Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca2+Release Patterns in Cardiomyocytes

PLoS Computational Biology

Volumn 11, Issue 9, 2015, Pages

  Rajagopal, Vijay ^a,b,c   Bass, Gregory ^c   Walker, Cameron G ^d   Crossman, David J ^d   Petzer, Amorita ^e   Hickey, Anthony ^e   Siekmann, Ivo ^a   Hoshijima, Masahiko ^f,g   Ellisman, Mark H ^g   Crampin, Edmund J ^c,h,i   Soeller, Christian ^d,j  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c The University of Melbourne   (Australia)

^d UNIVERSITY OF AUCKLAND   (New Zealand)

^e UNIVERSITY OF AUCKLAND   (New Zealand)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF MELBOURNE   (Australia)

ⁱ UNIVERSITY OF MELBOURNE   (Australia)

^j UNIVERSITY OF EXETER   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; MITOCHONDRIA;

CA 2+; CARDIAC MUSCLES; CARDIOMYOCYTES; CLUSTER DISTRIBUTIONS; INTRACELLULAR CALCIUM; MITOCHONDRIAS; MUSCLE CELL; MYOFIBRILS; RELEASE PATTERN; SPATIO-TEMPORAL DYNAMICS;

RATS;

CALCIUM ION; RYANODINE RECEPTOR; CALCIUM;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL ULTRASTRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLUORESCENCE ANALYSIS; HEART MUSCLE CELL; MITOCHONDRION; MUSCLE FIBRIL; NONHUMAN; PROTEIN FUNCTION; RAT; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; CALCIUM SIGNALING; CARDIAC MUSCLE CELL; CHEMISTRY; COMPUTER SIMULATION; MALE; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ANIMALS; CALCIUM; CALCIUM SIGNALING; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; MALE; MITOCHONDRIA; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; MYOFIBRILS; RATS; RATS, WISTAR; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 84943532946     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004417     Document Type: Article

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