Inhibition of UDP-glucuronosyltransferases (UGTs) activity by constituents of Schisandra chinensis

Phytotherapy Research

Volumn 29, Issue 10, 2015, Pages 1658-1664

  Song, Jin Hui ^a   Cui, Li ^a   An, Li Bin ^a   Li, Wen Tao ^a   Fang, Zhong Ze ^c   Zhang, Yan Yan ^d   Dong, Pei Pei ^e   Wu, Xue ^b   Wang, Li Xuan ^b   Gonzalez, Frank J ^f   Sun, Xiao Yu ^b   Zhao, De Wei ^a  

^a DALIAN UNIVERSITY   (China)

^b Personalized Treatment and Diagnosis Center   (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

^d JINZHOU MEDICAL UNIVERSITY   (China)

^e DALIAN MEDICAL UNIVERSITY   (China)

^f NATIONAL CANCER INSTITUTE   (United States)

Author keywords

herb drug interaction; in silico; in vitro; Schisandra chinensis; UDP glucuronosyltransferases (UGTs)

Indexed keywords

GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A9; GLUCURONOSYLTRANSFERASE 2B7; GOMISIN; GOMISIN A; SCHISANDRIN; SCHISANDRIN C; SCHISANDROL A; SCHISANTHERIN A; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; CYCLOOCTANE DERIVATIVE; HERBACEOUS AGENT; LIGNAN; PLANT EXTRACT; POLYCYCLIC HYDROCARBON; SCHISANHENOL; SCHIZANDRER A; SCHIZANDRIN; SCHIZANDRIN A; SCHIZANDRIN C;

ARTICLE; CHEMICAL STRUCTURE; COMPUTER MODEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG STRUCTURE; ENZYME INHIBITION; HYDROGEN BOND; IN VITRO STUDY; INHIBITION KINETICS; MOLECULAR DOCKING; SCHISANDRA CHINENSIS; STRUCTURE ACTIVITY RELATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; HERB DRUG INTERACTION; RAT; SCHISANDRA;

ANIMALS; CYCLOOCTANES; DIOXOLES; DRUGS, CHINESE HERBAL; GLUCURONOSYLTRANSFERASE; HERB-DRUG INTERACTIONS; LIGNANS; PLANT EXTRACTS; POLYCYCLIC COMPOUNDS; RATS; SCHISANDRA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84943582013     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5395     Document Type: Article

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