F.K., Woo J., Leung P.C. Osteoporosis is associated with increased marrow fat content and decreased marrow fat unsaturation: a proton MR spectroscopy study. J Magn Reson Imaging 2005, 22:279-285.
    • (2005) J Magn Reson Imaging , vol.22 , pp. 279-285
    • Yeung, D.K.1    Griffith, J.F.2    Antonio, G.E.3    Lee, F.K.4    Woo, J.5    Leung, P.C.6
  • 9
    • 34249776946 scopus 로고    scopus 로고
    • Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis
    • David V., Martin A., Lafage-Proust M.H., Malaval L., Peyroche S., Jones D.B., et al. Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis. Endocrinology 2007, 148:2553-2562.
    • (2007) Endocrinology , vol.148 , pp. 2553-2562
    • David, V.1    Martin, A.2    Lafage-Proust, M.H.3    Malaval, L.4    Peyroche, S.5    Jones, D.B.6
  • 10
    • 49149084192 scopus 로고    scopus 로고
    • Climbing exercise enhances osteoblast differentiation and inhibits adipogenic differentiation with high expression of PTH/PTHrP receptor in bone marrow cells
    • Menuki K., Mori T., Sakai A., Sakuma M., Okimoto N., Shimizu Y., et al. Climbing exercise enhances osteoblast differentiation and inhibits adipogenic differentiation with high expression of PTH/PTHrP receptor in bone marrow cells. Bone 2008, 43:613-620.
    • (2008) Bone , vol.43 , pp. 613-620
    • Menuki, K.1    Mori, T.2    Sakai, A.3    Sakuma, M.4    Okimoto, N.5    Shimizu, Y.6
  • 11
    • 51849167786 scopus 로고    scopus 로고
    • Effects of hindlimb unloading on ex vivo growth and osteogenic/adipogenic potentials of bone marrow-derived mesenchymal stem cells in rats
    • Pan Z., Yang J., Guo C., Shi D., Shen D., Zheng Q., et al. Effects of hindlimb unloading on ex vivo growth and osteogenic/adipogenic potentials of bone marrow-derived mesenchymal stem cells in rats. Stem Cells Dev 2008, 17:795-804.
    • (2008) Stem Cells Dev , vol.17 , pp. 795-804
    • Pan, Z.1    Yang, J.2    Guo, C.3    Shi, D.4    Shen, D.5    Zheng, Q.6
  • 12
    • 71749108831 scopus 로고    scopus 로고
    • Mechanical loading regulates NFATC1 and {beta}-catenin signaling through a GSK3{beta} control node
    • Sen B., Styner M., Xie Z., Case N., Rubin C.T., Rubin J. Mechanical loading regulates NFATC1 and {beta}-catenin signaling through a GSK3{beta} control node. J Biol Chem 2009, 284:34607-34617.
    • (2009) J Biol Chem , vol.284 , pp. 34607-34617
    • Sen, B.1    Styner, M.2    Xie, Z.3    Case, N.4    Rubin, C.T.5    Rubin, J.6
  • 13
    • 79951721438 scopus 로고    scopus 로고
    • Mechanical signal influence on mesenchymal stem cell fate is enhanced by incorporation of refractory periods into the loading regimen
    • Sen B., Xie Z., Case N., Styner M., Rubin C.T., Rubin J. Mechanical signal influence on mesenchymal stem cell fate is enhanced by incorporation of refractory periods into the loading regimen. J Biomech 2011, 44:593-599.
    • (2011) J Biomech , vol.44 , pp. 593-599
    • Sen, B.1    Xie, Z.2    Case, N.3    Styner, M.4    Rubin, C.T.5    Rubin, J.6
  • 14
    • 84862788783 scopus 로고    scopus 로고
    • Mechanical stretch inhibits adipogenesis and stimulates osteogenesis of adipose stem cells
    • Yang X., Cai X., Wang J., Tang H., Yuan Q., Gong P., et al. Mechanical stretch inhibits adipogenesis and stimulates osteogenesis of adipose stem cells. Cell Prolif 2012, 45:158-166.
    • (2012) Cell Prolif , vol.45 , pp. 158-166
    • Yang, X.1    Cai, X.2    Wang, J.3    Tang, H.4    Yuan, Q.5    Gong, P.6
  • 15
    • 77957935850 scopus 로고    scopus 로고
    • Mechanical activation of beta-catenin regulates phenotype in adult murine marrow-derived mesenchymal stem cells
    • Case N., Xie Z., Sen B., Styner M., Zou M., O'Conor C., et al. Mechanical activation of beta-catenin regulates phenotype in adult murine marrow-derived mesenchymal stem cells. J Orthop Res 2010, 28:1531-1538.
    • (2010) J Orthop Res , vol.28 , pp. 1531-1538
    • Case, N.1    Xie, Z.2    Sen, B.3    Styner, M.4    Zou, M.5    O'Conor, C.6
  • 16
    • 57349115394 scopus 로고    scopus 로고
    • Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal
    • Sen B., Xie Z., Case N., Ma M., Rubin C., Rubin J. Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal. Endocrinology 2008, 149:6065-6075.
    • (2008) Endocrinology , vol.149 , pp. 6065-6075
    • Sen, B.1    Xie, Z.2    Case, N.3    Ma, M.4    Rubin, C.5    Rubin, J.6
  • 17
    • 14844282050 scopus 로고    scopus 로고
    • Regulation of PPARgamma activity during adipogenesis
    • Farmer S.R. Regulation of PPARgamma activity during adipogenesis. Int J Obes (Lond) 2005, 29(Suppl. 1):S13-S16.
    • (2005) Int J Obes (Lond) , vol.29 , Issue.SUPPL. 1
    • Farmer, S.R.1
  • 18
    • 33746483284 scopus 로고    scopus 로고
    • Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin
    • Liu J., Wang H., Zuo Y., Farmer S.R. Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin. Mol Cell Biol 2006, 26:5827-5837.
    • (2006) Mol Cell Biol , vol.26 , pp. 5827-5837
    • Liu, J.1    Wang, H.2    Zuo, Y.3    Farmer, S.R.4
  • 19
    • 2142652189 scopus 로고    scopus 로고
    • PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
    • Akune T., Ohba S., Kamekura S., Yamaguchi M., Chung U.I., Kubota N., et al. PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J Clin Invest 2004, 113:846-855.
    • (2004) J Clin Invest , vol.113 , pp. 846-855
    • Akune, T.1    Ohba, S.2    Kamekura, S.3    Yamaguchi, M.4    Chung, U.I.5    Kubota, N.6
  • 20
    • 0026525053 scopus 로고
    • Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression
    • Graves R.A., Tontonoz P., Spiegelman B.M. Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression. Mol Cell Biol 1992, 12:1202-1208.
    • (1992) Mol Cell Biol , vol.12 , pp. 1202-1208
    • Graves, R.A.1    Tontonoz, P.2    Spiegelman, B.M.3
  • 21
    • 1442332442 scopus 로고    scopus 로고
    • Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential
    • Peister A., Mellad J.A., Larson B.L., Hall B.M., Gibson L.F., Prockop D.J. Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential. Blood 2004, 103:1662-1668.
    • (2004) Blood , vol.103 , pp. 1662-1668
    • Peister, A.1    Mellad, J.A.2    Larson, B.L.3    Hall, B.M.4    Gibson, L.F.5    Prockop, D.J.6
  • 22
    • 49149128079 scopus 로고    scopus 로고
    • Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population
    • Kalajzic Z., Li H., Wang L.P., Jiang X., Lamothe K., Adams D.J., et al. Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population. Bone 2008, 43:501-510.
    • (2008) Bone , vol.43 , pp. 501-510
    • Kalajzic, Z.1    Li, H.2    Wang, L.P.3    Jiang, X.4    Lamothe, K.5    Adams, D.J.6
  • 23
    • 84870391538 scopus 로고    scopus 로고
    • Mapping the interrelationship of the adipogenic and osteogenic lineage with visual reporters
    • [Abstract M097]
    • Kronenberg K., Harrison J., Rowe D.W. Mapping the interrelationship of the adipogenic and osteogenic lineage with visual reporters. J Bone Miner Res 2008, 23. [Abstract M097].
    • (2008) J Bone Miner Res , vol.23
    • Kronenberg, K.1    Harrison, J.2    Rowe, D.W.3
  • 24
    • 0033859468 scopus 로고    scopus 로고
    • Inhibitory effect of NF-kappaB on 1,25-dihydroxyvitamin D(3) and retinoid X receptor function
    • Farmer P.K., He X., Schmitz M.L., Rubin J., Nanes M.S. Inhibitory effect of NF-kappaB on 1,25-dihydroxyvitamin D(3) and retinoid X receptor function. Am J Physiol Endocrinol Metab 2000, 279:E213-E220.
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Farmer, P.K.1    He, X.2    Schmitz, M.L.3    Rubin, J.4    Nanes, M.S.5
  • 25
    • 57649237947 scopus 로고    scopus 로고
    • Beta-catenin levels influence rapid mechanical responses in osteoblasts
    • Case N., Ma M., Sen B., Xie Z., Gross T.S., Rubin J. Beta-catenin levels influence rapid mechanical responses in osteoblasts. J Biol Chem 2008, 283:29196-29205.
    • (2008) J Biol Chem , vol.283 , pp. 29196-29205
    • Case, N.1    Ma, M.2    Sen, B.3    Xie, Z.4    Gross, T.S.5    Rubin, J.6
  • 27
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann J.M., Moore L.B., Smith-Oliver T.A., Wilkison W.O., Willson T.M., Kliewer S.A. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 1995, 270:12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 28
    • 78049235602 scopus 로고    scopus 로고
    • Indomethacin promotes adipogenesis of mesenchymal stem cells through a cyclooxygenase independent mechanism
    • Styner M., Sen B., Xie Z., Case N., Rubin J. Indomethacin promotes adipogenesis of mesenchymal stem cells through a cyclooxygenase independent mechanism. J Cell Biochem 2010, 111:1042-1050.
    • (2010) J Cell Biochem , vol.111 , pp. 1042-1050
    • Styner, M.1    Sen, B.2    Xie, Z.3    Case, N.4    Rubin, J.5
  • 30
    • 77950188542 scopus 로고    scopus 로고
    • Development of a rapid culture method to induce adipocyte differentiation of human bone marrow-derived mesenchymal stem cells
    • Ninomiya Y., Sugahara-Yamashita Y., Nakachi Y., Tokuzawa Y., Okazaki Y., Nishiyama M. Development of a rapid culture method to induce adipocyte differentiation of human bone marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun 2010, 394:303-308.
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 303-308
    • Ninomiya, Y.1    Sugahara-Yamashita, Y.2    Nakachi, Y.3    Tokuzawa, Y.4    Okazaki, Y.5    Nishiyama, M.6
  • 31
    • 0037609723 scopus 로고    scopus 로고
    • Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice
    • Bonyadi M., Waldman S.D., Liu D., Aubin J.E., Grynpas M.D., Stanford W.L. Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice. Proc Natl Acad Sci U S A 2003, 100:5840-5845.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 5840-5845
    • Bonyadi, M.1    Waldman, S.D.2    Liu, D.3    Aubin, J.E.4    Grynpas, M.D.5    Stanford, W.L.6
  • 32
    • 0036090467 scopus 로고    scopus 로고
    • Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation
    • Lecka-Czernik B., Moerman E.J., Grant D.F., Lehmann J.M., Manolagas S.C., Jilka R.L. Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation. Endocrinology 2002, 143:2376-2384.
    • (2002) Endocrinology , vol.143 , pp. 2376-2384
    • Lecka-Czernik, B.1    Moerman, E.J.2    Grant, D.F.3    Lehmann, J.M.4    Manolagas, S.C.5    Jilka, R.L.6
  • 33
    • 7244232742 scopus 로고    scopus 로고
    • Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes
    • Liu J., Farmer S.R. Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes. J Biol Chem 2004, 279:45020-45027.
    • (2004) J Biol Chem , vol.279 , pp. 45020-45027
    • Liu, J.1    Farmer, S.R.2
  • 34
    • 78650484935 scopus 로고    scopus 로고
    • Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes
    • Taelman V.F., Dobrowolski R., Plouhinec J.L., Fuentealba L.C., Vorwald P.P., Gumper I., et al. Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell 2010, 143:1136-1148.
    • (2010) Cell , vol.143 , pp. 1136-1148
    • Taelman, V.F.1    Dobrowolski, R.2    Plouhinec, J.L.3    Fuentealba, L.C.4    Vorwald, P.P.5    Gumper, I.6
  • 35
    • 80655144734 scopus 로고    scopus 로고
    • Mechanical regulation of glycogen synthase kinase 3beta (GSK3beta) in mesenchymal stem cells is dependent on Akt protein serine 473 phosphorylation via mTORC2 protein
    • Case N., Thomas J., Sen B., Styner M., Xie Z., Galior K., et al. Mechanical regulation of glycogen synthase kinase 3beta (GSK3beta) in mesenchymal stem cells is dependent on Akt protein serine 473 phosphorylation via mTORC2 protein. J Biol Chem 2011, 286:39450-39456.
    • (2011) J Biol Chem , vol.286 , pp. 39450-39456
    • Case, N.1    Thomas, J.2    Sen, B.3    Styner, M.4    Xie, Z.5    Galior, K.6
  • 36
    • 77952007543 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony
    • Foster K.G., Fingar D.C. Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony. J Biol Chem 2010, 285:14071-14077.
    • (2010) J Biol Chem , vol.285 , pp. 14071-14077
    • Foster, K.G.1    Fingar, D.C.2
  • 37
    • 80054920324 scopus 로고    scopus 로고
    • Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells
    • Sen B., Guilluy C., Xie Z., Case N., Styner M., Thomas J., et al. Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells. Stem Cells 2011, 29:1829-1836.
    • (2011) Stem Cells , vol.29 , pp. 1829-1836
    • Sen, B.1    Guilluy, C.2    Xie, Z.3    Case, N.4    Styner, M.5    Thomas, J.6
  • 38
    • 84865363133 scopus 로고    scopus 로고
    • Treadmill training regulates beta-catenin signaling through phosphorylation of GSK-3beta in lumbar vertebrae of ovariectomized rats
    • Bu S., Chen Y., Wang S., Zhang F., Ji G. Treadmill training regulates beta-catenin signaling through phosphorylation of GSK-3beta in lumbar vertebrae of ovariectomized rats. Eur J Appl Physiol 2012, 112:3295-3304.
    • (2012) Eur J Appl Physiol , vol.112 , pp. 3295-3304
    • Bu, S.1    Chen, Y.2    Wang, S.3    Zhang, F.4    Ji, G.5


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