Engineering Methylobacterium extorquens for de novo synthesis of the sesquiterpenoid α-humulene from methanol

Metabolic Engineering

Volumn 32, Issue , 2015, Pages 82-94

  Sonntag, Frank ^a   Kroner, Cora ^a   Lubuta, Patrice ^a   Peyraud, Rémi ^b   Horst, Angelika ^a   Buchhaupt, Markus ^a   Schrader, Jens ^a  

^a KARL WINNACKER INSTITUT   (Germany)

^b LABORATOIRE DES INTERACTIONS PLANTES MICROORGANISMES LIPM   (France)

Author keywords

Alpha humulene; Diapocarotenoids; Methanol; Methylobacterium extorquens; Mevalonate pathway; Terpenoids

Indexed keywords

DRUG PRODUCTS; LIPIDS; METABOLIC ENGINEERING; SYNTHESIS (CHEMICAL); YEAST;

ALPHA-HUMULENE; DIAPOCAROTENOIDS; METHYLOBACTERIUM; MEVALONATE PATHWAY; TERPENOIDS;

METHANOL;

ALPHA HUMULENE SYNTHASE; CAROTENOID; DODECANE; FARNESYL DIPHOSPHATE; HUMULENE; METHANOL; MEVALONIC ACID; UNCLASSIFIED DRUG; CULTURE MEDIUM; SESQUITERPENE;

ARTICLE; BACTERIAL STRAIN; BIOSYNTHESIS; CARBON SOURCE; CLONING; FERMENTATION; METABOLIC ENGINEERING; METHYLOBACTERIUM EXTORQUENS; MYXOCOCCUS XANTHUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIBOSOME; SACCHAROMYCES CEREVISIAE; ZINGIBER ZERUMBET; BIOREACTOR; COMPUTER SIMULATION; CULTURE MEDIUM; GENETICS; METABOLISM; PLASMID; PROCEDURES;

BIOREACTORS; CAROTENOIDS; COMPUTER SIMULATION; CULTURE MEDIA; FERMENTATION; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; METHANOL; METHYLOBACTERIUM EXTORQUENS; MEVALONIC ACID; PLASMIDS; SESQUITERPENES;

EID: 84943572735     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.09.004     Document Type: Article

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