A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro

Neuroscience Letters

Volumn 607, Issue , 2015, Pages 83-89

  Hammond, Sean L ^a   Safe, Stephen ^b,c   Tjalkens, Ronald B ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Dopamine; Neuroprotection; NR4A receptors; Nurr1; Transcriptional regulation

Indexed keywords

1,1 BIS (3' INDOLYL) 1 (4 CHLOROPHENYL) METHANE; BETA ACTIN; MESSENGER RNA; NEUROPROTECTIVE AGENT; NUCLEAR RECEPTOR RELATED FACTOR 1; OXIDOPAMINE; PLANT MEDICINAL PRODUCT; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2; 1,1-BIS(3'-INDOLYL)-1-(4-CHLOROPHENYL)METHANE; DOPAMINE; INDOLE DERIVATIVE;

ARTICLE; CELL SURVIVAL; CELL VIABILITY ASSAY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IN VITRO STUDY; NEUROPROTECTION; NEUROTOXICITY; PARKINSON DISEASE; PRIORITY JOURNAL; RNA INTERFERENCE; AGONISTS; ANIMAL; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MOUSE; PRIMARY CELL CULTURE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; DOPAMINE; DOPAMINERGIC NEURONS; GENE EXPRESSION; HUMANS; INDOLES; MICE; NEUROPROTECTIVE AGENTS; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 2; OXIDOPAMINE; PRIMARY CELL CULTURE;

EID: 84943552980     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2015.09.015     Document Type: Article

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